#=GF ID   DUF5044
#=GF AC   PF16447.9
#=GF DE   Domain of unknown function (DUF5044)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target SP16939A
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.40;
#=GF NC   24.50 24.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR032243;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several uncharacterized proteins around
#=GF CC   220 residues in length and is mainly found in various
#=GF CC   Clostridiales species. The function of this family is unknown.
#=GF SQ   17
#=GS G9YSI2_FLAPL/36-214      AC G9YSI2.1
#=GS A0A6N8FKR4_9BACI/35-197  AC A0A6N8FKR4.1
#=GS A0A433Y885_9BACL/31-194  AC A0A433Y885.1
#=GS G9YSI0_FLAPL/35-207      AC G9YSI0.1
#=GS A0A1H1DR45_9BACI/37-197  AC A0A1H1DR45.1
#=GS A0A841Q263_9BACI/32-198  AC A0A841Q263.1
#=GS A0A1Y4S557_9FIRM/36-210  AC A0A1Y4S557.1
#=GS A0A1Y3XF21_9FIRM/36-220  AC A0A1Y3XF21.1
#=GS A0A1Y3XJ38_9FIRM/36-211  AC A0A1Y3XJ38.1
#=GS A0A1Y3XF22_9FIRM/36-205  AC A0A1Y3XF22.1
#=GS A0A428J6N8_9BACI/32-188  AC A0A428J6N8.1
#=GS A0A1Y4WJ17_9FIRM/55-214  AC A0A1Y4WJ17.1
#=GS G9YSH8_FLAPL/36-145      AC G9YSH8.1
#=GS A0A1Y4WK08_9FIRM/53-227  AC A0A1Y4WK08.1
#=GS A0A1Y4WI68_9FIRM/36-212  AC A0A1Y4WI68.1
#=GS A6NQ07_9FIRM/36-211      AC A6NQ07.1
#=GS A0A1R1DXN9_9BACL/32-193  AC A0A1R1DXN9.1
G9YSI2_FLAPL/36-214                 .............PFLTARGALAATQERYAFGPGEVIAR..FSPQ..........QE.GMPPL....RYYIVRDGDWF.AWCSV...EG.D....GLFWRP.GALT.AACPDGEAPLAILAS....PTfGGTSP....ELV.V....VS...SDPDIAAVELDYLVKSAIIDTVVYVHVEMARQEPLEDS.CFYFSLEDAYSRLFYETPSTVF...RVRYYDADGKLLYESPYPARWLE.Y............
A0A6N8FKR4_9BACI/35-197             ...spikaheqse-------------RTFYYGPSEIIEE..FDF-..........--.--GDI....RIYLAKYKDWF.SANTV..tKY.A....GVFWQPgSHVN.GFKIEEEEDISYTWS....SS.KINEE....LML.MkyygIV...TNPKIDKVELDVTVGYVWDEEVPEDDIETLSE-SLDDHrMFLFH------WNENEDNYLAL...ALRGLDEKGNIIYEE--------.-nl..........
A0A433Y885_9BACL/31-194             ....gsltptkah---------ELSERSYHYGPSKIVKV..VPF-..........--.GGNT-....TVYLGVYKEWF.SSDTV...IK.R....GLGWHPgGGVG.GVWIDSSKPLTYSWSvserDK.KLTLA....QFY.G....YV...SDPEITTVVLY--TETDSVDNKEARTLSTMSQEINEDR.MFLFIWNDKDLNSH----WKS-...-IQGLDQEGKVVYE---------.-ekf.........
G9YSI0_FLAPL/35-207                 .............PYFTRSQALWALQKANFFEGGRVVAW..SSP-..........PE.DRDT-....AYAVLRWDGWY.AVGTL...RR.A....GPFWEP.VRFN.AVQPDDALPITLLFE....DA.GIAHS....FLC.V....LS...SDPQIVTMELDYVAGFSETSSSP-QQLRTLRREAVE-H.CFLFP-CDGSAWVPVDDPFQSI...RLRGYDTAGNLVYESPVPSLWAN.Y............
A0A1H1DR45_9BACI/37-197             ...ikaheqsert---------------YYYGPSKVVED..----..........-I.DLGDV....HIYLGKYKDWFsANMVV...RH.A....GIFWRP.GSGVgGDEIKQDQDITHSWA....GS.TIKED....YML.MrfygIV...TNPEIAEVELDVVEGYDRAEKVSEDQIRTFSYELENHR.MFLFH------WNEQKHEYRRL...SLRGIDESGNVVYEK--------.-dl..........
A0A841Q263_9BACI/32-198             yhlspleahqqse-------------RTFYYGPSEVVEE..VEI-..........--.--GDA....RIYLGTYKNWFsANMVL...KH.K....GIFWAP.GSGVgGHEINKSKDLSYSWS....GS.SIDKD....TML.MrfygIV...TNPEIVDVELDLVEATLNSDSYQKDQINTLSFHLKNHR.MFLFH------WNMQENNYRQV...AIRGLDENGEVVYEEEWP-----.-............
A0A1Y4S557_9FIRM/36-210             .............PCFTRNQAFSALEDRNFYGNGQVLRT..----..........LE.GNYGH....QYRITRAGDCY.AWEQVwpvLF.S....RILWQP.GQME.VISDDPEAPLVALPV....DP.DFLPG....VVA.V....VS...HDASIVTVEVTYPALCRPGGPEGWQKVTISSADCVN-N.CFLLRAPEEEAAQLDHQAMDAL...SLTGYDAAGAVVWRSPQPD----.-wsly........
A0A1Y3XF21_9FIRM/36-220             .............PVLTANQALEATQARYFFGPGEVISTqdYSINhlvsrlfvrsSD.RVGSY...dRYYILRNGDWY.AWCGI...NR.R...lLLFWQT.GELG.AVENDPDLPLVPLI-....-V.SNQYN....GIVlV....IS...NDPEIT--QVEITFPISAETKQGYTLLSASQTQSTE-N.CFLIPYTSGPGFVFP----EDL...QVKGYDAAGALRYQSPIPESWAT.-hy..........
A0A1Y3XJ38_9FIRM/36-211             .............PILTAEQALEATQDRYFFGPGEVITTldYSREa........nKV.KIGQY...dRYYILRHGDWY.AWCGV...NH.Y....GLFWQT.GGLD.AVENDPDLPLVPLV-....VS.DWNSG....AVL.V....IS...NDPEITQ--VEITFPISAETKQGYTLLSASQTESTE-N.CFLIPYTSGPGFFFP----EDL...QVKGYDAAGALLYQSPKPESWAT.-ry..........
A0A1Y3XF22_9FIRM/36-205             .............PMLTAEQALRATQTRYYWEDGQVVAD..LGSG..........--.--PLY...dRQYLLRMGNWY.AWCGL...SR.E....GLLWDS.GTLV.SLYRDPEQPLSAV--....-T.PYSWG....AVL.V....LA...GDPDIVQVEVEYPVLVSESDAGRVYGLNTLRQGPVADG.CFWFQLTGNLLPAYY---MDRI...RLRGYDADGRLIYQSPEPESWTT.-ry..........
A0A428J6N8_9BACI/32-188             .lsplaaheqser--------------TYHYGPSNIVES..----..........-I.DVGDV....RLYMGTYKEWF.SVNSV...EKhA....GVFWRPgSHVG.GTEIDKNQAISYSWS....GS.TINDDlmlmKIY.G....VV...TNPNIVEVQLDVMEGSG-------NPVQTLSYPLKDHR.MFLFY------WNELENPYKWL...FLRGVDKTGNTVYE---------.-hel.........
A0A1Y4WJ17_9FIRM/55-214             .............PFLTERQALSATQTRYLYGPGAVLAR..VEN-..........--.--DTF....VDCILQDGSCY.AVCTL...PR.K....GLFWGQ.GTLD.AVVNDPSLPLVPL--....--.-PRRD....SLL.V....VV...NDPDIAEVEVLYYAQYSG---GF-H--TLRQTEPLADK.CYLFYRPAGQSNYHFD--DDGF...LLRGYDRAGNLIYESEAPGHWAE.-w...........
G9YSH8_FLAPL/36-145                 .............PCFTHQAALERLQSRFHFGPVDAAQW..YPE-..........--.---E-....AIYALRYDRWY.AVCSL...ER.QpfflGHTWRPyARGL.IAAPVEDAPLSVC--....--.GIHYD....LFF.G....LC...SDPAIESVRI----------------------------.----------------------...-----------------------.-tctgdggthtae
A0A1Y4WK08_9FIRM/53-227             .............PFLTARGALAATQARYGFGPGEVVTR..IKD-..........-S.RYST-....YRYIVRCGDWY.ASCGV...YQ.R....GPLWRS.GQLM.AVESRPETPLVSLII....QE.QVDNS....TIL.V....VS...NDPEIASVEVRFPVIYEGVAGWK--LFSVRSSQAVE-N.CFFVTYDETAHTEVSDFPFTQIghhRLRGYDRDGSLIYEAPVPEAWAA.Y............
A0A1Y4WI68_9FIRM/36-212             .............PVFTARQALAATQARYFFGPGEVIAA..LDNP..........QEwDAGRFgpsdRYYILRWGDWY.AWCGI...SR.S....GPFWRT.GSLG.AVENDPSLPLIPLVV....D-.EYSYG....SVL.V....VC...NDPGIARVELVFPVSSPETDSGC--TLLSASGGQTAEG.CFLIPYYI-PSGSFL--SSDAL...QVKGYDAAGALRYESPVPERWAG.Y............
A6NQ07_9FIRM/36-211                 .............PIPTIGAALRAAQQEILFGPGEIVAE..FTRDe........lPE.DAPDF...dRAYVLQWEGRY.ALFTF...SY.C....DLSWHQwARPV.VLEPSPNLPLTAA--....--.AGSFP....KCV.L....IY...SQTDSIT-RVEAVHPCLDYERRDVQPLTTSSALALDNQ.LFFLPLSQSFDSSSV--VLDAV...QLRGYDASGALVYESPVPGTWAEgY............
A0A1R1DXN9_9BACL/32-193             ............s--FTAQGAHELSERSYHYGPSKVVRK..VQV-..........--.DQDT-....VVFLGTYKQWF.SADTV...TW.S....HFKWHPsGGVA.GVPKNPEKPLAYSWD....MKsTGSDG....GLA.K....FYgyvNDPDIVTVELDVVMEDRGSNTAT---SGSERQRISDDR.MFLFVWKTE----GR--DFSWQ...SIKGLDREGKVRYE---------.-hkl.........
#=GC seq_cons                       .............PhhTtptAhtthpppYaaGPucVlpp..hp...............t.ssh....phYlh+atcWa.Ahssl...p+.p....GlhWcs.Gpls.ulp.-sstPLshhh......t.shs.s....tll.s....ls...sDP-IspVEl-hsh.hst.spht.p.lpshptp.hppp.hFLh.h.tt..h.h....hctl...pl+GhDtsGsllYEp..P...................
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