#=GF ID   DUF6018
#=GF AC   PF19482.3
#=GF DE   Family of unknown function (DUF6018)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   28.60 28.40;
#=GF NC   23.10 22.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   15640177
#=GF RT   Identification and partial characterization of the nonribosomal
#=GF RT   peptide synthetase gene responsible for cereulide production in
#=GF RT   emetic Bacillus cereus.
#=GF RA   Ehling-Schulz M, Vukov N, Schulz A, Shaheen R, Andersson M,
#=GF RA   Martlbauer E, Scherer S;
#=GF RL   Appl Environ Microbiol. 2005;71:105-113.
#=GF RN   [2]
#=GF RM   16512902
#=GF RT   Cereulide synthetase gene cluster from emetic Bacillus cereus:
#=GF RT   structure and location on a mega virulence plasmid related to
#=GF RT   Bacillus anthracis toxin plasmid  pXO1.
#=GF RA   Ehling-Schulz M, Fricker M, Grallert H, Rieck P, Wagner M,
#=GF RA   Scherer S;
#=GF RL   BMC Microbiol. 2006;6:20.
#=GF DR   INTERPRO; IPR046060;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0000320) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, NRP (non-ribosomal
#=GF CC   peptide). This  family includes a protein from the cereulide
#=GF CC   biosynthetic gene  cluster from Bacillus cereus and appears to
#=GF CC   be predominantly found  in Bacilli [1,2].
#=GF SQ   8
#=GS A0A073JWF1_9BACI/58-170  AC A0A073JWF1.1
#=GS A0A0M0KNE8_9BACI/21-127  AC A0A0M0KNE8.1
#=GS A0A2C1JSQ2_9BACI/2-116   AC A0A2C1JSQ2.1
#=GS A0A0J1IAA8_NIACI/2-118   AC A0A0J1IAA8.1
#=GS A0A1H9Z8U9_9BACI/2-60    AC A0A1H9Z8U9.1
#=GS A0A6I1F4F1_9BACI/3-119   AC A0A6I1F4F1.1
#=GS A0A3S2TVM2_9BACI/1-114   AC A0A3S2TVM2.1
#=GS Q6EZZ9_BACAN/15-129      AC Q6EZZ9.1
A0A073JWF1_9BACI/58-170             .....ktgsvlnkalfsdetrgkrnlqi--------------------------------AKRYSASIILPNGEVRKYISPIKNKDAAIEDISQYVTAI.EDAIGKECVWQLDQTQVFYIGK-KHIGATQIERLK-----------aqckvlgkrvfgllfdt
A0A0M0KNE8_9BACI/21-127             ...........lmmkkaagenlaysmke-------------------------ISNTLLTKKKLTAEIRLADGSKKIYRAEEKDYKKALMEIVYYIKSL.EIGTEEKVLWRLHGEKLYRMGATV-EKPKVQGRFKKFLQYLF----eld..............
A0A2C1JSQ2_9BACI/2-116              ............................GATTLAELFNKSDVIEDCRKSVQNKVAFYE--RSRISAEIILKDGTRRYFRCRSNNQHIALGEVLAFVKSV.ETATGEQVVWRFKGENMYRMGSEKPVELSKKHKVVHFIKELFYLND.................
A0A0J1IAA8_NIACI/2-118              ............................KETISKGPVLQGNVFEESKRKAEKIIASKPILHSRHSIEIILPDGERRIFKAKSVSKEHAFNEFLVFIECL.EQGINSKVMWRYKGDKVYHFSTTINEKPSTITRLKKAIMGYFFDIE.................
A0A1H9Z8U9_9BACI/2-60               ...........................p----------------------------------------------------------KALQEASLFVESI.MRETGEQVYWKLDGEEHFRLGPHVGEQK-LKSRVKRFA-NWFFDL-ed...............
A0A6I1F4F1_9BACI/3-119              ............................KETISKGPVLQGNVFEESKRKAEKIIASKPILHSRHSIEIILPDGERRIFKAKSVSKEHAFNEFLVFIECL.EQGINSKVMWRYKGDKVYHFSTTINEKPSTITRLKKAIMGYFFDIE.................
A0A3S2TVM2_9BACI/1-114              ...........................m-NTTTNKLSINHEVFEDCRRHMET-VNVYE-RTTRMSAEIIFKNGDRRIYHAKSDSKKYAVKEVINFVKSI.EEAIGDKVMWRFKGDKNYNMSTNYQKDVSLLVRIKRDFLGYFFDI-.................
Q6EZZ9_BACAN/15-129                 eehktrmednqksyaapvmssesrarvn------------------------------QMRGCFEAEIILPDGKFQYFKPHALNEKEATQEIALYIEGIqEMKVGYVILWRFVGQQSFYSGTKIVAEP-KFRKILRKLKDYFFDYE.................
#=GC seq_cons                       .....................................................ls.h..h+sRhSAEIILsDGc+Rha+u+uhscccAlpEllhFlcul.EpulGccVhWRa+G-csY+hGoplsccsophsRlK+hlhsaFFDh..................
//