#=GF ID   DUF4897
#=GF AC   PF16238.9
#=GF DE   Domain of unknown function (DUF4897)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target TM0491
#=GF GA   25.00 25.00;
#=GF TC   25.40 25.40;
#=GF NC   24.90 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR032604;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A small family of uncharacterized proteins around 200 residues 
#=GF CC   in length and found in various Thermotoga species.  The function
#=GF CC   of this family is unknown.
#=GF SQ   29
#=GS I2F6J3_9BACT/32-194       AC I2F6J3.1
#=GS W0JMM3_9EURY/59-223       AC W0JMM3.1
#=GS U1NWR3_9EURY/56-213       AC U1NWR3.1
#=GS F7YWP6_9THEM/32-189       AC F7YWP6.1
#=GS A0A6A9T5L3_9EURY/50-212   AC A0A6A9T5L3.1
#=GS A0A7D5KET0_9EURY/31-183   AC A0A7D5KET0.1
#=GS A0A6G2HCP9_9EURY/71-214   AC A0A6G2HCP9.1
#=GS Q9WYW1_THEMA/35-191       AC Q9WYW1.1
#=GS A0A1M5TZI3_9BACT/32-188   AC A0A1M5TZI3.1
#=GS A0A7D4Y4N2_9EURY/42-205   AC A0A7D4Y4N2.1
#=GS A0A6B0VGL3_9EURY/39-191   AC A0A6B0VGL3.1
#=GS A0A346PVH8_9EURY/70-222   AC A0A346PVH8.1
#=GS A0A0X1KQH3_9THEM/32-188   AC A0A0X1KQH3.1
#=GS B7ICK2_THEAB/32-188       AC B7ICK2.1
#=GS W0K1U8_9EURY/50-203       AC W0K1U8.1
#=GS A8F8U8_PSELT/32-189       AC A8F8U8.1
#=GS A0A1Q6DXT9_9EURY/31-198   AC A0A1Q6DXT9.1
#=GS A0A7D5HXJ0_9EURY/40-202   AC A0A7D5HXJ0.1
#=GS A7HNP0_FERNB/33-193       AC A7HNP0.1
#=GS H2J376_MARPK/42-203       AC H2J376.1
#=GS C5CGJ1_KOSOT/32-193       AC C5CGJ1.1
#=GS A0A1J1AD27_9EURY/46-209   AC A0A1J1AD27.1
#=GS R4VVM7_9EURY/33-189       AC R4VVM7.1
#=GS A0A1G6IKG8_9BACT/39-197   AC A0A1G6IKG8.1
#=GS A0A0C7P2J5_DEFTU/40-201   AC A0A0C7P2J5.1
#=GS A0A7G1G3P8_9BACT/38-196   AC A0A7G1G3P8.1
#=GS A0A5D0RQQ9_9BACT/32-193   AC A0A5D0RQQ9.1
#=GS A0A0G2ZEI6_9BACT/32-193   AC A0A0G2ZEI6.1
#=GS A0A3N6MCF9_9EURY/124-254  AC A0A3N6MCF9.1
I2F6J3_9BACT/32-194                  ......................................................idt---LSSTSNYSYDYEGRATLDIETEIIFN.KPDQMTQFLE..QYDKPQEEq.......laDFQESM....TQFS....E....SFD....RLM..LVE..SFQSTATV..lS..S...N...RVK.VV.EH.AVIAGFAAVE....NGVVNT.DMG.DMEFD...LTGDAYsLTISIPTDAKVINLDPAPTVAADgNEFIWTN.TGKTIFPKIQFS..............
W0JMM3_9EURY/59-223                  ....................evelqsdgnatvsvdyryhigndsetaeqwdeleqdv-----------------------------.-----NSNDQ..TYIDEEAS..........SWQETL....EEGE....N....ETG....RDM..NVS..GFTVETNEsttP..R...E...YGH.VQ.FT.FDWESFAYVE....LNRIEA.GDA.LTGFM...LDDDTE.LQIGWPDTYNVTAVDPEPTTSED.NWATWDG.DD----------agsdaqppkvel..
U1NWR3_9EURY/56-213                  ........................................avvvdldsegdgaltvg---------------------VPFDLTIEaEENDFQAFVEseTEQQAQLD..........RFESRL....ASVA....AemeaETG....REM..TVT..DTSMTTET..rE..N...G...TLGlVV.LT.ATWEGLAASN....ESHLVLgPPF.DSGFN...--TDRT.VVIQPPAQHQVVSTTPTPSTDA-.DQLVWNE.GQS---------ldgfelv.......
F7YWP6_9THEM/32-189                  .........................................................FEIVYYRTKMEYDYNGSAVFTTTAGLFFK.DKNKQASYVQ..QYQQVSLD..........TFRKYF....EDVS....K....KIG....REI..EVV..SMESSINE...R..A...G...ILE.IV.EV.AKLNNAAVVT....DGVVDT.QMK.DITLS...ASGDSE.IVIVIPKDAVVVSVEPTPTKIVE.NQIYWQPiGSRMAFPRVVFK..............
A0A6A9T5L3_9EURY/50-212              teiepdgdavwevqyrvrlatdeeerafeelradvesdpaaytdrfsermastaaaa-----------------------------.----------..--------..........------....---E....N....ATG....REM..TVS..NTTVTAER...R..E...LpqsYGV.LT.YR.FEWSNFAAVE....DDRLVV.GDA.VDELF...LDEDSS.LIVSWPADYGVAEVSPEPTETRE.NAVVWRG.------------pidftdgqpritle
A0A7D5KET0_9EURY/31-183              ....................................................fgval----------EADGSAHVTLATTFNLTTD.GERQAFQALR..QNETAREQr.......teRFAARM....RAIAtraeN....ETG....RAM..QIT..DAGISFRE...R..N...D...TGV.VT.LS.VTWDGLAAQQ...gDRLVLK.EPF.DSEFS...L--DRP.FRVTRPDGYELASVSPEPTERSQ.NDAVWSG.G-----------tdfdgf........
A0A6G2HCP9_9EURY/71-214              ...............tieyrtrldtdddeaafeelrrdieadpeaytvefadrmsat-----------------------------.----------..--------..........-----A....EGAS....T....ATG....REM..AIS..DMRVDAER...R..QlprE...YGI.VT.YT.FQWSNFAAVD....GDRIAA.GDA.IDGLF...LDDASE.LRIGWPDDRALVEATPSPTETRE.TAVVWRG.P-----------tsfae.........
Q9WYW1_THEMA/35-191                  .........................................................FEIVYYRSTMEYDYSGNATFTTSAKLYFK.DEKKKEEYKI..NYASASKE..........ELNKYF....SQIS....K....EVG....REI..VPL..DYNVRVED...T..G...G...MLE.VT.ET.TLLRGAAQVK....GDVLDT.SMG.SLTMN...VAGETE.IVVKLPEDAAVISVTPTPSEREN.NTLIWRP.DSSMVFPKVIFK..............
A0A1M5TZI3_9BACT/32-188              .........................................................FEITFYQTKVEIDYSENSTITTLAVLSFN.KQQDMFNYME..SYNNAASS..........TFIDYF....KKIS....D....EIG....KQL..VVV..NYNNKATE...R..A...G...VLE.IE.EQ.AVIKNLVTKK....DKYYEL.SMG.KLPIN...SNNDSE.FIIYLPQNTKVISIDPTPTTISN.NTLKWNG.GALEYFPTVIY-t.............
A0A7D4Y4N2_9EURY/42-205              ......................eadldedgdarwtveyrvaldsentteafeslqqd-----------------------------.IERSTS----..DYRGQFAS..........RMESTV....ATAE....N....ATG....REM..AVE..NVSVEATTs.pI..S...G...EYG.IV.RYgFDWVGFADAS....DGQLAV.DEV.LAGMF...LDADTE.LTIEWPEEYRISLVEPEPDSEDE.NSVTWTG.PR----------efdvgqprvvlr..
A0A6B0VGL3_9EURY/39-191              .....................................................vhva---------LEADGDATVTLVSVYDLTDE.DERDAFETLR..EDEKTQADl.......leRFSERL....EGVA....D....DVDtdadREK..SVE..SKSVDVRT...N..E...D...SGI.VT.FS.AFWDELAAVE....GETVVL.-ME.PFASG...FESDRS.LIVTIPDGTTIESVTPEPTIHEE.SAVNWDG.ETEL--------dgf...........
A0A346PVH8_9EURY/70-222              ........................evilqengsatftvdyrfentssedwetlrddv-----------------------------.-----EENPD..SYAVAELS..........DWNEIL....EKGE....N....ETD....REM..ELS..DASVAADTsstP..R...D...MGH.VQ.VS.FTWSAFAHVE....LNRMEV.GGA.LAGFT...LVDDTT.LQLFWPDEYVVRDVEPTPENPPD.ESVLWDG.DG----------tefs..........
A0A0X1KQH3_9THEM/32-188              .........................................................FEVVYYRSRMEYDYSGAATFTTTAGLFFK.DASKQQQYLQ..NYRQSSLE..........QFKQYF....AEVS....K....RLG....RQI..EVI..SMESTVTE...R..S...G...ILE.VM.EK.AVLSNVAVVE....QDVVDT.SLR.DVSIN...AVADSE.IVVVIPEDAVVLSVEPTPVRTLD.NQIYWKP.TGSMTFPRVVF-r.............
B7ICK2_THEAB/32-188                  .........................................................FDITFYKTVVETDYSDTATITTIAGLSFK.DEKSMYEYKE..SYTNASSK..........TFLNYF....EQIS....K....EIG....KTI..TVV..SYENSAKE...R..A...G...ILE.IE.EV.AVLKNLVDVS....NNTYTL.NMG.NIQIN...PNPNSL.FIVYIPKDSILVSSNPTPTSFEN.NKLSWDG.ESLKNFPTVIY-r.............
W0K1U8_9EURY/50-203                  ..................slqedgdaawtftyrtrlsndnetaafeslqndirtnts-----------------------------.----------..NYVGQFED..........RITATV....DAAE....N....TTG....RQM..AVE..NVSVSTRVnslN..E...E...SLG.VVtYH.FEWQGFAETE....ENAIAA.GDA.LEGFY...LDNETS.LTVSWPEGYETVEVAPEATQPRE.NAVQWRG.------------plefg.........
A8F8U8_PSELT/32-189                  .........................................................YEIAYYRSKMEYDYTGEATFTATAGLFFK.DKNKQQQYID..QYQQASLS..........TFKSYF....DDVS....E....KVG....RNI..EVI..SMNSTMTE...R..S...G...ILE.VV.ET.ARLLNAASVT....NGIVDT.SLK.DISIY...SVNDSQ.IVVVVPEGADILTIEPTPTKIVE.NAIYWQPsESSMSFPRVIFK..............
A0A1Q6DXT9_9EURY/31-198              ....................................................fktny------QITLNNDTSANWTIENRIKLETDsQENQFQKYLS..NITETETNlf......kdNIKAIV....STAS....N....STQ....RKM..SASnfSLNGTIEQ..gI..T...G...TYG.VI.HYnFHWTNFTVID....NEKIK-.-LG.DVFVNglyLSETDT.LTIHYPTGYKIHSIDPEPTKIQD.KELIWKG.PN----------dfepnnpeillk..
A0A7D5HXJ0_9EURY/40-202              ............vdltvdvaengsatwtvtyrlalatenetaafedlqrdvranrsa-----------------------------.----------..-YLDPFAE..........RIRTTV....RTAE....N....ATG....RPM..NAT..AFSVSTRV..qS..I...Gs.qYGV.VA.YQ.FTWHGFAAVD....GRTVRA.GDA.IAGFY...LDEDTT.LTLSAPEDYRVASVSPPPTTRSE.NAVGWEG.------------pvtftdeqpr....
A7HNP0_FERNB/33-193                  .........................................................FDVVYYDSDIFSDYSKIATITTVSGLKFK.SEKKESEYIN..TYKETSKE..........TFEKYF....SQVS....K....EIG....KDI..KVL..DVDFSWRK...R..E...G...ILE.IT.EK.VTLSGLVQNQimdgKEIYIL.DMG.KVKMN...AIGNAN.LKVHLPGDAVLITVEPTPTTQSA.NFVVWSG.NDILYFPEIKYK..............
H2J376_MARPK/42-203                  .........................................................FKVIKSDNYYYINDDKSVVMFSKVEIQAE.DEKSYNRLIE..NYDKPDEEk.......rkAYEQFL....SKLT....E....NTG....RDF..KLV..SLESSLTT..nN..N...N..yTIY.VN.EK.AVIFGFIKDL...gNNKYEF.SLN.SQKMN...LANST-.LYIYKPKNWEFIETYPQPTEITE.DYLLWKD.AGEIEFPTIKLE..............
C5CGJ1_KOSOT/32-193                  ........................................................v-ETIRYTSDYRYSFDGTVIMDSAVDLKFL.KPSQIEKFLE..QFQKPASEk.......isEFQKSL....DGLS....S....KVN....RTM..LVQ..DFQSTATQ..lD..Y...D...VVR.VE.EY.AVVKGFATVS....DGKVNT.SLG.DMEIN...LADESF.LTFSLPKNAKIISATPTPSKILEnNVLLWTG.DGVIRFPEVIFE..............
A0A1J1AD27_9EURY/46-209              ...................................................isadva-------------ENGTATFQIEYAIRLD.DENDSQAFDE..LANDIEQNesayvsrfadRMQNTV....SAAE....T....STG....RSM..TVR..DFGVTARTs.pTlgN...Q...YGT.VT.YT.ATWENFANVT....NGDIQV.GDA.LAGLF...LDEETR.LRIEWPETYQRATVDPAPTGSSA.GEVVWEG.------------prqfetgqpalt..
R4VVM7_9EURY/33-189                  .....................................................qerv--------NVDLQADGDAIVTTVYTYDLE.DDAQQQSFAN..LEDERENLs........tRYEARLwgvaESVS....N....ETG....REM..AIQ..DVEATFDR...R..D...G...VGV.VR.LS.ATWTNLAAID....GDELVL.SAPfDDGFD...---SGRpLVVRAPEGEEIVDTSVTPTEQAD.GQATWSA.EADL--------sgfevtm.......
A0A1G6IKG8_9BACT/39-197              .........................................................YDILNSNSIFIINEDQSVAINTNITMKAE.DDNSFNQLIE..NFNTPDEEk.......keAYVDNF....AQIM....K....NIE....RPF..EVI..SYESTMST...S..K...P...NLT.IE.ET.VTVMGFTDRL...nSNTLEF.SLP.GQPLN...VQD-S-.IVIEYPRNWQIQSIIPQPTQRGE.NFVIYEQ.EGQIDFPTIVF-d.............
A0A0C7P2J5_DEFTU/40-201              .......................................................fh--VVSRVIDFNIYEDLSVDFSTKVDIQVE.REKDFSTLVS..SFGTSDEEk.......ltMFQETL....DNLE....K....QVP....RDF..VVL..SYDSAVES...E..Y...P...FIY.VD.ET.VKLKGFVIEK...eDGTIEF.SLP.NQLLS...GENENVkVTIRFPEHWKVVSVEPDPNYIEQ.NTIAYSY.IGTRNYPTVQF-v.............
A0A7G1G3P8_9BACT/38-196              ........................................................y-DILSKNIIFNINENGITSLKLTTTIKAQ.DKKSFNYLLN..GYKRSDIE..........KSKGYE....KIFN....E....KNN....KNIycKVL..NYKSIINT...S..E...L...NIF.VE.ET.MDLSGIINKN....NNELIF.NFP.IKRLN...IDANSN.LYVYLPENWTLKESIPTPSKNLG.TYLLWNN.VGTIDFSKIVL-n.............
A0A5D0RQQ9_9BACT/32-193              ........................................................v-ETVFYDSEYEYDANGTVIMRSTMLLRFD.KPSQIEQFLG..QFDKDKETk.......isEFQQSV....DQIS....K....DLS....RSM..VVT..DFASTATQ..vA..S...D...RVE.VK.EY.SVIKGFAGVQ....NGQVNT.SIG.ELNID...LQDDSK.LTFLLPPDSKVLSVAPTPTYSPQsNIFIWEG.TGEIRFPEVIF-t.............
A0A0G2ZEI6_9BACT/32-193              ........................................................i-ETIAYSSNYSYDTEGRVKMDSVMEIKFL.KPQQIDGFLE..QFNKSPAEk.......lsEFQKSL....EDFS....S....KLG....RML..TVE..DFQSTATV..iS..Y...N...VVK.VE.EV.AVVRGFASVN....NGRVNT.SLG.DVELD...LSGDSV.LTIALPVGAKVISIDPQPTSRPAdNLLIWSN.AGRIKFPEVVF-v.............
A0A3N6MCF9_9EURY/124-254             ............................................enwealrddvean-----------------------------.--------SE..AYAEKERN..........DWNEIL....VEGA....N....ETG....RDM..EIS..DVTVETDTssaP..R...N...MGH.VE.FT.FRWSSFAHVE....LNRIEA.GDA.LAGFT...LVDDTT.LQFFWPEEYAVREIDPSPDDPPD.NSIFWDG.DG----------teftd.........
#=GC seq_cons                        ..................................................................h..p.sttshhts.htl.hp.ctpp.pphhp..pappsptp..........papphh....pphu....p....csG....Rph..pVp..shssospp...p..p...s...hht.Vp..p.sshpuhAslp....ssplph.uhs.thshs...lss-op.LhlthPcshplholsPsPTptt-.NtlhWpu.ss..........s.............
//