#=GF ID   DUF4900
#=GF AC   PF16241.9
#=GF DE   Domain of unknown function (DUF4900)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target TM1126
#=GF GA   29.40 29.40;
#=GF TC   29.70 29.90;
#=GF NC   29.00 28.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR032601;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of uncharacterized proteins around 600
#=GF CC   residues in length and is mainly found in various  Thermotoga
#=GF CC   and Fervidobaterium species. The function of  this family is
#=GF CC   unknown.
#=GF SQ   32
#=GS A0A6M1TC65_9BACT/120-181  AC A0A6M1TC65.1
#=GS Q53W46_THET8/173-261      AC Q53W46.1
#=GS A0A5D3YQR2_9BACT/113-181  AC A0A5D3YQR2.1
#=GS A0A172TAT9_9DEIO/195-294  AC A0A172TAT9.1
#=GS A0A2K3UYC3_9DEIO/193-278  AC A0A2K3UYC3.1
#=GS A0A221SU74_9DEIO/155-242  AC A0A221SU74.1
#=GS A0A2K3UW63_9DEIO/190-297  AC A0A2K3UW63.1
#=GS A0A1B6Y9K2_9BACT/119-186  AC A0A1B6Y9K2.1
#=GS A0A0X1KU52_9THEM/150-230  AC A0A0X1KU52.1
#=GS A0A511N9U6_DEIC1/177-266  AC A0A511N9U6.1
#=GS E8UB09_DEIML/304-390      AC E8UB09.1
#=GS A0A399F794_9DEIN/222-305  AC A0A399F794.1
#=GS A0A2A2G8X5_9BACT/113-181  AC A0A2A2G8X5.1
#=GS A0A1U7NVB6_9DEIO/147-237  AC A0A1U7NVB6.1
#=GS A0A2Z3JCK1_9DEIO/226-319  AC A0A2Z3JCK1.1
#=GS A0A410P5G2_9BACT/181-258  AC A0A410P5G2.1
#=GS A0A6I0FLL9_9CLOT/102-175  AC A0A6I0FLL9.1
#=GS A0A2H5ZXD0_9BACT/203-290  AC A0A2H5ZXD0.1
#=GS A0A7C9HPD9_9DEIO/197-296  AC A0A7C9HPD9.1
#=GS A0A1U7NRY2_9DEIO/206-307  AC A0A1U7NRY2.1
#=GS A0A3M8G6F9_9BACT/158-225  AC A0A3M8G6F9.1
#=GS I6YTS8_MELRP/98-165       AC I6YTS8.1
#=GS A0A511N2C1_DEIC1/145-232  AC A0A511N2C1.1
#=GS F2NL52_MARHT/175-263      AC F2NL52.1
#=GS D7BJP2_MEISD/158-246      AC D7BJP2.1
#=GS A0A399EEB1_9DEIN/183-272  AC A0A399EEB1.1
#=GS D7BA89_MEISD/226-307      AC D7BA89.1
#=GS E4U9P4_OCEP5/152-237      AC E4U9P4.1
#=GS A0A2K3UYL3_9DEIO/154-240  AC A0A2K3UYL3.1
#=GS A0A521EDQ6_9BACT/109-181  AC A0A521EDQ6.1
#=GS B8E2W1_DICTD/143-234      AC B8E2W1.1
#=GS E4U4J7_OCEP5/217-304      AC E4U4J7.1
A0A6M1TC65_9BACT/120-181             ..............aiaiteagit---------------.-.---..----...-....-...--...-----KDAFSRYTYFTD--.....-.....-E.....E.....P.NSIRFYDADVFDGPVHTNDTMRIA..G....N....P..TF.R.GEVTS---py....
Q53W46_THET8/173-261                 ........................TYALPFVMVAEASLG.Q.ARR..NIVL...Q....G...EY...RFTIGRSSFARYALFTNVH.....A.....LP.....N.....G.TGVWFTDRTLFDGPVHTNGHFRFY..R....S....P..WF.G.GEVTSAGC......
A0A5D3YQR2_9BACT/113-181             ................skvktnrt---------------.-.---..----...E....A...VT...EVAVTRPSFSRYSYFTD--.....-.....-T.....E.....A.SNIYFYDGDVLNGPVHTNGTFNIA..G....S....P..EF.N.GPVSS---pn....
A0A172TAT9_9DEIO/195-294             ............tyrfyfkvpdlq---------VRGQLG.A.SSQ..NIQA...R....A...AQpegFLLISRQPFSRYALFTNHH.....FsdaedEA.....R.....G.ERVTFTDRTMFSGPVHTNQHFLFQ..G....T....P..WF.G.GSVSSAGC......
A0A2K3UYC3_9DEIO/193-278             .....................svq---------STGVSS.P.ARRvlNASS...D....G...LF...VLTFSRPSFATYAQFRNHT.....T.....SA....tT.....G.GALYFSDGEEFRGPVHTNETLRLS..G....N....P..KF.Y.GELTTAG-a.....
A0A221SU74_9DEIO/155-242             .......................q-YYVDYLVTSQGQSG.A.FNR..NVEV...N....G...TL...RISMGRAPLNQYLLLAD--.....D.....GG.....S.....Q.EENFFGTGMNYDGPVQINKNWMFA..G....S....P..VF.SmGAKTAAS-t.....
A0A2K3UW63_9DEIO/190-297             ...........gyrlyftvpplas----------AGTDG.P.ATQ..NLQA...RatssGaaaTY...FLSIGRPSFATYALFTNHHfqseaA.....EQ.....E.....G.KRINFTKRTIFSGPVHTNQHFLFE..GdaggQ....P..IF.W.GEVTSAGC......
A0A1B6Y9K2_9BACT/119-186             ................gdskvite---------------.-.---..----...-....-...--...-VLMRRDSFSKYSYFSDKE.....K.....TS.....S.....G.NNIYFYSSDEISGPIHTNGTFKMS..G....S....P..TF.Y.GHVSS---pn....
A0A0X1KU52_9THEM/150-230             pysvlvvsrnsvgkmesyalavla---------------.-.---..----...-....-...--...-----IDFLNKYAYFTERE.....T.....RP.....G.....G.GKIYFVTRDLIDGPMRSNDTINIW..G....N....P..IF.R.STVE----vgdv..
A0A511N9U6_DEIC1/177-266             ........................TYGVPYLVVVTGTKG.K.SQR..MTTL...L....G...EY...QFQLGRSSFARYGLFTNIH.....T.....SK.....A.....G.SNVVFTSNILYDGPVHTNGKFNFS.tG....T....P..YF.G.SYVTSVGC......
E8UB09_DEIML/304-390                 .....tvtknnqviaqstivsnpv---------------.-.---..--SL...R....D...VG...EMQLAQDSFSKYALFTNVH.....P.....--.....-.....-.STINFTGTTLFGGPVHTNQNFRFT..A....TngaqP..WF.G.GKVTSAGC......
A0A399F794_9DEIN/222-305             ............anptvvatrtlq---------------.-.---..-RGL...G....G...PF...QLKLSPPNFSAFAQFTNRQ.....L....tSV.....S.....G.SRVFLGDNAVYDGPIHTNEYYSFSagQ....S....P..LF.G.KTVTSAGC......
A0A2A2G8X5_9BACT/113-181             ............staetnstravv---------------.-.---..----...-....-...--...EAHITQDSFSRYAFFSN--.....-.....DE.....N.....-.-GVNFTSTDVINGPVHTNGTLNFS..G....T....P..TF.N.GPVSS---pnm...
A0A1U7NVB6_9DEIO/147-237             ........................TYYLDYSINGAANTF.G.NRR..NVVT...E....G...TM...RINLGRQSLNQFILLADDG....gS.....GS.....N.....G.SSGFFDTSSTYDGPVHVNKNWALS..G....N....P..TFlA.GATTSSS-f.....
A0A2Z3JCK1_9DEIO/226-319             ........lkatatsatgtravsa---------------.-.SAR..QFSD...R....K...IY...SLNVYKSSFARYALFTNHH.....F.....SS.....SsdegsA.NNIWFTSNTKFSGPVHTNQTFNFL..D....T....P..YF.G.GQITSAGC......
A0A410P5G2_9BACT/181-258             ...............nppvlktir---------------.-.---..--LW...Q....G...QF...TLTVLRANFAKFALFTSHH.....T.....TP.....S.....G.TTVWFTENTNFTGPVSTNERFSFA..N....N....PsgHF.S.DEVT----qhe...
A0A6I0FLL9_9CLOT/102-175             .......rstgwansnentkrtie---------------.-.---..----...-....-...--...-AQLTKRTFTQNVYLSN--.....-.....-N.....D.....G.SNIWWTSGDTVYGPMHTNTKLRVW..N....E....P..VF.Y.GRVTHS--nn....
A0A2H5ZXD0_9BACT/203-290             ......................qv--HLEYRVVSDGQVD.PqFRR..RVTL...R....G...NF...NVVLGNTSFAQWALFTHVH.....L.....TP.....D.....D.RDIWFTSRTSFDGPVHTNGEFRFA..F....F....P..KF.G.--------tpdaqt
A0A7C9HPD9_9DEIO/197-296             ..............gyrliftvpd-------VTVTGQAG.G.ATR..QVKVraaQ....D...EL...SLLIERPSLAPNALFTNHH.....Y.....LSgvsegK.....G.EGIYFTSRTLFSGPVHTNQHLNIV..G....K....P..WF.G.GAVSSAGC......
A0A1U7NRY2_9DEIO/206-307             ....yrlyfevpsalsqgvtgstt------------QRL.S.ARA..TTDG...K....G...EY...YLLISREPFAKFGLFTNRQfqspeA.....ER.....N.....N.TLITFTERTLFSGPVHTNGRFTFY..K....T....P..TF.W.GEVTSAGC......
A0A3M8G6F9_9BACT/158-225             .................dnievtt---------------.-.---..----...-....-...--...EVLMQRDSFSKYSYMTNSE.....L.....SS.....T.....G.GNIWFMSADNIYGPIHTNGTFKMS..G....N....P..SF.Y.GLITS---pn....
I6YTS8_MELRP/98-165                  ..............vanyrgvtst---------------.-.---..----...-....-...-I...RILLKPSSFSKYAYFSD--.....-.....-S.....E.....G.ANIWWTTRDTVWGPFHTNGQLRVA..D....E....P..VF.Y.GKVTI---dg....
A0A511N2C1_DEIC1/145-232             .......................d-YWMEYVIETTGNDK.Q.FKR..NVIT...S....G...NM...LVRLGRTYLNQFVLLADDG.....G.....ST.....G.....G.--NYYATGMNYDGPVHVNKNWRFA..G....S....P..QF.KyGATTNA--at....
F2NL52_MARHT/175-263                 ........................TYALPFVMVAEARIG.P.YRR..NVVL...Q....G...EY...RFVLGRSSFARYALFTNVH.....A.....LP.....N.....G.TGVWFTSRTLFDGPVHTNQQFRFY..R....T....P..WF.G.GEVTSAGC......
D7BJP2_MEISD/158-246                 .......................r-YRLPFVAYAQGERG.E.ARQ..ERYL...L....G...AY...EFDLGDALPSRYAMLLDNA.....Y.....DA.....R.....G.NLHLFDGGVVLEGRLHVAGLLGVR..D....N....P..WL.A.GAVTSGSC......
A0A399EEB1_9DEIN/183-272             .......................g-YALPYVMVVTASPGtP.YQR..NVLV...Q....G...EY...RFLLTNGSFARYALFTNRH.....R.....TK.....S.....N.SAVWFTSGTLFDGPVHTNERFRFS..F....N....P..WF.G.GYVTSAGC......
D7BA89_MEISD/226-307                 ........anqrlaqqvlerqygn---------------.-.---..----...-....-...RL...ALVLLPPSFAQFAQFTDFN.....A.....TG.....V.....GsERVWFYDSHLYGGPVHTNDVLAFG.gG....E....P..WF.G.GRVSSAGC......
E4U9P4_OCEP5/152-237                 ........................TYTAEYKVVATGTSG.N.GKR..RIQE...E....G...FL...TVKLGRASLSQWLFLVE--.....-.....DA.....G.....G.DRGFFPTGSVFDGPVHANSNWGFW..G....T....P..VF.R.GRITAS--dg....
A0A2K3UYL3_9DEIO/154-240             .......................r-YFVDYRVESTGQVG.S.FSR..NVNV...E....G...TL...GISMGRQYLNQFLLLSDDG.....G.....SK.....-.....-.EGNFYATGMNYDGPVHVNRNWRFA..G....T....P..NFsR.GATTAS--k.....
A0A521EDQ6_9BACT/109-181             ..............evnyegttle---------------.-.---..----...-....-...-T...EVLLQRDSFSKYSYFTDAE.....S.....MP.....N.....G.QTIWFGGNDAITGPVHTNGTFSIR..D....S....P..IF.N.GPVTSP--nm....
B8E2W1_DICTD/143-234                 ..ytyvytitclgqkvnfnptitl---------------.-.---..QVTV...T....G...KI...EGVLRKENFARFALFTDRH.....L.....MS.....D.....G.SRVWFTDRTKFYGPVHTNGQFAFA..Y....T....P..QF.F.DEVSSV--at....
E4U4J7_OCEP5/217-304                 ............gflakegtdvar---------------.-.HKI..EQAF...T....G...EL...RIDLRPPSFSHFMLFTNYQr..agA.....GA.....G.....A.ERVYFYDGTLFDGPVHTNDKFNFT..G....R....P..WF.G.DSVTSVGC......
#=GC seq_cons                        .......................p..............................p....u....h...plhls+sSFu+auhFTshp.....h.....ts.....s.....G.sslaFsssshasGPVHTNppapFs..s....s....P..hF.t.GtVTSs........
//