#=GF ID   DUF5622
#=GF AC   PF18533.5
#=GF DE   Domain of unknown function (DUF5622)
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF04212
#=GF GA   25.00 25.00;
#=GF TC   31.20 39.60;
#=GF NC   23.40 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   24875358
#=GF RT   Structure determination of archaea-specific ribosomal protein
#=GF RT   L46a reveals a novel protein fold.
#=GF RA   Feng Y, Song X, Lin J, Xuan J, Cui Q, Wang J;
#=GF RL   Biochem Biophys Res Commun. 2014;450:67-72.
#=GF DR   INTERPRO; IPR041043;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a domain of unknown function found in archaea-specific
#=GF CC   ribosomal proteins such as L46a which is suggested to directly
#=GF CC   bind to rRNA in the ribosome [1].
#=GF SQ   23
#=GS W7L5Z8_9CREN/3-67      AC W7L5Z8.1
#=GS A2BIX8_HYPBU/3-67      AC A2BIX8.1
#=GS G0EDQ0_PYRF1/3-76      AC G0EDQ0.1
#=GS A0A2T9WTC1_9CREN/3-67  AC A0A2T9WTC1.1
#=GS A0A650CN63_9CREN/3-69  AC A0A650CN63.1
#=GS D5U038_THEAM/3-76      AC D5U038.1
#=GS F4B4Q0_ACIHW/2-64      AC F4B4Q0.1
#=GS A4YHI2_METS5/3-67      AC A4YHI2.1
#=GS A0A348B388_9CREN/3-64  AC A0A348B388.1
#=GS L0ABU1_CALLD/3-67      AC L0ABU1.1
#=GS I3TCE2_THEC1/3-76      AC I3TCE2.1
#=GS H2C8H7_9CREN/3-67      AC H2C8H7.1
#=GS Q05E72_AERPE/3-67      AC Q05E72.1
#=GS D9Q2T6_ACIS3/4-67      AC D9Q2T6.1
#=GS A0A2T9WXY0_9CREN/2-73  AC A0A2T9WXY0.1
#=GS A0A031LPY1_9CREN/2-65  AC A0A031LPY1.1
#=GS F9VNZ7_SULTO/3-71      AC F9VNZ7.1
#=GS B8D2M1_DESA1/8-81      AC B8D2M1.1
#=GS A0A510E296_9CREN/2-73  AC A0A510E296.1
#=GS A3DP45_STAMF/13-89     AC A3DP45.1
#=GS A0A0V8RX97_PYROC/3-67  AC A0A0V8RX97.1
#=GS E0SQD0_IGNAA/3-67      AC E0SQD0.1
#=GS Q4J953_SULAC/2-68      AC Q4J953.1
W7L5Z8_9CREN/3-67                 ....LKHKKYVYIDTG.KG.......F.YVKARLL........KNRDE.....-NSAERYVLLNITPKTRPRKASVLKLDNLPLEIKEKVSK..
A2BIX8_HYPBU/3-67                 ....GKHGKYAYVLRN.DG.......W.YVKVRVL........KSREE.....-NDPARYIVVGPKRKDVPPTYPVLREDDVPEEVKKQLY-t.
G0EDQ0_PYRF1/3-76                 ....GKHKKYVYVLRE.DG.......W.YVKVRVLgld.kkefKKHGK....lPEDPSKYIPVGPKVKNPPSTYAIVPIEKLPEEAQRKVRE..
A0A2T9WTC1_9CREN/3-67             ...a-KHGKYIYVEIE.KG.......K.IAKIRFF........KGIEE.....-SKEEAYLITGKIVKKIPRKAKVKKLDDLPEPVKEKLR-v.
A0A650CN63_9CREN/3-69             ....LKHQKYQYVQIS.SD.......H.FVKIRVF........KSRLE....eSNPPDAYLILNRLVKRLPRKAKVIKVEDLPVEIRDKL--gi
D5U038_THEAM/3-76                 ....LKHGKYVYVDRL.DG.......S.YVKVRVLnir..fhkKTEEKi...dVTNPTRYIVTGTVVSKPPARAIVISIEALPEEVRNLVR-s.
F4B4Q0_ACIHW/2-64                 ....LKHKKYLYVDTG.-K.......Y.FIKVRVL........KNRDE.....-NSPDSYIVVSKNIKK-PRNALVKKLEDLPIEVRDKISK..
A4YHI2_METS5/3-67                 ....LKHEKYVYVELG.KS.......R.YAKLRVL........KNRDE.....-NSPERYIVLNKLVPKKSRHVKVLKTDDLPLEVREKLK-a.
A0A348B388_9CREN/3-64             ...t-KHGKYIYVETG.ER.......D.YVKIRVL........KGREK.....--ETEKYVMTSVRVNRVPRGAQRVSKESLPAEVKAL---l.
L0ABU1_CALLD/3-67                 sknt----KFAYIYMGrKK.......G.YYKVRLF........NSKPE.....-EDPDRIIVIGK-FKKPELGYRIIKKEELLEVVREKVEK..
I3TCE2_THEC1/3-76                 ....LKHGKFIYVERA.DG.......F.YVKVRLLkvrfgkkgKS--Sg...dFNNPQNYVVLPFKTRKPPASAVVVKGQDLPDEVRRLVD-a.
H2C8H7_9CREN/3-67                 ....LKKGKYVYVELD.KS.......R.FAKLRVL........KKRDE.....-KSPDRYIIINKTFVRRPRSATVVKLEDLPLEIKDRLT-n.
Q05E72_AERPE/3-67                 ....GKHGKYVYVKRG.DG.......W.YVKVRVF........KNRPQ.....-DSPERYLIVGPKRREAPITFQVLEEDELPEEVRRALY-l.
D9Q2T6_ACIS3/4-67                 .rrn----KVVFIFMG.KG.......KgYLKVRLF........RKRKE.....-EDPDRVVVLGKVEK-PLPGYQVIRLEELEAAVREKLEK..
A0A2T9WXY0_9CREN/2-73             ....LKHKKYVYVEVT.KEegkkkriY.YVKVRVL........KSRDN.....-SDPQKYIVLDLVRTGKPRTAKVLSVDVLPTDVKQLI--ls
A0A031LPY1_9CREN/2-65             ....LKHGKYIYVNVG.NG.......Y.YIKVRIL........KKRDE.....-NSPDRYIPIFRTSRR-VRKAKVVKLDDLPVEVRDRLSK..
F9VNZ7_SULTO/3-71                 ....LKHGKYVYVQLD.KN.......K.YVKMRYL........KSYEKa..ekANDVNAYIILGKIVTKASRKAKILKREDLPVEVRDKLP-k.
B8D2M1_DESA1/8-81                 ....LKHGKYIYVKRS.DG.......W.YVKVRVLni...rfgKKQEEg..idVNNPTRYIVTGFKTKVPPITAIVISEDALPQPVRSLVN-e.
A0A510E296_9CREN/2-73             ....LKHDKIIYIEVK.KGtneketkF.YVKARSF........KSKDY.....-NSPEKYILLNSRKEKPPRNATIVKVDDLPLEVKEKL--lk
A3DP45_STAMF/13-89                ....LKHGKYIYVERK.DG.......W.YVKVRVLnir..lkkKDKKEkysfdINDPEKYLVLQVKTRKPPFKAQIMREDDVPDEVKKALYQ..
A0A0V8RX97_PYROC/3-67             ....GKHGKYAYVLRS.DG.......W.YVKVRVL........KSRKE.....-DDASKYIVVGPKRRDVPPSFPVIREDEVPEEVRRQVYE..
E0SQD0_IGNAA/3-67                 ....LKHGKYVYVKRS.DG.......Y.YIKVRVL........KSRGD.....-EDQDKYIVIGPKTHKVPPTATIIREEQLPEKIREKLY-a.
Q4J953_SULAC/2-68                 ....LKHQKYVYVDIGdQK.......K.FLKVRFL........KSRSE.....NNNPEAYVILDKISIKLPRNAKVIKYEDLPAEVKDKLK-l.
#=GC seq_cons                     ....LKHsKYlYVchu.cG.......a.YVKVRVL........KsRcE......ssP-+YIllshps++sPtsApVl+h--LPtEV+c+l....
//