#=GF ID DUF6097
#=GF AC PF19592.3
#=GF DE Family of unknown function (DUF6097)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 27.50 27.50;
#=GF TC 35.30 34.80;
#=GF NC 27.40 27.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 27694801
#=GF RT Polyketide and nonribosomal peptide retro-biosynthesis and
#=GF RT global gene cluster matching.
#=GF RA Dejong CA, Chen GM, Li H, Johnston CW, Edwards MR, Rees PN,
#=GF RA Skinnider MA, Webster AL, Magarvey NA;
#=GF RL Nat Chem Biol. 2016;12:1007-1014.
#=GF DR INTERPRO; IPR046079;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0001796) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, NRP (non-ribosomal
#=GF CC peptide). It includes a member from the tauramamide
#=GF CC biosynthetic gene cluster from Brevibacillus laterosporus DSM
#=GF CC 25 and appears to be predominantly found in bacteria [1].
#=GF SQ 23
#=GS W0PHF8_ADVMD/1-159 AC W0PHF8.1
#=GS A0A2D1SSE3_9BACL/1-139 AC A0A2D1SSE3.1
#=GS A0A0G4JPJ4_9GAMM/1-110 AC A0A0G4JPJ4.1
#=GS A0A241VWR8_9GAMM/1-151 AC A0A241VWR8.1
#=GS A0A844TV62_9BORD/1-158 AC A0A844TV62.1
#=GS A0A4Y4DRK1_GLUUR/4-143 AC A0A4Y4DRK1.1
#=GS A0A261UCC9_9BORD/37-195 AC A0A261UCC9.1
#=GS A0A1S8TKR8_9CLOT/1-139 AC A0A1S8TKR8.1
#=GS A0A5C0ZRZ9_9SPHI/6-163 AC A0A5C0ZRZ9.1
#=GS F0KGF1_ACICP/1-148 AC F0KGF1.1
#=GS A0A3N1IVZ9_9ENTR/1-145 AC A0A3N1IVZ9.1
#=GS A0A2U3MUX6_9GAMM/1-151 AC A0A2U3MUX6.1
#=GS A0A4Y6V2W6_SACBS/6-157 AC A0A4Y6V2W6.1
#=GS A0A2S0U8E5_9BACL/2-157 AC A0A2S0U8E5.1
#=GS J7U5R4_MORMO/1-152 AC J7U5R4.1
#=GS A0A2V1K0R5_9BURK/1-153 AC A0A2V1K0R5.1
#=GS E3E9M6_PAEPS/1-156 AC E3E9M6.1
#=GS A0A850EL01_9BACL/1-139 AC A0A850EL01.1
#=GS A0A212RLE3_9PROT/1-159 AC A0A212RLE3.1
#=GS M1LWY1_9CLOT/1-139 AC M1LWY1.1
#=GS A0A1B2M1N9_9GAMM/1-152 AC A0A1B2M1N9.1
#=GS A0A084A1J3_9GAMM/1-152 AC A0A084A1J3.1
#=GS S3N812_9GAMM/1-152 AC S3N812.1
W0PHF8_ADVMD/1-159 .............M.NLLHTFGASVQAMlfskQQLESMHRLIDSRNIPVEK.TEDFYQQAISLEQAAGY..SDFTRRYQRFSTAQKIMNGIAYVVTGFALLVFLLSKF------GPLKEPIHALFSLLMSDfMLFAVLMSViagiILLILIGLYFYTRTLYNkl....lgSELVKLWKRTIEHWSP.............
A0A2D1SSE3_9BACL/1-139 .............M.NVGRAVLRSLEFS....HELDLLHKHITHSQLPVRK.SDSFDNQCILLEQYLGE..DTFQSTYKKMKRVNILSGLFALPVLLIVAAAFVYGRWIDRDYD---------IFGFFVEH.-PVLYIVPA....VLIVVTLVLAAFHSLLR........---RKLYGRIYPELK-y............
A0A0G4JPJ4_9GAMM/1-110 ............m-.-------------....-------------------.----------IERYLGG..SKYANLNKKKRSANIIAGILALPLLIFSLFLFFSRYQKYFSFGFDMENTMETLFLMIIEY.PWAVILYAV....AFAAMVFYFYRLNSQSM........AEADKIIHAFMTQ---sps..........
A0A241VWR8_9GAMM/1-151 .............M.SNFQILSESLDNA....ELLKKLHHAIDEYRLPITS.KDDLNSQIVEIEKYLGG..NEFSNLNAKTKFANLGTGLLGLPVLIYCLFLFGSRYANSFGFNIDAAAFNHSLFMLVINY.LWILIIYAL....LFIGLVAYFYKLNKQVK........AKIYSIVNKLF-----tiln.........
A0A844TV62_9BORD/1-158 ..mkfsyrldasp-.----------QFVpfsrQQLLGMHALINGQKIGIEK.SQSLFQQIEALDSTIDD..HAYTQSLRRYRGERRLPLMMGLLFIVAVLSCGVATLT-AAEGG-----LTRILAALPFDA.RSLLHGLST....LTAGLFVAFALAHFYVRaraarltgKGLSRWWVAILQRWN-p............
A0A4Y4DRK1_GLUUR/4-143 ........mhhma-.---STTLGTLQLA....EELRKLHLAIPAKGLPVQL.RDDFYEQCIALEEHVGG..EGFRKTYKRSRMFNMLSGVVALPVLLAVIVLIILRYT-VSGFD---------PAAWVMDN.LWVVALSAA....LIIDVLVMSFMQKATLR........----------------llmnveypallgr
A0A261UCC9_9BORD/37-195 ............v-.NFLYNLGASLQFLsfakQQLQGMHALIHAKQIPVEK.SQDFFQQATDLERALGD..QSYAQSLRRYQNAKKCLVTVASLILAIAVILYALSLFGPTSGT--IKAAAGQLMSDFMLFaTTISIVAGV....LLVGLIGAHFYIRSLEKkl....igKNLSALWAKILQHWA-p............
A0A1S8TKR8_9CLOT/1-139 .............M.NFGRILHETLEFS....NELDILHKHITKNNLQVQK.SDSFDKQCFLLERSIGE..ERFKSTHKKMSIVNIMSGIIAFPVLLVILAAYIYAKWINKNFD---------VFRFILNN.-PEIYIIAA....VLLGITLILAMYHSILH........---KKLYYKIYPELK-r............
A0A5C0ZRZ9_9SPHI/6-163 .............M.GFLHSLGSSLQQVahlkEQLLYCHQWIDQHQIPVKKiEDNLDEQLVELEKWSHT..NSYSAVLKKGKLWKSITVSIALLIGLVIGGIYLTNLL------FPEYFIQKQVFSWMFSHiLPVTIILAI....VLLFLLVSVQIGNSYMRstr..gggKAYQQAWNEFRQHLK-n............
F0KGF1_ACICP/1-148 .............M.GNLTILGEALESA....EILKNIQYHIKDNRLPISL.KDDLNKQVIEVEKYFGE..DDFERLEVKKNKINIWTGVLAVPILIYCIALFLSRYVHNFGINIDVDVINHMLFDNIFKY.IWIVIIYAV....IFFGLIGYFYILNNHSK........KLIEKNVNKL------ls...........
A0A3N1IVZ9_9ENTR/1-145 .........mgif-.----------SNT....RQLKKLHQHIEAKCIPVTS.KDELVPQVQELERYLGR..TDFTALRGRKRIASILTAIVSLPVLGYGAIIGLDRYFAFEAGGFNARQVTLDIAQWLAGN.MQGLAVYGV....LFLVITFYYRWIDFCMG........RKVKNVIKQFMTQT--gg...........
A0A2U3MUX6_9GAMM/1-151 .............M.NNFQILSESLDNA....ELLKKLHHAIDEHHLPINS.KDDLNDQIIEIEKYLKE..NEFCNLLEKRKFVNLGTGVLALPVLIYCIFLFGSRYASNFGFNIDAAAVNHTLFIGIINY.LWIVIIYAL....LFVGLVVYFYKLNKQAN........EKIYSITNKLFDRL--n............
A0A4Y6V2W6_SACBS/6-157 qavlgpnesrrtg-.-------------....SHLSAAQRLIDYYLLPVEKeHWSFSKQMIHLERYAGGggGGFERASSRLRLADCALHGLSLTILLLLLGTAGLDLV------WPGLELREAVLSAVGANlEAVLLAVAA....LLMLVIALMGVRRSLGRe.....qeDHLVLLWQRVLE----vvnp.........
A0A2S0U8E5_9BACL/2-157 .............M.NFFSLLSRSMQNNlfiqTQLNSAHTLIEEYQLPVQKlEDDFYAQFILLENYAGV..NYFQRTLARYRRLNAWMLVLAVSILGAAAIIFGIEYT------MPEWKIADKLMDYLFEHfLPVIIGLTA....LFLLVIVLQFVRIHYANkl....msTAVNSSWRAILQKVE-s............
J7U5R4_MORMO/1-152 .............M.GIITAFAKSIDNS....QLLRLLHQQIEKQDAPVAC.RDDLDDQLTDIAAYMHD..EHYPALAKRRKKVNMLTGLLALPVLLFSLLLFSQKIIDALSLNIDISYLSLTLLDYSLTY.IWAVFIYAA....VLFGTIFYFYFLQKQTE........KYAGHLIDDFINRIS-h............
A0A2V1K0R5_9BURK/1-153 .............MlGNIKSLGTVLDNA....EVLKEVHRRIEQQRVPVAS.RDDIGPQLVELDRYMGT..AAFTGLHARANKANLWSGVVALPILFYGLLLAFDSIVRKLGVGVDSAALLQAVNLWLINN.LLLVGAWAI....LVAGVIFYFKWLNGKVE........EAKLALVDAFFEKTEP.............
E3E9M6_PAEPS/1-156 .............M.NVLGQLGSAIQSSlfiqSELKKAHALIQKHDLPVEQvEDDFHKQIILLEQYAGT..RIFQQGLARYKVINAMLLIISVIILLAAVIVATVEYL------QPERHLLQVLVNAMFDYwVPSITILSV....AFVGVIVLAIVRNVYARrl....htRVLDRSWQAIFQHVD-k............
A0A850EL01_9BACL/1-139 .............M.NMGKTLLSSMEFS....QELDMLHKHITNRELPVSK.SDSFDKQCMLLEESLGE..HAYQSTYKKMKKVNILSGLFALPVLLVVAAAFIYGRWIDRDYD---------VFGFFVDH.-PILYIVPA....ALIVVTLVLAAFHSALR........---RKLYGHIYLEL--ks...........
A0A212RLE3_9PROT/1-159 .............M.NFLYTFGSNVLFNnfamRQIEAFHAFIDSNKVPVNK.IDDLYKQTIALDRLAGT..GGFERCFRRYSITRKILIILAIVIIIPALSIFLISKI------QSLEAITNSLKEFMISNfMEVAYTLGIggalLLAFLIGGYFYAQSQLDrl....vgPELGQVWHSIIEKWA-p............
M1LWY1_9CLOT/1-139 .............M.GLGKILHEALEFS....NELDILHKHITKNNLQVQK.SDSFEKQCFLLERYMGE..EHFQSIHKKMNIVNIMSGVFAFPVLLIILMVYVYAKWIDKKFD---------VFGFFLNN.-PALYIVPA....VLIAVTIIFAIYHSILR........---NNLYYKIYPKLK-e............
A0A1B2M1N9_9GAMM/1-152 .............M.SILSTLSKTVDNA....QKLKELHQYIEQRDLPIQS.RDEYPAQIIEIEAYLGT..QQYRDFLKKKNTVNYLSGILALPALIFALFLFADRILSKWAIDLKVAEVSQKLLNFAIEN.SALMIIYAL....IFIATIIYFYALNRKTE........QYEEQVITAFLARTQ-r............
A0A084A1J3_9GAMM/1-152 .............M.GNINILMESTSNG....QLLKEIHYILEDNRLPIAS.KDELDSQVIELEKYLHG..SEYSAINAKKNKVNIWTGVLALPILISSILLYLTKYTNFFGVDLLSAIEPSLTFSNFMTY.LPVIIIYAL....IFFGLILYFYFLNKKEK........NMMMAVIDQFVNKINK.............
S3N812_9GAMM/1-152 .............M.NNLSLLSDALDDA....QYLKELHYFIEEHKLPITS.KDDLDEQIIVIEKYLGQ..DQFTQLHAKRKKANLGTGILALPVLFYCIFLFMSRYLGYFDVDLNVKSISQVIFADAIQY.IWFVALYAL....AFIGLVAYFYKLNTQAK........HTIRQVTQQLVQRTQP.............
#=GC seq_cons .............M.s.hphLtpulp.u....ppLctlHphIcpppLPVpp.cD-hspQhltLE+YhGs..spFpphhp+h+hsNhhoGllALPlLlhslhlahhphh..hshshs.t.h.p.lhshhhst.h.llhlhul....lhlullhhahhhpshh+........phhpplhpplhp+ht..............
//
