#=GF ID DUF5620
#=GF AC PF18522.5
#=GF DE Domain of unknown function (DUF5620)
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF06401
#=GF GA 25.00 25.00;
#=GF TC 25.30 40.90;
#=GF NC 24.00 21.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 27298375
#=GF RT Complexity of the Ruminococcus flavefaciens cellulosome reflects
#=GF RT an expansion in glycan recognition.
#=GF RA Venditto I, Luis AS, Rydahl M, Schuckel J, Fernandes VO,
#=GF RA Vidal-Melgosa S, Bule P, Goyal A, Pires VM, Dourado CG, Ferreira
#=GF RA LM, Coutinho PM, Henrissat B, Knox JP, Basle A, Najmudin S,
#=GF RA Gilbert HJ, Willats WG, Fontes CM;
#=GF RL Proc Natl Acad Sci U S A. 2016;113:7136-7141.
#=GF DR INTERPRO; IPR040753;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is a domain of unknown function predicted to be a
#=GF CC carbohydrate binding module [1].
#=GF SQ 34
#=GS R7H2B1_9FIRM/454-590 AC R7H2B1.1
#=GS R7FB62_9FIRM/227-338 AC R7FB62.1
#=GS R5UZN8_9FIRM/237-348 AC R5UZN8.1
#=GS R7H2B1_9FIRM/55-183 AC R7H2B1.1
#=GS R7FB05_9FIRM/480-649 AC R7FB05.1
#=GS R7A7A1_9FIRM/233-369 AC R7A7A1.1
#=GS R7FB05_9FIRM/294-460 AC R7FB05.1
#=GS R7MHV4_9FIRM/1-105 AC R7MHV4.1
#=GS U2LZH0_9FIRM/112-226 AC U2LZH0.1
#=GS R7GXD2_9FIRM/186-297 AC R7GXD2.1
#=GS U2LMS4_9FIRM/324-501 AC U2LMS4.1
#=GS R7GYB9_9FIRM/225-336 AC R7GYB9.1
#=GS R7A7A1_9FIRM/394-505 AC R7A7A1.1
#=GS U2LMS4_9FIRM/89-220 AC U2LMS4.1
#=GS R5UXX9_9FIRM/320-512 AC R5UXX9.1
#=GS U2KNT3_9FIRM/317-426 AC U2KNT3.1
#=GS U2LQF4_9FIRM/86-196 AC U2LQF4.1
#=GS R7MHV4_9FIRM/157-266 AC R7MHV4.1
#=GS R5UXX9_9FIRM/535-671 AC R5UXX9.1
#=GS A0A1K1NYL1_RUMFL/81-194 AC A0A1K1NYL1.1
#=GS U2LZH0_9FIRM/251-362 AC U2LZH0.1
#=GS R7FB76_9FIRM/1-106 AC R7FB76.1
#=GS A0A1K1NNQ5_RUMFL/661-771 AC A0A1K1NNQ5.1
#=GS R5UXX9_9FIRM/72-201 AC R5UXX9.1
#=GS R7GYB9_9FIRM/86-200 AC R7GYB9.1
#=GS R7FDM0_9FIRM/241-350 AC R7FDM0.1
#=GS R7FB05_9FIRM/77-195 AC R7FB05.1
#=GS R5UZN8_9FIRM/98-212 AC R5UZN8.1
#=GS U2LMS4_9FIRM/522-694 AC U2LMS4.1
#=GS R7H2B1_9FIRM/270-432 AC R7H2B1.1
#=GS R7A7A1_9FIRM/50-162 AC R7A7A1.1
#=GS R7FB62_9FIRM/88-202 AC R7FB62.1
#=GS A0A1K1NYL1_RUMFL/218-320 AC A0A1K1NYL1.1
#=GS R7H2K0_9FIRM/535-590 AC R7H2K0.1
R7H2B1_9FIRM/454-590 .............kt---GDNAEVLF.SDYGIQYDHt....lDVYAILFKISSTT...DISKLVVGLGTSVRNTCPAKTS............................DYW..YQ..AKADTLIVSed.................................aaSHTYDLMWIIPGDVAEslqhn....adkhmnYISTEQPkDNFKLGFWYGGAGETE..........aSSVTLKDATIY.....
R7FB62_9FIRM/227-338 ..............d-EAAKMADISL.SDL-IGKDD......TLQTVTFDVSSDG...SLGKFTGAFGVSVKEGADCATD............................KGW..YQ..SPNVCVFTD.....................................ASNLSLTWIVPDEVKA...............EID--QG.GKVSLGYWWSDQ----...........ASITLNKVSVR.....
R5UZN8_9FIRM/237-348 ..............s-DTDKQVKLPL.SDF-IDKDD......RLQTVTFDISSSG...SLGKFTGAFGVSLTSGCDAETD............................KNW..YQ..TGNIVTFTQ.....................................DSSVSLTWIVPESIQD...............YID--PT.GDLMLGYWWSDQ----...........ATVTLNKVSVR.....
R7H2B1_9FIRM/55-183 ..............e-EVTNKDEVSYrGDVKDLATS......GLTSLQFNFSASE...EVSQFQYYFGIALKDEP-----............................--W..WA..GSTMDGTVQpegtgen......................gafsctpyASKFSVVVDVSNLDIG...............YDDTYGE.KKFEIQNCYTEADGGK..........eIPIKLESIVVN.....
R7FB05_9FIRM/480-649 .............es--VGKSVSVNY.ADFGMKYEKt....aDVYAVLFDVTTDM...DVNQMVVGAGTSVLSKLTAATS............................ECW..YQ..TDDANENGKlvlvnwepttagsrpd.....psdtdaevkpyedakgKNKYTFMWVMPGAVANgimegangtmskatnYVSTEQEgDHVDLGVWYAGLGEST..........sKKYTIDNVTAY.....
R7A7A1_9FIRM/233-369 ..............g-DPLNSHKITY.KDFGISDLSd....lTLESFTFILESDS...DMGTVMYGGGMNVAAQSPADTEyin......................gkeGFW..YN..DHGPEDETDygfeigr.......................gttldsvGKYQEVTWEMPETVRE...............NATTAGN.DAVSIQYWYGDN----...........ESIKLTGATCT.....
R7FB05_9FIRM/294-460 .............gl--PLNSHKFTY.SDFGLAPGKnassdvKIKSLSVTLKTEE...NLQRIMYGGGLNVEGHSVADTEyakylag.............megknelsGYW..YN..DIGPEALAAaeeagakfgvt..............igggtdlakqdiGNYFTVTWDVPEEVIP...............YATVKPT.DQISFQLWYGQVVADTyt.......klDKATIVDATLT.....
R7MHV4_9FIRM/1-105 ...............-----MIGFDW.ADFDIPAGE......KVTKVEVNVSASS...TIGKWQGAFGSSTSVSP-----............................DYW..TQ..SDEMEQKIN.....................................GTSGTITWNIDSATSE...............IIQTLYG.GQLKFGIWWVDC----...........GTFTIDSITAY.....
U2LZH0_9FIRM/112-226 ..............s-DTTNNYKAKL.DNF-IQEGD......VVQSFTFIVYSADgssSLGDFKGGYGVSVKDGCASATD............................AGW..YQ..AADFEQSQN.....................................SAYAEFTWNVPAEIQT...............EID--PS.GEVLFGHWWSNV----...........QQVKLSSIVCT.....
R7GXD2_9FIRM/186-297 ..............p-DDDKMIGWNW.SEFGLQKGE......LVKRVDVKISVPS..gTIGKWSGGFGSSTTVKP-----............................DYW..-T..MEEMEDTYN.....................................TQSAIISWTVPAATAK...............TFQTQGNySYLKFGTFYTTNG---...........SVFSVDSVTVY.....
U2LMS4_9FIRM/324-501 .............gl--PLNSHKFTY.GEFNFIPGAtvasnaKVKSLSVTIKLDDesaNVNRFMYGGGLNVKYKSLADTEyakeqaglkg.......gsgeggvaktvGYW..YN..DVGAETLAEcteagvkwgngegd.........fkvgggtdlakqemGSYFTVTWDVPEQVVD...............CETLAEK.SQISFQLWYAALKGGK..........fVDCSIVSAAL-t....
R7GYB9_9FIRM/225-336 ..............d-ESAKEAKISL.GDL-ITEGD......TLQTVTFDVSGGG...SLGKFTGAFGVSVAEDSKAATD............................KGW..YQ..SSNVVLFTD.....................................SNAVSLTWIVPDEVKA...............DIQ--AG.GEVMLGYWWSDQ----...........NPVTLTNVSVR.....
R7A7A1_9FIRM/394-505 ..............d-DTTNAAHIDL.ADLDLTNND......TIQAIKFTVSAGT...DIGKFVGAFGISVDETLD---E............................TMW..YQ..GNNFVIQDA.....................................GKNIEIMWILTPTVKN...............NVNVEY-.GNTMLGFWYGNDA---...........DTITLDSVDVY.....
U2LMS4_9FIRM/89-220 ............kaa---TDAYTSFT.DTKGKSPADic..gdSITTLQFNLKSDQ...MVTDFSYYFGASDTKAN-----............................GYWwgFE..KTDSKGAIKct.................................pyAKEFSVVVELPSSVAK...............ELTSNKN.AKFQFQNCYTGLIDEEdqst...rtqdASIELVSITVN.....
R5UXX9_9FIRM/320-512 ..............g-DPLNSHKFSY.DDFGIGSGDet.tkiTPEALTVVMRAKDn.qNVTRIMYGGGLNVEAGTPADTEkakakigrdeagnvtddslagfkkdgnaGYW..YN..DIGADSYDDvaknlenvgykvgspdt..englvqiqngkdlkeqsfGDYVQVTWDVPEDVKQ...............YADAASG.KTISFQLWYGEIEAEEyt.......plESLDIDSAMLT.....
U2KNT3_9FIRM/317-426 ..............d-PKEGMIGWKW.ADFGITNSN......VVKKVVVNVSSDK...EIGTYNYMFGSSTQKAP-----............................DYW..TQ..TTQENKTL-.....................................GKSGEFTWDITKTVDA...............TIQKEYD.GSLKFGAWGDGTY---...........EDFTVDSVVIY.....
U2LQF4_9FIRM/86-196 .............pa--GDKMLGWKW.SDLGVPAGE......KVTKVEINLSTSK..kQIGKWQGAFGSSTSVAP-----............................DYW..TQ..SEDMEQTIS.....................................GKTGSIVWDVDSATSA...............IIQTQYG.GELKFGVWWIDC----...........NKFTIDSITVY.....
R7MHV4_9FIRM/157-266 ..............p-ENDKMIGWEW.SEFGIPTGE......KVKKVEINISASS...TIGKWQGAFGSSTSVSP-----............................DYW..TQ..SDEMEQTIN.....................................GKSGAITWNIDSATSE...............IIQTLYG.GELKFGIWWIDC----...........GTFTIDSIKVY.....
R5UXX9_9FIRM/535-671 ..............k-TGDDPLEILY.SDLGMTYETt....aDVYAIEFTLDSKV...DARQLVLGNGTTVVDKAS----............................DYW..YQ..AGSIALVKSd..................................dkNHEYTYMWIMPADVANvtlgedg.timsllnKVSTEKEgDHFSLALYYADNNDGKe.........vTSVNLKSVSAY.....
A0A1K1NYL1_RUMFL/81-194 .............ae--GSNTIKFPL.ADL-IEEGD......RIESFTFTVYAGDg.gNIGEFKGGCGISVDDKCPAATT............................KGW..YQ..SGDFSAPTE.....................................GSYGEITWNVPEELKD...............YIH--EG.GEVLFGYWWGNC----...........ESLKIDNVVCR.....
U2LZH0_9FIRM/251-362 ..............d-EAAKTAKIAL.SDL-IGAED......TLQTVTFDISSTG...ALGKFTGAFGVSVDKNADCATD............................AGW..YQ..TKNVCVFTD.....................................SSSLSLTWIVPDDVKE...............SID--PS.GDVMLGYWWSDQ----...........PSITLNNISVR.....
R7FB76_9FIRM/1-106 ...............-----MIGWAW.KDLGVKSGD......KISKVEINITAKS..gEIGKWQGAFGSSTSVAP-----............................GYW..TQ..SDDMTQTIN.....................................SKSGTITWDVDAATSS...............IIQVDYD.GQLKFGIWWIDC----...........TQFTIDSIKVY.....
A0A1K1NNQ5_RUMFL/661-771 ..............g-DDERMIGFSY.KDFDIPSNA......KITEVQVDISANK...NIGKYVGQFGTSTTDSAN----............................GYW..AM..GDEITQSIS.....................................GNSGTITWKVPSDIAS...............IIQTEYG.GEIKFGVWWIDC----...........DDFTIDAVR--lk...
R5UXX9_9FIRM/72-201 crytsylkddaykny-----------.-----SSSN......KITSLQFNFTAKE...QIKKFSYWFGINVTSAY-----............................GDW..YSpaEEAIEGYIDyg................................tseSSDFTITIDLSKVEVNyyqle.....nwavgQW-WNEE.KRFDMQNCYAETVSGK..........eVPVTLKSVTVN.....
R7GYB9_9FIRM/86-200 ..............r-DKTNTYKANL.DQF-IQDGD......QVQSFTFIFYAADgssNIGTYKGACGVSVKDGSSAATD............................KNW..YQ..SDDFSQEAN.....................................GSYIELNWTVPAEVQK...............DID--PS.GQVLVGYWWGDV----...........QQVRLDSIVCT.....
R7FDM0_9FIRM/241-350 ..............n-PKEGMVGWKWdEDLGVTDAT......KVIKVEINLSADE...TIGDLSYKFGSSTSVDP-----............................KYW..TE..SKQVDDTFN.....................................DTKAVLSWDIDKATAN...............IIQTEYD.GTLKFGAW-GGL----...........DDYTIDSVVVY.....
R7FB05_9FIRM/77-195 ............tpf---TDTKGKGI.KDL---FGT......GIKTFQLNFKSDK...LVTNFSYYFGCSADKAHS----............................YYW..DI..GEAIACTPY.....................................ATEFSVVIEVPSYADL...............----SNN.GKFQVQNCYTGLAEQDpadnsvktytnESITLVSIEA-n....
R5UZN8_9FIRM/98-212 ..............r-DADNTYKAKL.ENF-VQDGD......VIQSFTFIFYAPDgvsNMGTYKGGCGISVKADSATATD............................KNW..YQ..SDDFEQSVN.....................................GAYAEITWNVPTDVAA...............DVD--AN.GDVLIGYWWSDL----...........QQLKLSSIVCT.....
U2LMS4_9FIRM/522-694 .............em--TGTAAEIPY.ADFGMKYEKt....aDVYAVQFDVTTDQ...EANQVLVGAGTTMLEKAGFP--............................DNW..FQ..SDDLFKNEGlnsttpamlywekstagnrpdsnddtladeaykdasgTKTYTYMWIMPPSVAEgirqeetgnllnalnSVDTESEdAHLSFGVWYAGLGSKE..........sSKYTINNVTV-f....
R7H2B1_9FIRM/270-432 ..............g-DPLNSHEMKY.SDFGIRAGEsdaytvTIDSVSATIKSKV...PLKRFMYGGGLSVINGSPADLEaakvaa................gvkkqgGYW..YN..DMGTEELEKykdvpfeitps...............egvdirdkdqlGSYFQVTWDVPAAVKE...............YTTSDSS.SKISFQYWYGEEDAEQyt.......kcDSVTLVDAVVT.....
R7A7A1_9FIRM/50-162 ..............k-EGDNTYTVNT.ASL-CGSGE......TLTSITCVFEAPI...SSGSFSGGLGIGVTKDYS---P............................EYW..YQ..GESFKQSFT.....................................SSTFTVVYEIPKEVQP...............YVN--TT.ATTNIGMYYCGNSATT...........GSVKLISVT--gn...
R7FB62_9FIRM/88-202 ..............s-DDANNYKAKL.SNF-IEDGD......VVQSFTFIVKAADgssNLADYKGGYGISVKDSCASATD............................KGW..YQ..AADFEQSLN.....................................SSYAEFTWNVPSEIQS...............DID--PA.GEVLFGHWWSGV----...........QQVQLTSIVCT.....
A0A1K1NYL1_RUMFL/218-320 ....sdednrvhipl-----------.-DF-IPEGM......IPEVVTFNVSTTG...SFGKFTGAYGISSTAGE-----............................---..FQ..SGDVSIFTD.....................................SDNLQLTWFVPDKAKG...............CME--KD.NELLLGYWWSDQ----...........PTLTVDKVEV-k....
R7H2K0_9FIRM/535-590 ..............p-ADDKMIGWNW.SDLGVSAGE......TVQKVLINVSTDN..dKVGKWQGAFGSSTTVAP-----............................---..--..---------.....................................----------------...............-------.----------------...........-----------dyflp
#=GC seq_cons ..............t..sspthphsh.uDhtlpsuc......plpslphslsuss...slGcapsuaGsSlpsss.................................thW..aQ..usshpphhs.....................................usphsloWplPsslts................lp...s.uplphGhWaust...............sslolsulslh.....
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