#=GF ID   DUF5646
#=GF AC   PF18881.4
#=GF DE   Family of unknown function (DUF5646)
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   SCOP:1wmi
#=GF GA   27.00 27.00;
#=GF TC   30.40 30.90;
#=GF NC   25.90 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   15768033
#=GF RT   Crystal structure of archaeal toxin-antitoxin RelE-RelB complex
#=GF RT   with implications for toxin activity and antitoxin effects.
#=GF RA   Takagi H, Kakuta Y, Okada T, Yao M, Tanaka I, Kimura M;
#=GF RL   Nat Struct Mol Biol. 2005;12:327-331.
#=GF DR   INTERPRO; IPR043706;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of unknown function. Family members include the
#=GF CC   archaeal homolog the bacterial RelB, a toxin-antitoxin system
#=GF CC   which is activated during amino acid starvation. This family is
#=GF CC   mostly found in thermococcus archaea [1].
#=GF SQ   2
#=GS F2KQ89_ARCVS/4-35  AC F2KQ89.1
#=GS Q5JGK7_THEKO/4-72  AC Q5JGK7.1
F2KQ89_ARCVS/4-35             vnae----NVEYVMKELERLKVEIQRLEAM-------------------------------------------sfqsre
Q5JGK7_THEKO/4-72             ....TTDARIEYILSELERLKVHIQRLESMLVPLVKDEVPEEELREIEMEARKFKEESEEWIDAEDLDEILED......
#=GC seq_cons                 ........plEYlhpELERLKVcIQRLEuM.................................................
//