#=GF ID   DUF5870
#=GF AC   PF19195.4
#=GF DE   Family of unknown function (DUF5870)
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Moenttinen H;0000-0003-2461-0690
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   26.90 78.30;
#=GF NC   22.70 22.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR043806;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of uncharacterised proteins of unknown function
#=GF CC   predominantly found in viruses.
#=GF SQ   10
#=GS A0A2U7U9Y1_9VIRU/72-573   AC A0A2U7U9Y1.1
#=GS A0A2U7UGK7_9VIRU/218-770  AC A0A2U7UGK7.1
#=GS A0A2U7U7M8_9VIRU/203-713  AC A0A2U7U7M8.1
#=GS S4VZ81_9VIRU/188-707      AC S4VZ81.2
#=GS S4VW88_9VIRU/66-565       AC S4VW88.2
#=GS S4VR65_9VIRU/67-565       AC S4VR65.1
#=GS S4W551_9VIRU/209-736      AC S4W551.1
#=GS A0A0B5J946_9VIRU/74-533   AC A0A0B5J946.1
#=GS A0A2U7UCZ1_9VIRU/56-537   AC A0A2U7UCZ1.1
#=GS A0A2U7UFR9_9VIRU/56-542   AC A0A2U7UFR9.1
A0A2U7U9Y1_9VIRU/72-573              ..........l-TDCTDQATAVRLFCTRWSRLRAQLDPLTAATRGIRLEQAALRRDLAAYMEGARIRRAVV...kC...GG.D.DN.ATIVVRVDPMRPTTSMKREVITAAVYEHVTPDLVRACA.EAAAAAAEKRSAKVAKAKAVAARKAARAAAAAARP.AKRRRRTak........heDDDKDNETKDDAT...PT.KTS--MVD.......INPV....A........TDENMVNA..STTND-----DDA...DGA.GDAHl..gNTPALAEIIGAAVVEATRAAQRRATAQQT.SLTVGRY...D.............P.D..RDDESAM-VDMWDASps...................stkTC.DLLCPDAQSaqvNGKPEEPACTLAT.NAWSTEDVPVEVRAWAARFVELADVASGLRDRMRPIEVAIEALTLDLP....PPPPEpap...........................rrtPAKGTARNRPSA.RAIEAAAKRERHEAFGPMRDAVARHLA..E.V..G..ADKR.G.VPVRF.........PTSD.....A.......LYRLRESVRTRTGTLTRTDYAPLAADAAAAAMAQVEIDPAVPYSPEAAADLLEDDEFRNRLFDAVTGGIDQHRERGT.IRTRAVSLVRVaASRDPVAPAP......................
A0A2U7UGK7_9VIRU/218-770             ...sdddddkg------HDALVR-LCRKWRTSRVRLETLAAASKVLRQERNELERRLINHMRERGIDDVDA....F...GTiE.RG.RRVKVHIKQAPTTCSVSDKILRAAVFQHVSAEMAHMCAiDEAAKKAAREARKAKEASSSSSKKRGPYGDAPGLPqAKHPRRT............STGPSSPTASDRAsyrPD.GGLVEKSEridrassTDAS....S........D-SHDDDAsgSNYDDDDDSYDDSgsdDDG.GQVV....QGVSLSEALGAALAQARRQAQREIATPRF.IVEVFVY...D.............HkDraREHEPLM-IDMSKGK........................A-.RAQGQDAVK...KGRRRR--ARLDTrDPSSPPKLSREATQWAARLHVVIENLAKIRAEASPLRAHMAALTVDLP....SPTSSpsqlqsashpatttdganadggdtaiadtaaaaRGGTSSKSTPTA.RAAAAEAKRLRHARYASLRDSVAAYLN..A.H..GprPDERgG.LAVRFvesaggrntPGTT.....A.......TYRIRTVERGRNGNITVGRYAAAATSAASTALSAVGLRPDRPASKAALDRAFGNAAVRAVLFDALKTSLADTREKCKaTLTRNLVITKVpSGPSPSK---rap...................
A0A2U7U7M8_9VIRU/203-713             ...ddeddgyg---------TLVALCRRWRSARIQADALSATAKTLRHERKDLEKRLITHMSRRNIAKEDAfgslP...GG.Y.RA.KVTIVRA---PTSCSVSDKVLSMAVYKRLSIELAHECA.LAEANKAAKTATR--------AKKRAPASALLAPQ.AKHPRRTsse.....tgspQAASDRATRPDNV...V-.GDDGHAKR.......DEEH....A........DHSFSSDT..ASQDDSNDSEDNS...QDD.EDDDngivDGISLAEAIGAALAKARRDAQETLCQPRL.MVKVVVY...ParqgvhkheplivP.V..MTDKDGNEVDDKEAW........................NRwTTMT--AKE...KRAMAAASKAAAA.EAAARVELSPEAAQWAGRIYEIDQALERNRAEAGPLRALMAALTVDLP....DAPSTtttq........................sattpNGNGDDDAKPINgRTKAAEAKRLRHAQHAAMRDRVAAYLAanH.Q..H..ADERgG.LAVRFi.......sPCSA.....TgsagapvTYRIRAVERARNGNMGVRRYATAAVSAAAASLAAVGLDPTRPYSPARLQQAFGDRGVRSHLLDALKRAIATERQ---.-----------.----------ackpplarnlv...........
S4VZ81_9VIRU/188-707                 ....daaqtda-----KRARSLAILCAEWKDHRIKWQALQAKARALRKERNEVAGKLAAQMERDKVTCACA....P...IG.G.GR.RVKACLIQPQRS-YSISEKTITAAVYTHASMKLAAACT.AATPDPSVGPSVPSSLPLSLASRKRPLADAAPSPA.AKHHRPMtta.....spldGNRHEHDRVREAV...PYaKGADDNYD.......DDNY....DddddddddDDDDDDDI..SDDKDEEKEQHEE...DRSdDDTD....ASMGLGQVLAKVVLSATAKEQEAITKKRApTVTVVAY...D.............E.R..HKDL-------NEG-........................--.-FLVADTES...QR-----------.QAMALPVLPPDLAEWAERVHVLNGALARLSRRIAPLTASMAALTADLPtdepPTTTTtasavataderde.......knsarqkkkpkrkTAKQIARAEEQA.RATE--ERRLRHAQHAELRDDAAAYLR..VhVpkG..DAAS.G.LPILF.........PPATpngppV.......TYRIRVVRRVPKGSVGKDGYAAAAVEAAAATLAAVGIDPERPYSPRVLAGLLGTTTTRDLLFANLKASLARRRVI--.-----------.----------pnapavralaitkmptkkkkhp
S4VW88_9VIRU/66-565                  ...........PLDCTDQATAVRLFCARWSRMRAQLDPLTAATRGIRLEQAALRRDLAAYMEGARVRRAVV...kC...SR.DnDN.TAIVVRVDPTRPTTSMKREVITTAVYEHVTPDLVRACA.EAAAAAAEKRSAKVAKAKAVAARKAARAAAAAARP.AKRRRRT............AKRHANDSDDSGD...GG.NGGGGHVD.......KDGA....A........SQE--VSA..SSADI-AVTDGAC...IAS.DDGDv..gGALALADIIGAAVVEATKVAQRRATAQQT.TLTVGLY...D.............P.D..RDDESAM-VDAWDASps...................sagTC.EPLPCDAEA..aQDKPEGSASTLAT.YAWSTEDVPAEVRAWATRFVELADVASGLRDRMRPIEIAIEALTLDLP....PPPETtp............................akaPARGGARNGPSA.RAIEAAAKRERHDAFAPMRDAVARHLS..E.V..G..ADRR.G.VPVRF.........PTSD.....A.......LYRLRETVRTRTGALTRTDYAPLAAGAAAAAMSQIEVDPAAAYSPDAAADLLEDDEFRNRLFDAVAGGIDQHRERGT.VRTRAVSLVRVaASRDPVAPTP......................
S4VR65_9VIRU/67-565                  ...........PTDCTDQATAVRLFCARWGRLRAQLDPLTAATRGIRIEQTALKRDLAAYMESARVRRAIV...dC...GG.K.GDgAVIVVRVDPTRPTTSMKRPVITTAIYEHVTPDLVRACA.AAAAAAAEKRSTKAAKAKATAARKAARAAAAAARP.AKRRRRT............AKQD--DEQEDGA...PA.ETPAPAVV.......ASVV....A........TDEDPV--..-------------...-GA.DG-C....NAPTLADILGAAVVEATRVAQRYATAQQT.TLTVGLY...D.............P.D..RDDESAM-ADAWDAAppastpreapcpgtpshpggddnnTK.DDCGGDGNK...DDKTDKHVNATAA.YAWLTTDVPPEVRAWATRFVELADVMSGLRDRMRPLEVAIEALTLDLP....PPAPEph.............................rtPAKATARGKPSA.RAIEAAAKRERHEAFGPMRDAVAQYLA..A.A..G..ADKR.G.VPVRF.........PASP.....A.......LYRLRASVRTRTGTLARTDYVPLAANAAAAAMAQVEIDPAMPYSPEAAADLLEDDEFRNRLFDAVADGIDQHRERGT.VRTRAVSLVRAsAGRDPTAPP-p.....................
S4W551_9VIRU/209-736                 dddsddddgyg---------TLIALCSGWRSARIKVDALSAAAKTLRHERKDLAKRLIDHMSRRKIADEDA...fG...SL.P.GD.WRVKVTIVRAPTSCSVSDQVLSAAVYKRLSVQMAHDCA.IAEADKAAKKCS------SNGAKKRAPASALPAPQ.AKHPRRTspssalpepgspPAASDRAVRLDNN...SG.GGDDDNDD.......ARQSdegrT........DHSSSSDA..ASQDSSNSEEEDE...NND.N--EvgivHGISLAKAIGAALAKARREAQETLTQPRF.TVNVVAYpavEaarkh...epfiiP.V..ATDENGNQVDDEFEA........................WQ.RWMAMAKEE...KRAITDAAKAAAA.EAAARVELTPEAAQWAGRIYEIDQALERNRAEAGPLRALMAALTVDLP....NAPSTtttttq.....................sattpnGNGDDDDAKPINgRTKAAEAKRLRHAQHAAMRDRVAAYLA..A.NypH..ADER.GgLAVRFv.......sPRSA.....TggasapvTYRIRAVDRARNGNMGVRRYATAAVSAAAASLAAVGLDPTRPYSPARLQQAFGDRGVRSHLLDALKRAIAAERQ---.-----------.----------ackpplarnlv...........
A0A0B5J946_9VIRU/74-533              ..........l-ADCTDQATAVRLFCTRWSRLRAQLDPLTAATRGIRLEQAALRRDLAAYMEGARTRRAVI...qCrggDG.D.DN.ATIVVRVDPMRPTTSMKREVITAAVYEHVTPDLVRACA.EAAAAAAEKRSAKVAKAKAVAARKAARAAAAAARP.AKRRRRTakhd...ddddgDDDKNNEAKNDAG...SA.NTP--MVD.......NNPV....A........TDDNTVNA..GDVGA----IDDA...DGT.GDAHl..gNTPALAEIMGAAVVEATRAAQRRATAQQT.SLTVGRY...D.............P.D..RDDESAM-VDMWDASpss..................tkgAC.EVSCPDARDvqvDGKSQEPVCALAA.YAWSTEDVPVEVRAWATRFVELADVASGLRDRMRPIEVAIEALTLDLP....PPPSEpap...........................rrtPAKGTARNRPSA.RAIEAAAKRERHEAFGPMRDAVARHLA..E.V..G..ADKR.G.VPVRF.........PTSD.....A.......LYRLRESVRTRAGTLTRTDYVPLAADAAAAAMAQVEIDPAVPIR---------------------------------.-----------.----------prp...................
A0A2U7UCZ1_9VIRU/56-537              ...........PIDTGDRDQAVRLFCARWSRLRAQLDPLTSAMRGIRTEQTVLKRDLAAYMERTGVRRAIV....R...DR.S.GD.PTVVVRVDPKRPTTSMAPEVLTTAVYEHVTAHLVEACA.EAAALRAKKQADKVAKANALAARKAARAAAAAARP.AKRRRKR............SDKS---DADDAE...PL.GGATENQT.......PAAS....A........DEPETTVA..SSACDKEAEQKAC...--A.DQGD....DGPPLAEILGEAVVEATRVAQRRATADQV.TLTVGIY...D.............P.D..RDDESSMHV-DEEAH........................LC.DALVDQTTS...GDISQTPSVGRSY.RAWAAVDVPDEVRSWATRCVELDQVAAGLRDRMRPLETALESLTLDLA....PTPEK.................................AAGNSKRVQPSA.RALDAAEKRQRHAAFAPARDAVAHYLN..E.A..G..AGKR.G.VPVRF.........PDSD.....A.......LYRLRESVRTRAGTVTRTDYRPLAAGAAAAAMAQVEVDPATPYSAEAALDLLDDAEFRNRLFEAVTGGVAHHREQGT.VRTRAVSLVRV.GGRAPREPAS......................
A0A2U7UFR9_9VIRU/56-542              ...........PIDIDDRDQAVRLFCARWSRLRAQLDPLTSAVRGIRAEQTAIRRDLTAYMERTGARRAIV....Y...DR.N.GA.PIVAVRVDPKRPTTSMAAEVLTAAVYEHVTTQLVEACA.EAAAQRAKKQADKVAKANAVAARKAARAAAAAARP.AKRRRRG............GAKSNLGEEKDGA...PS.LTDTQKDQ.......CDVP....A........DDQKATDA..PDVDGKQAKEDIA..hVQT.HQCE....DGPPLAEILGEAIVEATRVAQRHATKDKV.TLTVGRY...D.............P.G..RDDESSMHIDDEEAS........................MC.ESMVSQTTP...AGLPATLSTHRSY.SAWAAVDVPDEVCARATRYVELDEVASGLRDRMRPLETALESLTLDLP....PTTTE.................................--KASKRAQPSA.RALDAAEKRQRHEAFAPARDAVAHYLS..E.V..R..AGKR.G.VPVRF.........PDSD.....A.......LYRLRESVRTRAGTVTRTDYRPLAAGAVAAAMAQIEVDPATPYSADAALDLLDDVEFRNRLFEAVTGSVAQHREHGT.VRTRAVSLVRV.GGRAPHEPTP......................
#=GC seq_cons                        ..........h.hDhsDpspAVRLFCuRWuRhRAQLDPLTAAsRGIRtEQssL+RDLAAYMEcs+lRRAll....s...us.s.ss.ssllVRVDPtRPTTSMuccVlTAAVYEHVTs-LV+ACA.-AAAstAcKcusKsAKApAlAARKAARAAAAAARP.AKRRRRT............uscsspssccDus...Ps.sssspps-.......scss....A........D-spsssA..usscsppspp-ss...ssu.css-....susuLAEIlGAAVVEATRsAQRcATspps.TLTVGhY...D.............P.D..RDDESuM.VDsp-Au........................sp.-shssDups...pctsppsusshAs.pAWussDVPsEVpuWAsRhVELs-VhuGLRDRMRPLEsAlEALTLDLP....PsPopss............................tpssA+uouRucPSA.RAl-AAAKRpRHsAFAPMRDAVApYLu..c.s..G..AD+R.G.VPVRF.........PsSs.....A.......LYRLRpoVRTRsGolTRTDYAPLAAuAAAAAMAQVElDPApPYSPcAhtcLLsDsphRs+LFDAlpsulAp+REpsp.hhTRslsls+s.uu.sP.t.........................
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