#=GF ID DUF6083
#=GF AC PF19561.3
#=GF DE Family of unknown function (DUF6083)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 27.10 27.10;
#=GF TC 27.20 27.10;
#=GF NC 26.30 26.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 28111097
#=GF RT An Unusual Protector-Protege Strategy for the Biosynthesis of
#=GF RT Purine Nucleoside Antibiotics.
#=GF RA Wu P, Wan D, Xu G, Wang G, Ma H, Wang T, Gao Y, Qi J, Chen X,
#=GF RA Zhu J, Li YQ, Deng Z, Chen W;
#=GF RL Cell Chem Biol. 2017;24:171-181.
#=GF DR INTERPRO; IPR045729;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC00001735) is described by MIBiG as an
#=GF CC example of the following biosynthetic class, other. This family
#=GF CC includes a protein from the pentostatine biosynthetic gene
#=GF CC cluster from Streptomyces antibioticus and appears to be
#=GF CC predominantly found in Streptomyces [1].
#=GF SQ 143
#=GS A0A1X4ICH9_9ACTN/25-135 AC A0A1X4ICH9.1
#=GS A0A445N6H7_STRNE/48-164 AC A0A445N6H7.1
#=GS A0A553ZQ58_9ACTN/1-62 AC A0A553ZQ58.1
#=GS G2N9Q7_STREK/23-134 AC G2N9Q7.1
#=GS A0A2G9DT74_9ACTN/1-86 AC A0A2G9DT74.1
#=GS A0A7Y0B7R6_9ACTN/22-133 AC A0A7Y0B7R6.1
#=GS A0A2A2Z546_9ACTN/22-131 AC A0A2A2Z546.1
#=GS A0A0F4JCI8_9ACTN/3-113 AC A0A0F4JCI8.1
#=GS A0A250VUT9_STROL/23-134 AC A0A250VUT9.1
#=GS A0A117RYR6_9ACTN/18-129 AC A0A117RYR6.1
#=GS S3AQY6_9ACTN/41-155 AC S3AQY6.1
#=GS A0A2M9JMJ7_9ACTN/1-86 AC A0A2M9JMJ7.1
#=GS A0A1D2IL20_9ACTN/1-67 AC A0A1D2IL20.1
#=GS A0A7M2SAQ2_9ACTN/23-134 AC A0A7M2SAQ2.1
#=GS A0A0N1NQA0_9ACTN/1-115 AC A0A0N1NQA0.1
#=GS A0A852ZZZ9_9ACTN/4-104 AC A0A852ZZZ9.1
#=GS A0A1C5C930_9ACTN/17-132 AC A0A1C5C930.1
#=GS A0A0L8QKB6_9ACTN/16-127 AC A0A0L8QKB6.1
#=GS A0A1H0U8V4_9ACTN/21-132 AC A0A1H0U8V4.1
#=GS A0A1B1AZN1_9ACTN/23-135 AC A0A1B1AZN1.1
#=GS A0A1Q5LKL9_9ACTN/30-118 AC A0A1Q5LKL9.1
#=GS A0A1M5RZR9_9ACTN/33-144 AC A0A1M5RZR9.1
#=GS A0A2D3UIW1_STRC0/24-135 AC A0A2D3UIW1.1
#=GS A0A4Q6II36_9ACTN/1-111 AC A0A4Q6II36.1
#=GS A0A1Q4ZP24_9ACTN/17-132 AC A0A1Q4ZP24.1
#=GS A0A7H8J0L3_9ACTN/1-100 AC A0A7H8J0L3.1
#=GS A0A540W458_9ACTN/31-139 AC A0A540W458.1
#=GS A0A1S2QFC9_9ACTN/1-110 AC A0A1S2QFC9.1
#=GS A0A0B5DBW7_9ACTN/23-134 AC A0A0B5DBW7.1
#=GS A0A3R9UUC4_9ACTN/2-104 AC A0A3R9UUC4.1
#=GS A0A2M9JGX5_9ACTN/21-131 AC A0A2M9JGX5.1
#=GS A0A6B2S7L0_9ACTN/1-86 AC A0A6B2S7L0.1
#=GS S3B1L8_9ACTN/1-113 AC S3B1L8.1
#=GS A0A1M5V9K0_9ACTN/21-132 AC A0A1M5V9K0.1
#=GS S4NGG2_9ACTN/1-86 AC S4NGG2.1
#=GS A0A0M8XAV4_9ACTN/34-150 AC A0A0M8XAV4.1
#=GS B5HBR6_STRE2/49-154 AC B5HBR6.1
#=GS A0A4S2SQ95_9ACTN/2-105 AC A0A4S2SQ95.1
#=GS A0A1Q5G5I0_9ACTN/17-134 AC A0A1Q5G5I0.1
#=GS A0A4U0SAF7_9ACTN/3-113 AC A0A4U0SAF7.1
#=GS C9Z8M0_STRSW/1-113 AC C9Z8M0.1
#=GS M3DZ93_9ACTN/1-86 AC M3DZ93.1
#=GS A0A2I0SK50_9ACTN/2-59 AC A0A2I0SK50.1
#=GS D9WBK4_9ACTN/23-133 AC D9WBK4.1
#=GS A0A1M5ZGN2_9ACTN/34-98 AC A0A1M5ZGN2.1
#=GS A0A1H9XGL6_9ACTN/37-99 AC A0A1H9XGL6.1
#=GS A0A100Y2Z1_9ACTN/33-124 AC A0A100Y2Z1.1
#=GS A0A2S4Z614_9ACTN/1-113 AC A0A2S4Z614.1
#=GS A0A221P9H3_9ACTN/33-149 AC A0A221P9H3.1
#=GS A0A2M9I9P0_9ACTN/22-132 AC A0A2M9I9P0.1
#=GS A0A1Q4VI91_9ACTN/1-82 AC A0A1Q4VI91.1
#=GS A0A124IAZ2_9ACTN/23-134 AC A0A124IAZ2.1
#=GS A0A1H5BGT3_9ACTN/22-85 AC A0A1H5BGT3.1
#=GS A0A101JID9_9ACTN/23-134 AC A0A101JID9.1
#=GS B5HB02_STRE2/50-161 AC B5HB02.1
#=GS A0A1C4IH46_9ACTN/1-50 AC A0A1C4IH46.1
#=GS A0A1H0DT74_9ACTN/24-135 AC A0A1H0DT74.1
#=GS A0A3B0BWX0_9ACTN/2-97 AC A0A3B0BWX0.1
#=GS A0A0B5DMJ4_9ACTN/1-112 AC A0A0B5DMJ4.1
#=GS A0A3N5AF83_9ACTN/23-134 AC A0A3N5AF83.1
#=GS A0A239HZR8_9ACTN/28-138 AC A0A239HZR8.1
#=GS A0A1Q4VS74_9ACTN/44-157 AC A0A1Q4VS74.1
#=GS A0A6G3S0J8_9ACTN/1-86 AC A0A6G3S0J8.1
#=GS A0A117QM68_9ACTN/1-113 AC A0A117QM68.1
#=GS A0A2Z5K134_9ACTN/38-154 AC A0A2Z5K134.1
#=GS A0A1V4AF95_9ACTN/36-123 AC A0A1V4AF95.1
#=GS A0A4Q1RMC2_9ACTN/44-165 AC A0A4Q1RMC2.1
#=GS A0A550IC80_9ACTN/3-112 AC A0A550IC80.1
#=GS A0A124HQM9_9ACTN/1-112 AC A0A124HQM9.1
#=GS A0A1J4Q3C6_9ACTN/1-113 AC A0A1J4Q3C6.1
#=GS A0A2T0R8A2_9ACTN/65-171 AC A0A2T0R8A2.1
#=GS A0A7K2L3C6_9ACTN/23-127 AC A0A7K2L3C6.1
#=GS A0A1H6C997_9ACTN/35-151 AC A0A1H6C997.1
#=GS D5ZQT4_STRV1/40-156 AC D5ZQT4.1
#=GS A0A2P8Q173_9ACTN/1-99 AC A0A2P8Q173.1
#=GS A0A6B3FYX5_9ACTN/3-89 AC A0A6B3FYX5.1
#=GS A0A124ICA9_9ACTN/23-133 AC A0A124ICA9.1
#=GS A0A365ZKX2_9ACTN/28-95 AC A0A365ZKX2.1
#=GS A0A429R2G5_9ACTN/6-116 AC A0A429R2G5.1
#=GS A0A3N6DMR1_9ACTN/20-135 AC A0A3N6DMR1.1
#=GS A0A4R9ERR8_9ACTN/32-149 AC A0A4R9ERR8.1
#=GS A0A1C4QJQ2_9ACTN/1-50 AC A0A1C4QJQ2.1
#=GS A0A1G9YQP9_9ACTN/67-183 AC A0A1G9YQP9.1
#=GS A0A2A2Z442_9ACTN/1-86 AC A0A2A2Z442.1
#=GS A0A239P0F4_9ACTN/26-136 AC A0A239P0F4.1
#=GS A0A0G3UPG2_9ACTN/21-130 AC A0A0G3UPG2.1
#=GS A0A1E5P0D2_9ACTN/14-124 AC A0A1E5P0D2.1
#=GS A0A5N8XVZ8_9ACTN/1-87 AC A0A5N8XVZ8.1
#=GS L1KYN9_9ACTN/1-48 AC L1KYN9.1
#=GS A0A345SWZ7_9ACTN/22-131 AC A0A345SWZ7.1
#=GS A0A1V6MIR7_9ACTN/1-113 AC A0A1V6MIR7.1
#=GS A0A3M0I920_9ACTN/57-159 AC A0A3M0I920.1
#=GS A6WD97_KINRD/54-163 AC A6WD97.1
#=GS A0A6B2XCT6_9ACTN/23-134 AC A0A6B2XCT6.1
#=GS A0A2W2K6W0_9ACTN/21-107 AC A0A2W2K6W0.1
#=GS A0A1X4ICH0_9ACTN/4-107 AC A0A1X4ICH0.1
#=GS D9WQY8_9ACTN/31-141 AC D9WQY8.1
#=GS V4IKP9_9ACTN/99-203 AC V4IKP9.1
#=GS A0A2A4KGS1_9ACTN/23-136 AC A0A2A4KGS1.1
#=GS G2NJN9_STREK/21-136 AC G2NJN9.1
#=GS V6JV24_STRNV/32-137 AC V6JV24.1
#=GS A0A0M8YH73_9ACTN/1-109 AC A0A0M8YH73.1
#=GS A0A445NJS0_STRNE/4-100 AC A0A445NJS0.1
#=GS A0A100Y0W9_9ACTN/36-139 AC A0A100Y0W9.1
#=GS A0A1G5CV11_9ACTN/57-172 AC A0A1G5CV11.1
#=GS A0A7M3LZ68_9ACTN/43-151 AC A0A7M3LZ68.1
#=GS A0A101UAD6_9ACTN/21-131 AC A0A101UAD6.1
#=GS A0A1Q5KS37_9ACTN/34-152 AC A0A1Q5KS37.1
#=GS A0A1J4NQK6_9ACTN/1-112 AC A0A1J4NQK6.1
#=GS A0A7Y0BAL7_9ACTN/1-111 AC A0A7Y0BAL7.1
#=GS A0A505DEM1_9ACTN/1-86 AC A0A505DEM1.1
#=GS A0A561UFX3_9ACTN/61-167 AC A0A561UFX3.1
#=GS A0A3N6FF72_9ACTN/21-136 AC A0A3N6FF72.1
#=GS A0A7L4YAN5_9ACTN/1-110 AC A0A7L4YAN5.1
#=GS A0A652L5I1_9ACTN/1-72 AC A0A652L5I1.1
#=GS A0A3N5AQX2_9ACTN/3-113 AC A0A3N5AQX2.1
#=GS A0A1Q4YC39_9ACTN/17-132 AC A0A1Q4YC39.1
#=GS A0A371PQ97_STRIH/24-135 AC A0A371PQ97.1
#=GS A0A0F5VU83_9ACTN/1-113 AC A0A0F5VU83.1
#=GS A0A0M9ZQ14_9ACTN/23-134 AC A0A0M9ZQ14.1
#=GS A0A0M8QSA1_9ACTN/1-113 AC A0A0M8QSA1.1
#=GS A0A1H5JW75_9ACTN/1-97 AC A0A1H5JW75.1
#=GS A0A6B3GSQ8_9ACTN/118-221 AC A0A6B3GSQ8.1
#=GS A0A250VR64_STROL/1-94 AC A0A250VR64.1
#=GS A0A177HLD5_9ACTN/23-134 AC A0A177HLD5.1
#=GS V6JHC4_STRRC/33-149 AC V6JHC4.1
#=GS A0A2M9IA11_9ACTN/23-133 AC A0A2M9IA11.1
#=GS L7F0J0_9ACTN/45-140 AC L7F0J0.1
#=GS A0A1R1S4C7_9ACTN/25-136 AC A0A1R1S4C7.1
#=GS A0A2N5XHF7_9ACTN/27-136 AC A0A2N5XHF7.1
#=GS A0A0N0SMI0_9ACTN/23-133 AC A0A0N0SMI0.1
#=GS A0A0B5EM15_STRA4/3-114 AC A0A0B5EM15.1
#=GS A0A3R9YCB6_9ACTN/21-132 AC A0A3R9YCB6.1
#=GS A0A7X0HGR8_9ACTN/28-125 AC A0A7X0HGR8.1
#=GS A0A6B3HIK9_9ACTN/118-221 AC A0A6B3HIK9.1
#=GS A0A426UDS3_9ACTN/59-123 AC A0A426UDS3.1
#=GS Q9ADB8_STRCO/53-167 AC Q9ADB8.1
#=GS R6JST6_9CLOT/5-81 AC R6JST6.1
#=GS A0A3Q8V7V5_9ACTN/23-136 AC A0A3Q8V7V5.1
#=GS A0A1B1M113_STRLN/30-141 AC A0A1B1M113.1
#=GS R5ID68_9FIRM/1-83 AC R5ID68.1
#=GS A0A1A5P753_9ACTN/1-113 AC A0A1A5P753.1
#=GS A0A0F4JTI6_9ACTN/2-105 AC A0A0F4JTI6.1
A0A1X4ICH9_9ACTN/25-135 .....................RSLRIAPDSASRLLRCGHTTSCRECGNPVECYPG...ADD..RLVRLHP...R.ELPVAGVP.EPCRWHV...S.....RGIAHPAG....DGSS............WCRLAHDLLCPARP-..APTA...APQLSGLRRTLALCTRRLLD.............................................................
A0A445N6H7_STRNE/48-164 ....................n-KQALDEGATAT--PPPSPSTCRDCELDQDRYET...GYG..RWVLLEP...RyAPPAYSVP.VGHRWIV..rA.....DGRAVNVG....DAALpr........gaVCRIPHRLVCPCGAR.lPDDT...PRALVVLRDLNRAVVARV--fp...........................................................
A0A553ZQ58_9ACTN/1-62 ...................mr----------------------------------...---..-------...-.------VV.PRQRWQV...D.....NGVAYLNP....AAQG............ACRLPHPAVCPMVEH..-TDA...DRELEGVRRALAVRTRKAID.............................................................
G2N9Q7_STREK/23-134 ....................r-PLRVATTSPSRLLRAGQSRRCPQCGNRIDLYPR...TDG..RPTALHP...A.ELATAQVP.APCRWHL...S.....SGIAHPHD....DGRT............WCRIPHAVLCPQRTP..ICRI...SRPLESARRQLAVRTRRLID.............................................................
A0A2G9DT74_9ACTN/1-86 ...................ma---------------------------------T...LDH..DWVMLEP...DlHVLAHLVP.ADHRWIT..lS.....DGRVTVYG....VWPPdp........sqRCRIEHRLACSGQRL..PD-L...WPWLSALRQENQRRAERLA-a............................................................
A0A7Y0B7R6_9ACTN/22-133 .....................RTLTVAHDSPSRLLRCAQSARCPRCGNRIDRHTT...TGP..RPVSLHP...G.ELPTELVP.ADYRWHL...A.....SGVAYPAG....DGSP............WCRIAHPAVCPAGTH..PADL...PDSLNAISRKLALHTRHLID.............................................................
A0A2A2Z546_9ACTN/22-131 .....................RSLRVSGDSASRLLRCGQSDRCRDCGNRIEWYHR...TNE..RPVRLHP...D.ELPAEKVP.AACHWHV...S.....RGVAHPAG....DGST............WCRLPHTLVCPARDA..--PP...APELAGLRRALAVNTRRLID.............................................................
A0A0F4JCI8_9ACTN/3-113 ................dyqde---------PPR-LRAG-QPHCPHCGLPVDRTAT...DEH..DWVLLEP...DmTPLAHVVP.PQHRWIT..rS.....DGRVTVYA....VSPPdp........tqRCRIEHRLACAAQPL..PD-L...WPWLTTLRTENHRRARRRA-e............................................................
A0A250VUT9_STROL/23-134 ....................r-PLRVTAASPSRLLRAGQSGRCRRCGNRIDFYQR...ADQ..RPIALHP...A.ELATTHVP.DSCRWHL...S.....CGVAIPHG....DGSA............WCRIPHAVLCPDRTP..TAQT...GPHIEAVRRQLAVRTRRLID.............................................................
A0A117RYR6_9ACTN/18-129 ....................r-PLRVAATSPSRLLRTGQSGRCRGCGHRIDWHPR...ADQ..RPIALHP...A.ELATAHVP.ASCRWHL...S.....SGIALPHG....DGSA............WCRIPHAVLCPHRTP..TAPA...GPHIQALRRQLAVRTRRLID.............................................................
S3AQY6_9ACTN/41-155 ...................nr--QALDEYAAAP--PPPAEPRCRHCETLQDRYET...GYD..RWVLLEP...GtALPWHLIP.LGHRWTL..aG.....DGKAVNLG....TRRLpg........gvRCRFPHALVCPCDEQ..PEVL...RPFFTALWEEDEHRYR----shr..........................................................
A0A2M9JMJ7_9ACTN/1-86 ...................ma---------------------------------T...LEH..DWVLLEP...GmRVLAHLVP.AEHRWIE..lS.....DGRVTVYG....VCPVdg........tqRCRIEHRLACAGQEL..PD-L...WPWLTTLRNENGRMARRQ--ep...........................................................
A0A1D2IL20_9ACTN/1-67 ....................m----------------------------------...---..-------...-.-------P.GGHRWHL..dT.....DGTAWNGG....LDEPlp........gaTCRVPHRLACPGLAL..DEIR..pWRWLETVRRFNTERARRK--ag...........................................................
A0A7M2SAQ2_9ACTN/23-134 ....................r-PLQVAATSPSRLLRTGHCSRCRMCGNRIDLYQR...TDQ..RPIALHP...T.ELPVAHIP.APCRWHL...S.....CGIAHPHS....DGSA............WCRIPHAVLCPHRTA..PAQL...SSHIEELRRQLAVRSRRLVD.............................................................
A0A0N1NQA0_9ACTN/1-115 .................mgav------DHEGSRLWGRGRRYTCPYCGLPQDRVLT...LEQ..DWVLLEP...GvDVLAHLVP.AEHRWIV..lS.....DGRVTVYG....VCPPvp........tqRCRIEHRLTCAARPL..PD-L...WPWLTAMRAENARRAERS--rs...........................................................
A0A852ZZZ9_9ACTN/4-104 ...............rhdsgt----------------ARIGSCGDCGLPVEYRTA...LGG..DRVALQP...G.EFPARAVP.PYLHRHL...S.....RGVVYEGA....EPVH...........dWCRIPHDAVCPAQE-..-EPR...HPGLREMHRRLAVRSRKA--re...........................................................
A0A1C5C930_9ACTN/17-132 ...................al--QAALEGATAP--PPPAAPDCSFCDLPQDRYPT..hYEG..HWVLLEP...RiVVPAHTVP.PRRRWII..tS.....DGAAMNLW....DAAPlp........gaQCRIAHRMVCPYLPR..ED-P...PLWATALRQENEHRAQRLF-n............................................................
A0A0L8QKB6_9ACTN/16-127 .........ratrtatpvpdp-----------RTPKPGARTGCSWCGGAAAWHRT...VRG..RWILIEH...G.TWPLTAIP.AGKRWRI..aG.....DGTAVNLG....SAAPs..........dTCRITHFDICPARP-..APIG...SDILLTLWQRNS--------qqptd........................................................
A0A1H0U8V4_9ACTN/21-132 ....................r-PLQVAATSPTRLLRAGQSSRCRRCGNRIDLYQR...ADQ..RPIALHP...T.ELTATLVP.EPCRWHL...G.....GGIAYPHG....DGSP............WCRIPHAVLCPCRTP..LCRT...GPHLNAIRRHLAVRTRRLTD.............................................................
A0A1B1AZN1_9ACTN/23-135 .....................RSLQIASNSPSRLLRAGQTSRCRHCGTRIDWYPR...HDD..RPIALHP...T.EVATADVS.QACRWHL...S.....GGIAHPHD....DGSG............WCRIPHAALCPQQTP..HPRT..sSPRLTPLRRELALRSRRLID.............................................................
A0A1Q5LKL9_9ACTN/30-118 ............aatlrasip--------APRP-PRTGSLMTCRLCGAEARWHRT...VHG..RWVAIEP...G.ERPTAGVP.RGERWYV..aG.....DGTAVQLR....GAAPs..........dTCRVSHFSVCA----..----...--------------------gr...........................................................
A0A1M5RZR9_9ACTN/33-144 ....................r-PLRVAATSPSRLLRTGQSGRCRWCGNRINWHQR...ADQ..RPIDLHP...T.ELTTAHVP.ASCRWHL...S.....SGIAHPHG....DGSA............WCRIPHTVLCPHHPP..TAPT...SPHIEAVRRQLAVRTRRLID.............................................................
A0A2D3UIW1_STRC0/24-135 .....................RTLRVTADSPSRLLRTAQGTACRDCGNRIDWYTR...SHG..RPIGLHP...H.ELPAAAVP.DACRWHV...A.....SGIAYPSH....DGSA............WCRIRHTLLCPASEA..PEPL...TPPLAELRRRFALRTRRLLD.............................................................
A0A4Q6II36_9ACTN/1-111 ................mgllr-------GEPRR--PKGGQLRCPYCGLLQAHVAT...LEQ..EWFLLEP...DmTPLAHMVP.AEHRWIE..lS.....DSRVTVYG....VCPPdp........lqWCRIEHRLACSAQPL..PD-L...WPWSTTLRAENGRRV-----tpv..........................................................
A0A1Q4ZP24_9ACTN/17-132 ...................al--QAACEGATAP--PPPTPPVCPRCALPQDRYPT..lYPQ..TWVLLEP...GiTVASHRVQ.PRRRWLI..tP.....DGIAWNTW....DAEPip........gsRCRISHRSVCPWSAA..D-DL...WPWGTALRRENARRAQRLF-n............................................................
A0A7H8J0L3_9ACTN/1-100 ....................m-------------LRTAQQSRCSDCGNHIEWYDC..tASH..NPVPLHP...H.ELPAAAVP.PSQRWHI...D.....TGIAHPSG....DGSP............WCRVRHRALCPTTPA..-QPG...NPTLDTLRRNLALTSRRLQD.............................................................
A0A540W458_9ACTN/31-139 ..............rgqamae-------AAAAD---HKPTGRCRYCQREAAWHPT...VRG..RWILLDL...D.DHPAHCVP.NGRRWQV..dP.....RGTVATVT....PSAVi..........rMCRIAHWDVCPGLPA..--PR...DVYLESVRHRLI--------tgqsrnr......................................................
A0A1S2QFC9_9ACTN/1-110 .....................--MRVHPDSPTRLLRCAQRARCRECGNPVEWYHR...GRD..RPVPLHP...Q.ELPAAEMP.AAYRWHV...S.....SGLAHPAG....DGST............WCRLTHAVVCPARDA..PCDI...TPALTWLRRSLAVNTRRLTD.............................................................
A0A0B5DBW7_9ACTN/23-134 ....................r-PLRVAATSPSRLLRAGQSGRCRRCGNRIDIYQR...TDQ..RPIALHP...A.EVATEQVP.DSCRWHL...A.....GGIAHPHG....DGSA............WCRIPHIVLCPGSTP..TPRL...GRRLEEVRRQLALHTRRLID.............................................................
A0A3R9UUC4_9ACTN/2-104 ..............sskyahl----------------GRLGHCWRCGDSVQGYPD...HDG..QEVVLDV...R.EAPTHLVP.EDLRWRV..nG.....NGIALPLG....WTDPt..........dTVRIRHEPVCIASP-..RPGP...EPLRKHLNR-----------ahpvarghe....................................................
A0A2M9JGX5_9ACTN/21-131 .....................RALHVDPDSPTRLVRTAQSVTCRLCGNRFEWYQR...SDG..RPIGLHP...T.ELTTRTVP.ARCRWHL...S.....RGVAHPAG....DGSA............WCRIPHHLICPGLD-..TTTL...TPPLNELRRQLALRTRRLID.............................................................
A0A6B2S7L0_9ACTN/1-86 ....................m--------------------------------PT...LDD..GTVMLEP...DmMVAAHLVP.ADHRWIV..lP.....DGQVAMYGvspvDGAQ............RCRLEHRLACPRQEL..PD-L...WQWLTTLREENARRSERLP-d............................................................
S3B1L8_9ACTN/1-113 ................mgale-------EKPRR--LKGGRIRCPRCGLMQDRVLT...LEY..DWVLLEP...AvHPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHSLACPAQPL..PD-L...WPWLTTLRDQNARQLERL--sa...........................................................
A0A1M5V9K0_9ACTN/21-132 .....................RSLCVDPDSPSRLLRCAQRDRCRECGNQAEWYQR...VRD..RPVLLHP...Q.ELPTAAVP.AEYRWHV...S.....SGLAYPSG....DGSA............WCRLTHASICPAQDT..ADAA...ASELTRLRRTLAVNTRRLVD.............................................................
S4NGG2_9ACTN/1-86 ...................ma---------------------------------T...LEQ..DWVLLEP...GvTILAHLVP.AEHRWIE..lS.....DGRVTVYG....VCPPdg........sqRCRIEHRLACAKQPL..P-DL...WPWLTALRNENARAAERR--sg...........................................................
A0A0M8XAV4_9ACTN/34-150 ....................r-VQAALDGAAGP--EPPRPPVCPHCGLTGDRRPT...YAG..QHVLLEP...RlTVPAHLVP.GGHRWHL..dG.....NGTAWNGG....LDEPpp........gaTCRIPHQLACPGLAL..DEIR..pWRWLTAVREHNALAARHRAD.............................................................
B5HBR6_STRE2/49-154 ...............daltfa---------TRTAAAAPGSATCHECGSTAERHRT...AHG..RWILIEP...G.ALAAAAVP.VGHRWRI..aG.....DGTAVGLR....SAAPs..........gTCRISHLDVCPARP-..APAH...SPALHAVWRRNAR-------qg...........................................................
A0A4S2SQ95_9ACTN/2-105 .............sskyadlg-----------------RLGHCWRCGDSVQGYPD...HDG..QEVVLDV...R.EAPTHLVP.EELRWRV..nG.....NGIALPLG....WTDPt..........dTVRIRHEPVCTASP-..RPGP...EPLRNHLNR-----------arpiarghen...................................................
A0A1Q5G5I0_9ACTN/17-134 ....................d-FQALREGATAP--PPPEPPDCPDCGLRQDRYPT..lYEG..HWVLLEP...GiAVPSHHLP.PRRRWVI..gV.....DGTAINTW....DAEPtp........gaFCHVPHHLVCPCPNV..GAAW..pWPWGAAMREENDRRSQRLF-e............................................................
A0A4U0SAF7_9ACTN/3-113 ...................rr--LWVHPENSSRLLRAGQTRRCRYCGNYVDWHYK...ADG..SPVPLVP...Q.EFPARQIP.DGKRWHL...S.....RGTVYPGD....GGSR............FCRIAHTAVCPAADE..S-DT...HPRLLPVRRHLAVHSRKLV-e............................................................
C9Z8M0_STRSW/1-113 ...............mgvlde--------KPRR--IGRGRNRCPHCGLPQDRVAT...LGQ..DWVLLEP...DmRPPAHTVP.AEYRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPKQAL..PD-L...WPWLTSLRGENARQAHRRS-d............................................................
M3DZ93_9ACTN/1-86 ...................ma---------------------------------T...LEH..DWVLLEP...DmRPLAHTVP.ADRRWIE..lS.....DGRVTVYG....VCPPdp........fqRCRIAHDLACPAQTL..PD-L...WPWLTSLRIENARRVER---gdd..........................................................
A0A2I0SK50_9ACTN/2-59 ..................swi-----------------EPPTCPTCGALVRTCPT...NYD..RWVSLAT...V.ELPAKDVP.EPFRWRL...-.....--------....----............---------------..----...--------------------tklpvrspvvtd.................................................
D9WBK4_9ACTN/23-133 .....................RSLRVDPDSGSRLLRCAVNGSCRECGNLVEWYVR...SNE..RLVRLHP...Q.ELPVSQVP.KACRWHI...S.....SGVAHPAG....DGSG............WCRLPHALLCPARA-..APPS...VPQLSGLRRSMAIRTRRLLD.............................................................
A0A1M5ZGN2_9ACTN/34-98 .......aprpdpdpddvtwi-----------------EPPLCPECGALVRIYPT...NYD..RWVSLAM...V.ELPAKDVP.EAFRWRL...-.....--------....----............---------------..----...--------------------trlpgrsp.....................................................
A0A1H9XGL6_9ACTN/37-99 ..........pdpdpddvtwi-----------------EPPICPECGASVRVYPT...SYD..RWISLAM...V.ELPAKDVP.EAFRWRL...-.....--------....----............---------------..----...--------------------trlpgrspv....................................................
A0A100Y2Z1_9ACTN/33-124 ........lrasgglprvppp--------------RTGSVMTCRYCGGRARWHRT...AGD..RWVAMEP...G.ARPVAGVP.RGRRWYI..aG.....DGTAVHLR....GAVPs..........gTCRVSHFDVCPGRA-..----...--------------------hag..........................................................
A0A2S4Z614_9ACTN/1-113 .................mgal------EKTPGR--LGSGQSRCPYCGLPQDRVAT...LEY..DWVMLEP...DmAPLAHMVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPAQPL..PD-L...WPWLTALRGENAREAQRN--ep...........................................................
A0A221P9H3_9ACTN/33-149 .....................RAQAAVDGATGP--EPPGPPRCPHCGLAGERRPT...YTD..RHVLLEP...GlVLPAHLVP.GGHRWHL..dG.....NGVAWNGG....FAEPpp........gtSCRVPHLLACPGLTL..DEIR..pWRWLSAVRGENARKVRRQA-a............................................................
A0A2M9I9P0_9ACTN/22-132 .....................RSLHVSPDGVSRLLRCGQGDRCRECGNRIEWYHR...GAQ..RPVRLHP...H.ELPAARVP.AVCRWHV...S.....SGVAYPGG....DGSS............WCRLPHAVVCPARD-..TPPP...PPELTGLRRSLAVNTRRLID.............................................................
A0A1Q4VI91_9ACTN/1-82 ...................mv------------------------------WYDR...HDG..GRIPLAP...A.RFPAHRVP.PRFRWSV...D.....MGMAAPGA....LFG-............DCFLAHPAICPAIE-..HEGL...PRDIEDVVRVLGVRMRKLLD.............................................................
A0A124IAZ2_9ACTN/23-134 ....................r-PLRVTATSPSRLLRAGQHSRCRRCGNRIDLYPR...TDQ..RPIALHP...A.ELTATQVP.ESCRWHL...S.....GGIAHPHG....DGSA............WCRIPHAVLCPRRTP..TCRP...HPCLETVRRQLAVCTRRLID.............................................................
A0A1H5BGT3_9ACTN/22-85 ....atapprpnpdpddvtli-----------------EPPRCPECGALVRVYPT...SYD..RWGSLAM...V.ELPAKDVP.AAFRWRL...-.....--------....----............---------------..----...--------------------trvp.........................................................
A0A101JID9_9ACTN/23-134 .....................RSLRVSHGGTSRLMRCGQHSRCHECGNRIEWYHRs.dPQM..AMVPLHP...H.ELPAARVP.ADCRWHV...S.....SGIAHPAG....DGSG............WCRIPHALLCPARNV..P--T...AAGLGTLRRALAVHTRRLID.............................................................
B5HB02_STRE2/50-161 ....................r-PLRVTTTSPSRLLRAGQTGRCRHCGHRIDLYQR...PDQ..RPIALHP...A.ELATADVP.ESCRWHL...S.....GGIAYPHG....DNSA............WCRIPHAVLCPHRTP..TCQA...GPRLEVIRRQLAVRTRRLID.............................................................
A0A1C4IH46_9ACTN/1-50 ...................mt----------------------------------...---..-------...-.--------.-------...-.....------LW....DAEPlp........etRCRIAHRMVCPYLP-..RDDP...WPWTTALRQENERRGQRLF-n............................................................
A0A1H0DT74_9ACTN/24-135 .....................RSLRLSESSPSRLLCTAQASRCRDCGNHITWHDR...TDH..RPIAMHP...Q.ELPATAVP.LVCRWHI...D.....SGIAHPAD....DGSP............WCRIPHTVLCPARSA..STLL...TPKLTALRRRLALHTRRLTD.............................................................
A0A3B0BWX0_9ACTN/2-97 ................gvnst-----------------PDAACPECGRIQKLRPK...TTG..GWIRLEP...E.TVPAAEAKdETLRWSI..tA.....DGYAVAGR....GTGG............KCYIEHRRVCSRRRH..HPEH...--------------------lgpifvarwlrnrs...............................................
A0A0B5DMJ4_9ACTN/1-112 .................mgal------EEKPRR--LGGQQPRCLYCGLPQDRVAT...LEY..DWVMLEP...DmAPPAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPAQSL..PD-L...WPWLTALRGENARQAER---de...........................................................
A0A3N5AF83_9ACTN/23-134 ....................r-PLRVTTTSPSRLLRASQTGRCRHCGSRIDLYQR...PDQ..RPIALHP...A.ELAVTDVP.ESCRWHL...S.....GGIAYPHG....DNSA............WCRIPHAVLCPHRTP..TCQP...SPRIEAIRRQLAVRARRLID.............................................................
A0A239HZR8_9ACTN/28-138 .....irlaaragipvadpag----------------GTATTCGRCACAAYRHRT...AGG..HWILVEP...G.EWPLGAVP.AGRRWRV..aG.....DGTAVNLR....ATVPs..........dTCRISHSDVCPAGPP..PA-A...SPVLLGQWRRNARR------rln..........................................................
A0A1Q4VS74_9ACTN/44-157 ....................h-EQAEAEGSDAP--APPAPPACRACGREQDRFPT...GYG..HWVLLEP...EvQPAALDVP.EGHRWVI..gH.....DGCAVNRV....GGSPp..........pCCRIAHRPVCARSPR..PAEL...PRIFLAVWELNAGYERRV--rg...........................................................
A0A6G3S0J8_9ACTN/1-86 ....................m--------------------------------PT...TDH..DWVMLEP...DmRPLAHLVP.AGHRWIE..vS.....DGRVALYEvcpvDGAQ............RCRIEHVLACPAQKL..GN-L...WPWLTTLRKENGRRAERQRD.............................................................
A0A117QM68_9ACTN/1-113 ...................mg----VLQEKPRR--LGGGQTRCPHCGLLQDRVAT...LEQ..DWVLLEP...DmHPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPAQPL..PD-L...WPWLTSLRGENARQAERR--dd...........................................................
A0A2Z5K134_9ACTN/38-154 .....................RAQAALEGATGP--EPPAPPVCPNCGLVGDRCVT...YYG..WHVLLEP...DlPVPAHMVP.AWHRWYV..dA.....NGTAWNSR....EDEPap........gaVCRVPHRIACPGLRL..EEIG..lWRWLDAVRAENARRAQRQ--sv...........................................................
A0A1V4AF95_9ACTN/36-123 ............asraaasps---------GTR-TADSSSTTCRMCGAPARWHRT...PRG..RWILMEP...G.DRPTGSVP.AGRRWRI..aG.....DGTAVYLA....SSLPs..........dTCRVSHFDFCPAR--..----...--------------------.............................................................
A0A4Q1RMC2_9ACTN/44-165 nqlaieegatarpqvapdpdd-------------VTPYEPPTCRDCGAAVRPYPT...NYE..RWVYLAG...E.DLPAKDVA.PCHRWRL...E.....--------....----............---------------..----...--------------------tirgrhssipaeivavrirgieplpsdpvrpahravclcpeavqeaeqeraae........
A0A550IC80_9ACTN/3-112 ...............adevpq-------------LGGKQRFTCLFCGLSQDRVPT...LEQ..DWVLLEP...GvDVLAHLVP.AEYRWIG..lS.....DGRVTVYA....VCPPds........sqRCRIEHRLACPGQQL..PD-L...WPWLTALRGENARRAEREA-n............................................................
A0A124HQM9_9ACTN/1-112 .....................--MQISPHSASRLLRCGQRDRCRACGNRIEWYTRgtdPHQ..RSVRLHP...G.EVPAARVP.AACRWHV...S.....SGVAYPAG....DGSR............WCRLPHAAVCPARD-..ADPA...CADLSGLRRALSVTTRRLID.............................................................
A0A1J4Q3C6_9ACTN/1-113 ...........mgasegrarr--------------LGGGRSRCPYCGLPQERVAT...LGH..EWVMLEP...DlRPPAHEVP.AGHRWIE..lS.....DGRVSVYG....VCPPdq........fqRCRIEHRLACPARLL..PD-L...WPWLTDLRGEKARQAER---pta..........................................................
A0A2T0R8A2_9ACTN/65-171 .........dhvrrmqrlaae--------------RPYVEEDCPHCGHLVHRYPG...PDG..GTVALAK...E.PVLAAGVP.DDARWRV...R.....DGRALPAP....DDDPdde......dsvGARVQHAVVCPANPA..--PA...NPRLSRLWH-----------ahle.........................................................
A0A7K2L3C6_9ACTN/23-127 ............rsggsapra--------------VGPAISACRRCGGRGVWYRT...AQG..RWIMIEP...G.ELASAAVP.AGSRWQL..aG.....DGTVVRSG....SAAPs..........dRCRVGHADVCAAGP-..EPVG...SPVLLALWRGHARR------ia...........................................................
A0A1H6C997_9ACTN/35-151 .............rpdpgpes-------------FEPIEPDECPKCGMEVRTVLT...NYE..RWVHLAT...R.SMRAKEVP.RRYWWRI...E.....--------....----............---------------..----...--------------------ptrpggttyvvgsiavrvggidplpddlvmpahtvvcadldaigevrrarladverqyrlp
D5ZQT4_STRV1/40-156 ....................q-AQAALDGATGP--EPPAPPLCPECGLAGERRPT...HTG..QHVLLEP...GyTLPAHLVP.GGDRWYL..gG.....DGTAWNGG....LDEPpp........gaTCRIPHRLACPGLTL..DEIR..pWRWLEAVREFNTDRARRKAD.............................................................
A0A2P8Q173_9ACTN/1-99 .....................-------------MRCGQPDRCRDCGNWIEWYHR...GNE..RPVRLHP...R.ELPAATVP.ESCRWHV...S.....SGVAYPAD....DGSA............WCRLPHAVVCPARDV..DSAT...VSRLAALRRSLAVNMRRLVD.............................................................
A0A6B3FYX5_9ACTN/3-89 ...............gsqepe----------------------------------...REG..PWLALMP...G.NYPARFFA.DDEVYHL...A.....GGIAWPGP....HHRDy..........gNAKVAHDACCPGRHP..NRPM..tSRGAAELWHAIRIRLARSQ-d............................................................
A0A124ICA9_9ACTN/23-133 .....................RSLRIAPDSASRLLRCGQTTSCRECGNPVECYLG...ADD..RLVRLHP...H.ELPVAGVP.ESCRWHV...S.....RGIAHPAG....DGSS............WCRLAHDLLCPARP-..APTA...APQLSGLRRTLALCTRRLLD.............................................................
A0A365ZKX2_9ACTN/28-95 ..........dgdaldgigpw-----------------GPPLCRRCDEPVRRLPT...TYE..RWVDLEF...D.ELPAKQVP.SRYRWRV...-.....--------....----............---------------..----...--------------------rpitpptsryvvgh...............................................
A0A429R2G5_9ACTN/6-116 ...........tiaartgrav-----------PDPRRPSTGTCDGCGAGAAWHRT...LRG..RWVLMEP...G.ELAARVVP.AGRRWRI..aG.....DGTAVALG....SAVPs..........dTCRISHFDVCPARPA..-PAD...SPTLLALWRGHARRRR----ar...........................................................
A0A3N6DMR1_9ACTN/20-135 ....................d-FQALLEGATAP--GPPEPPDCPFCDLPQDRYAT..gYAG..HWILLEP...RiLVPAHTVP.PRRRWVI..tS.....TRTALNLW....DAEPlp........gaMCRIPHRIACPYLAR..-EDH...WPWMTALREHNRRRMQRLF-e............................................................
A0A4R9ERR8_9ACTN/32-149 ....................r-AEAMLQGATAP--APPDPPVCPECGQEADRFPT...YSQ..AWVLLEPlepVnEVPAHFVP.PRQRWLV..nS.....DGVAWNPW....EAEPtp........gaVCRIAHRLVCPGVEP..LD-L...WPWLTAEREESGRRAQRLF-n............................................................
A0A1C4QJQ2_9ACTN/1-50 .....................----------------------------------...---..-------...-.--------.-------...-.....----MNLW....DAEPlp........gaQCRIAHRTVCPYLQP..DD-P...WPWTTALRQENERRALRLF-n............................................................
A0A1G9YQP9_9ACTN/67-183 .....................RAQAAMDGADAP--EPPSPPVCPQCGLAGDRHPT...YYG..AYVLLEP...GlTAPAHMAP.AWHRWYV..dS.....NGTAWNSG....PEEPaq........gaECRVPHRLACPGLTL..EEIG..lWRWLDTLRQENARCAQRQAD.............................................................
A0A2A2Z442_9ACTN/1-86 ....................m--------------------------------PT...LEH..DWVLLEP...DvNPPAHVVP.AEYRWIE..lS.....DGRVTVYA....VCPPdp........qqRCRIEHRLACAGQQL..PD-L...WPWLTAMREENARKAQRH--aa...........................................................
A0A239P0F4_9ACTN/26-136 .....................RALRIDADSPSRLLRSAQGGRCDFCGNRVEWYQR...PSS..TPVPLHP...E.ELPAGTVP.AGERWHV...S.....SGAAHAGH....DGSA............WCRVRHHAVCPAGPA..G-NR...SPLLAETRRALGLTSRRLQ-n............................................................
A0A0G3UPG2_9ACTN/21-130 ...........aealagigrp------------DARAGRPATCRACGDPAVWHRT...ADG..RWVLMQP...G.GVPYHLVP.AGQRWHI..aG.....DGTAANLA....HAAAd..........gTCRITHFAVCPLGAP..P--K...APHLLRLWRHGAARLGRL--t............................................................
A0A1E5P0D2_9ACTN/14-124 ....................k-AMRIHPHAPSKSLRSDNTGRCQYCHNLVWWFDR...ADG..GRIPLLP...K.QFPTSRVP.ARARWSV...D.....AGVAR-LG....SVED............TCWIPHPAICPGIEH..EEFT...DAGLADLHRQSAINMQTAI-r............................................................
A0A5N8XVZ8_9ACTN/1-87 ....................m---HVSPDGVSRLLRCGQGDRCRECGNRIEWYHR...GAE..RPVRLHP...H.ELPAARVP.TVCRWHV...S.....SGVAYPGG....DGSS............WCRLPHAVVCPARD-..----...--------------------tp...........................................................
L1KYN9_9ACTN/1-48 .....................----------------------------------...---..-------...-.--------.-------...-.....--MAHPAG....DGSS............WCRLPHALVCPARD-..TPPT...PPELAQLRRVLAVNSRRLID.............................................................
A0A345SWZ7_9ACTN/22-131 .....................RYLRIHQSSASKTLRSNDVDTCRYCGNLIEWFDR...WNA..ARIPLTP...M.EFPSRAVP.PRYAWNV...S.....NGVAH-GG....SGGE............FCRIPHPAICPALD-..HDDL...DPVLQPLVKALAVRMRTAI-a............................................................
A0A1V6MIR7_9ACTN/1-113 ..................mgv-----LDEKPRR--LGGGQNRCPHCGLLQDRVVT...LEQ..DWVLLEP...DmHPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACLQQAL..PD-L...WQWLTSLRGENARQVERRTD.............................................................
A0A3M0I920_9ACTN/57-159 ............apdpddvea-------------IGPPEPPTCPKCHHLVRRYPT...NYN..KWVDLAT...C.DLPAKDVP.EPYRWRL...T.....KGTGNRAG....TWIAvrvhvidprpsdLVTPAHAFLCPDEEA..E---...--------------------rqdldp.......................................................
A6WD97_KINRD/54-163 .......vlahvqrmarlvae--------------RPFTEEECAHCGHPVHRYPG...PGG..EPVRLAK...E.SVLAVSVP.AEERWRV...V.....DDRAVPAP....VLDEdde......dqvGARVRHDVVCPANPV..P--A...NPRLARMWQ-----------shlap........................................................
A0A6B2XCT6_9ACTN/23-134 ....................r-PLRMAATSPSRLLRTGHSGRCRWCGNRINWHQR...ADQ..RPIELHP...T.ELTAADVP.ASCRWHL...S.....SGIAHPHG....DGSA............WCRVPHSVLCPRHTP..TAPT...SPHIEAVRRQLAVHTRRLID.............................................................
A0A2W2K6W0_9ACTN/21-107 .............iegeepdk----------------------------------...-EV..AWIALMP...G.EYPARHFA.DREVYHL...A.....GGIAWPGP....HHRDy..........gTAKVAHDACCPGLHR..SQPT..tSPGAGELWRAMRLRLAR---sp...........................................................
A0A1X4ICH0_9ACTN/4-107 .................alvg-----------------GESRCPYCGLPQERVAT...IEH..DWVLLEP...DmHPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPEQPL..PD-L...WRWLTALRGENARQAVRR--nt...........................................................
D9WQY8_9ACTN/31-141 .....................RSLRIAPVSASRLLRCGQTTSCSQCGNPVEWYPG...ADD..RLVQLHP...H.ELRVARVP.ESCRWHV...S.....RGIAHPSG....DGSN............WCRLTHDVLCPARP-..APTT...APQLSGLRRSLALRTRRLLD.............................................................
V4IKP9_9ACTN/99-203 ..........lperskavpsp--------------GEGKPMTCRYCLAPGRWHTT...VGG..AWIPMEP...D.PFPAYRVP.ARHRWRI..aP.....DGTAVPLG....RAVPa..........dTCRVSHFSVCPARPA..P-VE...SPELMARWR-----------shggr........................................................
A0A2A4KGS1_9ACTN/23-136 .....................RSLRVDADSPTRLVRSAQPGRCPDCGNRVDWHPR...TDGddRAVGLHP...Q.ELPAAAVP.AASRWHV...S.....SGIAHPAH....DGTA............WCRIPHTALCPARSA..PAAL...TPQLAALRRHLALHTCRLI-n............................................................
G2NJN9_STREK/21-136 ...................af--HALLEGATAP--RPPSPPDCPFCELPQDRYPT..gYAG..HWVLLEP...RvRVPAHTVP.PRRRWII..tP.....DGVATNLW....DAEPlp........gtVCRIPHRAVCPRLLP..ED-H...WPWMTALRDHNDLRTRRLFD.............................................................
V6JV24_STRNV/32-137 ..............pedfewi-----------------EPPECPECHGEIRAFPT...NYD..RWVYLAP...H.EAPAKEIP.SRYRWRL..mEiprlySHVAVRMA....ATHPlp........geLVRPAHVAVCVSPD-..----...--------------------avaaveearesdlrrgqpr..........................................
A0A0M8YH73_9ACTN/1-109 ....................m---QICPDGVSRLLRCGQSGQCRDCGNRIEWYHR...STE..RAVRLHP...Q.ELPAARVP.AVCRWHV...S.....SGVAHPAG....DGSS............WCRLPHAVVCPARDI..-PPT...PPELAGLRRSLAVNTRRLID.............................................................
A0A445NJS0_STRNE/4-100 ................nhttp------------------DAACPDCGNVQDHRPL...RSG..GWIRLEP...EpQLPTAAVP.EQHRWFI..tA.....DGYAVDGH....GSDP............NCYIAHYRVCSRRPH..PEHM...HPVFTAIWLRN---------cardg........................................................
A0A100Y0W9_9ACTN/36-139 .....................RAQAVREGAVAA--PPPAPPVCDRCGARGDRRGT...YYE..AYVLLEP...EvRAPAEGVP.PWRRWYV..dA.....GGRAWNGG....SGPPrp........gtLCRIPHTLVCRAGG-..----...--------------------ppevagrpcgvag................................................
A0A1G5CV11_9ACTN/57-172 ...................al--QAALEGATAP--PPPAPPDCPHCALPQDRYPT..lHEG..HWVLLEP...RiVVPAHTAP.PRRRWII..tP.....DGNAMNLW....DAEPap........gaRCRIAHRMACPYVEP..ED-P...WPWTTMLRRENERRAQRLF-n............................................................
A0A7M3LZ68_9ACTN/43-151 ...................hd--RAIAEHADAP--APPAPPRCRDCARDQDRYET...RYE..HWVLLEP...RvLLPVPVVP.EGWRWIV..aG.....DGHAENRD....TPPSp.........etRCRIPHQLVCPVWPR..--PR...HPVLAAVWDLNRS-------hhp..........................................................
A0A101UAD6_9ACTN/21-131 .....................RSLRIEHDSPSRLLRCAQRDRCRECGNPVEWYHR...SFA..RPVRLHP...R.EVPAAEVP.TAYRWHV...S.....SGVAHPAG....DGRA............WCRLAHAPVCPARDA..A-PE...ASALDGLRRDLALHTRRLID.............................................................
A0A1Q5KS37_9ACTN/34-152 .....................RAQAARDGATGP--EPPDPPVCPAYGLAGERRPT...CTG..RHALLRP...ApPVPAHLVP.GVHRRHV..dG.....NGVAWNGG....PDEPpa........gtTCRIPHRLACPGLSP..SADEirpWSRLAETREHNALPARRKAD.............................................................
A0A1J4NQK6_9ACTN/1-112 ....................m---QVSVDGSSRPLRCAQRDRCSECGSLIEWYPCgagPHR..RPVRLHP...G.EVSAAHVP.GPCRWHV...S.....SSVAFPAG....GSSS............WCRLPHAVVRPSRAA..A-GA...PRALAGLRRSLAVRTRRLID.............................................................
A0A7Y0BAL7_9ACTN/1-111 ...................ma--MHLHRSNGTMLLRRDAVARCKHCGTPIEWFDR...YDG..QRIPLS-...M.EFPARPVP.VPMRWYT...A.....RGLAHPGA....DPNT...........gQCRIPHPAICPALEH..-TDL...PPEIEDLVGRLAVRMRKRID.............................................................
A0A505DEM1_9ACTN/1-86 ....................m--------------------------------PT...LEQ..DWVLLEP...GvDVLAHLVP.AEHRWIV..lS.....DGRVTVYG....VCPPdp........lqRCRIEHRLVCPRQGL..PD-L...WRWLTAMRVENARRSERQ--ag...........................................................
A0A561UFX3_9ACTN/61-167 .......rylarrsraladgy----------------ESVGRCRHCQREATWHLT...ARG..RWILLDP...D.NHPTADVP.HGRRWHL..dR.....FGTVVHPP....GTTP............HCRVVHWDVCPGLPA..--PR...DPYLALVRARL---------rgggrgq......................................................
A0A3N6FF72_9ACTN/21-136 ...................af--HALLEGAVAP--RPPAPPDCPYCDLPQDRRHT..gYPG..HWILLEP...RvLIPAHTVP.PRRRWII..tS.....DGIAMNLW....DAEPlt........gtLCRIPHSIVCPQLLP..QD-L...WPWVTALRHHNKQRRQRLFD.............................................................
A0A7L4YAN5_9ACTN/1-110 ....................m---VIAPDSPSRLLGAGQCSRCRECGNKIEWHNA...TGH..GYVSLHP...G.EVPSVLAP.ADHRWHL...A.....SGVAHPTD....GGGR............WCRLAHVVLCPARAE..PGTL...HSPLEDLRRCLALNTRRLTD.............................................................
A0A652L5I1_9ACTN/1-72 .................mrvl--------------------------------PT...NYD..RWIVLAT...V.ELPAKDVP.PRFRWRLvhgQ.....DGAVAVRV....RGIEpa.......lgdPVVPDHRMLCPAQEA..A---...--------------------app..........................................................
A0A3N5AQX2_9ACTN/3-113 .....................RSLQVTPGGASRLLRCGQNDRCHDCGNRIEWYHR...DTQ..RSVRLHP...H.ELPSARVP.AGCRWHV...S.....SGIAYPAG....DGSS............WCRLPHAVVCPTRDV..P-PA...PPELAELRRSLAVNTRRLID.............................................................
A0A1Q4YC39_9ACTN/17-132 ....................a-FQALLEGATAP--RPPAPPDCPFCDLRQDRYAT..hYEG..HWVLLEP...RvIVPAHTVP.PHRRWII..tS.....DGAAMNLW....DAEPlp........gtQCRIAHRVVCPYLKP..ED-P...WPWRAALRQENERRAQRLFD.............................................................
A0A371PQ97_STRIH/24-135 .....................RALRVATDSPSRLPCAAQSARCRDCGNRIDWYTR...TNQ..HPIGLHP...H.EMTAAAVP.ARCRWHV...S.....SGIAHPAH....DGTP............WCRVPHTTLCPALPA..TAPL...IPQLAELRRHLALRTRRLLD.............................................................
A0A0F5VU83_9ACTN/1-113 .........mgaldegprrle----------------RGRSRCLYCGLSADRVAT...LEY..DWVLLEP...DmEPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdp........fqRCRIEHRLACSAQPL..PD-L...WPWLTSLRGENGRRADRH--qt...........................................................
A0A0M9ZQ14_9ACTN/23-134 ....................r-PLRVTATSPSRLLRAGQHGRCRHCGNRIDLYPR...TDQ..RPIALHP...T.ELTAAHVP.ESCRWHL...S.....GGIAHPHG....DGSA............WCRIPHAVLCPRRTP..TCRP...SPCLEALRRQLAVRTRRLTD.............................................................
A0A0M8QSA1_9ACTN/1-113 ...................mg----VLEEEPRR--LGGGRFHCPYCGLPQERAAT...LEH..DWVLLEP...DmHPLAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPEQPL..PD-L...WRWLTTLREENARQAARQE-d............................................................
A0A1H5JW75_9ACTN/1-97 ....................m---------------------CPYCGLPQERVAT...IEH..DWVLLEP...DmAPLAHLVP.AEYRWIE..tS.....DGRVAVYG....VCPAep........fqRCRIEHRLACPEQSL..PD-L...WPWLTSLRGENARQAERLN-e............................................................
A0A6B3GSQ8_9ACTN/118-221 ..............peraeav---------PSP--GAGKPMTCRYCLAPGRWHTT...VGG..AWIPMEP...D.PFPAYRVP.ARHRWRI..aP.....DGTALPLG....RAVPa..........dTCRVSHFSVCPARPA..-PLE...SPELLARRRS----------hggr.........................................................
A0A250VR64_STROL/1-94 ....................m---------------------------EADRFPT...LSQ..AWVLLEPldpVnVLPAHFVP.PRQRWLI..nG.....DGVAWNPW....NAEPte........gaQCRISHTVACPGIEP..PD-L...WPWLTAMREENARRAQRLF-n............................................................
A0A177HLD5_9ACTN/23-134 ....................r-PLRVAATSPSRLLRAGQSSRCRRCGNRIDWYQR...ADQ..RPIALHP...T.ELPAVQVP.ASCRWHL...S.....CGIAHPHG....DGSA............WCRIPHTVLCPGRTP..TARI...SLCIEAARRQLAVHSRRLID.............................................................
V6JHC4_STRRC/33-149 .....................RAQAALDGATGP--EPPSPPHCPHCGLAGERRPT...YTG..QHVLLEP...AlVLPAHLVP.GGHRWHI..dS.....NGVAWNGG....FTEPla........gsRCRIPHQLACPGLSL..DEIR..pWRWLSAVREENARRAQRRAD.............................................................
A0A2M9IA11_9ACTN/23-133 .....................RSLQVTPGGVSRLLRCGQSDRCRECGNRIEWYHR...GTQ..RAVRLHP...R.ELPAARVP.AACRWHV...S.....SGVAYPAG....DGSS............WCRLPHAVVCPARK-..APAA...PTELAGLRRALAVNTRRLID.............................................................
L7F0J0_9ACTN/45-140 ..........dpepdpedmgw----------------AEPRICGRCHATVRCFPT...NYD..RWVELAT...F.ELPAKKVP.PQHRWRL...R.....RPTAANTP....IA--............---------------..----...--------------------vatvavrigaidptpgepvipahefvclre...............................
A0A1R1S4C7_9ACTN/25-136 .....................RFLRVAPDSPTRLLRAAQQGRCADCGNRIEWYER...TGG.rNPVPLHP...H.ELPAAAVP.TSQRWHI...N.....SGIAHPAG....DGSP............WCRVRHRALCPAHT-..AEPH...TGLLKALRRSLALHTRRLRD.............................................................
A0A2N5XHF7_9ACTN/27-136 ................aaaaa-----RTGTTVPDPRTPATTACDRCGADAGWHRT...VGG..RWMLLDP...G.TWPTGTVP.PGRRWRV..aG.....DGTAVNIG....GANPt..........dRCRISHFDVCPVNPP..PS-D...SPLLLGLWRRNAER------ac...........................................................
A0A0N0SMI0_9ACTN/23-133 .....................RSLRIAPDSASRLLRCGQTAYCRACGNPVEWYLR...GDD..RLVQLHP...L.ELPAALVP.ETCRWHV...S.....RGIAHPAG....DGSS............WCRLAHALLCPARP-..APSA...APQLSELRRSLALRTRRLLD.............................................................
A0A0B5EM15_STRA4/3-114 .....................RSLQLAATSPSRLLRAGQSSRCRRCGNRIDLYQR...ADL..RPIALHP...A.ELAVSQVP.EICRWHL...D.....QGIAHPHG....DGSA............WCRIPHAVLCPRRIP..TSRI...SPHLQAARRQLALHTRRLID.............................................................
A0A3R9YCB6_9ACTN/21-132 ....................r-PLRVATTSPSRLLRTGQSSRCRGCGNPIDFYQR...ADQ..RPIALHP...A.ELAAALVP.VSCRWHL...S.....CGIAHPHG....DGSA............WCCIPHAVLCPARIP..TLRL...TSHVEEMRRQLGVRSRRLID.............................................................
A0A7X0HGR8_9ACTN/28-125 .......lgtaarqlravpdp--------------RTSGGTSCKRCGASAEWHRT...VRG..KWILIEP...G.ERAVGSVP.AGKRWRI..aG.....DGTAVNLG....SAIPa..........dTCRISHFDLCPARSA..GA--...--------------------aaava........................................................
A0A6B3HIK9_9ACTN/118-221 ..............peraeav---------PSP--GAGKPMTCRYCLAPGRWHTT...VGG..AWIPMEP...D.PFPAYRVP.ARHRWRI..aP.....DGTALPLG....RAVPa..........dTCRVSHFSVCPARPA..-PLE...SPELLARRRS----------hggr.........................................................
A0A426UDS3_9ACTN/59-123 ...........dpgpddttwi-----------------EPPRCPECGAAVRIYPT...AYD..RWVSLAM...A.ELPAKDVP.EPFRWRL...-.....--------....----............---------------..----...--------------------trlpgrspvptd.................................................
Q9ADB8_STRCO/53-167 ..................hgm---GLLEREPRR--LSGGQSRCPDCGLLQDRVPT...LEQ..DWVLLEP...DmNPLAHTVP.AEHRWIE..lS.....DGRVTVYE....VCPPdq........sqRCRVEHRLACPARPL..PD-L...WPWLTSLRGENARRVERQND.............................................................
R6JST6_9CLOT/5-81 .................ydpf-------------------GTCRQCGDRILWVKT...KAG..KNMPVNP...E.LVNYKAVP.GGKERIV..tP.....EGVVVAGE....KCSVde.......aegCGYISHFATCS----..----...--------------------rr...........................................................
A0A3Q8V7V5_9ACTN/23-136 ....................r-PLRVAATSPSRLLRCGQSVRCRLCGNRIDVYLC...SDQ..RTIALHP...D.ELAAAQIP.ESCRWHL...S.....CGIAHPHA....DGSA............WCRIPHTVLCPGCSVpaTVQL...SPHVEAVRRQLAVRSRRLID.............................................................
A0A1B1M113_STRLN/30-141 ....................r-PLRVAATSPSRLLRAGQSGRCRHCGNRIDLYPR...ADG..RPIALHP...T.ELATAHTP.ASCHWHL...S.....SGIAHPHG....DGSA............WCRIPHAVLCPQRTP..ICRI...SPSLTSVRRRLAVRTRRLID.............................................................
R5ID68_9FIRM/1-83 ...................ms--------------------LCRGCGSQIEWIKT...TAG..RNMPVDP...E.PVFVIEGD.GRDRFVT...D.....DGAVIVGR....RARPeees....relpVAFVPHWKTCPNA--..----...--------------------gdfrrhg......................................................
A0A1A5P753_9ACTN/1-113 .........malseeklswld----------------GARSRCSYCGLPQERVAT...LEQ..EWVSLEP...DmRPPAHTVP.AEHRWIE..lS.....DGRVTVYG....VCPPdq........fqRCRIEHRLACPARPL..PD-L...WPWLTSLRGENVRQVDR---rdv..........................................................
A0A0F4JTI6_9ACTN/2-105 ...........sanserggrp-----------------EFGPCDGCGLMVEFREV..iDQQ..HDVALQP...G.EFPSQRLP.QRARWHL...A.....SGIAWPGE....NETA............WCRLDHDLICPAAE-..-EPE...ERVLRNLQSRLAVRARL---awd..........................................................
#=GC seq_cons ..............................s....hsspsspC.tCGt.h-ha.s...hpt..chVhLcP...s.clPAttVP.stpRWpl...u.....sGhAhshu....ssss............hCRlsHthlCPups...ss.h....shLpslRcp.uhpspR................................................................
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