#=GF ID   DUF5088
#=GF AC   PF17008.9
#=GF DE   Domain of unknown function (DUF5088)
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   c_1838 - Hurt RP, Nakjang S
#=GF GA   29.40 29.40;
#=GF TC   29.40 30.60;
#=GF NC   28.10 29.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR031540;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of microsporidial sequences of unknown
#=GF CC   function.
#=GF SQ   29
#=GS I3EHQ1_NEMP3/220-417      AC I3EHQ1.1
#=GS A0A059EST8_9MICR/182-302  AC A0A059EST8.1
#=GS A0A059F1E5_9MICR/266-386  AC A0A059F1E5.1
#=GS A0A4Q9LDB0_9MICR/165-380  AC A0A4Q9LDB0.1
#=GS A0A4Q9LEG5_9MICR/165-380  AC A0A4Q9LEG5.1
#=GS A0A059F1E5_9MICR/136-241  AC A0A059F1E5.1
#=GS J9D506_EDHAE/483-618      AC J9D506.1
#=GS J9D506_EDHAE/351-465      AC J9D506.1
#=GS L2GSQ0_VAVCU/358-473      AC L2GSQ0.1
#=GS A0A059EST8_9MICR/52-157   AC A0A059EST8.1
#=GS H8ZDW6_NEMS1/218-415      AC H8ZDW6.1
#=GS L7JXM0_TRAHO/180-290      AC L7JXM0.1
#=GS R0MFF2_NOSB1/140-298      AC R0MFF2.1
#=GS A0A437AHR3_9MICR/265-383  AC A0A437AHR3.1
#=GS T0L8G1_9MICR/1-145        AC T0L8G1.1
#=GS A0A1Y1S8G5_9MICR/176-364  AC A0A1Y1S8G5.1
#=GS A0A437AHR3_9MICR/134-235  AC A0A437AHR3.1
#=GS L2GSQ0_VAVCU/183-295      AC L2GSQ0.1
#=GS C4V8A1_NOSCE/121-302      AC C4V8A1.1
#=GS A0A6A5CAG3_NAEFO/241-448  AC A0A6A5CAG3.1
#=GS A9CS98_ENTBH/165-350      AC A9CS98.1
#=GS A0A177EKF1_9MICR/199-407  AC A0A177EKF1.1
#=GS L7JXR1_TRAHO/9-101        AC L7JXR1.1
#=GS Q8SV46_ENCCU/186-369      AC Q8SV46.1
#=GS A0A1W0E430_9MICR/173-361  AC A0A1W0E430.1
#=GS L2GQ94_VITCO/163-345      AC L2GQ94.1
#=GS A0A0F9WII7_9MICR/121-302  AC A0A0F9WII7.1
#=GS A0A1X0QAZ1_9MICR/145-338  AC A0A1X0QAZ1.1
#=GS A0A4Q9LS00_9MICR/165-380  AC A0A4Q9LS00.1
I3EHQ1_NEMP3/220-417                 ................................GRVILKSKLFTFSSGGSFp...lFFSFII...L...TVAGL...VKVYVWK.LAVRKFF.CVKEGDYVVIRGFKIKRRPGA...LLVADR.tNTDSDTKYACI....PEISVNltg...............ptgYIMEIDSLP...DLPDVSEDs....eFTTVVGRVEYISSILRYRe...........ckSRLKFRD.YVYLKI........SGIVVMLLANG.ADNLLD.IQIGKIVEIRHLRKGEIGSFEFYISSLYTQF....................
A0A059EST8_9MICR/182-302             ..................kennseeseyklri------------------.....------...-...-----...-------.-------.---------------------...------..-----------....------.....................--KRIKRDI...KLPTTCI-......NNTVTGTITYLSTLKKLRtswkdynikslkeqRNLKTFE.YFLMRI........NDKPLILFNTS.QEEFYK.LKTGKQILIENLRSYQRGKLTIYMSSIYTHI....................
A0A059F1E5_9MICR/266-386             ..................kennseeseyklri------------------.....------...-...-----...-------.-------.---------------------...------..-----------....------.....................--KRIKRDI...KLPTTCI-......NNTVTGTITYLSTLKKLRtswkdynikslkeqRNLKTFE.YFLMRI........NDKPLILFNTS.QEEFYK.LKTGKQILVENLRSYQRGKLNIYMSSIYTHI....................
A0A4Q9LDB0_9MICR/165-380             ................................GKVLYKTRIN------NN.....FFVLIF...S...SSDCL...LKIFCWN.--L-KFS.SIKVNDVIVIIKYKNCENQGF..hSNKIVY..NEFNELNYFNC....SEIKTVkdtkiylaqdveqkndfdkfsNLYKYKFKP...VDSFLEIHsk..lpFYSLKGIVTYLSILLRKRnkyg......cyleRGGKIYE.YFLMRIcdttksngMVYSVVVFICS.-TVFYD.VKVGDEIVLINTRKIERGNEFIYCSSIYTD-m...................
A0A4Q9LEG5_9MICR/165-380             ................................GKVLYKTRIN------NN.....FFVLIF...S...SSDCL...LKIFCWN.--L-KFS.SIKVNDVIVIIKYKNCENQGF..hSNKIVY..NEFNELNYFNC....SEIKTVkdtkiylaqdveqkndfdkfsNLYKYKFKP...VDSFLEIHsk..lpFYSLKGIVTYLSILLRKRnkyg......cyleRGGKIYE.YFLMRIcdttksngMVYSVVVFICS.-TVFYD.VKVGDEIVLINTRKIERGNEFIYCSSIYTD-m...................
A0A059F1E5_9MICR/136-241             ..............................ct--VLMKSRLHYKPSC-SF.....YFQAIV...E...TESDL...CKIDFWG.SAAKLHS.SIELSSQIGIIKDKKIKKISK...PE-LLY..NSFYEEMYFNL....DCYKVS.....................---------...--------......------------------..............-------.------........-----------.------.-------------------------------dpkkvfmindefyfdknglt
J9D506_EDHAE/483-618                 ......................styeidihtd------------------.....------...-...-----...-------.-------.---------------------...------..NSNKEQTHAAInyktHEISTK.....................TVNIMD---...--TKYHSD.....fYESITGKIICLSVLIRKRnkls......dflyEKDRVLE.YYNIKLvd...efnRIRFVQLFNNS.SLIFQE.INTDIWIKLDNLWKLTRGNFAFFVSSCFTEI....................
J9D506_EDHAE/351-465                 ................................GKITHKSRVFVYDRVSDVp...vYFFVIL...S...SGFKN...AAVFFWE.QNVHKYYmQIQRGDIVIFNRYRVVYKP-L...GSFVHI..NTYAENFLFNC....VEVHLNe..................nsELFKITNDC...MSNK----......------------------..............-------.------........-----------.------.-------------------------------finstnscd...........
L2GSQ0_VAVCU/358-473                 kteeksappldafvkvqlslspfdtptmsfpf------------------.....------...-...-----...-------.-------.---------------------...------..-----------....------.....................---------...--------......LHPIEGRINYISILLRKRkseg......tyflINDKIEE.FYLMRI........GEAIIYMFNTS.EEVFYE.LDARDYVILENMRIID---TNVYVSTVFTTI....................
A0A059EST8_9MICR/52-157              ..............................ct--VLMKSRLHYKPSC-SF.....YFQAIV...E...TESDL...CKIDFWG.SAAKLHS.SIELSSQIGIIKDKKIKKISK...PE-LLY..NSFYEEMYFNL....DCYKVS.....................---------...--------......------------------..............-------.------........-----------.------.-------------------------------dpkkvfmindefyfdknglt
H8ZDW6_NEMS1/218-415                 ................................GQVILKSRLFTFSSGGSLp...lFFSFIL...L...TSAGL...VKVYVWK.LAVRKFF.CIKEGDYIFIRGFKIKRRPGA...LLIADR.tNTDSDTKYASI....PEISVNlte...............ptgHIMEMEMLH...GLPKVPYDp....eFTTVIGIVEYVSSLFRYRe...........gkARMKFRE.YVYLKV........SGIIIKLLAND.TESIID.IKTGTSIEVRHLRKGTIGPFEFYISSLYTQF....................
L7JXM0_TRAHO/180-290                 ................................AKIVLKSRIIAYNHGSFP.....FYQVLVvvdL...TENKL...VTVVLWN.RSVYKYC.NLQHNDIVIIPRCRKKKRYYN...NGVMVY..NSYSDVWMFDC....EEFSVNg..................ndDI-------...--------......------------------..............-------.------........-----------.------.-------------------------------cvcdirkvxxxxxxx.....
R0MFF2_NOSB1/140-298                 ................................GKVVYKTRINYTNLKY--.....YFFMIL...Q...INNEL...LKVFIWR.ENI-KYS.ALKVGDIVGLQKYRVSKGYQG...LSCLDY..NRFSEAAYFDT....KEVTGI.....................ELVKFDTEI...DCKAKSF-......LPSIEGFISYKSVLTRRN..............-HGGLDE.YYLLVV........NNEPVVLFFNS.DLKFYE.IEAGNYIKIT---------------------i...................
A0A437AHR3_9MICR/265-383             .........nnsedseyklrikrtkrdlklpv------------------.....------...-...-----...-------.-------.---------------------...------..-----------....------.....................---------...-------Ts....lSNTITGTITYISTLKKVRtsfkdyniesvteqKGSKVYE.YFLLRV........NDTCVILFNNS.QEQFYR.LKSGKQXLLENLRCYKRGNTDLFMSSIYTTI....................
T0L8G1_9MICR/1-145                   ................................------------------.....------...-...-----...---MIWK.ENF-KFS.YFEIGDEVEIFKYRQSKGFQN...HGHIEI..NEFSELVYFNI....DEITIS.....................EMTLVKKNN...DEKLKNNT......-SYEEKHIDLLKNIN---..............--HTVKGvIYYTNV........ENKKVILFYNS.DLSFYN.IEAGNIIEIKNLRKIQRSGYDLYISTIYTQF....................
A0A1Y1S8G5_9MICR/176-364             ................................GRIVQKTRINIYPHAYNP.....FCFAIV...T...ANNVF...VKLVFWK.EHLTLYS.SLQVGDSVYVKSFSQRSASNV...PDKIIY..GTFTESCYFKV....KEITPK.....................EVFKVFPRR...PIGHREIR.....lLDTIRGRVVYSSVTLRQT..............TKHVYQE.YLLLRMed...edgNVFSVLLQNNS.QEDFYR.LR-NRVVELCEMRRIHRGGAELYISSIYTRI....................
A0A437AHR3_9MICR/134-235             ..............................ct--VVMKSRLHHRPNNI-F.....YFQAIV...E...TETSF...CKVDFWG.SAAKLHS.SLELSSQIAITKSKK-VVKNF...SSELLY..NTFYEEMYFDF....NCYKV-.....................---------...--------......------------------..............-------.------........-----------.------.-------------------------------ndsksvllvgddffcdk...
L2GSQ0_VAVCU/183-295                 ................................AKIIFKSRILAYKHTSFP.....FYQILV...VldlIEDKL...VTVVLWN.RSVYKYC.NLQRNDTVVIPRCRKKNRYYN...NGVIVY..NSYSDVWMFDC....EEFSVNgr................devYICDIEGVN...DEDS----......------------------..............-------.------........-----------.------.-------------------------------adgs................
C4V8A1_NOSCE/121-302                 ................................GKIIYKTRINVTNTSQ--.....YLFFIL...E...TDNEL...FKIIIWK.ENL-KYS.SLNVGDFIGITKFRAGKGYPP...QGHIEH..NEFSEMGFFNV....KELTVH.....................ELFKLPGLN...TKETFKNIe....hFKNISGFIKYRSVLNRKS..............-NHGYSE.YYLLMV........EDVKVVLFYNS.DLNFYN.IEAGNRIEITNLRQITRQNATFYISTIFTQF....................
A0A6A5CAG3_NAEFO/241-448             ................................ARIYKKSKIRYYGKTYEEka.cpMFYTLL...I...TDKSTpkgVPVTIWNdLALHSYA.ELNIGDVIIVDEYRVKQFYDSgvfTTKFKHeiSINSSKTQQPI....QKIDPKqleavk........efaplsfP-----VTT...IHEIVELSls..daIVHVLGAVVNIGPYLRER..............LHSQFSR.YKYLTLvdp..ssdQMMSVKVYTNS.RKNLLDsVHVGQVIFISDLCVKQI--------------stsied..............
A9CS98_ENTBH/165-350                 ................................GQIQQKTRINLYPGVYNP.....FFFIIV...S...YDIGI...AKIVFWK.ENILKYS.SLDVGDTIYVKTFRKKKKTEL...CSKLTY..NTFTETMYFDV....DEIVSN.....................EIYKVSISL...NKDIFRI-......FDTIQGHVIYSSVILKNN..............YNGMYHE.YQFLKLlh....kdTIKYVVLFNNS.QKEFYK.LR-NKNIILYEMRYIKRGEINLYISTIYTRI....................
A0A177EKF1_9MICR/199-407             ................................GRVLLKSKLFPLKDAFGAthtpfVFSFVF...E...TSQGI...AKVYVWG.TCVWKFF.CLREGDPVIIRGFKVKRSKGS...LALGDR.tISDTDTRYATI....PEITINsaep.............tgeiEILDESLLDeivYDDAFTDK.....eFATVAGTVEYVSSLLRWKeaa........shaKTQRVRE.FVYLRV........AGTVIKLFSNGpTEDILG.IHAGQYLEVRHLRKCTIGAVTFYISSLYTQF....................
L7JXR1_TRAHO/9-101                   .......................dvlslsfsf------------------.....------...-...-----...-------.-------.---------------------...------..-----------....------.....................---------...--------......LHSIEGRINYISILLRKRkaeg......tfflVNDKIEE.FYLLRI........GEMIVYLFNTS.EKVFYE.LDAYDQVTLGNMRMID---TNVYVSTIFTNI....................
Q8SV46_ENCCU/186-369                 ................................GRVGYKTRMSSVTYTRKYp...yYFLILL...T...SSRHL...LKVFVWG.EDL-PYS.SMRVGDAIGLAKYREKPVIEG...PPVVEH..NRFTEARYFRC....KEVSAK.....................EIFRIELEK...YEEMPEPI......FTEAFGKVEYLSVLNRRS..............-AGYLEE.YYLIRM........GRCRVLLFYNS.SKEFHE.IEVGKYVRITNLRASKCRRSEFHISTIYTQI....................
A0A1W0E430_9MICR/173-361             ................................AKIQQKTRINTIPNKFNP.....FFFIIA...S...SSNIL...VKIVFWK.EQIAKYS.ELNVGDIVLINSFKKYNSPFK...VEKLIY..NTFTESVYFSC....QAIRAN.....................TLYKVESDF...FHKNNKIIr....lFKTIHGDVVYSSMIFRHN..............HANSFLQ.FKYIKLnc....egEVIYVVLFYNS.QKEFYN.LD-KNSIILHEMRRIDRGGLVFYVSTIYTQI....................
L2GQ94_VITCO/163-345                 ................................AKIIQKTRISTYPTSFNP.....FFFAIV...S...SGDVM...VKIVFWI.ESLKQYS.SLKVGDIIMVKEYRKKKKWSA...FDKIDI..NTFTESVYFDV....EEITAK.....................ELVKIKFNK...KSISRSI-......FETVEGKIEYLSVLMRYN..............CNDTLME.YVLMHV........SGKKVVLFYNS.DTEFYK.INVGIHIVIAELRKMERAGFEFYVSTIYTQF....................
A0A0F9WII7_9MICR/121-302             ................................GKIIYKTRINVTNTSQ--.....YLFFIL...E...TDNEL...FKIIIWK.ENL-KYS.SLNVGDFIGITKFRAGKGYPP...QGHIEH..NEFSEMGFFNV....KELTVH.....................ELFKLPGLN...TKETFKNIe....hFKNISGFIKYRSVLNRKS..............-NHGYSE.YYLLMV........EDVKVVLFYNS.DLNFYN.IEAGNRIEITNLRQITRQNATFYISTIFTQF....................
A0A1X0QAZ1_9MICR/145-338             ...............................c-RVVKKTRISSVTNNFNP.....FFFVIG...H...SNNVF...IKIIFWL.ENLAAYS.TLKVGDLIYVSDFKKKIKTPS...PSKLIF..NNLTESFYFDL....DEVTVK.....................TLYKLKLEP...EITIPIAYnsygtpFIKIEGNIIYVSVLLKYR..............VAETILE.YYLIKIkd...engNIKQVVLFNNS.DDLFYQ.IK-GGYIILEDMRKVERGSFTYYLSTLYTQI....................
A0A4Q9LS00_9MICR/165-380             ................................GKVLYKTRIN------NN.....FFVLIF...S...SSDCL...LKIFCWN.--L-KFS.SIKVNDVIVIIKYKNCENQGF..hSNKIVY..NEFNELNYFNC....SEIKTVkdtkiylaqdveqkndfdkfsNLYKYKFKP...VDSFLEIHsk..lpFYSLKGIVTYLSILLRKRnkyg......cyleRGGKIYE.YFLMRIcdttksngMVYSVVVFICS.-TVFYD.VKVGDEIVLINTRKIERGNEFIYCSSIYTD-m...................
#=GC seq_cons                        ................................uplhhKoRl..h...........aa.hlh.......oppth...hKlhhWt..sl.tas.slphuD.lhl.pa+.tpt.......shl.h..NpasE.haFsh....pElpsp.....................plhchp.........h.p........h.slpGhl.YhShlh+hp...............ttth.E.Yhhh+l........t.h.VhLF.sS.pp.Fap.lcssp.l.ltphRthphtt..hYhSolaTph....................
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