#=GF ID   DUF5728
#=GF AC   PF18999.4
#=GF DE   Family of unknown function (DUF5728)
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Jackhmmer:W6UV12
#=GF GA   25.00 25.00;
#=GF TC   25.10 77.40;
#=GF NC   24.60 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR043786;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a highly conserved domain of unknown function found in
#=GF CC   Platyhelminthes, with many of the sequences annotated as being
#=GF CC   the small conductance calcium-activated potassium channel
#=GF CC   protein. However, the location suggests that this domain belongs
#=GF CC   to the intracellular amino terminus of these transmembrane
#=GF CC   proteins, immediately next to the calcium-activated SK potassium
#=GF CC   channel.
#=GF SQ   9
#=GS A0A158QW10_MESCO/481-665  AC A0A158QW10.1
#=GS W6UM49_ECHGR/125-316      AC W6UM49.1
#=GS A0A183SSK4_SCHSO/641-803  AC A0A183SSK4.1
#=GS A0A158RDG9_HYDTA/469-660  AC A0A158RDG9.1
#=GS A0A158QC81_HYMDI/463-650  AC A0A158QC81.1
#=GS A0A654GPV4_9CEST/709-860  AC A0A654GPV4.1
#=GS A0A0R3T5K3_RODNA/470-657  AC A0A0R3T5K3.1
#=GS A0A3P7LGH9_DIBLA/646-798  AC A0A3P7LGH9.1
#=GS A0A0R3W1A7_TAEAS/476-667  AC A0A0R3W1A7.3
A0A158QW10_MESCO/481-665             .......................v-DSDDCVPVCSTPKDSVEQEVAEEDEEGTITNSsDVTRPKRPYYCQKAQKFRNSWRTQSLESPKTGAGRGIVRERSLTMVESQSESDSKDT-NATAEDRTAQVTVYLTRGARNPVKTILVNHTANNMsAINAARLRARRQKTFSNRNQWKSVQLSPTHDGDIEKhywRGETFICNAHL---------------ytdltvnr..........
W6UM49_ECHGR/125-316                 ........................GDTEEFINLNSSSINSVEQETGEDQEDDTLIAStDMARPKRPYYCQKAQKFRNSWRTQSVENPQSTIEGKLVRDRSLTMVESQSGSDTKST-NGGNTDRGAQVTVYLTRGSRNPVKTILVNHNAANIaAANAARLRARRQKTFSNCNQWRSVQLSPTHDVETDKqgwLGDDELYNTSLCNIHESYPNN-----lclhr.............
A0A183SSK4_SCHSO/641-803             iiptdcapddilekkpnpeadfav---------------------------------.KLERLRRPHYFQKAQMFRQSWRTQSVEQ-STLADVVTIKRRSLTRVDSDSEQENEVP---------RFVNVVVERGAPNPVKTILINNSTDAHnSNNTE--RIRRQRTFANKRHWKSVQLPSVNISEPDD...EAAE----------------------lvshkesitpvqqvdtr.
A0A158RDG9_HYDTA/469-660             ........................GDADEFINLNISSKNSVEQETIEDQEDDTLMPSvDMTRPKRPYYCQKAQKFRNSWRTQSIANPQSTVEHGLVQDRSLTMVEPQPVSDVKNN-SGIITDRGAQVTVYLTRGSRNPVKTILVNHTASNMtAANAARLRARRQKTFSNRNQWRSVQLSPTHDVETEKqgwKGDDKLHNTSLCSIRESYLNNRIRVR..................
A0A158QC81_HYMDI/463-650             ........................GECEEYMNMFASGKNSTEQENTEDQEEDTLNNT.DMTRPKRPYYCQKAQKFRTSWRTQSVETPSNVIDHGLAQDRSLTMVESQSDSESKSTGHGTGQERNAQVKVYLTRGSRNPVKTILVNHNANIV.AANTDRLRARRQRTFLNRNQWRSVQLSPSHDPEMDR...RAGERSYNASLCDSRESYVGHRFNRK..................
A0A654GPV4_9CEST/709-860             daapddvldkkssltqevdfavkp---------------------------------.--ERIRRPHYFQKAQMFRQSWRTQSTEQG-PLTDVVAVKRRSLTRVDSDSEHEDEVP------HEPRFVSVVVGRAAPNPVKTILVNNSGSAH.VNDNDTERMRRQRTFARKRQWKSLHLPS--------...--------------------------vnisepddappnmssc..
A0A0R3T5K3_RODNA/470-657             ........................GEYEDGMNMLASERSCTEQEATEDQDEDTLTNS.DMTRPKRPYYCQKAQQFRTSWRTQSVDTPSSIMNYGLSQDRALTMVESQSDSESMSPGNGIGQDRNAQVKVYLTRGSRNPVKTILVNHNANPM.AANADRLRARRQRTFSNRNQWRSVQLSPSHDTEIDR...RGDERSYNASLRESRESYVGNRGNIK..................
A0A3P7LGH9_DIBLA/646-798             ......kknnppppqeadcavrpd---------------------------------.---RFRRPHYFQKAQMFRQSWRTQSIEQG-PLTDVVTMKRRSLTRVDSDSEQE--NE----VSRQPSFVNVVVGRAAPNPIKTILINSNSTV-.YSNNNAARIRRQRTFANKRAWKSVNISEPENETTD-...--------------------------mglskesitlaqqtdnrv
A0A0R3W1A7_TAEAS/476-667             ........................GDAEEIINLNVSSKNSMEQETVEDQEDDTLMPStDLTRPKRPYYCQKAQKFRNSWRTQSIGNPQSTIEHGLVRDKSLTMVESQSVGDTKST-VGINTDRGTQVTVYLTRGSRNPVKTILVNHNASSTaAASAARLRARRQKTFSNRNQWRSVQLSPTHDVEAEKqgwRGDEKLHNTSLRNIQESYVNNRCM--hk................
#=GC seq_cons                        .........................-.--hhsh..o.hsshEQEshE-p--sTl.so.DhsRPKRPYYCQKAQpFRsSWRTQSlEsPpohh-hsll+-RSLTMVESQS-u-scss..uhsp-RsuQVsVYLTRGuRNPVKTILVNHsAssh.AuNssRLRARRQ+TFuN+NQW+SVQLSPoHDsEh-+...cus-..hNspL...............h.................
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