#=GF ID   DUF5729
#=GF AC   PF19000.4
#=GF DE   Family of unknown function (DUF5729)
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Jackhmmer:W6UV12
#=GF GA   27.40 27.40;
#=GF TC   28.30 78.60;
#=GF NC   26.90 18.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR043787;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a highly conserved domain of unknown function found in
#=GF CC   Platyhelminthes, with many of the sequences annotated as being
#=GF CC   the small conductance calcium-activated potassium channel
#=GF CC   protein. However, the location suggests that this domain belongs
#=GF CC   to the intracellular amino terminus of these transmembrane
#=GF CC   proteins, near the calcium-activated SK potassium channel.
#=GF SQ   9
#=GS A0A0R3W1A7_TAEAS/333-473  AC A0A0R3W1A7.3
#=GS A0A158QW10_MESCO/338-478  AC A0A158QW10.1
#=GS A0A3P7LGH9_DIBLA/479-631  AC A0A3P7LGH9.1
#=GS A0A0R3T5K3_RODNA/328-468  AC A0A0R3T5K3.1
#=GS A0A183SSK4_SCHSO/440-532  AC A0A183SSK4.1
#=GS A0A158RDG9_HYDTA/326-466  AC A0A158RDG9.1
#=GS A0A654GPV4_9CEST/504-648  AC A0A654GPV4.1
#=GS W6UM49_ECHGR/1-122        AC W6UM49.1
#=GS A0A158QC81_HYMDI/321-461  AC A0A158QC81.1
A0A0R3W1A7_TAEAS/333-473             GFSQLRSVKGIKHDREKQEMCSALPPAIIANLDNRGAVALLAASTRPRLIANMRKKTNKAHSSQEEVP.TSLKPIAWASSFDSSCN..LQSQDDDYSRSGPLKWEESSCVQLTSKQSSLINRSSNCRGSITQEALLGVKNSKLS................................................................................
A0A158QW10_MESCO/338-478             GFSQLRSVKGMKLDREKQEMCSVLSPSVAAKLDNRGAVAVLAASTRPRLISRMHKKPNKAHSSQE-AP.TTLHPAPWASSFDSSCNmqHQSQDDELTRCASIRTDDTPPPPQTTKQSSLINRPT-QKNTPNPETLGGVKNCKPS................................................................................
A0A3P7LGH9_DIBLA/479-631             GFSQLRSVKDIKHEREKQEMCSALSAAIASSLDTGGAVAALAANTRPRFKANWIKKRLQV-SSQEEPSlETRASNPY---------..--------------------------------------------------------aqeremmehsacgssfptsssskqnhsegflsgsestqkaapgkgehqisvpsgensvaeqgsfatmqnslsrgsin...
A0A0R3T5K3_RODNA/328-468             GFSQLRSVKGIKHDREKQELSSALSPALAAGLDTHGAVALLAASTRPRLIASMRKKTAKAHSSQEEVP.TTQRSTTWTNSFDSGSN..VQSATEEYSRCGPLKAEEIPSVPPTSKQSSLANRPTTHRGSITLETGSGTKGYKLS................................................................................
A0A183SSK4_SCHSO/440-532             GFSQLRSVKDIKHEREKQEMCSALSAAIASSLDTGGAVAALAANTRPRFKATWIKKRLQV-SSQEEPS.-----------------..--------------------------------------------------------lesrasnpyvqdaeilersscgssfp......................................................
A0A158RDG9_HYDTA/326-466             GFSQLRSVKGIKHDREKQEMCSALSPSIIANLDTRGAVALLAASTRPRLIANMRKKANKAHSSQEEVP.NSLKPTIWASSFDSSCN..IQSQDDDYSRNGPLKREESSYVHLTSKQSSFINRSSNHRGSIAQEALLGIKNCRLS................................................................................
A0A654GPV4_9CEST/504-648             GFSQLRSVKDIKQEREKQEMCSALSAAIASSLDTGGAVAALAANTRPRFKANWIKKRLQV-SSQDD--.-----------------..--------------------------------------------------------psleirtsnlyahdgetldrsphgssfphaskqnhsdsfpshcessqkpahvrgimnprltddtslirdstcarkaiesg
W6UM49_ECHGR/1-122                   -------------------MCSAFPPAIVANLDTRGAVALLAASTRPRLIANMRKKTNKAHSSQEEVP.TSLKPITWASSFDSSCN..IHSQDDDYSRSGPPKWEESACVPMTGKQPALINRNSNYGGSIAQETLLGIKNCKLS................................................................................
A0A158QC81_HYMDI/321-461             GFSQLRSVKGIKHDREKQGLSSTLSPAIAASLDTHGAVALLAASTRPRLIASMRKKSAKAHSSQEEVP.VTQRATTWASSFDSGSN..AQFTDEEYPRGGPLKTEEIPPVPPTSIQSSLANKPTIRRGSITPEAVSGVKGYKLS................................................................................
#=GC seq_cons                        GFSQLRSVKsIKH-REKQEMCSALSPAIAAsLDT+GAVAlLAASTRPRLIAsM+KKssKAHSSQEEsP.so.+shsWssSFDSusN..hp.ts--hsRsus.+h--.s.s..TshQsuhhN+so..tso.s.Esh.GhKs.+.S................................................................................
//