#=GF ID   DUF5099
#=GF AC   PF17025.9
#=GF DE   Domain of unknown function (DUF5099)
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   c_2028 - Hirt RP, Nakjang S
#=GF GA   27.00 27.00;
#=GF TC   27.20 33.10;
#=GF NC   26.20 25.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   24259309
#=GF RT   Reduction and expansion in microsporidian genome evolution: new
#=GF RT   insights from comparative genomics.
#=GF RA   Nakjang S, Williams TA, Heinz E, Watson AK, Foster PG, Sendra
#=GF RA   KM, Heaps SE, Hirt RP, Martin Embley T;
#=GF RL   Genome Biol Evol. 2013;5:2285-2303.
#=GF DR   INTERPRO; IPR031503;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of microsporidia-specific sequences of unknown
#=GF CC   function.
#=GF SQ   27
#=GS L2GUR2_VAVCU/19-125      AC L2GUR2.1
#=GS S7W942_SPRLO/14-115      AC S7W942.1
#=GS H8Z9J2_NEMS1/34-161      AC H8Z9J2.1
#=GS R0KYJ4_NOSB1/64-171      AC R0KYJ4.1
#=GS A0A1W0E960_9MICR/2-90    AC A0A1W0E960.1
#=GS A0A1X0Q9H1_9MICR/7-93    AC A0A1X0Q9H1.1
#=GS A0A4Q9LCP5_9MICR/18-131  AC A0A4Q9LCP5.1
#=GS B7XNW4_ENTBH/4-85        AC B7XNW4.1
#=GS A0A059EXM3_9MICR/6-108   AC A0A059EXM3.1
#=GS T0LCR9_9MICR/6-98        AC T0LCR9.1
#=GS A0A059EM26_9MICR/3-68    AC A0A059EM26.1
#=GS B7XKR1_ENTBH/4-95        AC B7XKR1.1
#=GS B7XM64_ENTBH/9-100       AC B7XM64.1
#=GS Q8SUB2_ENCCU/17-107      AC Q8SUB2.1
#=GS B7XLV1_ENTBH/6-77        AC B7XLV1.1
#=GS A0A1Y1S5T0_9MICR/2-89    AC A0A1Y1S5T0.1
#=GS L7JZ01_TRAHO/19-125      AC L7JZ01.1
#=GS A0A437AP04_9MICR/9-111   AC A0A437AP04.1
#=GS A0A0F9WQC1_9MICR/6-98    AC A0A0F9WQC1.1
#=GS A0A0R0LXE6_9MICR/17-123  AC A0A0R0LXE6.1
#=GS B7XRE2_ENTBH/4-94        AC B7XRE2.1
#=GS A0A0B2UL76_9MICR/17-109  AC A0A0B2UL76.1
#=GS C4VBK8_NOSCE/6-98        AC C4VBK8.1
#=GS J9D2N9_EDHAE/18-126      AC J9D2N9.1
#=GS A0A177EC39_9MICR/38-170  AC A0A177EC39.1
#=GS A0A4Q9LF44_9MICR/18-131  AC A0A4Q9LF44.1
#=GS I3EK17_NEMP3/34-161      AC I3EK17.1
L2GUR2_VAVCU/19-125                 ............................KKPDIIFIVDAYK.DVPPHDIGELQS.KYGIK................kILI.L.KRDD.....LDTFHA.QE...PLDI...---QSLPDLIIYCNNKLEFKLREPEILYKAEIVFSR.F.G.FGERLFVEALDHYSSCVINSG..
S7W942_SPRLO/14-115                 ............................KLPSYFLIVNNKA.KLSNTDIIRVKElTNGIV.................---.-.----.....-DRVEI.IN...EMDS..nEDLDGHPDLILLLNDVLYFHLKNPLLLYKAEIFIYK.K.N.FCMDAVYKALSHYSECKINNG..
H8Z9J2_NEMS1/34-161                 ............................KKAAWVLVINMYS.PVQSSVLDQLGD.KYGIKltvqendqdtfqnnhkkFCK.S.IGEY.....TEKVPY.VD...IMDFv.sSNKSMFPDIVILCSDKTIFKTTSPFLLYSAELLHTR.K.D.FSEDALIRALQHYADCEIRNG..
R0KYJ4_NOSB1/64-171                 ............................KIPKNILIIDKINpEIDKDLKKKIISfSKDIN.................-IF.F.CDCI.....KDSFLC.--...EICI...KNKEMKYDLVFLCNYSLFFNLKSPLNICESEIIFNR.K.R.IDFGIFMKGIEYYSECEIRNG..
A0A1W0E960_9MICR/2-90               ...................andlknili-------------.------------.-----.................-VA.K.NAHQ.....FENYVIpGV...NVDV...IGRDVKYDLVIYTDIVFSLNLKHCKSISDAEIWFER.K.EeMTNTIISNAIDHYKKCEKR--lg
A0A1X0Q9H1_9MICR/7-93               ........klpkrtlflsyqsnvykpnc-------------.------------.-----.................---.-.----.....------.SL...NIDY..kPKKGIIYDLIVYVEWKFRMNIKYPECVSDAEIYFVRgE.S.ITEKIFLDALKHYNGADIRKG..
A0A4Q9LCP5_9MICR/18-131             ............................KVPKYVLIIDNYN.TFTYDLLLKMKC.ILQIE.................KLK.VlVDKE.....KNEFDL.ENskyNINY..fYDNTLLPDMIILCNDIFSFKIENPLLLSRAEIWFSR.Y.K.LNENTFYQAYWHYSDCEIRNG..
B7XNW4_ENTBH/4-85                   isiktkypkkvllvgnivgqilppvpdi-------------.------------.-----.................---.-.----.....------.--...QIDN...QCGNTHYDLIVYVDLVFQLDIKYPVAISDAEIWFERgT.S.IDQYVFQRAL-----------p.
A0A059EXM3_9MICR/6-108              ............................KIPKFVLLIDPHN.KAPE-IINSF--.-CKIK.................--K.L.SYEY.....DTDFYF.MD...RNCN..kICNCQEPDMIILIDYVLHFNIGCFKLLRNAEIFF-R.N.E.WYDNLIEDALIFYSECEIRNG..
T0LCR9_9MICR/6-98                   ............................KLPSQVLVLDYLS.TVSANLIKQIQSyNKNIN.................---.-.----.....------.--...-VDF...LEHDKKYDLVFLCNYVFEFDLNFYKTVSSAEIIFRR.N.K.FTFNIFMEGLKHYSECQIRNG..
A0A059EM26_9MICR/3-68               ................fmdrncnkicnc-------------.------------.-----.................---.-.----.....------.--...----...----QEPDMIILIDYVLHFNIGCFKLLRNAEIFF-R.N.E.WYDNLIEDALIFYSECEIRNG..
B7XKR1_ENTBH/4-95                   isiktkypkkvllvgnivgqilppvpdi-------------.------------.-----.................---.-.----.....------.--...QIDN...QCGNTHYDLIVYVDLVFQLDIKYPVAISDAEIWFERgT.S.IDQYVFQRALAHYEVCEQRRG..
B7XM64_ENTBH/9-100                  flknqnspkkvfffgkifgkilppvpdf-------------.------------.-----.................---.-.----.....------.--...QIDI...QWGNPHYDLIVYVDLVFQLDIKYPVAISDAEIWFERgT.S.IDQYVFQRALAHYEVCEQRRG..
Q8SUB2_ENCCU/17-107                 ............................KIPKTTLIVDGYG.TITEEEKRKIQG.-MKMN.................---.-.----.....------.--...-IDF...EERTTHYSLVILCNTTLRFNLANPLTLAECEIWFTR.K.A.FSSRVFMDALIHYSECEIKNG..
B7XLV1_ENTBH/6-77                   ....................rfcpgsgl-------------.------------.-----.................---.-.----.....------.--...QIDN...QCGNTHYDLIVYVDLVFQLDIKYPVAISDAEIWFERgT.S.IDQYVFQRALAHYEVCEQRRG..
A0A1Y1S5T0_9MICR/2-89               ......................nnkqpk-------------.------------.-NVLV.................IAK.V.IDCD.....LENYPI.--...AIDT...VPKDKEYDLLVYVDYRFNLDMIYPYSIANAEIWYER.GdT.VDCGVMERAFEHYRTCEIREG..
L7JZ01_TRAHO/19-125                 ............................KKPNLIFIINAYQ.NISLDEIQRLRD.KYGIE................kIVG.L.QRDD.....FDTFYT.QE...QLDR...---NNLPDLIIYCNIKLEFKLRQPEILYKAEIVFSR.F.G.FSEGLFVKALDHFSKCIINNG..
A0A437AP04_9MICR/9-111              ............................KIPDFILVIDPHN.KSKLKKINKIKL.K-KLS.................---.-.-KTL.....EDETHF.LD...KQCN..kLCDCEEPNLIILIDHVLHFDLGCFKLIRQAEIFF-R.T.E.WYDNILEDALKFYSECEIKNG..
A0A0F9WQC1_9MICR/6-98               ............................KTPKKILILNNIG.TLSQDLKIKIRK.-----.................---.-.----.....---FLP.NS...LIDF...EENDIQYDLVFLLDYIFKFNLQYYKPISVAEIIFKR.Q.T.FDFKIFEEGLRHYSDCEIRNG..
A0A0R0LXE6_9MICR/17-123             ............................KLPKIVFIISSYD.DISQETLFFLKK.KYNIA.................QITsL.EQNE.....AGKFFY.NG...HLDI...---KDVPDLIILCHDKLEFHLEQPEILYKAEIVHSR.C.C.FSESVFENALSHFSDALINNG..
B7XRE2_ENTBH/4-94                   isiktkypkkvllvgnivgqilppvpdi-------------.------------.-----.................---.-.----.....------.--...QIDN...QCGNTHYDLIVYVDLVFQLDIKYPVAISDAEIWFERgT.S.IDQYVFQRALAHYEVCEQ---rr
A0A0B2UL76_9MICR/17-109             ............................KYPKTILVVDMYG.TTTNLMKDLVRC.--QVN.................---.-.----.....------.GT...QIDF...EETQTHYSLVIVCNNRFKFRVDNPLSLVDCEIWFSR.K.A.FSLDVFIDALHHYSECEIRNG..
C4VBK8_NOSCE/6-98                   ............................KTPKKILILNNIG.TLSQDLKIKIRK.-----.................---.-.----.....---FLP.NS...LIDF...EENDIQYDLVFLLDYIFKFNLQYYKPISVAEIIFKR.Q.T.FDFKIFEEGLRHYSDCEIRNG..
J9D2N9_EDHAE/18-126                 ............................KLPKYVLVISRYS.EIKANLIKSLKL.KYKIE.................DVK.I.LGDK.....DDEYTI.KN...RINM...TKGGKYPDLIILCSDVLMFYLQDPLILYKAEIWHER.R.D.FCESTFVYALRHYDECEIRNG..
A0A177EC39_9MICR/38-170             ...........................r-LPRSVLIINTYA.PIGSDLLSSLQN.RYALKelkesvkt.dyqeeyqkFVR.A.VDENeppveKTRKEA.YE...RLCRfieSKNQLFPDLVILCSEAAKLATNQPFLLYQAEIHHSR.E.E.FSESVLIKALGHYSTCEQRNG..
A0A4Q9LF44_9MICR/18-131             ............................KVPKYVLIIDNYN.TFTYDLLLKMKC.ILQIE.................KLK.VlVDKE.....KNEFDL.ENskyNINY..fYDNTLLPDMIILCNDIFSFKIENPLLLSRAEIWFSR.Y.K.LNENTFYQAYWHYSDCEIRNG..
I3EK17_NEMP3/34-161                 ............................KRPKWVFIINMYG.CVPKETIEKLGK.THDIKltvqetdqdtfqsnhakFCK.M.IGES.....KTKVPY.NE...IVEFi.sKNKSVFPDIVILCSDTTVFKTNSPFLLYSAEVLHFR.K.N.FSSDVLESALNHYSLCEVRNG..
#=GC seq_cons                       ............................KhPp.hhlls.ht..h....h..h......h....................................h........plDh....ptshp.DLlllsshhhpFclppPhhltcAEIaFpR.p.s.hspslF.cALtHYScCEIRNG..
//