#=GF ID   DUF5100
#=GF AC   PF17029.9
#=GF DE   Domain of unknown function (DUF5100)
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   c_2261 - Hirt RP, Nakjang S
#=GF GA   27.00 27.00;
#=GF TC   52.60 52.40;
#=GF NC   24.20 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   24259309
#=GF RT   Reduction and expansion in microsporidian genome evolution: new
#=GF RT   insights from comparative genomics.
#=GF RA   Nakjang S, Williams TA, Heinz E, Watson AK, Foster PG, Sendra
#=GF RA   KM, Heaps SE, Hirt RP, Martin Embley T;
#=GF RL   Genome Biol Evol. 2013;5:2285-2303.
#=GF DR   INTERPRO; IPR031495;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of microsporidia-specific sequences of unknown
#=GF CC   function.
#=GF SQ   22
#=GS A0A4Q9M607_9MICR/1-125  AC A0A4Q9M607.1
#=GS R0M925_NOSB1/1-121      AC R0M925.1
#=GS L7JTK6_TRAHO/1-126      AC L7JTK6.1
#=GS T0LAD3_9MICR/1-122      AC T0LAD3.1
#=GS A0A0R0LZD1_9MICR/1-126  AC A0A0R0LZD1.1
#=GS A0A059EPL0_9MICR/1-125  AC A0A059EPL0.1
#=GS A0A437AIR7_9MICR/1-124  AC A0A437AIR7.1
#=GS L2GUR9_VAVCU/1-126      AC L2GUR9.1
#=GS S7W8P2_SPRLO/1-119      AC S7W8P2.1
#=GS Q8SV29_ENCCU/1-125      AC Q8SV29.1
#=GS A0A1X0Q772_9MICR/1-126  AC A0A1X0Q772.1
#=GS A0A0F9ZH31_9MICR/1-124  AC A0A0F9ZH31.1
#=GS J8ZW36_EDHAE/1-126      AC J8ZW36.1
#=GS I3EJV2_NEMP3/1-116      AC I3EJV2.1
#=GS A0A0B2UK20_9MICR/1-124  AC A0A0B2UK20.1
#=GS A0A1W0E404_9MICR/1-120  AC A0A1W0E404.1
#=GS A9CSD9_ENTBH/1-121      AC A9CSD9.1
#=GS A0A177EDU7_9MICR/1-115  AC A0A177EDU7.1
#=GS A0A1Y1S8C6_9MICR/1-121  AC A0A1Y1S8C6.1
#=GS H8Z9Q0_NEMS1/1-115      AC H8Z9Q0.1
#=GS A0A4Q9LKE0_9MICR/1-125  AC A0A4Q9LKE0.1
#=GS A0A059F1B8_9MICR/1-125  AC A0A059F1B8.1
A0A4Q9M607_9MICR/1-125             ......MNIENIYSKLIGILNIKHEqHNEICDILTATDTYTQT.KISNVEKFLCPTEANFQLPNVFLRTKKIAECEQLVGDRTH-VD...IEKWNECLNE-LEKICEFEFEEPEF.IESS.....ENDlYDEEFIERNIKQR-s.....
R0M925_NOSB1/1-121                 ......MSLKARIEKINRIITAQKS.TTDIIENLKPLEHLITEgLDNDQESCLYPNEPNFQLPNVFLKTKISSELKNYIKSNDG---...VSNFTTSIDLVLDKLESFELFETEI.NLKD.....--T.IEDEVLNFIVANR-e.....
L7JTK6_TRAHO/1-126                 ......MSNESKLQKILHILNSSAN.LENYIDMLESIDLVLNV.NDDEKDYFMCPEEANLQLPNVFLRQTKLLECKHFIKSKANNRI...GEHFYENCREILDFLESVELQEPEF.MESK....kKPD.IDVNLLRELVKKYI......
T0LAD3_9MICR/1-122                 ......MSYSENINKLKKASNFDLSnLKQIIDNFLPLQSYFFN.-VKNEDMCYVPMEANFQIPNVFLKTTINTACKKYIQENIE---...KNDFSKQINIIIEELDLFSFIDKHN.DYNE.....VVT.CDQSVLDELLSK--ky....
A0A0R0LZD1_9MICR/1-126             ......MSSQSNVRKILEQLNNTHN.LDSYTKMLDFFDQLVDL.PDDDEDVFLIPQEGNLQLPEIFLRDTFSVEHQEFLNKNTKLKK...EDDFEQICFDVLEYLETVELEEYEP.INKA....pEIP.IDSELLKKMVDKYF......
A0A059EPL0_9MICR/1-125             ......MDSEKKVKKIMAYLNIPYEqIDQLPDKISILETCLNT.-ESKESSFLLPTEANSQLPEIFLRTKLLDESNTFIDGNFTEVT...-ENWNKNIDKMISKWESFEFIENID.EEEL....pQKE.IDMDLLKKVIQ---lre...
A0A437AIR7_9MICR/1-124             ......MDSEKKAKKIISYLNIPFDlVEKFSDQLIALESCLNT.-ESKETCFLIPNEPNQQLPEVFLRTKLLDETECFINNNFIEEK...-DNWNDCIDEMITKWESFELFEPEE.DNFI.....KKE.ENLEDLKELITER-e.....
L2GUR9_VAVCU/1-126                 ......MSNESKLQKILSILNSPID.LEKYIEMLESIDLVLNV.NDDEKDYFICPEEANLQLPNVFLRQTKLLECKQFIKSKASSCM...GEHFYENCREILDFLESVELQEPEF.MESR....kKSD.IDVDLLRELVKKYI......
S7W8P2_SPRLO/1-119                 ......MLYSEKLEGIDAILSCFT-.LDDIFDILDTVSFYAST.-SDAKENFFIPQEANFQLPTIFLRTKRILDCEKFIYYNNGTFN...----NQKIDKILKCLEDIVIDEIVF.EEEK.....TVE.TNIQEVEELAKKYL......
Q8SV29_ENCCU/1-125                 ......MNIKSKYGKVIKALSIRQSdLWLVPRLMTPLENSFQTeAIDDEEVCIVPKEANFQLPNVFLRTGQNPEYQKLVDGGMP---...SSDWDDVIEETIEMLEEIDLSIGS-.---GgvmtrKCP.VDQGILNRLVFER-y.....
A0A1X0Q772_9MICR/1-126             mnfsrr-----ECEPIINKLKSIK-.IEDCTTSITAIESLLEQdSAFQNPSVVYPKEPNFILPNEFLQIKCETTVDNFFNKHKPKSNf.nYIEYNSNLDSLIDILDNYSMK--ER.SEES.....EIY.DNPEKLNEVIKDF-y.....
A0A0F9ZH31_9MICR/1-124             ......MDNHEKIWKLRKACGFNVDkLNAIIENFLPLENHFLNiDENLKTFCYVPNEANFQLPNIFLKTSLTSACTKYLQSNVE---...KNDYSKTIDLIIDELEVLR-EDFDFlEIES.....HEN.IAENTLSSIYKKR-y.....
J8ZW36_EDHAE/1-126                 ......MNISLQLEKMIDALNISPDeIDTFLTSISSLKLIMQQ.KHTGITSFVVPQQANFQLPDIFLRTKQIPECEKFMRENSKKIS...IKEWNENIDNSLNIIAEYELEQEEF.DDED.....ISP.FDDEFVKNNIQDIM......
I3EJV2_NEMP3/1-116                 ......------MEQLKEILKNKK-.--NPLKRAESLNIILES.-EECEGISLVPSTANFQIPEVFLSTKILPECETYFIQERSRISpvqVEEWNNRVDSVIDEL------SVEF.TISNpvhtkHIP.SDHEVIEA-VKEV-l.....
A0A0B2UK20_9MICR/1-124             ......MNMKSKYNKVIKTLSICQEdIWNALKMIIPLENSFNTeTIDDNEVCVVPNEANFQLPNVFLRTAPNPGYQKLINCNVNAVE...---WNKVVDEVLEMFEEMEIISVPE.VLAQ.....RCP.VQQDVLKRMVCER-y.....
A0A1W0E404_9MICR/1-120             ......MNRKKLHSKLNELLKNTT-.NENLLETINNIEYQINQ.CTNTSSTAIIPQEANFQLPTQFLGIKKNVEIEGLFIESNK---...TSVNDEKIDRIVTFLEETM-GNESF.STMA.....TAK.NKKHNIEKLVKKK-y.....
A9CSD9_ENTBH/1-121                 ......MERERLHEKIEKILHNMN-.INNLLESIDSFEFYLKQiKRKNNEIF-IPQEANFQLPNQFLELHQNNEIEKVLSSSHKCVI...---NNDAINQIMDYLDQISINSIDD.NNNQ.....YIP.NDQQTIFLINKKYF......
A0A177EDU7_9MICR/1-115             .....m-------ERLRQIIQKKE-.---SLKRAEAMCTMLET.-DEHNEVALIPAEANFQLPDIFLSTRILPECETYFIRESTVLAppqVEAWNSNIGQALEAL-TIHMSISPK.DPPK.....HLV.TEEELVTR------ieevl.
A0A1Y1S8C6_9MICR/1-121             ......MTKKQLHEKLSSLLDNIE-.YSNMLDSFTTIIYNLQQ.EDKNDGKLLIPLEANFQLPNQFLGVKTNMAAERFLSEANK-LN...VDENK--ILAAQIYLQDTGLSIVET.ETTE.....AKQ.SQNQISEF------vrrkff
H8Z9Q0_NEMS1/1-115                 .....m-------DRLRQILSKK--.--NALKRAEGLNAILEG.-EECEGIALVPGTANFQIPEVFLSTKILPECETYFIQKRKPIQadeIERWNQAIDDVIDGL-SVEFTISSS.VHSK.....DAP.SEREVSDR-IKKV-l.....
A0A4Q9LKE0_9MICR/1-125             ......MNIENIYSKLIGILNIKHEqHNEICDILTATDTYTQT.KISNVEKFLCPTEANFQLPNVFLRTKKIAECEQLVGDRTH-VD...IEKWNECLNE-LEKICEFEFEEPEF.IESS.....ENDlYDEEFIERNIKQR-s.....
A0A059F1B8_9MICR/1-125             ......MDSEKKVKKIMAYLNIPYEqIDQLPDKISILETCLNT.-ESKESSFLLPTETNSQLPEIFLRTKLLDESNTFIDDNFTEVT...-ENWNKNIDKMISKWESFEFIENID.EEEL....pQKE.IDMDLLKKMIQ---lre...
#=GC seq_cons                      ......Ms.cpphpKlhphLshptp.lpphh-plpsl-thlps..csspshhllPpEANFQLPslFL+T+h.sEscpalppstp.ht...hppascsIcphl-hL-phchppsc..pppp.....phs.h-p-hlcchlpch.......
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