#=GF ID   DUF5592
#=GF AC   PF17332.6
#=GF DE   Family of unknown function (DUF5592)
#=GF PI   pXO2-11;
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   PRODOM:PD286107
#=GF GA   26.70 26.70;
#=GF TC   27.40 27.30;
#=GF NC   26.60 26.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR020275;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of unknown function found in Bacilli.Family
#=GF CC   members contain two predicted trans-membrane regions.
#=GF SQ   49
#=GS A0A1I1ZPA7_9BACI/3-91  AC A0A1I1ZPA7.1
#=GS A0A4Y9ACF5_9BACI/3-91  AC A0A4Y9ACF5.1
#=GS A0A1G8KJH4_9BACI/3-91  AC A0A1G8KJH4.1
#=GS A0A6S6XKZ4_9FIRM/5-95  AC A0A6S6XKZ4.1
#=GS A0A5R8Q6W8_9FIRM/3-90  AC A0A5R8Q6W8.1
#=GS G5KEY0_9STRE/5-94      AC G5KEY0.1
#=GS A0A396QA61_9FIRM/3-91  AC A0A396QA61.1
#=GS I0JSC1_HALH3/6-94      AC I0JSC1.1
#=GS D7V1F8_LISGR/10-98     AC D7V1F8.1
#=GS D4M177_9FIRM/3-88      AC D4M177.1
#=GS A0A0R1RGY5_9LACO/1-77  AC A0A0R1RGY5.1
#=GS A0A5R9EGF5_9LACT/5-93  AC A0A5R9EGF5.1
#=GS F7JRZ7_9FIRM/3-91      AC F7JRZ7.1
#=GS A0A6I1MP21_9CLOT/3-89  AC A0A6I1MP21.1
#=GS A0A1G8Q6I8_9BACI/4-92  AC A0A1G8Q6I8.1
#=GS A0A345C0W6_9BACI/3-91  AC A0A345C0W6.1
#=GS A0A1E5L0E4_9ENTE/9-91  AC A0A1E5L0E4.1
#=GS I0JIN6_HALH3/3-91      AC I0JIN6.1
#=GS A0A419SQ41_9BACL/4-92  AC A0A419SQ41.1
#=GS A0A1L8PLR3_9LACT/5-93  AC A0A1L8PLR3.1
#=GS A0A841PM70_9BACL/3-91  AC A0A841PM70.1
#=GS A0A0B0D553_9BACI/3-91  AC A0A0B0D553.1
#=GS A0A549YHS2_9BACI/3-91  AC A0A549YHS2.1
#=GS A0A6P1B1S2_9BACT/2-63  AC A0A6P1B1S2.1
#=GS A0A2A8S6H1_9BACI/4-92  AC A0A2A8S6H1.1
#=GS L5NA40_9BACI/4-92      AC L5NA40.1
#=GS F9PX67_9STRE/6-95      AC F9PX67.1
#=GS Q93M98_CLOPE/3-91      AC Q93M98.1
#=GS A0A059NXV9_9BACI/3-91  AC A0A059NXV9.1
#=GS Q1WR78_LIGS1/4-95      AC Q1WR78.1
#=GS R3WMF7_9ENTE/4-92      AC R3WMF7.1
#=GS K2GLQ4_9BACI/3-91      AC K2GLQ4.1
#=GS A0A856M596_9BACI/5-92  AC A0A856M596.1
#=GS A0A437K413_9BACI/2-91  AC A0A437K413.1
#=GS A0A176U332_9FIRM/3-92  AC A0A176U332.1
#=GS B9EC73_MACCJ/10-100    AC B9EC73.1
#=GS A0A844LSW9_9BACI/3-91  AC A0A844LSW9.1
#=GS T0D3R2_PAES9/2-90      AC T0D3R2.1
#=GS A0A7H8SAN8_9BACI/3-91  AC A0A7H8SAN8.1
#=GS L5N6E4_9BACI/3-91      AC L5N6E4.1
#=GS A0A1H9I032_9LACT/5-92  AC A0A1H9I032.1
#=GS S0KIP7_9ENTE/2-90      AC S0KIP7.1
#=GS A0A2L1FFS9_9BACI/4-92  AC A0A2L1FFS9.1
#=GS A0A0K9H0Z6_9BACI/4-92  AC A0A0K9H0Z6.1
#=GS A0A0E4CSZ7_9STRE/5-94  AC A0A0E4CSZ7.1
#=GS W7CA43_9LIST/2-91      AC W7CA43.1
#=GS A0A4Y9A8W4_9BACI/3-91  AC A0A4Y9A8W4.1
#=GS A0A366I1L2_9FIRM/2-91  AC A0A366I1L2.1
#=GS A0A0M1V0S0_PAESO/2-90  AC A0A0M1V0S0.1
A0A1I1ZPA7_9BACI/3-91             ..............YEIPKEIKAKPKILG..-LEMREL.V.ILLI.SSLlVLT.IL.RDLV..H...SVF....MI..P....YFLTV...IGFM...IYLFM..PSGHNPKKRHYESLILYFRHKKTGYYAMD..........
A0A4Y9ACF5_9BACI/3-91             ..............YEIPKEIKAKPKILG..-LEMREL.V.ILLI.SSLlVLT.IL.RDLV..H...SVF....MI..P....YFVAV...IGIM...IYLFM..PSGHNPKKRHYESLILFFRHKKAAYHAMD..........
A0A1G8KJH4_9BACI/3-91             ..............YKIPTEITAELKLNK..WFYLTDL.L.VAIG.MLV.MGF.VL.HAMI..H...PSL....TI..P....FIIFM...VALY...GFWLW..KPKTNPHMRMLSAVWMMLSRDRATYHAHD..........
A0A6S6XKZ4_9FIRM/5-95             ..............YIIPKQLREEYKIFDrpTIFLKDV.V.TGVI.LLG.LFF.MF.KNLV..H...AWL....LV..P....YWIIA...IAVI...FFLIQ..PSASNPKKRNWEALILFLGRDRITYYSL-n.........
A0A5R8Q6W8_9FIRM/3-90             tkissqlvdgvkfg---------------..PIYLFDV.LgAIAF.IGV.FGF.IL.AEYI..H...SYV....YW..F....YLVWI...VIVA...IYAIL..PAAQNKGIRNYKAMIWWL-----------qervkqqlfe
G5KEY0_9STRE/5-94                 ..............YGVPRDIYAKVKIIG..-LFISDI.V.LIGG.SAL.IGI.TI.APKI..F...PTD....MW..LqmfaFIILT...PIIT...LFLVL..--PNNGGKRNWQCMYLYFRRKRRRYISI-n.........
A0A396QA61_9FIRM/3-91             ..............YLVTQEIKSPSKVGK..GLYVQDF.F.FLII.YGG.LSV.VS.SGLV..N...GSL....LL..P....YGIFS...GCMA...LGLTA..SSAKNRKRRNLQSMILYIRKSRSVYNPI-q.........
I0JSC1_HALH3/6-94                 ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...SSF....VW..Y....YAIFW...IVLM...VAWLI..RPKTNPKLRMAKALFLAVTRDRVTYCAID..........
D7V1F8_LISGR/10-98                .............i-TIPKEIKSEIKLKK..NIYLKDF.F.TMIG.LIP.ITM.IF.MNFV..H...SSV....MY..Y....FYGLM...AVIA...ITLLI..RPKSNPDLRIYSAVYLALTRNRARYRAVD..........
D4M177_9FIRM/3-88                 ..............YLVTKEIKSETQVIW..KLYLQDF.V.FLSV.WIF.LCL.NL.KENV..H...EYL....QI..P....YLIFS...GMIG...ICLMI..PAVGNPKRRIYQAIALYLLKPKKV-----ig........
A0A0R1RGY5_9LACO/1-77             .............m---------------..-LYAVDI.G.VFAL.VFG.LSM.FI.GESM..F...PTSqmlqKI..F....FYICA...FILG...IYLIM..RPRTNPGRENWRILLMLL-----------tnwpdhgyqs
A0A5R9EGF5_9LACT/5-93             .........rlitt------LSPEAKIGS..WLYFTDLfA.VLLG.LAV.FIL.TH.ELFG..Y...LLL....KA..V....YGIVI...AIIA...LWSVI..RPRNNPFKRNYQVVVFAFKRDKTIYHM--vn........
F7JRZ7_9FIRM/3-91                 ..............YIVTQEIKSETQVLW..FIYLQDL.A.FLTV.WIM.LVL.VL.KENV..H...GYL....RI..P....YYMFS...FVVG...VRMVL..RVKGNPKRRYYQALAIYIGRPKNIYR---yfk.......
A0A6I1MP21_9CLOT/3-89             ..............YNIPKEITSEMKFSK..NIYLFDL.A.TICG.AMT.IAW.LL.SPLV..Y...SSF....RN..I....FYVFI...LIAS...IFMVN..KSRVNPKKRNYQSIYYALIRNRNTYS---r.........
A0A1G8Q6I8_9BACI/4-92             ..............YRIPKDMTSELKINK..ALYLTDF.F.ILVG.LIP.FTM.VM.SNIV..H...DSL....LW..Y....FYLFM...VIVA...GLLII..RPATNPKKRIYEAVYYAICRRKDTYTAID..........
A0A345C0W6_9BACI/3-91             ..............YKIPTEVTAELKLNR..WLYLTDL.L.VAIG.MLV.MGF.IL.HALI..H...PSL....TI..P....FVVFM...VALY...GFWLY..RPKTNPHMRMIQVVWMMLSRDRATYHAHD..........
A0A1E5L0E4_9ENTE/9-91             ......esirpkre------------IKG..WLSLPDF.I.FIIV.VTV.ISF.FI.RGIV..F...PLF....EI..P....FVIFT...FLNA...VFLVK..PPKENPKQKNYNMLWLILRR---------yffkeyl...
I0JIN6_HALH3/3-91                 ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...PSL....VW..Y....YVIFW...IVLM...VAWLI..RPKTNPKLRMAKVLVLAVSRDRVTYCAVD..........
A0A419SQ41_9BACL/4-92             ..............YRIPSEISTELKINK..ALYLFDL.L.FIIG.LIV.FRM.IV.LPFI..H...SSF....TW..Y....FTIFL...VIFG...GFMLI..RPSGNPQKRMYHAIYYAMIRRKDAYSAID..........
A0A1L8PLR3_9LACT/5-93             ..............YRIPREMKADIKLW-..FIYLSDI.P.FIAG.MII.FTM.FT.APIL..AetgTTL....RF..A....YYIFN...VVFT...FIFIA..KPI--PQKSVFNLMVQSLRQDLKKYRSVD..........
A0A841PM70_9BACL/3-91             ..............YKIPTEITAELKLNR..WLYLTDL.L.VAIG.MLV.MGF.VL.HALI..H...PSL....TI..P....FVIFM...VALY...GFWLY..RPKTNPHMRMIQAVWMMISRDRATYQAHD..........
A0A0B0D553_9BACI/3-91             ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...FSF....VW..Y....YAIFW...IILM...VALLI..RPKTNPKLRMVKALFLAVTRDRIAYCAID..........
A0A549YHS2_9BACI/3-91             ..............YEIPKEIKAKPKILG..-LEMREL.V.ILLI.SSLlVLT.IL.RDSV..H...SVF....MI..P....YFLAV...IGFM...IYLFM..PSGHNPKKRHYESLILFFRHKKTGYHAMD..........
A0A6P1B1S2_9BACT/2-63             ........tlflln---------------..-------.-.----.---.---.VG.SEFV..H...NWF....TI..P....YYIVG...FGAL...LFMVM..SSSTNPGKRNYVALYFLIKRNKTTYHPID..........
A0A2A8S6H1_9BACI/4-92             ..............YRIPKEISTELRINK..VLYLLDF.S.LIIA.VLV.VTM.IL.RNFV..H...DSL....QI..P....FCIFM...GSVA...IIMIW..RPSTNPQKRMYEVLIITIMRRKGAYCAID..........
L5NA40_9BACI/4-92                 ..............YRIPKNVTSELKINK..ALYLTDL.G.ILVG.LLL.FTF.VM.SNVV..H...ASF....TW..L....FYIFM...IIVA...GLTII..RPATNPKKRMYEAIYLSLRRRKDTYIAID..........
F9PX67_9STRE/6-95                 ..............YGVPRDIYAKIKIIG..LL-ILDI.A.FVGI.TGV.IAL.SV.GLKI..F...PKS....QW..I....QMFAF...ILLTpvmSLYLV..L-PANGGKKNWHSMFLFFRRRRKRYISL-n.........
Q93M98_CLOPE/3-91                 ..............YNIPKEISTEMKFTS..KIYLFDF.A.MLLV.ALI.FAT.IF.SGLV..Y...PSL....RV..L....FYIFV...AIST...IFLVN..KSIINPKKRNFQTVYLALVRDKKVYVAEK..........
A0A059NXV9_9BACI/3-91             ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...SSF....VW..Y....YAIFW...ILLM...VAWLI..RPKTNPKLRMAKALFLAVTRDRIAYCAID..........
Q1WR78_LIGS1/4-95                 ............fv--IVPDIKAEIKFFW..NIFLKDV.A.VLGL.VIF.ATM.LL.LQLF..P...EEQ....SK..Q....QYIFMglgFILA...IYLDL..RPRTNPGKRNYEVIWMLLLNR--------qpklfksy..
R3WMF7_9ENTE/4-92                 ..............YNIQEEIITKAKYWG..VVLSSDL.V.YMLL.LFQ.FAA.KF.REHV..V...PTL....GN..F....TVIVI...FLFG...LYWIL..PNASNSQKRNYHRLVLSITKNRQTYHP--ia........
K2GLQ4_9BACI/3-91                 ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...SSF....VW..Y....YAIFW...IILM...VAWLI..RPKTNPKLRMVKALFLAVTRDRIAYCAID..........
A0A856M596_9BACI/5-92             ............vs--VPENIQAKIQWNK..-LTVVDG.F.VIIG.SLA.VGY.FM.KGLV..Y...PYL....QI..P....FVLFI...VLAT...TFYLW..PCPDSPSKKIYEMTLMVFRKDSRTYKAQ-e.........
A0A437K413_9BACI/2-91             ..............YTNPKSTKQEIKLW-..AFYLVDI.G.IVVG.MLM.IAT.YV.KKVIplG...PGM....TM..F....YYILS...AAFG...MFLCA..KTPSHPTDRNYNILFYLFKMDRNKYHAIE..........
A0A176U332_9FIRM/3-92             ..............YHVTKDLKAEVKVSG..SLFLKDL.L.ILVL.YPT.IMW.FFtGGLV..A...DTL....KI..P....YIIYN...VLVI...LVLLQ..RPASNPGKQVWQVCVFLLTEDLQTYHM--ir........
B9EC73_MACCJ/10-100               ..............YTIPRDMKADILIIG..KTTLKDI.I.VIII.FVV.LGF.ML.ANFI..Dg.gPIL....TT..I....IVIIQ...FLVG...GIAIA..KPKTNPDKPMYLVIASMFRMDKNVYRSLD..........
A0A844LSW9_9BACI/3-91             ..............YEIPKEIKSKPKIVG..-LEMREL.V.IILIsSLL.LLT.VL.RELV..H...SLF....IL..F....YFGIA...IIGM...IYLFL..PSGNNPEKRNYESILLMFRHKKGVYHAMD..........
T0D3R2_PAES9/2-90                 ..............YIIPSEINSETKIFK..NVYLIDM.L.FMLV.AFV.LTM.SF.SSIV..N...PKV....VV..P....YYICS...FVLT...IFLVL..KSQTNPGLRNYKAIYLMIIRCRGTYQSLD..........
A0A7H8SAN8_9BACI/3-91             ..............YEIPKEIKAKPKILG..-LEMREL.V.ILLI.SSLlVLT.IL.RDLV..H...SVF....MM..P....YFVAV...IGFM...IYLFM..PSGHNPKKRHYESLILFFRHKKAVYHAMD..........
L5N6E4_9BACI/3-91                 ..............YKIPSEIGSELKINR..LFYLTDL.L.VVLI.LGG.IGF.TF.RYVV..H...SSF....VW..W....YAIFW...VLLM...VAWLI..RPKTNPKLRMAKALFLAVTRDRMTYCAID..........
A0A1H9I032_9LACT/5-92             .........rniet------LSPETKLTK..TLFLKDL.A.LFVL.III.LLA.PL.YLLV..Y...PPF....QI..P....YIIFI...SLFA...YKMVS..KPKTNPGKRYYQVLRLAFTKDSHYYH---mtt.......
S0KIP7_9ENTE/2-90                 ...........ftr---PNKISNEIKLLG..RYQLTDA.F.VVLL.ILF.FGMgNL.ADYI..Y...EPI....RL..F....FRLFL...FIMT...IFWLS..PSPFKPQSKNIGVLMDCLKKDTHTYF---pd........
A0A2L1FFS9_9BACI/4-92             ..............YNIPKEVTTELKINK..SLFLFDL.L.FIIS.LLI.FTM.IL.NIFI..H...PVL....QI..P....YYIFM...GIVG...LIMIW..RPHTNPKKRMYQVLLITMMRKKNTYCAID..........
A0A0K9H0Z6_9BACI/4-92             ..............YRIPKEISSELKINK..VLFLFDL.L.FIIG.LIV.LTL.IF.NNFV..H...NDL....RI..A....YYLFM...AIVG...IIMIW..RPSTNPKKRMYEVLLITIMRKRNTYCAID..........
A0A0E4CSZ7_9STRE/5-94             ..............YGVPRDIYAKVKIIG..LV-MADI.V.FVGG.SAV.AAV.SV.GTRI..F...PTS....QW..A....QLLAF...VILT...PLMCLylVLPTNGGKKNWHSIFLFFRRRRKRYVSL-n.........
W7CA43_9LIST/2-91                 ..............YTNPKNIKQEIKIL-..FFYFVDI.M.IVIG.GFI.VGV.GI.SKPL..H...LSF....GMtlF....LEILT...TLFA...LWLCV..RAPSHPNERNLSVLIHLFKMDRNH-----hhsie.....
A0A4Y9A8W4_9BACI/3-91             ..............YEIPKEIKAKPKILG..-LEMREL.V.ILLI.SSLlVLT.IL.RDLV..H...SVF....MM..P....YFVAV...IGFM...IYLFM..PSGHNPKKRHYESLILFFRHKKAVYHAMD..........
A0A366I1L2_9FIRM/2-91             ..............YKNPKNTRQEIKLW-..AFYLLDI.A.IVAG.MLL.IAN.NI.SKIIplS...PSM....QI..F....YYIFS...ACFG...VFLCM..KTTSHPIDRNLNILFYIFRMDRNKYHSID..........
A0A0M1V0S0_PAESO/2-90             ..............YIIPSEINSETKIFK..NVYLIDM.L.FMLV.AFG.LTM.SF.SSIV..N...PKV....VV..P....YYICS...FVLT...IFLVL..KSQTNPGLRNYKAIYLMIIRCRGTYQSLD..........
#=GC seq_cons                     ..............YpIPp-IpuEhKl.t..hlaLpDl.h.lllh.hhh.lsh.hh.pthV..a...ssh....hh.......ahIhh...hlls...lhhlh..+stsNPp+R.apslhlhlp+c+tsYpuhc..........
//