#=GF ID   DUF6072
#=GF AC   PF19549.3
#=GF DE   Family of unknown function (DUF6072)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   27.00 27.00;
#=GF TC   60.80 60.60;
#=GF NC   26.30 26.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR045718;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0000967) is described by MIBiG as an example
#=GF CC   of the following biosynthetic classes, NRP (non-ribosomal
#=GF CC   peptide) and polyketide. This family includes a protein from the
#=GF CC   calyculin A  biosynthetic gene cluster from uncultured
#=GF CC   Candidatus  Entotheonella sp. and appears to be predominantly
#=GF CC   found in  bacteria. 
#=GF SQ   15
#=GS W4L361_9BACT/1-113       AC W4L361.1
#=GS C1F4N4_ACIC5/1-142       AC C1F4N4.1
#=GS C1F4P7_ACIC5/1-79        AC C1F4P7.1
#=GS W4M9W8_9BACT/1-130       AC W4M9W8.1
#=GS A0A8J7QDQ8_9BACT/1-135   AC A0A8J7QDQ8.1
#=GS C1F4P8_ACIC5/24-165      AC C1F4P8.1
#=GS W4LSF0_9BACT/1-91        AC W4LSF0.1
#=GS C1F4N3_ACIC5/1-79        AC C1F4N3.1
#=GS W4LAX0_9BACT/1-130       AC W4LAX0.1
#=GS A0A069PFL6_9BURK/15-119  AC A0A069PFL6.1
#=GS A0A395LJQ1_9SPHN/1-100   AC A0A395LJQ1.1
#=GS A0A8A4U3U2_9BACT/1-97    AC A0A8A4U3U2.1
#=GS W4LTL0_9BACT/1-113       AC W4LTL0.1
#=GS A0A841JUR1_9BACT/2-100   AC A0A841JUR1.1
#=GS A0A346R2S8_9HYPH/22-149  AC A0A346R2S8.1
W4L361_9BACT/1-113                  ..............MANG--......GVIENGVKMVGEIVL.PGASLFLDGDIKAGTGHAAIGLAAWALLG-PARFLVSANSFSKSV.......TDEHLHTHLLGM--..-.----------LNTATTAVS..TSVSGLRKGQAGADDAAPDDSAEASAAP-a.....................
C1F4N4_ACIC5/1-142                  ..............MPQEFPedptkdKPLRAGLAFCGEYLV.PGGSHLVQGDLKGAAVHGVLGLTAGMLFGFPARLLFSSNSLRTALrrpatgpTAQAAETPAAAAQT..A.ETVPQPSPRRAPRKSSTRQ..APAKTQAKASAAKPTPAAVKKPAGSRSRK......................
C1F4P7_ACIC5/1-79                   .........mkvds-----T......QAMKTGIQFAGEVIL.PGGSNLVSGDYKAGGIYAALGLAAKAVFGVPGLLVVSASSFANAV.......TGKNL---------..-.-------------------..-----------------------------idfvksvp..............
W4M9W8_9BACT/1-130                  ..............MAEQND......DVVNRSIKLLGESLLtPGFSLLLDGQIKQGTLHTGLGLLARVALGIPGAFLVAANSYSVST.......TGKSLYVNLFNPKD..V.KDYNIKDAVKQDVAAGRSL..DEINARVAEDIEDIYEETVASLRNGRQL-d.....................
A0A8J7QDQ8_9BACT/1-135              ..............MSQEKKga.fsdSVLNRGVKIAGEALLtPGSSLLVDGQFKKGLAHVGGGLVAGLVLGPIGPLLVAANSYCQSV.......GGRNLVETFTKPND..L.RDQPLSNKVAAAVDEGVPL..EDLQQDIAEDVEDLYAERSHQNEGAD---avn...................
C1F4P8_ACIC5/24-165                 ..............MPREFPedptkdKPLRAGLAFCGEYLV.PGGSHLVQGDLKGAAVHGVLGLTAGMLFGFPARLLFSSNSLRTALrrpatgpTAQAAETPAAAAQT..A.ETVPQPSPRRAPRKSSTRQ..APAKTQAKASAAKPTPAAVKKPAGSRSRK......................
W4LSF0_9BACT/1-91                   ............mp--DS--......GAVGNVIKLAGELVL.PGASGLLDGDIKSGFGHTLLGVAGGALLGPGGILLVKANSYSYSV.......SEKHLHQHVIDL--..-.-------------------..-----------------------------fvqdqpattdepaad.......
C1F4N3_ACIC5/1-79                   .........mkvds-----T......QAMKTGIQFAGEVIL.PGGSNLVSGDYKAGGIYAALGLAAKAVFGVPGLLVVSASSFANAV.......TGKNL---------..-.-------------------..-----------------------------idfvksvp..............
W4LAX0_9BACT/1-130                  ..............MAEQKN......EVVHRSIKLLGESLLaPGFSLLLDGQIKQGTLHTGAGILARIALGIPGAILVAANSYSVST.......TGKSLYANLFDPED..V.KAYNIKDAVKQDVAAGLSL..DEINARVTEDIEDIYEEAVASLRNGRQLN......................
A0A069PFL6_9BURK/15-119             rtangtnttvvrst------......SPATNGVKLVGEAFV.PGASLLMDGNVVNGAAHVAAGIGIKMLFGPVGLLLAAADSYSKSV.......TDKYLWDHVGDL--..V.NK--AKEN-----------..-----------------------------rkakaeaasppa..........
A0A395LJQ1_9SPHN/1-100              ..............MKDEQT......EAVQLATSYAGEALV.PGGAHLVRGNLKQGGLHLVVGLAARTMFGLPGLALVSANSLVKAQ.......SGRHLTEHLGLT--..-.-------------------..-----------------------------kpkvdeeeaeestsstrkstks
A0A8A4U3U2_9BACT/1-97               ..............------......--------------M.PGTSLLLDGKIKAGALHAGGGILAKLVLGVPGLVLVAANSYSQSV.......TGQSLLQNVLHN-K..A.PDSSLKEIVEQDLASGKTP..DEIKAGLAEDVDDICAQ------------a.....................
W4LTL0_9BACT/1-113                  ..............MANG--......GVIENGVKMVGEIVL.PGASLFLDGDIKAGTGHAVVGLAAWAFMG-PARFLVSANSFSKSV.......TDEHLHTHLLGM--..-.----------LNTTTSTVS..DRVSGLWKSRAGADNASTDDSAEASAAP-a.....................
A0A841JUR1_9BACT/2-100              .....saaaplvte------......ETLGKVVKGAGELSL.PGFSLYLDRKIGEAALHTVAGLAAATVFGPLGYVLVGANSFSKSV.......SGRTLVDRLATKTA..ArESAEVTTAR----------..-----------------------------ktsak.................
A0A346R2S8_9HYPH/22-149             .......vrpdgit------......-MLANGAKIIGEAVL.PGASLLADGKFVNGVVHTALGFGARAATGPIGFAVVAADSYSKSV.......TDKHLWTHVSDIATelR.GSYRARRAARQEMAAKAPHdgAEISAEAEESDAKTTRASSK---------ttsk..................
#=GC seq_cons                       ................pt........pslpsGlKhsGEhlL.PGuSLLlDGclKsGslHsulGLuAtslhG.PGhlLVuANSaSpSV.......Tu+sLhsplhsh....h..t....p.....httth....t.hpt.http.tt...t............t.....................
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