#=GF ID   DUF5347
#=GF AC   PF17282.6
#=GF DE   Family of unknown function (DUF5347)
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   PRODOM:PD073252
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.10;
#=GF NC   23.60 24.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR035232;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of unknown function is found in Bacteria, mainly in
#=GF CC   Proteobacteria.
#=GF SQ   60
#=GS Q8ZMS0_SALTY/10-111      AC Q8ZMS0.1
#=GS A0A8J7H628_9ENTR/10-128  AC A0A8J7H628.1
#=GS A0A485AIC9_KLUCR/10-110  AC A0A485AIC9.1
#=GS D2U2E2_9GAMM/15-107      AC D2U2E2.1
#=GS A0A482MFF5_9CAUD/10-111  AC A0A482MFF5.1
#=GS A0A4R6EKI7_9ENTR/11-111  AC A0A4R6EKI7.1
#=GS M1SML3_MORMO/30-134      AC M1SML3.1
#=GS C0B376_9GAMM/32-129      AC C0B376.1
#=GS A0A378AF30_KLEPO/10-110  AC A0A378AF30.1
#=GS D3VKP1_XENNA/10-110      AC D3VKP1.1
#=GS A0A218M4I7_9CAUD/10-110  AC A0A218M4I7.1
#=GS W1HRQ7_KLEPN/10-44       AC W1HRQ7.1
#=GS A0A2U8I308_9GAMM/10-104  AC A0A2U8I308.1
#=GS W1IZH8_9GAMM/10-111      AC W1IZH8.1
#=GS X0PG10_9LACO/79-174      AC X0PG10.1
#=GS A0A4R1N8Y7_9GAMM/1-34    AC A0A4R1N8Y7.1
#=GS A0A068QW11_9GAMM/15-116  AC A0A068QW11.1
#=GS A0A2D0KM11_9GAMM/15-115  AC A0A2D0KM11.1
#=GS A0A2D0KQX3_9GAMM/10-114  AC A0A2D0KQX3.1
#=GS A0A4Z0KPV3_SALET/10-110  AC A0A4Z0KPV3.1
#=GS A6TE83_KLEP7/10-110      AC A6TE83.1
#=GS A0A482J2U5_9CAUD/10-111  AC A0A482J2U5.1
#=GS A0A378E4V7_KLEPR/1-79    AC A0A378E4V7.1
#=GS W1HPW8_KLEPN/1-72        AC W1HPW8.1
#=GS A0A5Q2KCQ1_9ENTR/10-110  AC A0A5Q2KCQ1.1
#=GS A0A328TMK1_9GAMM/10-111  AC A0A328TMK1.1
#=GS A0A068QXP1_9GAMM/10-110  AC A0A068QXP1.1
#=GS A0A482IH07_9CAUD/1-99    AC A0A482IH07.1
#=GS E0WV64_9ENTR/13-107      AC E0WV64.1
#=GS Q6D3W1_PECAS/10-111      AC Q6D3W1.1
#=GS W1JBK8_9GAMM/10-110      AC W1JBK8.1
#=GS E3G7S0_ENTLS/9-109       AC E3G7S0.1
#=GS A0A0J8YNY1_9GAMM/9-109   AC A0A0J8YNY1.1
#=GS A0A1S6L019_9CAUD/10-111  AC A0A1S6L019.1
#=GS A0A4P7J481_9ENTR/10-111  AC A0A4P7J481.1
#=GS A0A0C2NF81_THEKT/10-110  AC A0A0C2NF81.1
#=GS B4F0M0_PROMH/32-129      AC B4F0M0.1
#=GS B2VHC5_ERWT9/10-111      AC B2VHC5.1
#=GS W1DLR3_KLEPN/10-111      AC W1DLR3.1
#=GS D3UZP6_XENBS/15-115      AC D3UZP6.1
#=GS A0A0R2AFP6_9LACO/79-174  AC A0A0R2AFP6.1
#=GS A0A482J8G6_9CAUD/10-111  AC A0A482J8G6.1
#=GS A0A427KC46_9GAMM/10-111  AC A0A427KC46.1
#=GS D3V9L4_XENNA/10-110      AC D3V9L4.1
#=GS E1SEW5_PANVC/1-99        AC E1SEW5.1
#=GS J7TAM8_MORMO/13-113      AC J7TAM8.1
#=GS A0A2V1HID6_9GAMM/26-104  AC A0A2V1HID6.1
#=GS A0A482J8F9_9CAUD/10-111  AC A0A482J8F9.1
#=GS E5G6L5_9CAUD/10-111      AC E5G6L5.1
#=GS K0DFK1_LEUCJ/79-174      AC K0DFK1.1
#=GS D3V0F3_XENBS/10-110      AC D3V0F3.1
#=GS A0A2D0KBG4_9GAMM/10-110  AC A0A2D0KBG4.1
#=GS A0A014M2B7_9GAMM/10-111  AC A0A014M2B7.1
#=GS A0A2Z2FD91_9CAUD/1-44    AC A0A2Z2FD91.1
#=GS A0A4Z0QLI2_SALET/10-111  AC A0A4Z0QLI2.1
#=GS W1IS56_9GAMM/15-115      AC W1IS56.1
#=GS D8MP55_ERWBE/10-111      AC D8MP55.1
#=GS U3U747_9ENTR/1-72        AC U3U747.1
#=GS A0A4P8YGB1_9ENTR/10-111  AC A0A4P8YGB1.1
#=GS W1J7F5_9GAMM/1-66        AC W1J7F5.1
Q8ZMS0_SALTY/10-111                 ..........................................VPLSPGKRLDGLNHIAELRAKVFG.lNI..................ESE.....LERFIEDMRDQRDVNNKQNERALAAIFYMAKIPAERHSVNISDLTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
A0A8J7H628_9ENTR/10-128             .........................................v-NFNAGQRLCGLNKIAEIRAEMRE..INkrvkqqdkknrpvphaimDKD.....LARFLADMRDEHDKKYEQNNRALSALFYLAGIKTARHGVDVVEMSDQEKKALIIAMNHFRVMVSLF..SERLTL..
A0A485AIC9_KLUCR/10-110             ..........................................VPLKVGERFNALNHIAELRARYWG..DS..................WKE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELELSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
D2U2E2_9GAMM/15-107                 ........................................tg--LSINQRFDGLIRCAQLRTVYFN..NDp................nNKC.....LSDFIEYLRK-------HNKRFVNLIFYLANIDNKKHHLKFD---NQEKQAIIYAIFQLQALVGLI..PKNIVI..
A0A482MFF5_9CAUD/10-111             ..........................................VPLSPGHRLDGLNHIAELRAKVFG.lNI..................EPE.....LERFISDMRDQRDINHKQNERALAAIFFMAKIPADRHNVNMNELTTDEKRELIKAMNHFRAVVSLF..PKRLSM..
A0A4R6EKI7_9ENTR/11-111             .......................................sis----PGERYEGLNHIAELRAKVFG.hNV..................ESE.....LERFIEDMSDPRDANNKQNKRALAAIYFMANIPAERHSVKISELTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
M1SML3_MORMO/30-134                 ..........................................VSMAIDEKIDGMNLAAKMRANLFQ.iQGk...............plNAG.....MDDFMKELRSHSNNKVRNNNRVLSMIFFLAEIEKEKHSFKFEQLTHNEQVRFIEAINQIKAVASIF..PTDLAI..
C0B376_9GAMM/32-129                 .........................................g--LSFDERVSGMNKTAEVRADLLSklNKn...............sdDIQ.....VSEFLDYLRN-------ENNRIYQMIYYLAEIEKEKNGTDYLLLKRKDKIKIINALHQIKVLSALI..PNKLAM..
A0A378AF30_KLEPO/10-110             ..........................................VPLKAGERLAGLNHVAQLRARYWG..DC..................WKE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELQLSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
D3VKP1_XENNA/10-110                 ..........................................VVLTLDERIDGLNAAAELRHKVFS..DD..................NSE.....LAEFMEYMRDRTNNRVRNNERILHLIFHLAGFDKSRYDVKFNELTKNEQRALILAMNQFKAVASIL..PAKLVL..
A0A218M4I7_9CAUD/10-110             ..........................................VPLKVGERFNALNHIAELRARYWG..DS..................WQE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELELSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
W1HRQ7_KLEPN/10-44                  ..........................................VPLKAGERLAGLNHVAELRARYWG..DS..................WKE.....VERFC-------------------------------------------------------------..------r.
A0A2U8I308_9GAMM/10-104             .......vplnleqrqcslkhiallwglfpdakykgvipali------------------------..--..................---.....-----TEMQE-------TDPQMKGALYYLAGIEKKKHALAFKQLSPEEQMNIIDAIIRLRAVISLL..PDRV--ty
W1IZH8_9GAMM/10-111                 ..........................................VILTLDEKIDGMLNTAQIKNRVLK.qNS..................DKA.....IAEFIKNMRDRTNNRSRNNERVLHSILHLAGFPKSKYGTPYESFTYDEKKAFIEAIIQFKAVASLM..PESI--af
X0PG10_9LACO/79-174                 .......................ahivpilasdfsedelrqr------------------------..--..................YPS.....LQAFVTAIFTDRVAFAKANVKELKVIFEMAAFDTERREQILSQIAPKMVKQMGSVINQLKADHLIVdwPNDL--il
A0A4R1N8Y7_9GAMM/1-34               ..........................................------------------------..--..................---.....--------------------------------------MDFQDLLVNERKAVIRALNEIQALAAFL..PQRLE-i.
A0A068QW11_9GAMM/15-116             ..........................................VEMPFEMRVNGLNSVAKLKAEVFK.sSD..................NKE.....LTLFVDEMRNKRNAHYADNKRFLAAIFYLAYIPTERHELELNQFTREEMCSLIRAINLIRAASPLL..PSKLSL..
A0A2D0KM11_9GAMM/15-115             ..........................................FPMDFETRVNGLNQLAQIRAKLFK..SA..................NEQ.....LAAFIDEMRDKRNEHYADNIRLLGAMFYLANIPKERHKLELDQFTREEKISITKAANLIKAAGALL..PNNLSL..
A0A2D0KQX3_9GAMM/10-114             ..........................................VVLTLDERIDGMCQVAKTRASVFS..GSvs..............asDKA.....IAEFIKNMRDRTNNRKRNNKKLLHVLFHLAGLPKSRYDAQYEDFTLDERHSLIEAFMQYKAVAAIM..PESFA-i.
A0A4Z0KPV3_SALET/10-110             ..........................................VPLSAGLRLNGLNHIAELRAKVFG.lNI..................DSE.....LERFISDMRDQRDINHEQNKRALAAIFFMAKISVERHSVNVSELTTDEKRELIKAMNHFRAVVSLF..PKRLT-..
A6TE83_KLEP7/10-110                 ..........................................VPLKAGERLAGLNHVAELRARYWG..DS..................WKE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELQLSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
A0A482J2U5_9CAUD/10-111             ..........................................VPLSPGERLNGLNHIAELRAKVFG.lNI..................ESE.....LERFIKDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLF..PRRLTM..
A0A378E4V7_KLEPR/1-79               ......................................matv------------------------..--..................KKE.....LNRFINEMRDKRDEKYELNNRVLAALFFLANISKERHCVEFSELTSDEVTALIGVMNHLRAVVSLF..PKRLAM..
W1HPW8_KLEPN/1-72                   ..........................................------------------------..--..................---.....MNVFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELELSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
A0A5Q2KCQ1_9ENTR/10-110             ..........................................VPLKAGERLAGLNHVAELRARYWG..DS..................WKE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELELNELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
A0A328TMK1_9GAMM/10-111             ..........................................VAMTTGARAAGLNHVAEVRSRFWG.dDS..................EKD.....ISRFMNDMRDVRDSNYHENKRALSAIFYLANIKTERHELDFSELITDERNALIRAMNHFRAVVSLF..PKRLTL..
A0A068QXP1_9GAMM/10-110             ........................................aq--INLGQRLEGLNHLSRIRATYWG..EN..................ETE.....LNRFLADMRDKTDSYYEENKRALSAIFYLANIPRSRHDSEFNHFTQAEKQALIKAMNHIKVVVSQF..PKHLTL..
A0A482IH07_9CAUD/1-99               ..........................................--MSAGQRASALNHISVLRTALYG..DC..................EKE.....LNRFINEMRDKRDEKYELNNRVLAALFFLANISKERHCVEFSELTSDEVTALIGVMNHLRAVVSLF..PKRLAM..
E0WV64_9ENTR/13-107                 vplnlaqrqcglrnttllwqvlpdkkyqgqipalikemeetd------------------------..--..................---.....-------------------PQMKGALYYLAGIERKKHALAFKQLYPEEQINLIDAMNRLRAAVSLF..PNRI--ty
Q6D3W1_PECAS/10-111                 ..........................................VPLSIAARTDGLNHIAMLRGKHFN.tNS..................EKD.....MCRFIDDMRDKIDGDYHQNMRVLSAIFELADIDKERRNMKFNELTTEEKAKLIKAMNKLKAVVSLF..PKHLIL..
W1JBK8_9GAMM/10-110                 ........................................aq--INLGQRLEGLNHLSRIRAIYWG..NN..................EKE.....LRRFLADMRDKRDCHYEENKRVLSAIFYLANIPRSRHDSEISQFTPEEKRSLIKAMNHIKVVVSQF..PKHLTL..
E3G7S0_ENTLS/9-109                  .........................................a-ELSVGKRTEGLNRIAEIRMQHWG..DD..................GKA.....LQRFIDDMRDRRDPLSTENRRALSALFFLANIPSSRHELALNELTAQEKRALIQAMNQCRAMVSLF..PKRLTM..
A0A0J8YNY1_9GAMM/9-109              ........................................eq--LNAGQRVLALNHIAAIRGQFWG..DS..................WKE.....VERFIDDMRDPRDSNNEENIRTLSATFYLAKIPTNKHHLSLSELTIDERTALVSAMNQLKAVVSLF..PKRIAL..
A0A1S6L019_9CAUD/10-111             ..........................................VPLSAGLRLNGLNHIAELRAKVFG.lNI..................DSE.....LERFISDMRDQRDINHEQNKRALAAIFFMAKIPAERHSVNVSELTTDEKRELIKAMNHFRTVVSLF..PNRLAM..
A0A4P7J481_9ENTR/10-111             ..........................................VPLSAGLRLNGLNHIAELRAKVFG.lNI..................DSE.....LERFISDMRDLRDINHKQNKRALAAIFFMAKIPAERHSVNVSELTTDEKRELIKAMNHFRTVVSLF..PNRLAM..
A0A0C2NF81_THEKT/10-110             ..........................................VPLKAGERLAGLNHVAELRARYWG..DS..................WKE.....VERFVDDMRDKRDPQFEENNRALAAIFFLAKIPAARHELELSELTTDEKKALITAMNHFRAVVSLF..PKRLTM..
B4F0M0_PROMH/32-129                 .........................................g--LSFDERVSGMNKTAEVRADLLS..KL..................NKNsddilIGEFLDYLRN-------ENNRIYQMIYYLAEIEKEKNGIDYLLLKRKDKIKIINALHQIKVLSALI..PNKLAM..
B2VHC5_ERWT9/10-111                 .........................................i-PLSPGERLEGLNHIAELRAKVFG.lDI..................EPE.....LERFIKDMRAPRDVNHKQNERALAAIFYMAKIPAERHGVNISDLTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
W1DLR3_KLEPN/10-111                 ..........................................VPLSPGERLNGLNHIAELRAKVFG.lNI..................ESE.....LERFIKDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLF..PRRLTM..
D3UZP6_XENBS/15-115                 ..........................................FPMSFEMRANGLNQLAQIRAQHLK..SG..................NEQ.....LATFIDEMRDKRNEHYADNIRMLGAMFYLAHIPKERHKLKLNQFTSEERINLIKAVNLIKAASAVL..PEGLSL..
A0A0R2AFP6_9LACO/79-174             .......................ahivpilasdfsedelrqr------------------------..--..................YPS.....LQAFVTAIFTDRVAFAKANVKELKVIFEMAAFDTERREQILSQIAPKMVKQMGSVINQLKADHLIVdwPNDL--il
A0A482J8G6_9CAUD/10-111             ..........................................VPLSPGERLNGLNHIAELRAKVFG.lNI..................ESE.....LERFIKDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLF..PRRLTM..
A0A427KC46_9GAMM/10-111             ........................................ae--IRTGARVAGLNHVAELRSKFWG..ND.................cGKD.....ITRFFNEMRDTTDRNYQENKRALSAIFYLANIRTERHELDFSELTTNERSALIRAMNHFRAVVSLF..PKRMTL..
D3V9L4_XENNA/10-110                 ........................................aq--INLGQRLEGLNHLSRIRAIYWR..DD..................EKE.....LNRFFADMRDKRDSHCEENKRVLSAIFYLANIPRSRHDSEFNHFTQEEKQALIKAMNHIKVVVSQF..PKYLVL..
E1SEW5_PANVC/1-99                   ..........................................--MNAGQRASALNHISALRTMMYG..DC..................SHE.....LKRFIADMRNKRDHQAEQNGRALSAIFFLANISKERHSVDFSELTSDEVKALISAMNHLKAVVSLF..PKNLTL..
J7TAM8_MORMO/13-113                 ..........................................FPIPISKRADGLNHIAKLRSERFG..IE..................NKE.....LESFFKEMRDRFDSMYKDNKKFLGVILYMANIEKERHDCDYNDFSSKEIFNIVKAINHIRAISAIL..PKHLVL..
A0A2V1HID6_9GAMM/26-104             ...............eyldksmrmiaavksrnesqsfinalg------------------------..--..................---.....-------------------ARHKGLIYFMAEITRERHKLKFEQLTEHERKAVICAMRDLKELAASL..PKRI--c.
A0A482J8F9_9CAUD/10-111             ..........................................VPLSPGHRLDGLNHIAELRAKVFG.lNI..................EPE.....LERFISDMRDQRDINHKQNERALAAIFFMAKIPADRHNVNMNELTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
E5G6L5_9CAUD/10-111                 ..........................................VPLSPGERLNGLNHIAELRAKVFG.lNI..................ESE.....LERFIKDMRNPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLF..PRRLTM..
K0DFK1_LEUCJ/79-174                 .......................ahivpilasdfsedelrqr------------------------..--..................YPS.....LQAFVTAIFTDRVAFAKANVKELKVIFEMAAFDTERREQILSQIAPKMVKQMGSVINQLKADHLIVdwPNDL--il
D3V0F3_XENBS/10-110                 ........................................aq--INLGQRLEGLNHLSRIRATYWG..DD..................EKE.....LNRFFADMRDKKDSYYEENKRALSAIFYLANIPRARHESELEHFTPEEKQALIKAMNHIKVVVSQF..PKYLKL..
A0A2D0KBG4_9GAMM/10-110             ........................................aq--INLGQRLEGLNHLSKIRSIYWG..YD..................EKE.....LKRFFADMRDKRDCHYEENKRALSAIFYLANIPRARHDSEISQFTSEEKHSLIKAMNHIKAVVSQF..PRHLTL..
A0A014M2B7_9GAMM/10-111             ..........................................VPLSPGQRLDALNHIAELRAKVFG.lNI..................EPE.....LERFIKDMRDPRDMNHKHNERALAAIFYMARIPAERHGVNISDLTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
A0A2Z2FD91_9CAUD/1-44               ..........................................------------------------..--..................---.....----------------------------MAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLF..PRRLTM..
A0A4Z0QLI2_SALET/10-111             ..........................................VPLSPGKRLDGLNHIAELRAKVFG.lNI..................ESE.....LERFIEDMRDQRDVNNKQNERALAAIFYMAKIPAERHSVNISDLTTDEKRELIKAMNHFRAVVSLF..PKRLTM..
W1IS56_9GAMM/15-115                 ..........................................FPMPFEIRANGLNKLAQLRAEHFK..SA..................NEQ.....LAAFMDDMRDKRNEHYADNIRLLSAILFLAHIPKARHGLELNQFTREEKIELIKAVNLIKAASPLL..PNNLSL..
D8MP55_ERWBE/10-111                 ..........................................VPMTAGERVKGLSHIANLRTKVFG..ES.................cGDE.....LKRFMFDMRDKRDVYFEKNKRALSAIFFLANLKSERHECDFDELTSDEKYALIGAMNHFRAVVSLF..PKKLSL..
U3U747_9ENTR/1-72                   ..........................................------------------------..--..................---.....MARFFSEMRDVTDSNYRDNKRALSAILFLANIGKDRHDAEFSELTTDERKALICAMNNLKAVVSLF..PKRMTL..
A0A4P8YGB1_9ENTR/10-111             ........................................tp--LSPGERVDGLNHIAELRAKVFG.lNI..................EPE.....LERFINDMRDLRDSSYQQNERALAAIFYMAKIPADRHSVKINELTTDERRALVQAMNHFRAVVSLF..PKRLTM..
W1J7F5_9GAMM/1-66                   .........................................m------------------------..--..................---.....-------MRDRSNNRIRNNERVLHLIFHLAGFDKSQFNNELKDFTPEEQRSLISAIHQFKAVAAEL..PDKLVM..
#=GC seq_cons                       ............................................lshupRlsGLN+lAclRuphau..s...................pp-.....LpRFls-MRDpRD.phcpNpRsLuAIFaLApIstcRHslphs-LTs-EK+sLIpAMNHh+AVVSLF..P++Lsh..
//