#=GF ID   DUF5625
#=GF AC   PF18539.5
#=GF DE   Domain of unknown function (DUF5625)
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF03678
#=GF GA   26.90 26.90;
#=GF TC   27.40 27.50;
#=GF NC   26.70 22.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0202
#=GF DR   INTERPRO; IPR041008;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a domain of unknown function found in proteobacteria.
#=GF SQ   44
#=GS A0A1R4HB83_9GAMM/47-182  AC A0A1R4HB83.1
#=GS A0A1H1B530_9GAMM/45-199  AC A0A1H1B530.1
#=GS T0PAD7_PHOTE/35-122      AC T0PAD7.1
#=GS A0A2R4CGS0_9BURK/37-179  AC A0A2R4CGS0.1
#=GS W1J357_9GAMM/35-168      AC W1J357.1
#=GS W1IRH9_9GAMM/52-189      AC W1IRH9.1
#=GS G3IQH4_METTV/47-177      AC G3IQH4.1
#=GS Q7N8T0_PHOLL/35-168      AC Q7N8T0.1
#=GS T0P5S2_PHOTE/20-92       AC T0P5S2.1
#=GS A0A4R5M4P9_9BURK/36-174  AC A0A4R5M4P9.1
#=GS D2U2U5_9GAMM/35-168      AC D2U2U5.1
#=GS N8W015_9GAMM/32-177      AC N8W015.1
#=GS A8EV79_ALIB4/40-226      AC A8EV79.1
#=GS J3HHK6_9BURK/42-183      AC J3HHK6.1
#=GS A0A1G8JI88_9RHOO/70-183  AC A0A1G8JI88.1
#=GS A0A848FIZ1_9BURK/32-175  AC A0A848FIZ1.1
#=GS T0NY62_PHOTE/35-168      AC T0NY62.1
#=GS Q7N8S9_PHOLL/35-168      AC Q7N8S9.1
#=GS A0A0S2DIQ2_LYSEN/32-163  AC A0A0S2DIQ2.1
#=GS D1B1Q7_SULD5/25-155      AC D1B1Q7.1
#=GS Q9P9W4_XYLFA/44-189      AC Q9P9W4.1
#=GS Q7N8S5_PHOLL/35-168      AC Q7N8S5.1
#=GS D2U2U4_9GAMM/35-169      AC D2U2U4.1
#=GS D1B1Q1_SULD5/24-185      AC D1B1Q1.1
#=GS Q7N8S6_PHOLL/35-168      AC Q7N8S6.1
#=GS G3IQH3_METTV/48-176      AC G3IQH3.1
#=GS A0A0Q8RIB2_9BURK/34-177  AC A0A0Q8RIB2.1
#=GS Q7N8S7_PHOLL/35-168      AC Q7N8S7.1
#=GS D1B2F0_SULD5/24-185      AC D1B2F0.1
#=GS W1JA23_9GAMM/1-89        AC W1JA23.1
#=GS A0A497XLS7_9PROT/46-190  AC A0A497XLS7.1
#=GS Q7N8T1_PHOLL/35-168      AC Q7N8T1.1
#=GS A0A0D7P371_9BRAD/35-177  AC A0A0D7P371.1
#=GS A0A1G8JGX4_9RHOO/69-183  AC A0A1G8JGX4.1
#=GS A0A2T5HA34_9PSED/34-197  AC A0A2T5HA34.1
#=GS I4MVY4_9PSED/25-152      AC I4MVY4.1
#=GS G3IQH2_METTV/8-126       AC G3IQH2.1
#=GS Q7N8S8_PHOLL/36-171      AC Q7N8S8.1
#=GS A0A011R4N0_ACCRE/44-182  AC A0A011R4N0.1
#=GS W1INB7_9GAMM/1-131       AC W1INB7.1
#=GS A0A0K1K0X0_9BURK/38-172  AC A0A0K1K0X0.1
#=GS A0A2L1GQ90_9DELT/33-159  AC A0A2L1GQ90.1
#=GS D1B1Q4_SULD5/25-157      AC D1B1Q4.1
#=GS A0A426VH48_9BURK/41-182  AC A0A426VH48.1
A0A1R4HB83_9GAMM/47-182             .........d-TPIALHKAGNVIETDFKIEQD..DKISLKLRFFVNDQ.PGDRNR..............LLDFL.......G.............................REA.GIgfs.....vpqTVTVPLKIKIIK...YTDVKKSVILNKTYT...T...TG.LV.SS.GETTLD.....................................RLIDKLSITS.G.NYRIR.IETIKDFPQLIDTKVQFKLYY..................
A0A1H1B530_9GAMM/45-199             .........a-IPFSINKAGNVAKIDFQA-QP..GAVDLKKTYMVKLT.FDRAQNr............dPLSLL......eG.............................R--.PP...........RTLLPIKAKVTRi.dGNSMEAVTIMDNSQF...L...GN.I-.--.DIEKYPgttpenpredvv............yaflygstgtqgdICIARFNLSSyG.HYQVE.IETVQDQPIFDNVKSSLTI--ee................
T0PAD7_PHOTE/35-122                 ..........YKPIDVSHSGQSVKIDFEISKK..GNYQFALLFDKGDD.YEEMKR..............RLELF.......G.............................DID.KD...........GIITPVSLQIVK...----DGKVFFDEKIN...A...GG.YA.G-.------.....................................----------.-.-----.---------------------dvpsit............
A0A2R4CGS0_9BURK/37-179             .........a-IPFAVRTGGETAHTDLRIAQQ..GIYRFGLTFQAVNV.-RDSSEv...........yaLLDLM.......Gd..........................aeN--.-PypssaspppnyGVPLSLSLRIER...LEPGPVAVVFDRTTD...Q...VQ.RY.AG.FGGRFL.....................................KKIGDVTLDR.G.VYRVT.VKNLRPAAQLSNLSVHIHIN-k.................
W1J357_9GAMM/35-168                 ..........YKPIDITRSGQSVKFDFEIKNK..GNYQFALLFATTDD.SDEMVR..............RFELF.......G.............................RID.KS...........GVITPVSLRIVK...----DGQIFFDNKIN...A...MG.SE.GG.SLFDYEersi.............................ntavREIKTFFLPP.G.LYSAV.ITTLEDVPAFNGIESFVEFTY..................
W1IRH9_9GAMM/52-189                 ........kl---VDVTKAGQSVTFDFEIPQE..GGYQFALLFDKGND.YDEMLR..............RLRLF.......Gsk........................fygSID.EE...........GGITPVSLHLVK...----DGQFFFDEKIN...A...GG.NG.GG.LSFYYEekyv.............................naaiRGIKSFSLSP.G.RYSAV.ITTLDDVPAFYGIESFVELTY..................
G3IQH4_METTV/47-177                 ..........KMPIALHQAGSVAEADFEIAQD..DRVTLQLRFFVNDQ.PDDRKR..............LLAFL.......G.............................GFG.ET...........KTSIPIKVRITK..hISPKEDLAILEKTYP...A...TK.LA.GY.GAKELN.....................................RLIDDLTIKS.G.KYRIR.LETIEEFPELSNTKVEFGMYY..................
Q7N8T0_PHOLL/35-168                 ..........YRPIDVSKSGQSVKIDFEISKE..GNYQFVLLFATTDD.YDEMAR..............RFELF.......G.............................RVY.KN...........GVITPVSLHIVK...----DGKIFFDKKIN...A...AG.SE.GG.RAVNYEerri.............................ntavREIKTFSLPP.G.RYSAV.ITTLEDVPVFNSIESFVEFN-h.................
T0P5S2_PHOTE/20-92                  .........r-KPIDVLHSGQSVEINFELSKSqaGNYQFALLFEKGRS.YAEMER..............RFELF.......G.............................SID.KD...........GVITPVLLRLVK...----DGKVFF-----...-...--.--.--.------.....................................----------.-.-----.---------------------..................
A0A4R5M4P9_9BURK/36-174             .........f-LPIDASRSGSSVSTDVQVTEG..RLYIFYLIFHYKNE.-EQRKR..............LAVLV.......Gdggr.....................latgEYA.HP...........GIVQSVHLTLTT...-TAESASIDVDRNVQgiaA...HE.LG.AN.LSGAYD.....................................RKIYAGVLRP.G.LYHMK.ITILQGKREFEDFESAISV--gv................
D2U2U5_9GAMM/35-168                 ..........YRPLDITRAGQSVAVEFEIKKE..GGYLFALLFDKGGD.YEEVLR..............RLELF.......R.............................GVN.DT...........GVIIPISLRIVK...----DGQVFFDEIIN...T...KG.TD.GG.QAFYYQkrrl.............................ntavRKMKILSLLP.G.HYSVV.ITTLEDVALFNGIESFAHVSY..................
N8W015_9GAMM/32-177                 .........n-LPIDLTHTGALATTEFKINVP..KSYHLSLTVEFESA.QKRVDDl............vVGNTF.......Nqycdgt................ikynnipI--.-Ek........rkELGQPITLQVIV...RKSKNHEIVFNQQFQ...S...LC.ST.GHdGKNQSY.....................................RSIGWIPLSQ.D.LYVIE.VVNLQPHNHLKNVKTTLS---lna...............
A8EV79_ALIB4/40-226                 ........ke---IDVEKAGVVADFDIDISEP..EYYEFNFNYISITE.EYKISQenfkkgiktesdkiRKDIV.......G.............................DEY.ENk.........kGTKIVLKLTITPl.sLDKSENIFSLGSRYT...EdraKN.LQ.VG.KAMEYTmdlseifantyksycfdskksewkkgdvkkcrylsagKLITEIVLSK.G.KYHIK.LENLEDVPEIKKIKTT-----lldiy.............
J3HHK6_9BURK/42-183                 .......sla---FPLRQGGEQIDFLVRVKDL.eRAYQFNLIFVERDE.WPDDKKe...........hlRQMYR.......G.............................QGM.DDg.........eSPPSPVRLRIRIdsaGRHKGRPVHIDKLFS...G...RS.PF.YG.QRMT-Dnei...............................wraQNIHAAKFEP.G.IYRVR.VDNLAPAPQLD----------fetrflfe..........
A0A1G8JI88_9RHOO/70-183             .......dpr--------------------QD..WMMYLAFLFISGDI.-DDGRR..............VKKIA.......G.............................SPR.GD..........iGVPVSLKIKITA...RESSDARPVYEKSIE...N...EPvVV.AA.GNGRIH.....................................RIVDGVLLLP.G.KYRLE.VESVDDIPALVLENIEFAISY..................
A0A848FIZ1_9BURK/32-175             ........de--PIALSREGSTITREFEAPVD..LKYPLNIDFEFEST.QARLDDs............iVGYRF.......Dancwgn................kryddipE--.-Rqr......eglGRPMPFRVMIRH...--AADRAVVLDRVFD...S...LC.IT.SH.RDNLKT.....................................RTIGWLELRR.G.QYTAE.VTNLEAQAGLEHVVT------rvslv.............
T0NY62_PHOTE/35-168                 ..........YRPIDVSHSDQSVKIDFEISKK..GDYQFALLFARGHG.HDEMNR..............RDELF.......G.............................SIH.DD...........GVTTPVSLHLVR...----NGQVFFDEKIK...A...GG.YD.GG.HSFDYEertv.............................ttavREIKTFSLPP.G.RYSAV.ITTLEDVPEFDGIESFVEFTY..................
Q7N8S9_PHOLL/35-168                 ..........YKPIDVSKSGQSVKIDFEISKT..GNYQFVLLFATGDD.HDEMER..............RFKLF.......G.............................SIY.DD...........GVTIPVSLYLVR...----NDKVFFDEKIN...S...GG.YD.GG.QSFYYEerrv.............................ntavREIKTFSLSP.G.RYSAV.ITTLEDVPAFNGIESFVEFAY..................
A0A0S2DIQ2_LYSEN/32-163             ........da--PIAVA-SGGALDARIRLRVR..DSYRMQLVFLIPPD.--GRER..............LRNLLaepvprgG.............................PPV.SE...........GVVVPLRWSLSE...--ADSGRVVAQGEPR...T...EG.LD.AW.NSDMFW.....................................REAASFAAKP.G.WYRLR.VQATRPVPELAGVTTLIN---vgl...............
D1B1Q7_SULD5/25-155                 ..........KMPIDLSKAGNVTETDIRIDEK..YSVYVELYYDYRKQ.KISGDRyg..........eiIDKYF.......G.............................R-H.KL...........FPIFPIKLTVLK...YEKTGTTMVVDKIYY...T...NS.L-.--.GRTYSS.....................................REIDEFKLQE.GsKYHIK.VETVEDYPELAELNVEVVIGY..................
Q9P9W4_XYLFA/44-189                 .........i-LPFDLKKVGETYSFDVNLGGPltCSLDVKIFIAAPNK.WSRLLDknt........eieEEMRFyd..llgG.............................SKL.INhew.....iepGVPAKFRIQFIQ...--KESNKVILDKIVD...H...PR.TG.SS.YMGRYA.....................................-LLAQDTLQA.G.TYTIR.LDYLEGAPELAPLYAEIRFS-r.................
Q7N8S5_PHOLL/35-168                 ..........YKPIDVSKSGQSVKIDFEISKK..GNYQFALLFDKGDD.YEEMKK..............RLELF.......G.............................NVD.KD...........GVIIPVSLHLVK...----DSKIFFDKKIN...A...GG.RG.WG.QSLDYEgrri.............................nmavRNIKILELPP.G.RYSAV.ITILEDVPVFNDIESFVEFSY..................
D2U2U4_9GAMM/35-169                 ..........YRPIDITRAGQSVKVEFEIKKE..GGYLFALLFETGEG.HDEMER..............RFELF.......E.............................GIN.KT...........GVIIPISLRIVK...----DGQVFFDETIN...T...QG.TD.GG.QAFYYQgrri............................dttavRDIKSFLLFL.G.HYSVV.ISTLEDVPLFNGIESFVQVTY..................
D1B1Q1_SULD5/24-185                 .........s-IPIDLSQAGSVVEREVKIEET..WAYDLFLEFAVLDR.KEDGGLdg..........kkVRKFL.......GfnsynpydgkklgfgdyeqakrklgdlidETY.DC..........dGTIAPIKLTIHQ..iNKDNTKKLIVDNLYM...T...KG.YS.SG.---AYE.....................................RDIAIISLDK.G.KYIFR.IENIEAFQEMNARKVNFIIR-i.................
Q7N8S6_PHOLL/35-168                 ..........YRPIDVSKSGQSVKIDFELSKE..GNYQFALLFETGEG.YDEMER..............RFKLF.......G.............................RAD.KD...........GVIIPVSLYIVK...----DGKIFFDKKIN...A...SG.SE.GG.RVFNYEersi.............................ntavREIKTFLLPP.G.RYSAV.ITTLEDVPVFNDIESFVEFTY..................
G3IQH3_METTV/48-176                 ..........KMPIALHQAGSVTEADFNIAQD..DRITLRLRFFVNDQ.-GHRDR..............LLFFL.......D.............................SPE.KN...........KISVPLKIQITQ..hIGS-KNVSILERIYS...V...PG.LF.GI.AENFFD.....................................IKIDDLTIKS.G.KYRIR.LETIEEFPELSDTKVEFGVYY..................
A0A0Q8RIB2_9BURK/34-177             .......qmk-----LGEAGTVVTADVEVPVD..LKYDLMLELSNPAG.DSLSKQ..............DVSII.......Gdrrvedcge..........gvdlakvpkqERA.SF...........GRPMAFKVEVRH...--KPDNALVYSRTAN...T...LC.VA.SK.WANQRS.....................................RSLGNFALAR.G.AYSVR.VENVDAQAGLGHLNTTV----mla...............
Q7N8S7_PHOLL/35-168                 ..........YRPIEVSHSDQSVKIDFEISKK..GDYQFALLFATGRG.FGEMQR..............RDKLF.......G.............................SID.KD...........GVAIPVSLRVVK...----DGKVFFDEKIN...A...VG.SG.WG.RTFYYEerrv.............................nttvREIKTLSLPS.G.HYSAV.ITTLEDVPAFNDIQSFVQLIY..................
D1B2F0_SULD5/24-185                 .........s-IPIDLSQAGSVVEKEVKIEES..WSYHLILQFAVHDR.KEDGGLdg..........krVWKFL.......GfnsydprdgkqvgyvdyrlakselgdlidETY.DC..........dGTVVPIKITIHQ..iNQDNTKKLIADNLYM...T...KG.NG.SG.---AYT.....................................RDITTISLDK.G.KYIFR.IENIEAFSEMIGRKVDFTIY-i.................
W1JA23_9GAMM/1-89                   ..........----------------------..--------------.------..............---MF.......G.............................SIY.ED...........GIAIPVSLRLVK...----DGKVFFDKEIR...T...VG.SE.AI.RSFDYNeerk.............................nttvRDIKTLVLPP.G.RYSAV.ITILKNVPAFNGIESFVELTY..................
A0A497XLS7_9PROT/46-190             ........wd-----IAPKGSRIEVDFIVTEY..RVYEFDIGFGNKND.PDAKDQswr.......dddkNWQFI......sG.............................GRD.KLnngm...yphpSVVVPVHIKVEKl.lNVSAAPALVTEQTID...T...ES.RY.AG.GNLVM-.....................................RRIIHQKLRP.G.KYRVTaITT------------------resslpdslgtylrigfy
Q7N8T1_PHOLL/35-168                 ..........YKPIDVSKSGQSVKIDFEISKE..GNYQFVLLFETGEG.HDEMAR..............RFKLF.......G.............................RAD.KD...........GVIIPVSLYIVK...----DGKIFFDKKIN...A...SG.SE.GG.RVFNYEersi.............................ntavREIKTFSLPP.G.RYSAV.ITTLEDVPAFNGIESFVEFN-h.................
A0A0D7P371_9BRAD/35-177             vslrdpglil-------------SREFHAPVD..TSYLLNLRFVFPST.ESRIKD..............RLVGD.......Grtsdycds.............diqydaipDHE.RSg.........lGLPIPFRVVVRS...--EPEGASVVERTFH...S...LC.HA.AH.ARNDKH.....................................RTIGRLDINR.G.SYRIE.VTNLQPQIAFGDIKTEISL--vs................
A0A1G8JGX4_9RHOO/69-183             ....nkplrg----------------------..WTMYLAFLFKDGDL.-DDFRR..............VEEFA.......G.............................SLSgKN...........GISVRLHVSIVS...IGGHETSPIYDEVVL...V...EQ.KAsGA.GNGRID.....................................RIVDGVLLDP.G.FYRLE.VEAVDDIPVLIPESLKFGIAY..................
A0A2T5HA34_9PSED/34-197             .........q-RPFDVSLPDQVFRSSFIIKKE..YDYRFSLIFNWKNP.ENYQSQ..............EEQKLa.....tG.............................GFD.VK...........GLPLALNLTIVK...----DNEIFLDETIQ...T...QL.VS.RY.EGFCYNkkseknhprqtfmesifs.nidkcskkidsksiwgpsRTIDIRTLPP.G.NYRVE.IKTLSPAPAFSGMEAFISIS-p.................
I4MVY4_9PSED/25-152                 .........a-APLSLKTSGAVAGLSVRIAQG..DSYSVRIDYYYPPAdLAARKT..............LWEGA.......G.............................GVQ.DN...........GAPFNVNLRIYD...--VDDAVVIQDRRIS...H...PT.LS.SW.GDGVLH.....................................AELSEVHLPR.G.RYQIT.VERRGSAGAIAD---------yragvslv..........
G3IQH2_METTV/8-126                  .....nrnve----------------------..QNIGLRPLFLPNNQ.PGHLDR..............LLDFL.......G.............................RSK.KIgvl.....vplSISVPLKLRIIK...YTNFKESVILDKVYA...T...NG.IV.SS.GSTELN.....................................QLIDDLIIKS.E.KYRIR.LETIEAFPQLSDTKVEFGMYY..................
Q7N8S8_PHOLL/36-171                 .........r-KPIDVSHSGQSVEINFELSKRkaGNYQFALLFATGGD.YNEIDR..............RSKIF.......G.............................SVD.KD...........GIAIPVSLRLVK...----DGKVFFDKKVN...A...VR.LD.GW.QAFYYEkrli.............................nttvRDIKTLELLP.G.RYSAV.ITTLEDVPAFNDIESFVEFAY..................
A0A011R4N0_ACCRE/44-182             .........i-LPFFVQQAGNKVETELQVQEHrpYIIYLRLGFNENNP.-KDRER..............VRKVV.......G.............................DYG.RDadgk...llnpGVSVPLRLKIVI...IYASSNKTLLERDVL...E...EE.MW.AY.GADNFK.....................................KKIVTVSLKP.G.HYRIS.VETLKDMPELIGTAVELGIGY..................
W1INB7_9GAMM/1-131                  .........m------SHSGQSVEFNFELSKRkaGDYQFALLLDKGND.YEEMKR..............RLDLF.......G.............................DIN.KD...........GIVTPISLQIVK...----DGTIFFDEKIN...A...GG.LG.WG.QSFDYEgrri.............................nmavRNIKILELPP.G.RYSAV.ITTLENVPAFNGIESFVELTY..................
A0A0K1K0X0_9BURK/38-172             ........el--PSATAQSGQEVHFEIEIIKK..DQYLLGIKFLEKNT.PGDAAR..............LAQLL.......G.............................ASE.LDssgk...wieqGVPATIHVHIRK...--KNKNEEILNELVE...H...PK.TR.AT.YGGRAA.....................................-DISLINLEP.G.VYLVS.LKYMHLAPALNAIPENIF---fsk...............
A0A2L1GQ90_9DELT/33-159             .........q-MPIDLSQAGSVAESEFIVKVP..DVYRMQLNFETSRD.-KENNE..............VSKYL.......G.............................DLW.GDct......kgaGTIIPLHLTVSK...KTAGGTKAIMDEYIH...E...A-.--.-Y.EKASLS.....................................---RTMDLGP.G.RYRIR.LTNLLAHRHLQYVPVTVTLTY..................
D1B1Q4_SULD5/25-157                 ..........TMPIDLSKTGNVAETDIRIDKE..YRTGIALNYDFRRQ.KNKMTRne.........ynnIKVFF.......G.............................NSY.TS...........GTAIPVKLKIEK...IMDKNETTILNDII-...I...VD.NN.GG.HELHSS.....................................-LIKEIALSQ.G.KYRIK.VETTEDFSELSDLSVLVEIYY..................
A0A426VH48_9BURK/41-182             .........q-LPVDMSHAQTVVEAEFEIREE..TFYAFNLLYPFKEG.-DAAGRaqa.......vrlaG---ApflnpatG.............................RWE.EP...........GAGIDVHLSVIAl.aADGGQDRTVHDSEIE...R...PR.KT.SA.TADKLV.....................................SRLASVKLAP.G.RFKVR.LVNRHDAPQYRDAGTQFS---vvr...............
#=GC seq_cons                       ...........hPlslspuGpslch-hclppc..ssYphsLhFthsss..schpR..............hhchh.......G.............................sht.cs...........GlslPlpLpls+.......csplhhDcplp...s...ts.hs.us.tshphp.....................................RpIpphsLts.G.+Yphp.lpslcshPthsslps.lph....................
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