#=GF ID DUF6003
#=GF AC PF19466.3
#=GF DE Family of unknown function (DUF6003)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 35.40 35.40;
#=GF TC 37.00 36.90;
#=GF NC 30.80 29.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 12940979
#=GF RT Analysis of the biosynthetic gene cluster for the polyether
#=GF RT antibiotic monensin in Streptomyces cinnamonensis and evidence
#=GF RT for the role of monB and monC genes in oxidative cyclization.
#=GF RA Oliynyk M, Stark CB, Bhatt A, Jones MA, Hughes-Thomas ZA,
#=GF RA Wilkinson C, Oliynyk Z, Demydchuk Y, Staunton J, Leadlay PF;
#=GF RL Mol Microbiol. 2003;49:1179-1190.
#=GF DR INTERPRO; IPR046045;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0000100) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, polyketide. This family
#=GF CC includes a protein from monensin biosynthetic gene cluster from
#=GF CC Streptomyces cinnamonensis [1].
#=GF SQ 70
#=GS G2GKI9_9ACTN/1-140 AC G2GKI9.1
#=GS A0A0L8LGB1_9ACTN/1-140 AC A0A0L8LGB1.1
#=GS D9XKY4_9ACTN/1-140 AC D9XKY4.1
#=GS S4M9T2_9ACTN/1-140 AC S4M9T2.1
#=GS A0A7W7PRX5_9ACTN/1-140 AC A0A7W7PRX5.1
#=GS A0A101ND21_9ACTN/1-140 AC A0A101ND21.1
#=GS A0A1Q5MSX6_9ACTN/1-140 AC A0A1Q5MSX6.1
#=GS Q82RS8_STRAW/1-140 AC Q82RS8.1
#=GS A0A1V9KJK9_9ACTN/1-140 AC A0A1V9KJK9.1
#=GS A0A1Q5LLR0_9ACTN/1-140 AC A0A1Q5LLR0.1
#=GS A0A0X3XHU7_9ACTN/1-142 AC A0A0X3XHU7.1
#=GS A0A0X3WAZ9_9ACTN/1-140 AC A0A0X3WAZ9.1
#=GS A0A7M2T9N8_STRCW/1-140 AC A0A7M2T9N8.1
#=GS A0A1Q5KCG3_9ACTN/1-140 AC A0A1Q5KCG3.1
#=GS A0A7K3GKB6_9ACTN/1-140 AC A0A7K3GKB6.1
#=GS M3C040_9ACTN/1-140 AC M3C040.1
#=GS A0ACQ1_STRA7/10-149 AC A0ACQ1.1
#=GS A0A5J6HPA0_STRAD/1-140 AC A0A5J6HPA0.1
#=GS A0A0J7AL03_9ACTN/1-140 AC A0A0J7AL03.1
#=GS A0A2G9DK31_9ACTN/1-140 AC A0A2G9DK31.1
#=GS A0A3N6I8A2_9ACTN/1-140 AC A0A3N6I8A2.1
#=GS A0A100Y6T5_9ACTN/1-140 AC A0A100Y6T5.1
#=GS A0A3R8TBF5_9ACTN/1-140 AC A0A3R8TBF5.1
#=GS C9YVR7_STRSW/7-146 AC C9YVR7.1
#=GS A0A1A5NUG5_9ACTN/1-140 AC A0A1A5NUG5.1
#=GS A0A1J4Q8Q5_9ACTN/1-140 AC A0A1J4Q8Q5.1
#=GS A0A5Q4SX13_9ACTN/1-140 AC A0A5Q4SX13.1
#=GS A0A0L8L572_9ACTN/1-56 AC A0A0L8L572.1
#=GS A0A0F5VJR7_9ACTN/1-140 AC A0A0F5VJR7.1
#=GS A0A2S9Q2U8_9ACTN/1-142 AC A0A2S9Q2U8.1
#=GS A0A089X3P7_STRGA/1-140 AC A0A089X3P7.1
#=GS A0A0M8QL01_9ACTN/1-140 AC A0A0M8QL01.1
#=GS A0A510TH50_9ACTN/1-140 AC A0A510TH50.1
#=GS A0A1D8FVQ9_9ACTN/1-141 AC A0A1D8FVQ9.1
#=GS A0A7K2XF81_9ACTN/1-140 AC A0A7K2XF81.1
#=GS A0A0Q9AR65_9ACTN/1-140 AC A0A0Q9AR65.1
#=GS A0A2P8QFY2_9ACTN/1-140 AC A0A2P8QFY2.1
#=GS A0A2U9PBC3_STRAS/1-140 AC A0A2U9PBC3.1
#=GS A0A7K2JIY9_9ACTN/1-140 AC A0A7K2JIY9.1
#=GS A0A0N0ANE4_9ACTN/1-142 AC A0A0N0ANE4.1
#=GS A0A7W7U861_9ACTN/1-97 AC A0A7W7U861.1
#=GS A0A117QLW7_9ACTN/1-140 AC A0A117QLW7.1
#=GS A0A4P6U401_STRSO/1-140 AC A0A4P6U401.1
#=GS A0A6H0CEI2_9ACTN/1-140 AC A0A6H0CEI2.1
#=GS A0A0U3N4J8_9ACTN/1-140 AC A0A0U3N4J8.1
#=GS A0A7J0CF33_9ACTN/1-140 AC A0A7J0CF33.1
#=GS A0A1Q5LPD3_9ACTN/1-140 AC A0A1Q5LPD3.1
#=GS A0A7W9Q1C4_9ACTN/1-140 AC A0A7W9Q1C4.1
#=GS A0A176L0R6_9ACTN/1-140 AC A0A176L0R6.1
#=GS A0A117RG42_9ACTN/1-140 AC A0A117RG42.1
#=GS F3NGP7_9ACTN/1-140 AC F3NGP7.1
#=GS A0A4S2SQV0_9ACTN/1-140 AC A0A4S2SQV0.1
#=GS V4J281_9ACTN/1-140 AC V4J281.1
#=GS A0A1Q4ZPK8_9ACTN/1-140 AC A0A1Q4ZPK8.1
#=GS V6L0D2_9ACTN/1-140 AC V6L0D2.1
#=GS A0A101SXN3_9ACTN/1-140 AC A0A101SXN3.1
#=GS A0A2U3A0A3_9ACTN/1-140 AC A0A2U3A0A3.1
#=GS A0A3G2J797_9ACTN/1-140 AC A0A3G2J797.1
#=GS A0A2W2M5E4_9ACTN/7-74 AC A0A2W2M5E4.1
#=GS A0A6G2VT57_9ACTN/1-140 AC A0A6G2VT57.1
#=GS B4UX69_9ACTN/1-140 AC B4UX69.1
#=GS A0A0N1GUD2_9ACTN/1-140 AC A0A0N1GUD2.1
#=GS A0A7L4XV37_9ACTN/1-140 AC A0A7L4XV37.1
#=GS A0A7K2QMW1_9ACTN/1-118 AC A0A7K2QMW1.1
#=GS A0A1V6MXR1_9ACTN/1-140 AC A0A1V6MXR1.1
#=GS A0A1D2I991_9ACTN/1-140 AC A0A1D2I991.1
#=GS A0A7K3DJ58_9ACTN/1-140 AC A0A7K3DJ58.1
#=GS A0A1Q5KGE5_9ACTN/1-140 AC A0A1Q5KGE5.1
#=GS A0A0M8XR50_9ACTN/1-140 AC A0A0M8XR50.1
#=GS D5ZVT0_STRV1/1-140 AC D5ZVT0.1
G2GKI9_9ACTN/1-140 ..........................MTDETYLFLVGDAAAP..TGVPLAAVGDLACMETPAVRAWLDAQNVAASSPRLRLLPPEENAAVPEGAERLPVPLSGEEVNRLRRGMAPEPLARIEEELLAYRDSSDGRDDLIGRALAAGVPPHRVVELTGVDPATVTAAA-g......
A0A0L8LGB1_9ACTN/1-140 ..........................MTDDAYLFLLEDPSAP..LGVTPAAVDDLACMETPAVRAWLDAQGSTPTSPHLRLLPPEETAAIPEGAERLPVPLSDEELSRVRHRLVPEPLAQVEEELLAYRDSAEGRDGLIGRALAAGVPPHRVVELTGVDPAEVTQAA-g......
D9XKY4_9ACTN/1-140 ..........................MAETAYLFVLPDPGTP..LGAPAVAVGDLECMETPAVLAWLHAHDVTADSDLLRVLPQEADGSIPEDAERLPIPLSADEADRVRGACAPRSTAEVEAELRAFRHTNADRDRLISQALTRGVPAHRIAQLTGLDPAEVAQIT-g......
S4M9T2_9ACTN/1-140 ..........................MTDDAYLFLLDDASAR..LGVAPAAVGELACMETPAVRAWLDAQGSTPASPHLRLLPPEETAAIPEGAERLPVPLSDEELSRVRHRMAPEPLARVEEELLAYRDCADGWDGLIGRALAAGVAPHRIVELTGVDPATVNAAA-n......
A0A7W7PRX5_9ACTN/1-140 ..........................MTDDAYLVLLNGPAGE..LGVPPAAIGELACMETPAVRAWLDAQGVTATSAELRLLPPEETAAIPEDAERLPVPLGDEELNLVRHYAAPRNVAQVEEELLAYRSCAAGRDALLTRALAAGVPAHRVAELTGEDLAHVKAVA-r......
A0A101ND21_9ACTN/1-140 ..........................MTDDAYLFLLDDASAR..LGVPPAAVGELACMETPAVRAWLGAQGTTATSPHLRLLPPEETAAVPEGAERLPVPLSDEELSRVRHHLAPESLAGVEEELLAYRDCADGRDGLIGRALAAGVPPHRVVELTGVDPATVTAAAQ.......
A0A1Q5MSX6_9ACTN/1-140 ..........................MTDDAYLALLDGTAAA..LGVPPAAVGELSCMDTPAVQAWLDAQGVTTASPRLRLLPPEEAGAIPDGAERLPVPLSDDELSLVRHRTSTETIAGVEEDLLAYRSCTDGRDALLTRALATGVPAHRVAELTGEDLTDVKAAS-r......
Q82RS8_STRAW/1-140 ..........................MTDDAYLFLLDDPAVP..LGVPPSVAGELSCMDTPAVRAWLDAQGVTTTSPALRILPPEQTAAIPEQAERLPVPLSEAELSRLRHHNAPEAVARLEEELLAYRDCTDGRDTLLRRALAAGIPLARIVELTGEEPAAVAAS--sg.....
A0A1V9KJK9_9ACTN/1-140 ..........................MTADAYLVLLNGTAST..LGVSPAAVGDLACMETPAVQGWLHAQGASVPSSRLRLLPPEETSGIPEEAERLPVPLSDEELSRVRHHATSQGVGRMEEELQAYGFQMGGRESLIIRAFAAGVPAHRIAELTGEDLAAVKEIA-l......
A0A1Q5LLR0_9ACTN/1-140 ..........................MADDAHLFLLPDRHPL..LGAALAAVGPLECAETPAVRGWLQAHAVSAASEQVRILPAGSEVLIPEDAEHLPVPLSEDEALRVQQECAPQSVTDVEAELLDFRETTQDWEALVHRALTAGIPAPRIAQLTGLPPQEIGRLT-q......
A0A0X3XHU7_9ACTN/1-142 ..........................MTEDAYLFLLDDADAAapLGVAPAAVGDLASMDTPAVRAWLDAQRVTAADPRLRLLPPEETGAIPEGAERLPVPLGDEELSRVRHTTAPEPLARVEEELLAWRDCADGRDGLIGRALAAGVAPHRIVELTGVDPATVTAAA-h......
A0A0X3WAZ9_9ACTN/1-140 ..........................MADDACLFLLPARHPL..IGAPLAAVGELECRETPAVQGWLHAHGVSASSEFVRILPAETEAIIPEEAERLPVPLSPEETIRVQQACAPRSVTDIESELLDFRDTTRERESLVHRALTAGIPAPRIAQLTGLDPQEVGRLT-q......
A0A7M2T9N8_STRCW/1-140 ..........................MTDDAYLFLLDDASAP..LGVAPAAVGDLACMETPAVRAWLDAQGTTPTSPHLRLLPPEETAAVPEGAERLPVPLSDEELSGVRHRMAPKPLARVEEELLAYRDCADGRDGLIGRALAAGVPPHRIVELTGVDPATVSAAA-g......
A0A1Q5KCG3_9ACTN/1-140 ..........................MADDALLFVLPERHPL..LGAALSAVGGLECAESPAVLGWLHAHGLPASSERVRIVPAGAAVLVPEEAERLPVPLGEEETLRVEHACAPRSVTDMESELLSFRDTTQDWQSLVHRALTAGIPAPRIAQLTGLDPLDIVQA--vg.....
A0A7K3GKB6_9ACTN/1-140 ..........................MADDAYLFLLPERHPR..LAAPLAAVGPLECLETPAVRGWLSAHDTAPGSEQVRILPAAKDVLIPEDAERLPVPLTADEALRVEQECTPASITDLERELLGFREVTQDWETLVHRAHAAGIPAPRIAQLTGIDPVDIGRLT-r......
M3C040_9ACTN/1-140 ..........................MTDDAYIVLFDDPAVS..LGVPLAAVEDAAFMDTPAVRAWLEAQGVTVTSPGLRLLPPEETSAVPEGAERLPVPLGDEELSRVRQLNAPYDVARMEEELLAYRSCAEGREALLARAVAAGVPAHRIAELTGEDLTTVKALV-h......
A0ACQ1_STRA7/10-149 ..........................MTDDAYLVLLDGTAVT..LGVPPAAVGDLACMETPAVRAWLDAQGVGASSAGLRLVPPEDTAAVPEGAERLPVPLSEEELSRVRHQAAPESVARLEDELLAYRTCADGREALLVRALAAGVPAHRVAQLTGEDLSTVRAIA-v......
A0A5J6HPA0_STRAD/1-140 ..........................MADDAYLFLLPDRRPR..LGAALAALGGLECTETPAVHGWLQAHDVSVSSEQVRILPAEAEALIPEDAERLPVPLSEEEALRVQQECAPQAVTDMESELLEYRDTTQDWEALVHRALTAGIPAQRIAQLTGIDPQDIGRL--tt.....
A0A0J7AL03_9ACTN/1-140 ..........................MTDDAYLFLAMTSDGW..QGTPLALIGELECLETPAVRAWFTAQGVSPASPAVRVVPPEQTGLIPEGAERLPVPLGEEELERVRRATATDRVAGIEEELLAFRDSEDNRDGLLRRALAAGVPAHRIVELSGVDPTTLSSAS-r......
A0A2G9DK31_9ACTN/1-140 ..........................MTDDAYLFLLDDVSSS..LGVAPAAVGDLACMETPAVHGWLDAHGITRTSPHLRLLPPEETAAIPEGAERLPVPLSDEETSRLRHQLVPEPLARIEEELLSYRDCADGRDGLIGRALAAGVPPHRIAELTGVDPATVTAAA-d......
A0A3N6I8A2_9ACTN/1-140 ..........................MDHDARLFLLPDGYPL..VGAALAAVGALACAETPAVHGWLQAHGVSASAERVRILPADAEALIPEDAESLPVPLSEEEALRVHQECAPKAIADLEAELVGFREMPKDREALVHRALTAGIPAPRIVQLTGLTPQEISGL--iq.....
A0A100Y6T5_9ACTN/1-140 ..........................MTDDAYLFLLDETATP..LGVPPGSVGDLACLETPAVRAWLDAHGVAVTSPRLRLVPPEETAAIPEGAERLPVPLGDEELSRLRHGNAPESVARLEEQLLAYREYTDGRDALLGRALAAGVPLARIVELTGEEPRTVAAAA-r......
A0A3R8TBF5_9ACTN/1-140 ..........................MTDDAYLFLLDDASAR..LGVPPAAVGELACMETPAVRAWLHAQGTTATSPHLRLLPPEETAAVPEGAERLPVPLSDEELSRVRHELAPDALAGVEEELLAYRDCADGRDGLIGRALAAGVPPHRIVELTGVDPATVTAAAQ.......
C9YVR7_STRSW/7-146 ..........................MTDDAYLFLLDDVSAP..LGVAPAAVEGLTCMETPAVRAWLDAQGSAPNSPHLRLLPPEETAAIPEGAERLPVPLSDEELSRVRHRLTPEPLARVEEELLAYRDNADGRDGLIARALAAGVPPHRIVELTGVDPATVTAAA-n......
A0A1A5NUG5_9ACTN/1-140 ..........................MTDDAYLVLLNGTAVT..LGVPPAAVGELACMETPAVRAWLQAQGVTVTSPGLRLLPPEETAALPDDAERLPVPLGEEELSRVRLHTAPHDIARMEEELLAYRSSADGREALLVRALAAGVPAHRIAELTGEDLASVKALA-h......
A0A1J4Q8Q5_9ACTN/1-140 ..........................MADDACLFLLPERHPR..LGAALSAVGELDCAESPAVLGWLHAHGTPASSERVRIVPAGSEVLIPEEAERLPVPLSEEETLRVEHACAPASLTDMESELLSFRDTTHDWQSLVHRALTAGVPAPRIAQLTGLDPRDIVQA--vg.....
A0A5Q4SX13_9ACTN/1-140 ..........................MTDDAYLFLVDSTAVT..LGVQPTGVGGLTCMDTPAVRAWLDAQGVDATSPLLRILPPEETAAVPEDAERLPVPLSEEELARVRGGAALPAATEIEQQLLAYRSLADGREDLIRRALSAGVPAHRVAELSGEDLAAVKAAA-g......
A0A0L8L572_9ACTN/1-56 ........................mm----------------..----------------------------------------------------------------------SDEQAASEKELADFRATLEGRDDMVRRARAAGLSKNRIHVLSGIARTTIDRI--in.....
A0A0F5VJR7_9ACTN/1-140 ..........................MADDALLFVLPERHPR..LGAALATVGDLECAETPAVRGWLDAHGVPASSECVRIVPAGAEVLIPEDAERLPVPLTQEETVRVEHACAPQSVTDMESELLNFRDTTQDWQSLVHRALTSGIPAPRIAQLTGLDPQDIVQAV-q......
A0A2S9Q2U8_9ACTN/1-142 ..........................MTDDAYLYLSDGRVTTgaPGVPLSAVGGLECLETSAVQAWFGAQGVAADSPALRLVVPEETPAIPEEAERLPVPLTGEELARARQAAASGVRSSVEAELMAYQNCAGDRDELLRRAVASGLPAHRIAELTGLDPATVAAAA-g......
A0A089X3P7_STRGA/1-140 ..........................MTDDAYLVLLPGTTTA..LGVPPAAVGDLACMDTPAVQAWLQAQGVTADSPELRLVPPEETAAVPEDAERLPVPLGDEELSRLRHHAAPPDLARLEEELLAYRTCTDGRNALLTRALAAGVPAHRVAELTGEDLATVKAAT-g......
A0A0M8QL01_9ACTN/1-140 ..........................MTDDAYLVLLDDADGP..LGVPLTAVGELACLDTPAVRAWLGAQGVTVTSPRLRLLPPEETGAIPEGTERLPVPLGAEELSRLRGELTPPDQARVEEELLAYRSCTNGRDGLLTRALATGVPAHRIAELTGEDLTTVKAAA-h......
A0A510TH50_9ACTN/1-140 ..........................MADEALLFVLPERHPR..LGAALSAVGELECADSPAVQGWLHAHGLPASSEHVRILPAGSEVLIPEEAERLPVPLGEEETLRVEHACAPRSVTDLETELVNFRDTTQDWQSLVHRALTAGIPAPRIAQLTGLDPQEIVQA--vg.....
A0A1D8FVQ9_9ACTN/1-141 ..........................MTDDAYLFLTDDTAAT.tLGVPPASAGNPAILETPAVRAWLDAHGVSATSPRLRLVPPEETAAIPEDAERLPVPLSEEELNRLRLQEAPEPHARLEEELLAYRECSDGRDALLGRAVAAGVPVERIVELTGEDPAVVAAVA-r......
A0A7K2XF81_9ACTN/1-140 ..........................MTDDAYLFLADTTAGSgwQGTPVSLVGELECLETPAVRAWLDAHETDVASPVLRIVPPEQTGMIPEDAERLPVPLDGEELERVRRAGATDPVAAVEEELLAYRDSKEGRDDLLHKALAAGIPAHRIVELSGVDPTAL-----ptp....
A0A0Q9AR65_9ACTN/1-140 ..........................MTDEAYLFLPDDAAAA..LGVAPSAVGDLACMDTPAVQAWLDAQGVSATSPRLRLLPPEERAAVPEGAERLPVPLSDDELSRVRHGLAPASLAQVEEELLAYRDCTDDRDALIGRALAAGVPPHRVVELTGMDPAAVTAA--gg.....
A0A2P8QFY2_9ACTN/1-140 ..........................MTDDAYLFLLDDAAVR..LGVPPAAVGDLACMETPAVRAWLDAQGTTATAPELRLLPPEETGAVPGGAERLPVPLSDEELGRVRARTGPEAIARVEEQLLSYRDITDGRDELIGRALAAGVAPHRIVELTGEDPATVTAAA-g......
A0A2U9PBC3_STRAS/1-140 ..........................MTDDAYLFLVDGAAEG..PGVPPAELGEPACMDTSAVSAWLAAHDVTAVSPRLRIVPPEETDLIPSGAERLPVPLSEEELTRLRRRQAPAATTAIEDELLAYRDCADGRDELLARALAAGVPAHRVAELTGEDLRVVQAVAQ.......
A0A7K2JIY9_9ACTN/1-140 ..........................MTDDAYLVLLNGPDLA..LGTPPAALGELACMQTPAVRAWLDAQGVTASSPALRLLPPEETQAIPEGAERLPVPLGEEELSRLRHRAAPENVARLEEELLAYRSCADGRETLLARALAAGVPAHRIAELTGEDLTAVKAIA-h......
A0A0N0ANE4_9ACTN/1-142 ..........................MTDDAYLFLVETSPGPgwQGTPVSLVGELECLRTPAVRAWLGAHETDVASPALRIVPPEQTGMIPEDAERLPVPLDGEELERVRRAGATDPVAAVEEELLAYRDSKEGRSALLSKALAVGVPAHRIVELSGVDPASLP----sspr...
A0A7W7U861_9ACTN/1-97 ..........................MADDAFLFLLHERHPR..LGAALAAVGDLECSETPAVHGRLQAHGVSASSEEVRILPFDAAEFIPEGAEQLPIPLSPDETVRVEQACAPRSV--------------------------------------------------ptwrpte
A0A117QLW7_9ACTN/1-140 ..........................MTDDAYLALLTGPGAT..LGVPPAAVGELAFMDTPAVRAWLDAQGVTPTSPELRLLPPEQTAALPEDAERLPVPLGDEELSRLRHETAPQDVARLEQELLAYRDCADGREALLARAVAAGVPPYRIAELTGEDLAAVEAVA-g......
A0A4P6U401_STRSO/1-140 ..........................MADEAYLFLLPDRHPS..LGAAMAAVAPLECDQTPAVRGWISAHDVAPSSEQLRILPAGSEILIPEEAERLPIPLTPEEEVRVQQECAPQSVTDMERELLDFRDATQGWETLVHRALTAGVPAPRIARLTGLDPQEIGRL--tg.....
A0A6H0CEI2_9ACTN/1-140 ..........................MTDDACLVLKSDAMAA..PGVPPTAVGDLAFLETPAVRAWLQAQGVTETSPDLRLVPPEETAAIPEDAERLSVPLGEEELSRLRHHTAPPDRARLEEELLGYRSCTDGRDALLARALAAGVPAHRVAELTGEDLATVEAAT-r......
A0A0U3N4J8_9ACTN/1-140 ..........................MTDDAYLFLLGDASAQ..LGVSPAAVGDLACMDTPAVRAWLDAQGSTATSPHLRLLPPEETASIPEGAERLPVPLNDEELSRVRQAMSPEPHARLEEELLAYRDCADGRDALIGRALAAGVAPHRIVELTGVDPATVTAAA-n......
A0A7J0CF33_9ACTN/1-140 ..........................MDHDARLFLLPDRYPR..VGAALGAVGALACTETPAVHGWLQAHGFSAASEEVRILPADAEALIPEDAESLPVPLSEEEASRVHRECAPKPVAELEADLRDFRETTREWEALVHRALTAGIPAPRIAQLTGLSPQEISGL--iq.....
A0A1Q5LPD3_9ACTN/1-140 ..........................MADDAYLFLLPDRQPR..LGAALAAVGALECAETPAVRAWLQAHEVSASSDHLRIVPAELEAFIPEEAERLPVPLSEEEAVRVHQECAPQSVTEVESELLEFRDTTHDWEALVHRALTAGIPAPRIAQLTGLDPQDIGRL--iq.....
A0A7W9Q1C4_9ACTN/1-140 ..........................MADEALLFVLPERHPR..LGAAMSAVGELECSQSPAVLGWLGAHGIPASSERVRIVPAGAEVLVPEDAERLPVPLSEEETLRVEHACAPESVTDMESELIGFRDTTQDWRSLVHRALTAGIAAPRIAQLTGLDPRDIVQA--vd.....
A0A176L0R6_9ACTN/1-140 ..........................MADDAYLILLSARHPL..LGAAVAAVGTLECAETPAVHGWLSAHGVHASSELVRILPAGAETLIPEDAERLPVPLSEEEAVRVQQECAPPSVTDMERQLLDFRDATHDWEALVHRALTVGIPAPRIAQLAGLDPQEICRLT-r......
A0A117RG42_9ACTN/1-140 ..........................MTDDAYLFLVDETTAH..LGVPPAALGELSCMDTAAVVAWLAAQKVTATSPHLRIVPPEEREAIPADAERVPVPLSDEELSRLRSRTAPEATVPLEEELRAYRDCTDGRDELLTRALAAGVPAHRIAELTGEDLGTVRAAG-q......
F3NGP7_9ACTN/1-140 ..........................MTDDAYLVLLDGPAGA..LGVPLAAVGEPACMATPAVQGWLDAQGVTPSSPRLRLLPPEETAAIPEGAERLPVPLDGEELSLLRHRAAPQDISRLEEELLAYRSHAEGREELLARAAAAGVPAHRIAELTGEDLVAVKAST-s......
A0A4S2SQV0_9ACTN/1-140 ..........................MTDDAYLFLATTASGW..QGTPLALVGELECLDTPAVQAWFAAQGVSPASPSVRVVPPEQSRLIPDGAERLPIPLGAEELEEVRRATATDSVASAEADLLAFRESEDNRDAVLRRALAAGVPAHRVIELSGVDPTTLSSAS-q......
V4J281_9ACTN/1-140 ..........................MTDDAYLVLLEGPAVP..LGTPLAATGPLACLDTPAVRAWLAAHEVTATSPRLYLVPPEETAALPEDAEKLPVPLSPEELSTVRTRNAPEPVAGVERELRAYRSCTEDREALLRRALAAGVPAHRVAELTGEELTAVKAAA-a......
A0A1Q4ZPK8_9ACTN/1-140 ..........................MADDAYLFLLPDRHPR..LGAALAAVGALECAQTPAVLGWLQAHGVSASSEQVRILPAAAQAFIPENAECLPVPLSEEESLRVQQESAPQSVTDMESELLEFRQTTQDWEGLVHRALTAGIPAPRIIQLTGLDPQDIGRL--tv.....
V6L0D2_9ACTN/1-140 ..........................MADDAYLFLMPDARPR..RGAAVVAVGDLECLETPAVQGWLGAHGADAASEQVRILPAEAAESLPEDAETLPVPLGPEETERVRRSCAPQQTAHVEEELVAYRDTAQEWRGLVHRALDAGIPEHRIAQLTGLQPGAVADAAQ.......
A0A101SXN3_9ACTN/1-140 ..........................MADDALLFVLPERHPR..LGAALSSVGELECAGSPAVLGWLHAHGIPGSSERVRIVPAAAEVLVPEEAERLPVPLSEEETLRVEHACAPKSLTDMEAELLSFRDTTQDWQSLVHRALTAGIPAPRIAQLTGLNPQDIVQA--vg.....
A0A2U3A0A3_9ACTN/1-140 ..........................MTDDAYLVLIDDTAPN..LGVPPAAIGEPACMETPAVRAWLDAQGVSATSPELRLLPPEETAAIPEDAERIPVPLGEEELLRLRHHLAPENLARLEEELLDYRSRTEGRDALLTRALAAGVPAHRVAELTGEDLAVVKGM--vr.....
A0A3G2J797_9ACTN/1-140 ..........................MTDDAYLFLADDPAGT..LGVPPAATEPLSCMDTSAVRAWLDAQGVSATSPRLRVVPPEDTAAIPAEAERLPVPLSDEELSRLRHRTAPETLAEVETDLLAYRDCAHGRDELLARAVAAGVAPHRIAELTGEDPAVVRAAA-l......
A0A2W2M5E4_9ACTN/7-74 hrtiasatsvrvsqslagrrvrvshp----------------..----------------------------------------------------------------------------------NARSTTQDWQSLVHRALTAKIPAPRIAQLTGLDPQDIVQAA-g......
A0A6G2VT57_9ACTN/1-140 ..........................MTDDAYLFLVDDPAER..IGVPPAEVGPLACMETPAVRAWLDAQGVSALSPRLRLMPPEETGAIEADAERLPVPLGEEELSRLRHGTAPKALVGIEGELLAYRDCAEGRDELLTRALAAGVAPHRIAELTGEDPAVVRAAA-t......
B4UX69_9ACTN/1-140 ..........................MTDDAYLFLVMTEAGW..QGTPLALVGELECLDTPAVQAWFTAHGVNPASPAVRVAPPEQTGMIPKEAERLPVPLSEEELERIRRATATDSVASVEEDLLAFRDSEDNRDDLLRRALAAGVPAHRIVALSGVDPTTLSSAS-q......
A0A0N1GUD2_9ACTN/1-140 ..........................MTDEAYLFLLDDADVP..LGVAPATVGDLACMDTTAVRAWLNAQGSTATSPRLRLLPPEERTAVPEGAERLPVPLSEEELSRVRHRTASAAHTRVEEELLAYRDCADGRDELIGRALAAGVPPHRIVELTGVDPATVTAAA-g......
A0A7L4XV37_9ACTN/1-140 ..........................MADDAYLFLLPDRHPR..VGAALAAVGALECAQTPAVQGWLHAHGVPASSEQVRILPAEAEAFIPDGAERLPLPLGEDEALRVQQECAPPSVTDMESELLDFRETTQDWESLVHRALTAGIPAPRIAQLTGIDPHDIGRLA-m......
A0A7K2QMW1_9ACTN/1-118 .........................l----------------..-------IGELECLETPAVRAWFTAQGVSPASPAVRVVPPEQTGLIPEEAERLPVPLSEEELERVRRATATDRVAGIEEELLAFRDSEDNRDGLLRRALAAGVPAHRIVELSGVDPTTLSSAS-r......
A0A1V6MXR1_9ACTN/1-140 ..........................MSDDALLFVLPERHPR..LGAALAAVGELECAGTPAVRGWLQAHGVPASSEYVRIVPAGAEVLIPEDAERLPVPLSEEETVRVEHACAPPSVTDIESELLTFRDTTQDWRSLVHRALTSGIPAPRIAQLTGLDPQDIVQA--vg.....
A0A1D2I991_9ACTN/1-140 ..........................MTDDAYLVLLNGTAVT..LGVPPAAVGELACMETPAVRAWLQAQGVTATSPGLRLVPPEETSVLPDDAERLPVPLGEEELSHVRRHAAPHNVARLEEELLAYRSYSDGRDALLVRALAAGVPAHRIAELTGEDLVTVKALA-r......
A0A7K3DJ58_9ACTN/1-140 ..........................MADEAYLFLLSDQDPR..LGAALAAVGSLECAETPAVHGWLQAHEVAAGAEQVRILPADEEAIIPGDAERLPVPLSEEEAVRVRQACAPRSVTDVEGELLGFRETTQDWEALVLRALTAGVPPARIAQLTGLDPEDVGRL--tv.....
A0A1Q5KGE5_9ACTN/1-140 ..........................MTDDAYLFLVEDPDSP..LGVPVPALGELSCMETASVRAWLHAQGVPATSPCLRVVAPEDTDDIPGGAERLPVPLSDEELSRLRHHRAPETVAAVENDLLAYRDCTDGRDELLARALAAGVSPHRIARLTGEDLAAVTAAA-g......
A0A0M8XR50_9ACTN/1-140 ..........................MADDAYLLLLPDRHPL..LGAAMAAVGPLDCAETPAVQGWLSAHGVQASSEQVRILPADAEVLIPEDAERLPVPLSEEEAVRVQQECAPASLTDMERQLLDFRDTTQGWEALVHRALKAGIPAPRIVQLTGLDPQEIGRLT-r......
D5ZVT0_STRV1/1-140 ..........................MTDDAYLVLLNGTDLT..LGVPPAAVGELACMETPAVRAWLHAQGVTAASPGLRLLPPEETAAIPDDAERLPVPLGEEELSRVRHHAASHGVARLEEELLAYRSCADGRDTLLTRALAAGVPAHRVAELTGEDLATVKALA-h......
#=GC seq_cons ..........................MTDDAYLFLLs-ssst..LGss.AAVG-LsCh-TPAV+AWLsApGVoAoSPpLRlLPPEpsuhIPEsAERLPVPLo-EELsRVR+psAPcslAclEcELLAYR-sscsR-uLltRALAAGVPAHRIAELTGlDPssVsuss.t......
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