#=GF ID DUF6193
#=GF AC PF19692.3
#=GF DE Family of unknown function (DUF6193)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 26.90 26.90;
#=GF TC 27.50 27.10;
#=GF NC 26.10 26.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 19025863
#=GF RT Analysis of specific mutants in the lasalocid gene cluster:
#=GF RT evidence for enzymatic catalysis of a disfavoured polyether ring
#=GF RT closure.
#=GF RA Smith L, Hong H, Spencer JB, Leadlay PF;
#=GF RL Chembiochem. 2008;9:2967-2975.
#=GF DR INTERPRO; IPR045682;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0000087) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, polyketide. It includes a
#=GF CC member from the lasalocid biosynthetic gene cluster from
#=GF CC Streptomyces lasaliensis [1]. This family appears to be
#=GF CC predominantly found in Actinobacteria.
#=GF SQ 193
#=GS A0A0M9ZTX9_9ACTN/2-100 AC A0A0M9ZTX9.1
#=GS A0A3R8T3U2_9ACTN/13-126 AC A0A3R8T3U2.1
#=GS A0A5N8VYI2_9ACTN/142-237 AC A0A5N8VYI2.1
#=GS A0A4S2TE15_9ACTN/11-124 AC A0A4S2TE15.1
#=GS A0A101N1Q3_9ACTN/132-245 AC A0A101N1Q3.1
#=GS A0A5R9LLV4_9ACTN/133-246 AC A0A5R9LLV4.1
#=GS A0A6N2HR67_9ACTN/131-245 AC A0A6N2HR67.1
#=GS A0A5D0NGV4_9ACTN/118-220 AC A0A5D0NGV4.1
#=GS A0A498E4R4_9ACTN/1-88 AC A0A498E4R4.1
#=GS A0A372GL28_9ACTN/136-241 AC A0A372GL28.1
#=GS A0A3N6GFY5_9ACTN/8-113 AC A0A3N6GFY5.1
#=GS A0A5Q4TCW1_9ACTN/128-225 AC A0A5Q4TCW1.1
#=GS A0A2S1Z970_9ACTN/1-93 AC A0A2S1Z970.1
#=GS A0A8J3XP88_9ACTN/158-254 AC A0A8J3XP88.1
#=GS A0A318JTX8_9NOCA/105-211 AC A0A318JTX8.1
#=GS A0A5S9F4C1_9BACT/250-332 AC A0A5S9F4C1.1
#=GS E4N132_KITSK/123-233 AC E4N132.1
#=GS A0A1C6S983_9ACTN/12-117 AC A0A1C6S983.1
#=GS A0A1Q5MRG4_9ACTN/12-119 AC A0A1Q5MRG4.1
#=GS A0A0N0AUF5_9ACTN/133-246 AC A0A0N0AUF5.1
#=GS A0A1Q4WCZ0_9ACTN/1-90 AC A0A1Q4WCZ0.1
#=GS A0A2M9ICS9_9ACTN/1-88 AC A0A2M9ICS9.1
#=GS A0A1Q5DSS8_9ACTN/134-245 AC A0A1Q5DSS8.1
#=GS A0A4R2BLR2_9ACTN/15-127 AC A0A4R2BLR2.1
#=GS A0A8J4DNS6_9ACTN/100-197 AC A0A8J4DNS6.1
#=GS I2N2E8_STRT9/126-235 AC I2N2E8.1
#=GS A0A0N1GMX6_9ACTN/4-116 AC A0A0N1GMX6.1
#=GS A0A1Q5DC16_9ACTN/128-240 AC A0A1Q5DC16.1
#=GS A0A7W7HVL2_9ACTN/132-242 AC A0A7W7HVL2.1
#=GS A0A5D0PDS0_9ACTN/140-235 AC A0A5D0PDS0.1
#=GS A0A4R4P7B7_9ACTN/132-228 AC A0A4R4P7B7.1
#=GS A0A8J8BCS1_9ACTN/141-256 AC A0A8J8BCS1.1
#=GS A0A4R4T1Z3_9ACTN/138-235 AC A0A4R4T1Z3.1
#=GS A0A3E0HNS2_9PSEU/318-401 AC A0A3E0HNS2.1
#=GS A0A1G9TBU9_ALLAB/122-226 AC A0A1G9TBU9.1
#=GS A0A0D7CPR4_9ACTN/2-91 AC A0A0D7CPR4.1
#=GS A0A2D3UD87_STRC0/12-117 AC A0A2D3UD87.1
#=GS A0A5M3XFS2_9ACTN/131-238 AC A0A5M3XFS2.1
#=GS A0A2U9P9F0_STRAS/126-238 AC A0A2U9P9F0.1
#=GS A0A1H5W2R1_9ACTN/31-152 AC A0A1H5W2R1.1
#=GS A0A1H8AEP1_STRJI/158-269 AC A0A1H8AEP1.1
#=GS A0A0P4R5H1_9ACTN/110-231 AC A0A0P4R5H1.1
#=GS A0A7W5ANK5_9ACTN/129-233 AC A0A7W5ANK5.1
#=GS A0A2U2ZB50_9ACTN/1-94 AC A0A2U2ZB50.1
#=GS A0A6G4V4B3_9ACTN/8-126 AC A0A6G4V4B3.1
#=GS A0A5C5YUL1_9BACT/127-233 AC A0A5C5YUL1.1
#=GS A0A1H4QK29_9ACTN/11-132 AC A0A1H4QK29.1
#=GS A0A4S2SN60_9ACTN/130-238 AC A0A4S2SN60.1
#=GS A0A4V3J531_9ACTN/3-92 AC A0A4V3J531.1
#=GS A0A4R4P7V2_9ACTN/124-232 AC A0A4R4P7V2.1
#=GS A0A8J3WXI7_9ACTN/130-223 AC A0A8J3WXI7.1
#=GS D9W4W2_9ACTN/134-242 AC D9W4W2.1
#=GS A0A0P4RA13_9ACTN/9-114 AC A0A0P4RA13.1
#=GS A0A0M9VJ08_9FLAO/162-284 AC A0A0M9VJ08.1
#=GS A0A0J6XG35_9ACTN/2-96 AC A0A0J6XG35.1
#=GS A0A7H8K525_9ACTN/1-94 AC A0A7H8K525.1
#=GS A0A0G3UZK8_9ACTN/5-114 AC A0A0G3UZK8.1
#=GS A0A7Y5NWX3_9DELT/8-106 AC A0A7Y5NWX3.1
#=GS A0A2A3HPV3_9ACTN/5-100 AC A0A2A3HPV3.1
#=GS A0A1Q4Z0X8_9ACTN/133-246 AC A0A1Q4Z0X8.1
#=GS A0A4R4T3I9_9ACTN/2-91 AC A0A4R4T3I9.1
#=GS A0A0C2AXK4_9ACTN/1-112 AC A0A0C2AXK4.1
#=GS A0A6N2HG99_9ACTN/127-236 AC A0A6N2HG99.1
#=GS A0A542QIB7_9ACTN/17-120 AC A0A542QIB7.1
#=GS A0A1E5P0Y1_9ACTN/5-113 AC A0A1E5P0Y1.1
#=GS A0A1Q5E0V0_9ACTN/1-91 AC A0A1Q5E0V0.1
#=GS A0A344U5Q0_9ACTN/10-122 AC A0A344U5Q0.1
#=GS A0A066YGE9_9ACTN/128-238 AC A0A066YGE9.1
#=GS A0A848LZS9_9DELT/222-301 AC A0A848LZS9.1
#=GS A0A7K2FIP5_9ACTN/133-246 AC A0A7K2FIP5.1
#=GS A0A0K9XCF6_9ACTN/3-88 AC A0A0K9XCF6.1
#=GS A0A0N0SIC3_9ACTN/1-96 AC A0A0N0SIC3.1
#=GS A0A1H0BMF3_9ACTN/6-115 AC A0A1H0BMF3.1
#=GS A0A6G9YET8_9NOCA/140-251 AC A0A6G9YET8.1
#=GS A0A8J3TCM7_9ACTN/138-235 AC A0A8J3TCM7.1
#=GS A0A1S9P8B4_9SPHI/1-88 AC A0A1S9P8B4.1
#=GS A0A7W5ASC4_9ACTN/114-207 AC A0A7W5ASC4.1
#=GS A0A0E9MUH7_9BACT/137-224 AC A0A0E9MUH7.1
#=GS A0A8J3VD98_9ACTN/170-286 AC A0A8J3VD98.1
#=GS A0A1M7MJN4_9ACTN/125-231 AC A0A1M7MJN4.1
#=GS A0A7X0LT62_9ACTN/126-238 AC A0A7X0LT62.1
#=GS A0A2K8PAQ3_STRLA/141-244 AC A0A2K8PAQ3.1
#=GS A0A7K2KM35_9ACTN/132-243 AC A0A7K2KM35.1
#=GS A6C081_9PLAN/138-252 AC A6C081.1
#=GS A0A0M9ZIL9_9ACTN/133-243 AC A0A0M9ZIL9.1
#=GS A0A429S834_9ACTN/19-119 AC A0A429S834.1
#=GS A0A8J4E794_9ACTN/68-173 AC A0A8J4E794.1
#=GS A0A1T3NS86_9ACTN/131-242 AC A0A1T3NS86.1
#=GS A0A7Y0B5D3_9ACTN/1-96 AC A0A7Y0B5D3.1
#=GS A0A1X7HL29_9ACTN/30-78 AC A0A1X7HL29.1
#=GS A0A3A9Z1Y0_9ACTN/77-179 AC A0A3A9Z1Y0.1
#=GS B5H9Z4_STRE2/12-119 AC B5H9Z4.1
#=GS A0A101QNR6_9ACTN/130-241 AC A0A101QNR6.1
#=GS A0A0A8EXD6_9ACTN/12-117 AC A0A0A8EXD6.1
#=GS A0A561S9B5_9ACTN/35-152 AC A0A561S9B5.1
#=GS A0A0Q9AUG9_9ACTN/57-168 AC A0A0Q9AUG9.1
#=GS A0A368KNF3_9BACT/124-230 AC A0A368KNF3.1
#=GS A0A0F6YJR6_9DELT/228-339 AC A0A0F6YJR6.1
#=GS A0A101JL73_9ACTN/21-121 AC A0A101JL73.1
#=GS A0A8J3MJ46_9ACTN/133-239 AC A0A8J3MJ46.1
#=GS A0A1H8A1Y4_STRJI/11-121 AC A0A1H8A1Y4.1
#=GS A0A2L0NEM4_9ACTN/1-99 AC A0A2L0NEM4.1
#=GS A0A7Z0KVY6_9ACTN/133-246 AC A0A7Z0KVY6.1
#=GS A0A3D9SWD6_9ACTN/457-562 AC A0A3D9SWD6.1
#=GS A0A550HFA1_9ACTN/190-299 AC A0A550HFA1.1
#=GS A0A5Q4T7S9_9ACTN/126-237 AC A0A5Q4T7S9.1
#=GS A0A1Q4WNQ2_9ACTN/125-231 AC A0A1Q4WNQ2.1
#=GS A0A6G3S3L3_9ACTN/1-97 AC A0A6G3S3L3.1
#=GS A0A7Y6Q0T6_9DELT/9-107 AC A0A7Y6Q0T6.1
#=GS A0A1H7PCV1_STRJI/131-242 AC A0A1H7PCV1.1
#=GS A0A1G9JNL9_9ACTN/6-116 AC A0A1G9JNL9.1
#=GS A0A1B1AYM6_9ACTN/103-198 AC A0A1B1AYM6.1
#=GS A0A117IWH1_9ACTN/24-134 AC A0A117IWH1.1
#=GS A0A2G1X9Y6_STRCJ/12-124 AC A0A2G1X9Y6.1
#=GS A0A4Q9HUQ4_STRKA/1-105 AC A0A4Q9HUQ4.1
#=GS D9VLV2_9ACTN/43-162 AC D9VLV2.1
#=GS A0A1V9KJL7_9ACTN/140-251 AC A0A1V9KJL7.1
#=GS A0A7W9PQJ4_9ACTN/57-148 AC A0A7W9PQJ4.1
#=GS A0A2I0SH60_9ACTN/1-104 AC A0A2I0SH60.1
#=GS A0A1Z2KY42_9ACTN/12-119 AC A0A1Z2KY42.1
#=GS G8S6N8_ACTS5/126-208 AC G8S6N8.1
#=GS A0A810NVM4_9ACTN/57-160 AC A0A810NVM4.1
#=GS A0A4R5AGP9_9ACTN/113-222 AC A0A4R5AGP9.1
#=GS A0A2L0N8K6_9ACTN/111-220 AC A0A2L0N8K6.1
#=GS A0A495JDS7_9ACTN/128-252 AC A0A495JDS7.1
#=GS A0A239GEI2_9ACTN/133-244 AC A0A239GEI2.1
#=GS A0A124G8X4_9ACTN/93-206 AC A0A124G8X4.1
#=GS A0A285K8W5_9ACTN/5-96 AC A0A285K8W5.1
#=GS A0A7Y8X4D7_9ACTN/10-125 AC A0A7Y8X4D7.1
#=GS A0A7K2QAK3_9ACTN/10-121 AC A0A7K2QAK3.1
#=GS A0A2Z4UXA1_9ACTN/133-246 AC A0A2Z4UXA1.1
#=GS A0A7W8EIA6_9ACTN/3-114 AC A0A7W8EIA6.1
#=GS A0A2I0STI9_9ACTN/14-135 AC A0A2I0STI9.1
#=GS A0A426UFH6_9ACTN/3-61 AC A0A426UFH6.1
#=GS A0A066YLM1_9ACTN/133-246 AC A0A066YLM1.1
#=GS A0A2L0NBE0_9ACTN/57-168 AC A0A2L0NBE0.1
#=GS A0A5N8W1C1_9ACTN/1-91 AC A0A5N8W1C1.1
#=GS L1KKP7_9ACTN/132-248 AC L1KKP7.1
#=GS A0A7H1BID7_9ACTN/1-96 AC A0A7H1BID7.1
#=GS A0A8J4DE41_9ACTN/9-114 AC A0A8J4DE41.1
#=GS A0A1C4NCC7_9ACTN/142-257 AC A0A1C4NCC7.1
#=GS A0A0M9ZU55_9ACTN/1-87 AC A0A0M9ZU55.1
#=GS A0A8J4DGG2_9ACTN/16-106 AC A0A8J4DGG2.1
#=GS A0A0N0TU97_9ACTN/1-63 AC A0A0N0TU97.1
#=GS A0A250VIR1_STROL/135-239 AC A0A250VIR1.1
#=GS A0A0N0T4I8_9ACTN/132-243 AC A0A0N0T4I8.1
#=GS A0A239P7M0_9ACTN/131-229 AC A0A239P7M0.1
#=GS A0A2G1X9Z8_STRCJ/12-118 AC A0A2G1X9Z8.1
#=GS A0A561S9P3_9ACTN/131-240 AC A0A561S9P3.1
#=GS A0A101V3S6_9ACTN/126-237 AC A0A101V3S6.1
#=GS A0A7K2QPJ1_9ACTN/129-230 AC A0A7K2QPJ1.1
#=GS I2MYW4_STRT9/13-120 AC I2MYW4.1
#=GS A0A1H7G4M4_STRJI/3-98 AC A0A1H7G4M4.1
#=GS A0A327ZBD2_9ACTN/11-132 AC A0A327ZBD2.1
#=GS A0A0F2TGZ8_STRR3/131-239 AC A0A0F2TGZ8.1
#=GS A0A2R4FMJ2_9ACTN/133-237 AC A0A2R4FMJ2.1
#=GS A0A7W9UPR3_9ACTN/103-202 AC A0A7W9UPR3.1
#=GS A0A2D3UE37_STRC0/12-120 AC A0A2D3UE37.1
#=GS A0A372JRW8_9ACTN/1-96 AC A0A372JRW8.1
#=GS A0A7K0CPL8_9ACTN/28-149 AC A0A7K0CPL8.1
#=GS A0A1J4Q0E3_9ACTN/133-243 AC A0A1J4Q0E3.1
#=GS A0A177QNR0_9PLAN/137-192 AC A0A177QNR0.1
#=GS B5H9Z6_STRE2/11-118 AC B5H9Z6.2
#=GS A0A1C4VZA9_MICEC/6-113 AC A0A1C4VZA9.1
#=GS A0A1S2PN66_9ACTN/13-125 AC A0A1S2PN66.1
#=GS A0A250VE80_STROL/6-120 AC A0A250VE80.1
#=GS A0A2S4XSY7_9ACTN/131-226 AC A0A2S4XSY7.1
#=GS A0A810MWW3_9ACTN/113-213 AC A0A810MWW3.1
#=GS A0A2A4KDB0_9ACTN/5-115 AC A0A2A4KDB0.1
#=GS A0A117PTJ6_9ACTN/133-246 AC A0A117PTJ6.1
#=GS A0A2R4SYV2_9ACTN/133-244 AC A0A2R4SYV2.1
#=GS A0A8J4DVW3_9ACTN/132-233 AC A0A8J4DVW3.1
#=GS A0A066YHZ0_9ACTN/128-233 AC A0A066YHZ0.1
#=GS A0A8J7DYA5_9CYAN/34-147 AC A0A8J7DYA5.1
#=GS A0A2S9PSS0_9ACTN/10-121 AC A0A2S9PSS0.1
#=GS A0A3E0HNS2_9PSEU/120-217 AC A0A3E0HNS2.1
#=GS A0A0Q8PV76_9ACTN/133-246 AC A0A0Q8PV76.1
#=GS A0A5Q0LPR8_9ACTN/1-88 AC A0A5Q0LPR8.1
#=GS A0A841BH59_9ACTN/145-255 AC A0A841BH59.1
#=GS A0A239NV45_9ACTN/26-90 AC A0A239NV45.1
#=GS A0A2X0IJM6_9ACTN/1-95 AC A0A2X0IJM6.1
#=GS S4NUJ6_9ACTN/125-238 AC S4NUJ6.1
#=GS A0A250VFE0_STROL/133-246 AC A0A250VFE0.1
#=GS A0A0M8SLM4_9ACTN/1-89 AC A0A0M8SLM4.1
#=GS E4N2A6_KITSK/101-211 AC E4N2A6.1
#=GS A0A1I2E3H0_9ACTN/14-104 AC A0A1I2E3H0.1
#=GS A0A081C249_9BACT/124-209 AC A0A081C249.1
#=GS A0A2I0SN57_9ACTN/59-168 AC A0A2I0SN57.1
#=GS A0A429A4R3_9ACTN/131-242 AC A0A429A4R3.1
#=GS A0A7Y6Q0T6_9DELT/122-218 AC A0A7Y6Q0T6.1
#=GS A0A4Q6I6I9_9ACTN/14-65 AC A0A4Q6I6I9.1
#=GS A0A2A3HPC9_9ACTN/9-114 AC A0A2A3HPC9.1
#=GS W7STR1_9PSEU/112-216 AC W7STR1.1
A0A0M9ZTX9_9ACTN/2-100 ..........trgsfdd-----------...........--.------......--TLPPIAAAAYAEPVLRRLFPFHTHG..T.LKFIRD........A....PP..WHEp.pvDDLP.FI.V..L.................-.....G.D.PPYSVY...........TPAPTT.RL..GE.......AA..T..AEDAIGLVVAHLPPGLR------kdaag.....................................
A0A3R8T3U2_9ACTN/13-126 ...............dp--VAAKWQVVR...........DM.DANLID......----KALVEAAYANPALRALFPLVSHG..S.LQFSRC........T....RF..PWS....QDLP.SI.F..P.................Y.....D.GeRHFRVRrl......hepRGSGRE.QI..GG.......PV..T..ADEAVELVASHLPAGCGPALDGT..........................................
A0A5N8VYI2_9ACTN/142-237 ..............dpa---ATKWRQLL...........SS.DWHLRD......----RPLLEAAHAHPDLRVFYPDISMG..S.LMLSRQ........P....-F..DLE....SGLV.KI.T..P.................L.....S.E.DHYRVT...........-MWLAA.FR..RD.......VT..S..LNEALDVAAA-------------cfr.......................................
A0A4S2TE15_9ACTN/11-124 ................d-AVEARWQRMPmtw....rlvrDR.AESKTL......PQGVLSLLEAASAEPRLRRLYPFTKQW..T.LWFSPR........T....SP..PFN....VDVP.TA.E..P.................L.....P.D.GRFRVR...........GPRAGQ.VV..GE.......TD..T..AGAAIALVVAHLPAD--------grq.......................................
A0A101N1Q3_9ACTN/132-245 .................RVVSTAWRLTL...........ER.SRVIRL......--GDAELAEALYAQPTLRVFFPFPSHG..Q.FSLLSS........T....AD..PFH....EEVP.RV.R..P.................A.....R.D.NLWDVVtp.......psRQAQTH.VL..ET.......RL..T..AREAAALVAANVPAGSGPAIEG-g.........................................
A0A5R9LLV4_9ACTN/133-246 ................r-LTESEWQGIR...........QE.AAELEYa....wQETYHSLIEAAHTEPALRALYPFTSHW..A.LRFSTT........T....RP..DLT....VVGP.CL.S..A.................N.....S.D.GTHGVG...........RGLISQ.DL..GR.......FA..T..VREAVAVAVRQLPSGLGPTTLG-g.........................................
A0A6N2HR67_9ACTN/131-245 ................r-LTESEWRSMR...........QE.ADEMERg...awQEGYRTLVEVAYAEPALRALYPFTSHW..V.LRFSST........T....RP..HLT....IVGP.CL.T..A.................N.....G.D.GTYGVG...........RGFISQ.DL..GR.......FT..T..PHEAVALAVSRLPSALGPVALG-g.........................................
A0A5D0NGV4_9ACTN/118-220 ................d-LVALQWRELR...........ED.PDNDER......---IMPLLEAAHADPRLRALYPVVSHY..R.LLFSRR........A....AP..PYE....FLGL.KA.Y..R.................G.....R.D.GAHVVA...........G-QDDV.PL..KE.......TP..S..AEEAISFLASRIEE---------srsp......................................
A0A498E4R4_9ACTN/1-88 ..............mtl-----------...........--.------......---------VAHAEPRLRQLYPWTGMW..E.LHFSRC........T....EI..RHT....WDIP.YI.G..T.................L.....R.D.GRYYVE..........gPSRTSP.RI..AE.......TD..S..AQAAVAMVIDRLPPRCGPAFIG-n.........................................
A0A372GL28_9ACTN/136-241 ................d-LVAVHWREIL...........ED.AD----......FADIRPLLVEAHAVPRLRNLYPVVSHD..D.LFFSRC........T....AP..PYA....LIEP.HA.R..R.................-.....R.G.EKFVVL...........-GRGDD.LL..TE.......TS..S..AQSAISYLASILPAGIGPAVIG-d.........................................
A0A3N6GFY5_9ACTN/8-113 ................s-AVEAGWQTVR...........DD.GRVS--......----PELLEAAYAEPLLRPLFPWTGMG..E.LHFSRC........T....GG..RWT....WDIP.YV.L..P.................V.....V.G.GTYWVS...........GPLRTE.TV..GP.......AA..T..PQEAIAMVIERLPPGCDRAFVGT..........................................
A0A5Q4TCW1_9ACTN/128-225 ................d-VTRAQWDWLR...........TA.EVHADE......----RALVTAFHEDGRFHRFFPVLTHG..V.LRLGLD........G....GD..PEA....GAIA.VA.P..-.................-.....E.D.KAYRVT...........DTRSSG.PG..EV.......AA..S..PAEAVEAAARRLTD---------d.........................................
A0A2S1Z970_9ACTN/1-93 ................m-----------...........--.------......-----TLVRAAYAEPLLRQLYPWTSHW..R.LGFSRC........T....AF..PFT....MDIP.LV.Y..G.................C.....S.V.GGYRVEqp.......ksGPYDTE.WI..GD.......TS..T..AQEAVAMVVERLPPGCGPAFIGT..........................................
A0A8J3XP88_9ACTN/158-254 ...............dp--VGVQWSLLL...........GD.DGLA--......--EVMDLLRAVHSNDRLRKLMPYVSHG..T.LRLAND........P....WD..RTM....GEV-.WI.S..P.................L.....P.R.GTYRVL...........STDSSE.SR..KQ.......VG..S..LEEALETLVSYLP----------..........................................
A0A318JTX8_9NOCA/105-211 ...............dp--VETKWKLYL...........QT.QARHID......----HDLIEAAYAQPRLRMLFPFTSHE..S.LHLSRC........T....RF..PFT....HDLP.GI.F..P.................L.....S.D.GTYRVI...........-SPNRV.HI..GH.......TD..T..PQEAVSLLIDHLPSDCGPAIDA-t.........................................
A0A5S9F4C1_9BACT/250-332 ..............ysd----WHWQNVL...........QQ.ARSGDE.....vLEYYLPILEEIVVRPEIKCFFSFTSLN..R.LCFSRC........S....HY..PFM...tEGLP.VL.F..P.................T.....Q.E.GCFA--...........------.--..--.......--..-..-----------------------hcgeysic..................................
E4N132_KITSK/123-233 ................d-TVELAWCRLL...........DR.FHTPPMn....rFVRARALVAAAYARPVLRRLMPVTSHG..N.LWFSTS........T....TAnrRLT....GVGP.MI.W..P.................S.....Y.E.GSYAVR...........--DGHE.VL..AR.......FE..T..PEEAVAFVLAGLPEGIGPA----r.........................................
A0A1C6S983_9ACTN/12-117 ................a-VVEAGWQAVR...........DD.GRVRP-......-----DLVRAAYAEPRLRCLFPWTGMG..E.LHFSRC........T....EH..RWT....WDIP.FI.R..P.................A.....A.G.GTYAVE...........GPSRTQ.TV..GP.......AT..T..AREAVAMVVARLPAGCGRAFVG-n.........................................
A0A1Q5MRG4_9ACTN/12-119 .................EIVAKEWQTIL...........AY.GPERVD......----PAVPRAAYNHPALRELFPAVSHG..V.LYLSRC........T....RY..PWT....HDVG.TA.F..P.................Q.....T.S.GGYRVR...........RQSDNT.LL..GV.......TE..T..LDEAYQLIAATLPEGCGPAVDGT..........................................
A0A0N0AUF5_9ACTN/133-246 ................r-LAESEWQSLH...........VE.AREADYv....wQGTYQALIEAAHAEPALRALYPFTSHW..A.LRFSTT........T....RP..RLT....VVGP.CL.T..A.................G.....S.D.GTYGVG...........TGFITP.DL..GL.......FA..T..AHEAVAVATRHMPSGLGPVTLG-w.........................................
A0A1Q4WCZ0_9ACTN/1-90 ................m-----------...........--.------......-----RLLKAARAEPRLGRLFPWTSHH..D.LHFSLS........T....SA..PWT...aAGVP.FA.V..P.................L.....D.G.GGYQVR...........GQGGAG.VL..GT.......PA..T..PEEAVALLVEHLPPDLGPVFNH-p.........................................
A0A2M9ICS9_9ACTN/1-88 .................-----------...........--.------......------MVRMAHAEPQLRQLYPWTGMW..E.LHFSRC........T....GF..RPT....WDIP.YI.G..T.................L.....S.D.GRYYVE..........gPRRNSP.RI..AE.......TD..R..AQAAVAMVIERLPPGCGPAFVGT..........................................
A0A1Q5DSS8_9ACTN/134-245 ................r-LAESEWQGLR...........QQ.AAGLPCp....wAPAYRSLIEAAYAEPVLRALYPFTSHW..A.LRFSTT........T....RP..LLT....VVGP.SV.A..A.................N.....G.E.GAFAVS...........--GGPG.AA..GE.......FA..T..ARAAVAAALVRLPADPGPVALG-a.........................................
A0A4R2BLR2_9ACTN/15-127 .............eall----AEWTALR...........SL.WGGDDSw....vGDALRPVIESAFITPELRALFPFTSHN..S.LCFSRC........S....YY..PFT....LDSP.CI.A..A.................-.....W.P.DEYIVQa........lrAATDEP.PL..EP.......VH..TtdLDLAITTVIDNLPPN--------rat.......................................
A0A8J4DNS6_9ACTN/100-197 ................e-SVEAQWRALL...........DH.GDAYL-......----HPLAASAGARQTLRALRPRVSHG..T.LHLLHP........T....YR..TGGp..rRGLA.FH.P..L.................S.....G.D.GTYRVH...........LYDGPE.S-..-E.......WL..P..TDEAVTHAA--------------eaarh.....................................
I2N2E8_STRT9/126-235 ................g-AVELTWQAKL...........DR.IHMPPNd....rHLRPHALLAAAYARPVLRRLMPVNSHF..N.LWFSTR........V....EE..SWK...aRVGP.VV.C..P.................Y.....D.E.GFYGVQ...........--SKGE.RI..AR.......TE..T..PEEAVALLVAALPEGLGPA----s.........................................
A0A0N1GMX6_9ACTN/4-116 ................i-VVEAQWRKLL...........AT.ADGPDW.....lVEGFPRLVRAAYAEPRLRQLYPWTGMW..E.LHFSRC........T....QW..RHT....WDIP.YA.S..P.................R.....Q.G.GGYRVD...........GPGRSQ.HV..GE.......VD..T..ADEAMAMVVARLPPGCGPAFTG-n.........................................
A0A1Q5DC16_9ACTN/128-240 ................a-VVELQWRTMR...........EQ.AAEEPD......FTGFGELVEAAHAEPRLRQLYVFSSHW..T.LGFSSC........T....GY..PFR....DEVA.IV.P..S.................H.....R.G.RLFRVK..........rHPLSDD.VL..GE.......AA..T..AEEAVALAMRHLPADLGPAVAGT..........................................
A0A7W7HVL2_9ACTN/132-242 ................q-LVAAQWQWLR...........ED.AEQAN-......WPEHQALVEAAHAEPRLRQLYPYTSHW..S.LRFSTT........T....GF..PFS....PDAV.CL.E..A.................T.....L.N.GLFIAK...........TSFRGA.VL..GQ.......TG..T..AEEAVSIAVGHLAGDPGPATAG-s.........................................
A0A5D0PDS0_9ACTN/140-235 ...............tp--IEGQWERLF...........AD.PD-LI-......--GMRKLLRSAHERRELALLFPYVSHM..T.LRFIVD........P....YV..RSG....ATMS.-I.T..P.................I.....S.A.GSIRVE...........ILGMSD.TR..RE.......VP..S..VDDAVELAVA-------------ys........................................
A0A4R4P7B7_9ACTN/132-228 ...............dp--VAAQWEWLR...........EA.PEMAVD......----RDMVNPAYGNLVLRSCFPDLSHR..V.LSLSSS........F....-C..DRR....DEVR.IS.S..Q.................D.....D.A.RCFTVE...........-QAGRD.RR..IE.......CL..S..IAEAVIVAAE-------------fvss......................................
A0A8J8BCS1_9ACTN/141-256 .................EAVAVKWRRLL...........ER.LRQDVDrl..elARSVLALAETAFDEPKLRQLYPFTSHW..S.LHFTTC........T....GF..PFS....WDVP.FV.D..P.................L.....S.D.GRHVVS...........GPSRGT.VV..GE.......AD..T..PEDAVAMVVAGLPENCGPAVAGT..........................................
A0A4R4T1Z3_9ACTN/138-235 ................d-AVDFQWQALL...........ED.DDFL--......--EIRPLLFAVHTVEGLRSLFPLISHN..TqLRLHDD........V....NL..RNA....RQFW.VT.M..Q.................-.....S.G.GRYRVE...........LRGGLP.RA..EI.......VD..S..LAAAIDVLA--------------syvg......................................
A0A3E0HNS2_9PSEU/318-401 ................d-LLEYEWLQAR...........AH.ARYGV-......----RELVEAAMREPRLRRWYPVVGIN..A.LRFW--........A....DW..HVV....RKGP.IV.T..S.................V.....G.D.GRYKIH...........GEHGDE.L-..G-.......--..-..-----------------------qgdvdhv...................................
A0A1G9TBU9_ALLAB/122-226 ................n-AVEVKWRMLL...........ED.GDP---......--HLRPLIEAALTEPRLRELFPFTSRR..A.LLFSRC........T....GY..PYL....SVPP.VV.L..P.................L.....G.A.GRYRVV...........-GPDDT.VL..GE.......-D..D..AAGAVAVTVAALPADCGPAVPGT..........................................
A0A0D7CPR4_9ACTN/2-91 ...............gg-----------...........--.------......-----QLLRTAYAEPRLRQLFPWVGMA..E.LHFSRC........T....EP..RWT....WDIP.FI.A..P.................M.....M.G.GGFFVG...........GPSRSQ.SV..GP.......AP..T..AEAAIAMVVERLPPDCGRAFVGT..........................................
A0A2D3UD87_STRC0/12-117 .................RVVAAEWQQVL...........AY.GNDLVD......----PAVPRAAYAQPRLRELHPAVSHG..T.LFLSRC........T....KL..PGS....-FVP.VV.Y..R.................K.....V.E.GGYQVD...........-AHGIG.SL..GE.......VD..T..VEEAFALVVANLPEGCGPAVIGT..........................................
A0A5M3XFS2_9ACTN/131-238 ................d-VIAAQWQYTL...........KD.AQQSD-......WPEYQALIEAAYAEPKLCKLYPYTSHW..A.LSFSA-........T....PY..PFT....PSFV.SI.E..A.................S.....R.G.GGYTIR...........EWSNGP.AL..TR.......VP..T..PAEAISIAVNRLPADLGP-----ndr.......................................
A0A2U9P9F0_STRAS/126-238 ................a-VVDLQWRQLR...........EQ.AAGERG......FPEFALLVEAAYAEPRLRRLSAFSSHW..T.LGFSAG........T....GQ..SSG....VEVA.IA.P..A.................H.....D.G.RPYRVR..........aSLHDGD.LI..GE.......AD..T..ADEAVALAVAHLPVGLGPAVAG-a.........................................
A0A1H5W2R1_9ACTN/31-152 ................a-TVEARWQQLLlvwq...whhmRH.EILKPGt....aYPGIVSLIEAAGAEPRLRQFYPFTSHF..S.LNFSSF........T....SY..PWS....VQAP.SV.D..P.................L.....H.D.GRFRVR...........RPRSSE.VI..GF.......AH..T..ADAAVSLVVGNLPAGLGPAVAH-e.........................................
A0A1H8AEP1_STRJI/158-269 .................EVVELQWLMMR...........EQ.AAEAPD......FHEFAALVEAAHDDPRLRQLYVLSSHW..T.LGFSSC........T....GY..PFR....VEVA.IA.P..S.................H.....N.G.SPYRVQ...........EHLHSS.VI..GE.......AA..T..AAEAVALAAAHLPAGLGPAVAGT..........................................
A0A0P4R5H1_9ACTN/110-231 .................DVVEAHWQSLRlswq...wrhaVH.QIRSPGr....pYPGIVPLLEAAAAQPRLRRLYPFTSHF..A.LFFSSS........P....SY..PWT....VQAG.SI.V..P.................L.....H.N.GRFKVR...........RRSPRA.VI..GE.......VE..T..AEQAVALVLELLPTGPEPVIT--ts........................................
A0A7W5ANK5_9ACTN/129-233 ................e-AIAFRWGRYL...........DG.EEPVPH......GRELDGFLRAAAEEPRLRALYPFTSHW..D.FGLRPG........V....AD..TPN....RAVA.WI.R..P.................-.....V.G.DRYLVA...........GRDRGD.LD..RT.......ADpvG..ASDAVARILA-------------twdrg.....................................
A0A2U2ZB50_9ACTN/1-94 ...............me-----------...........--.------......--PFAELVRVAHAEPLLRQLYPWTGMW..E.LHFSRC........T....EI..RHT....WDIP.YI.G..T.................L.....R.D.GRYYVE..........gPSRSSP.RI..AE.......TG..S..ARTAVTMVIDRLPPHCGPAFIGT..........................................
A0A6G4V4B3_9ACTN/8-126 ...............rs--VREAWRDLLee......frpPH.SDSDPY......TPAMWALLQVAVRDPLLSTLYPGLSTT..M.LTLSRF........D....DY..RLRd..gECFP.VI.G..A.................-.....A.A.GEFGVSa.........yPVSEDN.LL..LV.......TS..D..PAQAVTLAARLIRDRL-------haiaas....................................
A0A5C5YUL1_9BACT/127-233 ...............ge--VDHRWNSYL...........SN.ADPYL-......-RELMPFIVLAAQQPSLRQLFPYTSHS..T.FCFSRC........T....GY..PFS....YDCP.HV.T..P.................-.....A.D.GLFTVG...........--RQAG.KI..LG.......AG..D..PEFAVSLVLDNLPVQCGPAIRGT..........................................
A0A1H4QK29_9ACTN/11-132 ................d-AVEARWQSLRlawq...wryaAH.QIRSPGh....pYPGIVPLLDAAAAQPRLRRLYPFTSHF..A.LLFSSS........T....VY..PWT....VQAG.TI.E..P.................L.....R.N.GRFKVH...........RRKPFA.VI..GE.......VR..T..AEEAVTLVLELLPTGTEPVITT-t.........................................
A0A4S2SN60_9ACTN/130-238 ..............tga---AYEWESVR...........RL.PDRLVD......----QTLVEAAFRSPQLSSLFPMVSHG..S.LQFRRL........T....VS..APG....SDVP.SV.F..P.................F.....G.E.GRWRVI..........cLWDRDI.PV..RT.......AD..T..VEEAVRLVVEGLPEGCGPALE--vi........................................
A0A4V3J531_9ACTN/3-92 ...........ppilaa-----------...........--.------......------LVDRAR-NSVLGRFYPFTSHT..A.LAFSTG........P....RH..WLGe..gEVLP.VA.I..A.................L.....ApE.GFYAVR...........--TRSG.TV..LE.......MV..S..ADEAVTE----------------aerlverlmdvhq.............................
A0A4R4P7V2_9ACTN/124-232 ................d-AVAVKWQLLD...........AD.-PGADY......---VRDVLNAAAARPELAQLFPWLSHHgtR.LHFSRC........T....GY..PFS....RDVP.YI.Q..G.................-.....N.L.ASYRVI...........DDRDGT.LL..GE.......YP..D..PVDAVAAVVNSLPEGVGPAVDG-d.........................................
A0A8J3WXI7_9ACTN/130-223 ...............dp--VETQWDLLL...........NE.DIYAS-......---LRPLLWAVRANQSLRRRFPYISHG..R.LRLARD........P....LV..RSL....DEV-.WV.T..P.................L.....S.S.GAYRIE...........TPRDPS.SA..AE.......YG..T..ISDAVNA----------------mdd.......................................
D9W4W2_9ACTN/134-242 ...............ag--VEFEWGVIR...........KL.SPELID......----QKMVEAAYVTPELRALFPMPAHG..S.LQFRRR........T....IS..APG....SDIP.SI.F..P.................A.....A.G.GCWTVI...........SLHDPQiPR..PT.......VS..S..AEEAVRLVVAGLPAGCGPAVE--vi........................................
A0A0P4RA13_9ACTN/9-114 ................d-IIEAAWQKLL...........TA.HRV--D......----GRLLRAAYAEPRLRQLFPWVGMG..E.LHFSRC........T....EL..RWT....WDVP.FI.A..P.................M.....M.G.GGFFVG...........GPSRSQ.SV..GP.......AP..T..AEAAIAMVVERLPPGCGRAFVGT..........................................
A0A0M9VJ08_9FLAO/162-284 ................r-EVAYAWNRML...........NT.RGEHL-......----KPIISLAMHDEVVGRLFPFTSHY..T.LCLSRC........T....GY..PYD...dIGLP.YV.T..PaqfarfedgrlimgeseG.....E.D.GRYIVS...........-RNRSE.YL..GE.......-G..N..AAEALALIKLHLPPHIQPAVAGT..........................................
A0A0J6XG35_9ACTN/2-96 ......herggspvlsr-----------...........--.------......--GVLALIEAASAEPSLRRLYPFTTRF..T.LWFSAR........T....SH..PFE....VVAP.AV.E..P.................L.....P.G.GRFQVL...........SPTRKL.VI..GE.......AD..T..ARAAVALVVAGL-----------aqap......................................
A0A7H8K525_9ACTN/1-94 ..............mkp-----------...........--.------......---FTELVRVAYAEPLLRQLYPWSGMW..E.LHFSRC........T....EH..RPT....WDIP.YI.G..T.................L.....G.S.GRYRVD..........gPNRNSP.RI..AE.......TD..S..AQAAVALVLERLPPDCGPAFIG-n.........................................
A0A0G3UZK8_9ACTN/5-114 ................t-VVEKTWRGIL...........ER.HPEARR......--GEPAVIAAAYAEPRLRALYPFPSHG..A.LSFHRN........T....HF..PWS....NDLP.YI.V..G.................-.....D.A.QSCIVY..........aPLRVGG.ML..GE.......SL..T..PQEAAALVVAHLPEGCGPAFEG-p.........................................
A0A7Y5NWX3_9DELT/8-106 ................a-IIDEKWVALL...........QR.AHGRV-......----RTIAQAAVLRPGLRALYPYQSMS..S.LGFSRT........T....TY..PYD....RMPY.VV.G..E.................G.....P.E.NGLYVA...........KEVNGS.VI..VE.......GDlaK..ALDAVESAIRRL-----------g.........................................
A0A2A3HPV3_9ACTN/5-100 ...........grtwvp-----------...........--.------......-PTLSAPVSAARASP-LARFHPFTGHA..R.LRFSTG........P....RF..RPGe..gTILP.VS.V..A.................L....gT.D.GRFLVRaq......eadGRQPPA.LV..LA.......AD..T..PAAAVAAVVRLL-----------eg........................................
A0A1Q4Z0X8_9ACTN/133-246 ................r-LTESEWQGLR...........QE.AAELEYv....wQETHQSLVEAAHAEPALRALYPFTSHW..A.LRFSTS........T....RP..DLT....VVGP.RL.G..A.................N.....A.D.GTYGVG...........SVMIGQ.DI..GQ.......FA..T..AQEAVAVAVRLLPSGLGPTTLG-g.........................................
A0A4R4T3I9_9ACTN/2-91 ..............dgr-----------...........--.------......------LSAAAYAEPRLRRLFPWTGMG..E.LHFSRC........T....EK..RWT....WDIP.YV.A..P.................A.....M.G.GGYRVS...........GPSRTQ.EV..GV.......AA..T..AEEAIAMVVERLPDGCGGAFPGT..........................................
A0A0C2AXK4_9ACTN/1-112 ................m--VSTAWRLTL...........ER.SPVIRL......--GDAELAEALYAQPALRVFFPFPSHG..G.FSLLSN........T....ED..PFR....EEVP.RV.T..P.................T.....V.D.GRWNVVl........tpLRIPER.VL..GS.......RL..T..AREAAALVAANIPAGAGPAVEG-g.........................................
A0A6N2HG99_9ACTN/127-236 ................g-VVELAWRVKL...........DR.IHMPPYd....rHPRPHAMLAAAYAQPVLRQLMPVNSHF..N.LWFSTR........V...eEF..RKT....RVGY.II.C..P.................Y.....D.E.GLYGVR...........--NEGE.LV..AR.......TK..T..PEEAVAFVVAALPEGFGPA----s.........................................
A0A542QIB7_9ACTN/17-120 ................d-ATEAGWQAVR...........RD.GRVRD-......-----ELINAAYGHPRLRQLFPWTGMG..E.LHFSRC........T....EH..RWT....WDIP.YI.Q..P.................A.....K.G.GGYWVS...........GPLRTE.SV..GP.......AA..T..AEDAIAMVIAS------------agqrrpgvcg................................
A0A1E5P0Y1_9ACTN/5-113 ................t-TVEKTWRLML...........EG.DPTVRR......--GDPAVMEAAYAEPRLRVLFPFPSHG..C.LTFHRN........S....QF..PWS....NDLP.FI.A..G.................-.....G.S.TACNVY...........GPLYSS.VL..GE.......GL..M..PQEAAALVVANLPDDCGPAFEG-p.........................................
A0A1Q5E0V0_9ACTN/1-91 ...............mr-----------...........--.------......----PELLEAAYAEPRLRQLFPWTGMG..E.LHFSRC........T....EG..RWT....WDIP.YI.Q..P.................G.....A.G.GRYWVS...........GPLRTE.VV..GP.......AE..T..VAQAIAMVLERLPAGCGPAFLGT..........................................
A0A344U5Q0_9ACTN/10-122 ...............ag--VEARWQRLPttw....rlmvER.GGSQAA.....aGRGVLALIEAAAAQPELRRLYPFTSHC..V.LRFGSR........G....GV..PTE....ADAP.AL.E..P.................T.....R.D.GRFRVL...........SPGLHR.VI..GE.......AD..S..AEEAVALAVAQLPP---------ps........................................
A0A066YGE9_9ACTN/128-238 ................g-AVELEWCRRL...........DR.VHRWPMn....gFPRVHALLTAAYAQPVLRQLMPVTSHF..N.LWFSTS........I....KP..NRRi..nGVGP.MI.W..P.................H.....Y.E.RSYAVL...........--DGHE.VL..AR.......FE..T..PEEAVTFVVAGLPEGIGPAT---..........................................
A0A848LZS9_9DELT/222-301 ..............rfa---EWRWEESL...........KQ.ARAAMEsrvsspLVPHLELLERLHALPSARRFYFFTSLW..T.LKFSRC........P....DY..SSS...tTGLP.FI.I..P.................-.....-.-.------...........------.--..--.......--..-..-----------------------hletgp....................................
A0A7K2FIP5_9ACTN/133-246 ................r-LTESEWQGMR...........RE.AAELEYa....wREAYRNLIEAAHAEPALRALYPFTSHW..A.LRFSTT........T....RP..RLT....VVGP.CL.S..A.................N.....S.D.GTYGVG...........HGFVSQ.DL..GQ.......FV..T..AREAVDVAVRRLPSGLGPTTLG-g.........................................
A0A0K9XCF6_9ACTN/3-88 ..............frd-----------...........--.------......--RLAELARVAYAEPRLRRLRPWTGMW..E.LHFSRC........T....EF..PPT....WDLP.YI.C..P.................G.....A.S.GGYWVE..........gPTRVCP.RI..AE.......TD..S..AQAAVAVVVERLPA---------..........................................
A0A0N0SIC3_9ACTN/1-96 ............mvldr-----------...........--.ADSKTM......GQGVLALIEAASKEPRLRRLYPFTSHW..T.LWFSSR........T....SP..PFN....VGVP.AV.E..P.................L.....A.D.GRFRVR...........GPRMTN.VI..GE.......TD..T..AEAAIALVVAQLPPD--------..........................................
A0A1H0BMF3_9ACTN/6-115 ................d--IETAWLQLL...........EG.TPGTRQ......--GDPLVVEAAYAQSRLRALFPFPTHG..T.LHFLCA........A....PP..PWPgsdrDRLP.FI.V..C.................-.....G.E.QPYKIY...........TPDYGE.LL..GE.......AA..T..PEEAAALLVAHLPDAVG------edad......................................
A0A6G9YET8_9NOCA/140-251 ...............dp--VAVTWKSYR...........RT.RASHID......----HDLIEAAYAQPRLRVLFPFTSHE..S.LRLSRC........T....RF..PYS....RDLP.VI.W..P.................L.....K.D.GRYRVVrq.......giPHREPV.EL..GL.......VD..T..PDEAVALLVAHLPDNCGPAIDGT..........................................
A0A8J3TCM7_9ACTN/138-235 ...............dp--VTTQWQRLL...........ED.GDLE--......--SIRPLLRAAYANSRIRSLFPVVSHT..T.LLRLAR........N....PV..DRS....GDET.WI.T..Q.................T.....S.D.DAYRVE...........LTRRDR.PQ..RV.......AG..S..PGEAIEVALSYL-----------d.........................................
A0A1S9P8B4_9SPHI/1-88 ...............ms-----------...........--.------......-----TVVRLAKQDEVLGALFPFTSMN..R.LCFSRC........T....GY..PYT....SDIP.LI.Q..A.................A.....L.D.GTYQVR...........-LPDNT.LL..G-.......GG..N..AIEVISLLKQNLPANIQPAVPGT..........................................
A0A7W5ASC4_9ACTN/114-207 ................g---ETRWLWLY...........EN.HCADSV......ADRLAPFVELAFDVPELRALEPSTSHF..S.LHVGRN........-....--..---....--GP.VV.E..P.................V....gT.S.GRFRVH...........--TRDG.RT..HD.......ET..D..AAGALRIVLASLPD---------lt........................................
A0A0E9MUH7_9BACT/137-224 ...............ke--IEFTWELLK...........ND.DDSLG-......---LKEFIGVASQDNTLNKLFPFTSLY..T.MCFSRC........T....GF..PYD...tNNLP.NV.T..L.................L.....E.Y.AHFI--...........------.--..--.......--..-..-----------------------lpkneaeyskiqhtkat.........................
A0A8J3VD98_9ACTN/170-286 ................h-VIASQWGYLR...........QE.ARAAN-......WPTQVELIEAAYARPELRRLYAFTSHW..T.LRFATVlpperpevS....DG..EVS....LNTV.CI.A..A.................S.....G.E.DGFTVRarwt..elkdgEHTPGA.II..AN.......TN..T..ADEAVYLALR-------------sa........................................
A0A1M7MJN4_9ACTN/125-231 ................h-AVAEKWCRYL...........EP.DRYED-......----LELIRAAYDEPRLRALFPFTSHG..S.LLFSRC........T....GW..PFS....RDVS.AI.Y..P.................L.....G.G.GRYAVR...........HRGEDF.SV..EP.......SY..T..AKEAAAAVVARMPASWGQAIAGT..........................................
A0A7X0LT62_9ACTN/126-238 ................a-VVELQWRTMR...........EQ.AAEEPD......FTGFGELVEAAHAEPRLRQLYVFSSHW..T.LGFSSC........T....GY..PFR....VEVA.IV.P..S.................H.....S.G.SPFRVK..........rHPLSDD.VL..GK.......AA..T..AEEAVALAMRHLPTDLGPAVAGT..........................................
A0A2K8PAQ3_STRLA/141-244 ................d-AVAVRWARLR...........DS.VAWGPD......-GELQALVEAAFAEPRLRALSPGTSLS..W.LRFGRG........P....VP..PPR....HDLP.MA.M..P.................A.....G.D.GRYRVR...........--TPDG.RV..RE.......AA..G..TAGAVALLLSLLPDGT-------aa........................................
A0A7K2KM35_9ACTN/132-243 ................a-VVDVQWRLMR...........EQ.AATATE......SREFGLLVEAAHAQPRLRQLYPFSSHW..T.LGFAAR........T....GT..PSP....PVVA.IS.P..A.................Y.....G.D.RPYRVR...........EYPQGD.CL..AE.......AA..T..AQEAVALAVARLPAGLGAAVAG-a.........................................
A6C081_9PLAN/138-252 ................k-VVNAQWDKYH...........DH.LADGHL......--DLFDFYQVAKVTPELRQLFPFTSMW..F.FCFSRC........T....HY..PFT....RDCP.HV.R..P.................K.....Q.SfINHEVIpg......yyeVFLRER.YL..GE.......-G..P..AERAAQIVVQYLPRNCGPAQ---lct.......................................
A0A0M9ZIL9_9ACTN/133-243 ................r-LTESEWQHLL...........TE.AGEVD-......WPEYRALIEAAYAEPALRRLYPFTSHW..V.LRFSTS........T....RP..RLT....VVRL.CL.A..A.................H.....R.Q.KPFTVS...........TNMTGE.GL..TE.......AT..T..AAEAVSIAASRLPTDLGPVTLG-a.........................................
A0A429S834_9ACTN/19-119 .................EVVAATWRYFL...........EE.GGELVD......----PAVVRAAYAQPRLRELCPGVSHG..V.MFFNRG........T....GF..AAR....RVGG.EV.H..K.................T.....P.D.GRYRVR..........gPLEAPT.TL..AE.......VD..T..LDEAFALLVTTLPA---------p.........................................
A0A8J4E794_9ACTN/68-173 ................e-AIDYRWRQYH...........AN.SSGAVQ......LTRLHPFISHAFGEPRLRALLPYTSHW..T.LHFSWT........V....SP..PYS....DDCP.VV.V..P.................L.....S.D.GRFLVT...........TA-DGR.EL..GM.......AD..-..PAGGVALVLTAL-----------gevpaaq...................................
A0A1T3NS86_9ACTN/131-242 ................d-AVEAKWTSYR...........RT.TARHVD......----HELIEAAYAQPQLRALFPFHSHR..T.LNFSRC........T....GF..PYT....HDIP.VI.T..P.................-.....A.N.GSYRVTww......htrSPHGPA.GI..GD.......AD..T..PDDAVALVVAHLPHNCGPAVVGT..........................................
A0A7Y0B5D3_9ACTN/1-96 ...............ms-----------...........--.------......----AELVAAAYAEPRLRQLFPWVGMW..E.LHFSRC........T....EQ..RWT....WDVP.YV.G..P.................TaagpgH.A.GPYYVE...........GPLRTQ.KV..GR.......AD..T..AQEAIAMVVERLPPNCGPAFDGT..........................................
A0A1X7HL29_9ACTN/30-78 ................a-LVEAGWQKVR...........DD.GRVR--......----PELLEAAYAEPRLRQLFPWTGMG..E.LHFSRC........T....--..---....----.--.-..-.................-.....-.-.------...........------.--..--.......--..-..-----------------------y.........................................
A0A3A9Z1Y0_9ACTN/77-179 ................e-AAECTWRRYH...........EN.ARRAPQ......LLRLHSFITVAIHEPRLRQLMPFTSHW..N.LGFSRT........V....GY..PYS....GDCP.WV.E..P.................L.....D.G.DRYRVT...........AADRRR.EL..GT.......AD..A..A-RSVALVLAELPD---------r.........................................
B5H9Z4_STRE2/12-119 .................RVVSAQWQQVL...........AY.DSYTVD......----PAMPRAAFAHPRLRELYPVVSHG..A.LYLNRC........T....GF..PTP....GDVG.AL.F..R.................R.....A.G.GGFIVI...........RHSDGA.VL..GE.......PD..T..VEEAVELIVRNLPDGCGPAVIGT..........................................
A0A101QNR6_9ACTN/130-241 ................a-VVALQWRSLR...........RR.AAGAPD......VPEFGDLVEAAHAEPRLRQLYVFSSHW..T.LGFSSC........T....GY..PFR....TEVA.IA.P..A.................L.....G.V.SPYRVM...........RRPYRT.AI..GE.......AA..T..AGEAVAFAVSRLPADLGPAVAGT..........................................
A0A0A8EXD6_9ACTN/12-117 ................d-IIEAAWQKLL...........TG.HRV--D......----GRLLRAAYAEPRLRQLFPWVGMG..E.LHFSRC........T....EL..RWT....WDVP.FI.A..P.................M.....M.G.GGFFVS...........GPSRSQ.SV..GP.......AP..T..AEAAIAMVVERLPPGCGRAFVGT..........................................
A0A561S9B5_9ACTN/35-152 .......havdaawqal---HLRWQWHH...........ET.HRARP-......FPALLPLWEAAAAQPRLRRLYPFTSHY..T.LRFSST........T....TF..PWT....PQAG.LI.E..P.................L.....H.N.GRFTVR...........SCHPSA.VV..GE.......VG..N..AEDAVALLLDLLPADSDPVVT--sg........................................
A0A0Q9AUG9_9ACTN/57-168 ................t-AVETMWTIYR...........QT.TATHVD......----HDLIEAAYAEPQLRALFPFHSHR..S.LNFSRC........T....GF..PYT....HDVP.VI.T..P.................-.....V.D.GKYRVTww......ktrSPHGPA.DI..GE.......TE..N..PHDAVALVLVHLPAGCGPAAAGT..........................................
A0A368KNF3_9BACT/124-230 ...............ne--VNFAWERYL...........SD.DDDLP-......--ELRELFRLAAAVPKLRQLFPFTSLH..R.LCFSRC........T....GY..PYV....CDLP.YL.C..P.................C.....E.D.GTYEAR...........--DAKN.RL..LY.......KG..T..AAEAVQAATAILPADCGPARPGT..........................................
A0A0F6YJR6_9DELT/228-339 .............parw-----HWLHVR...........DR.IANPHD.....vLAPLRELLAALAQSPIATRFYSYSSLS..Q.LCFSAS........S....HH..PWV...dADLP.VI.A..P.................G.....R.D.GTYLVH...........DRDGEP.ER..CG.......LR..R..AVERVEATL--------------arskvppffgsap.............................
A0A101JL73_9ACTN/21-121 ..............drr---ETMWLHLS...........EN.HYADPV......LARLHAFSTLASREPRLRALHPRLSVL..T.LSFRPT........A....DR..RNG....PRLP.AV.I..P.................T....pT.P.DRFTVR...........---TST.HI..HD.......EC..T..APTALHLVLTDLP----------t.........................................
A0A8J3MJ46_9ACTN/133-239 .................DVVEAAWLSLH...........DN.HMDDVV......RARLHPFLALAFQEPRLRRLRPFTSHW..T.LCFSRT........V....TY..PWS....RDCP.SV.D..P.................L....lE.P.GTYRVL...........-AADGR.EL..GV.......-A..D..AAGCLALVLAELDA---------taagp.....................................
A0A1H8A1Y4_STRJI/11-121 ..............drd------WREVLdaw.....rppHQ.AGDWA-......SPAMWDLLQLAADEPALRRLFPWTSMN..E.LHVSET........G....DF..RDYa..gEPFP.AI.A..A.................-.....S.T.SGFVVM...........AHPWGP.DH..VV.......LE..T..ADPAATLA---------------cmvrlmenqep...............................
A0A2L0NEM4_9ACTN/1-99 ............mredi-----------...........--.-----P......FPTVRDLVEAAHAEPKLRQLYPFTSHW..S.LHFTTC........T....GY..PFT....WVVP.FV.D..P.................L.....R.D.GRYRVC...........GPDRGT.VI..GE.......AD..T..AEQAIALVISHLPTSIGPAVAGT..........................................
A0A7Z0KVY6_9ACTN/133-246 .................RLVESEWQSMR...........VE.ASGLDYv....wQKTYQALIEAAHAEPALRALYPFTSHW..A.LRFSTT........T....RP..RLT....VVGP.CL.T..A.................G.....S.D.GMYGVG...........TGFITS.DL..GL.......FA..T..AHEAVAVAVHHMPSGLGPVT---lag.......................................
A0A3D9SWD6_9ACTN/457-562 ................d-LVEAGWREVR...........ED.GRVRE-......-----ELIDAAYAEPRLRQLFPWTGMG..E.LHFSRC........T....GK..RWT....WDIP.YI.Q..P.................T.....A.N.GGYWIS...........GPLRIQ.SV..GP.......AW..T..ADEAISMILEHLPPGCGPAFVGT..........................................
A0A550HFA1_9ACTN/190-299 .................EAVAFKWQLVR...........NA.PDQLID......----HDIVEAAYANPVLRSLFPLISHG..S.LQFSRC........T....RS..PWS....YDVP.SL.S..P.................Q.....L.G.GGWRAL...........RAHKGR.DIpdRH.......AQ..T..PEEAVAFVVEGLPDGCGPAVEG-p.........................................
A0A5Q4T7S9_9ACTN/126-237 ................a-VVDLQWRLLR...........ER.AAGETG......FPAFGLLVEAAYAQPVLRRLSVFSSHW..V.LGFSAG........T....GP..SSG....AEVA.VA.P..A.................Y.....G.G.RPYEVR...........RFLHEG.VI..GE.......AG..T..AEEAVALAIARLPADLGPARA--ap........................................
A0A1Q4WNQ2_9ACTN/125-231 ................d-AVPVRWRRLR...........ES.ATYERR.....hETGLRELVEAAHAQPRLRALSPGRSMY..W.LTFSRR........A....AP..PIS....YDLP.RV.A..P.................L.....G.D.GRYRVR...........--FDDG.RL..QD.......VD..G..AEAAVAAVVDALPDDAVP-----s.........................................
A0A6G3S3L3_9ACTN/1-97 .........mrddgrvr-----------...........--.------......----AELLEAAYAEPHLRQLFPWTGMS..E.LHFSRC........T....AF..PWT....WDVP.YI.Q..P.................A.....A.E.GTYWVS...........GPLRTE.TV..GP.......AA..T..VQEAIAMVVKHLPARCGPVFIGT..........................................
A0A7Y6Q0T6_9DELT/9-107 ...............pf---ERQWRWLL...........EY.GNARE-......----KALVHRLYVEPRVRFYCPYPTSN..E.IHLSRN........T....AY..PWD...dNGMP.FV.V..A.................E.....S.D.GTYSVR...........NGDG-G.VH..V-.......RV..T..ID---------------------evaagllalleqlep...........................
A0A1H7PCV1_STRJI/131-242 ................d-VIASEWQWLL...........KD.ADHAE-......WPQYWDLIEAAHAERQLRRLYPFTSHW..A.LSFSNT........P....DF..PFS...pSFVS.ID.S..P.................R.....G.A.GDYIIR...........EWWNGP.AL..HQ.......VT..T..AAEAIAIAVGRVPADLLHASS--rh........................................
A0A1G9JNL9_9ACTN/6-116 ................d--IETAWIWLL...........ER.RREMRGa....fDDALPPIAKAAYEQPALRRLFPFHTHG..T.LKFTRT........AppwgDP..PPR....NNSP.FI.V..T.................-.....G.G.PPYSVY...........RDGYRT.LL..GE.......TS..T..AEDAVQVVVDHLPADL-------rr........................................
A0A1B1AYM6_9ACTN/103-198 ...............dp--VATKWRQLL...........SS.DWHLRD......----RPLHEAAHVHPDLRVFYPDISMG..S.LMLSRK........P....-F..DLE....SGLV.KI.M..P.................L.....S.E.EHYRVT...........-MWPTA.FR..RD.......VT..S..LNEALDVAVA-------------cfr.......................................
A0A117IWH1_9ACTN/24-134 .................HVVDLQWRRLR...........EQ.AVEAD-......YSDFLVLLDAAASEPRLRQLFPFTSMW..V.LCFSSN........I....EK..PSL....AEAP.AV.V..A.................Q.....L.D.GRFEVK...........TDRWGD.II..GE.......TD..S..AHEAIALVVANLPERLGPAGR--hi........................................
A0A2G1X9Y6_STRCJ/12-124 .................EIVAAAWQRVL...........AM.DENLVD......----PKKTRLTYSYPELRVLYPLVSHG..M.LQLSRC........T....DF..PWT....ADVP.VI.Y..R.................R.....V.E.GGYVVRrl......drpNGADDA.IV..GY.......TD..T..LEDAVALVAANLPPGCGPAIQGT..........................................
A0A4Q9HUQ4_STRKA/1-105 .................-MVQAGWQAVR...........QD.GRVRDG......------LIDVAYQEPRLRQLFPWTGMG..E.LHFSRC........T....EY..RWT....WDIP.YI.Q..P.................A.....K.G.GGYWVS...........GPLRNE.AV..GP.......AA..T..AEEAVAMVVARLPSGTGPAYVGT..........................................
D9VLV2_9ACTN/43-162 ................a-AVEAKWEHMArswkwsaeyavLQ.SPSRV-......YPRIVELVAAARAVPELRRLYPFTSHM..I.LKFSST........T....TI..PYE....VRLP.SV.E..P.................T.....A.G.GRFRVR...........--RGGE.VL..GE.......FD..S..TGEALALVLAHAPPGLGPAVPG-e.........................................
A0A1V9KJL7_9ACTN/140-251 ................a-AVTAQWDLLR...........EK.ATSVPR......FPEFGSLIEAAHAEPRLRRLFPFTSHW..T.VASSSC........T....GR..PYR....DEIA.IS.P..P.................S.....G.G.GPYIVL...........RYANTG.VH..GE.......AP..N..AAEAVAPALAHLPHSVGPAVAG-c.........................................
A0A7W9PQJ4_9ACTN/57-148 ..............epa---ETAWSILL...........AD.DNHISH......----REMLAALRSNSRLSGMFPFFSHD..V.LRLAID........P....-F..KRD....AGEI.CI.E..P.................Q.....G.D.GRFSVQ...........SSPGGE.IL..AD.......VE..L..AD---------------------ladmas....................................
A0A2I0SH60_9ACTN/1-104 ................m---AVRWRQLR...........EA.AARMPD......-TALHDLVEAAFQQERLRALSPGRSTY..W.LTFSRR........A....AP..PVC....NDLP.GA.M..P.................I.....G.N.GRCRVR...........-FADG-.RQ..QE.......SD..S..AAEAVAAVLAGLPDDAVP-----rt........................................
A0A1Z2KY42_9ACTN/12-119 .................ETVALEWLRML...........SM.EERLIS......----PEMVRAAHAHPRLRVLSPTVSHG..S.LQLSRC........T....RS..PWT....RDVP.AL.F..R.................R.....S.G.GGYTIV...........HFGHGG.II..GE.......PD..T..IEEAIDLIVANLQPGYGPAVDGT..........................................
G8S6N8_ACTS5/126-208 .................EMVAAQWRSLL...........AA.PEYRDE......----RPLLAAVHRSPRARRLFPVLTHG..M.LRLSAD........M....GR..VGG....REIR.IV.P..L.................-.....R.H.GGHRIE...........------.--..--.......--..-..-----------------------dgagtvlatles..............................
A0A810NVM4_9ACTN/57-160 ................d-AVEVAWLSLY...........EN.HTGDAV......RARLHAFVALAFYEPRLRRLRPFTSHW..M.LVFSRS........P....TF..PWS....RDCP.SV.D..P.................L.....E.P.GRYRVR...........TAE-GR.EL..GV.......-A..D..AAGSLALVLAAL-----------dtvaa.....................................
A0A4R5AGP9_9ACTN/113-222 ................n-TVEVQWATLL...........ED.ADLKNR......---MHELLATSCDNPTLRKLFPWVGQHgsR.LGFSRC........T....GY..PYT....KDIP.VI.D..L.................-.....T.E.GYFRVT...........DISSAI.VL..GV.......FV..N..LLDALNVVIDGIPAWVGPAVPGT..........................................
A0A2L0N8K6_9ACTN/111-220 ..............dpv---ELMWMIKL...........DR.VHLPPYd....rHPRPHALLAAAYAQPVLRRLMPVNSHF..N.LWFSTT........V....ET..PWR...aKVGG.TV.D..P.................N.....H.E.GRYAVW...........--NDGG.PV..AC.......FD..T..AEEAVALVVARLPEGAGPA----r.........................................
A0A495JDS7_9ACTN/128-252 ................e-AIAFRWQRLL...........DP.PPPRAR.....hLYGLHDFLVAASGEPRLRALYVFTSHY..D.LGFRRS........V....PN..GQS....RALA.WV.R..P.................L.....G.E.GRYLIA...........GADRRQ.--..--.......--..-..-----------------------lypdgpmgrtgwdtdsvagvlgpapaqesvalvltamdrdvq
A0A239GEI2_9ACTN/133-244 ...............ll--AESEWRGLR...........NE.ARTVV-......VPGYRALVEEAYAVPALRALYPFRIGW..A.LCFSTT........T....RP..DLT....VTGP.RL.R..A.................Y.....D.T.DEFTVT..........eDLVGGG.VL..AV.......TA..T..AREAVAVAVRRLPGGLGPVRSG-a.........................................
A0A124G8X4_9ACTN/93-206 .................RVVSTAWRLTL...........ER.SRVIRL......--GDAELAEALYAQPALRVFFPWPSHG..Q.FSLLSS........T....AD..PFH....NELP.RV.I..P.................T.....I.D.GLWDVVae.......gsTQTPSR.VL..GA.......RL..S..ASEAAALVAANIPAGSGPAIEG-g.........................................
A0A285K8W5_9ACTN/5-96 ......gerpgpigarl-----------...........--.------......----APFLALAFREPRLRELRPYTSHW..T.LLFSRT........A....EW..PFT....RTGP.AV.A..P.................T....sT.P.GRFVVD...........SRKGHP.S-..-P.......EI..G..AATALHLVLTHLPA---------sr........................................
A0A7Y8X4D7_9ACTN/10-125 ..............esv---EARWQRLPttwrlmldrgdSQ.AAAA--......GRGVLALIEAASAQPELRRLYPFTTRC..V.LRFGSG........G....GL..PTE....TDTP.AV.E..S.................L.....R.D.GRFRVL...........SPTLTR.VI..GE.......TD..T..ADAAVALLLAQLPA---------apdq......................................
A0A7K2QAK3_9ACTN/10-121 .....dcvearwqrlpt-----TWRLMH...........ER.GGSPVL......SRGVLALIEAASAEPSLRRLYPFTTRF..T.LWFSAR........T....SH..PFE....VVAP.AV.E..P.................L.....P.G.GRFQVL...........SPTRKR.VI..GE.......AD..T..ARAAVALVVAGL-----------aqap......................................
A0A2Z4UXA1_9ACTN/133-246 .................RMVEAEWQFMR...........RQ.AAELEYd....wQATYQALIEAAYAEPALRALYPFTSHW..A.LRFSSI........T....RP..GLE....IVGS.SL.C..A.................N.....G.D.GTYGLG...........RGFMTM.DL..GT.......FS..T..PQEAVALAVRHLPDGLGPVTRG-v.........................................
A0A7W8EIA6_9ACTN/3-114 ................p---ESHWAGLL...........ADyAPPHPErs..wfEPRLWPLLRAAAGQPALRRVYPIISLN..R.LTVFHS........Pe.vfRR..APE....DRWP.AV.V..V.................G.....S.D.GLYAVV...........SDVWSD.EA..TM.......VL..T..T----------------------adpglaaeklaslvee..........................
A0A2I0STI9_9ACTN/14-135 ................a-IVEAQWLSLQlawq...wkrdVH.EIRSPGr....pCPGIVPLLKAAAAASRLRRLYPFTSHF..A.LLFSSR........T....GY..PWT....VQAG.SV.E..P.................L.....R.N.GSFRVR...........RRDPSA.VI..GE.......VE..T..AEEAVDLVVGLLPADFEPVIT--vp........................................
A0A426UFH6_9ACTN/3-61 .................RTVEAAWHQVL...........TT.AGEARPpeesplFAAFAELVLVAHAEPLLRQLCPWTGMW..E.LHFSM-........-....--..---....----.--.-..-.................-.....-.-.------...........------.--..--.......--..-..-----------------------i.........................................
A0A066YLM1_9ACTN/133-246 ................r-LIASAWQRLR...........DE.AAGLDHp....wAPTHRQLVEAAHAEPVLRVLFPFTSHW..A.LRFSTT........T....GP..AMA....AVGP.VL.A..A.................G.....G.D.GTFGVG...........TGLGAP.DL..GS.......YP..T..AREAVARAVRELPPVLGPVTLG-g.........................................
A0A2L0NBE0_9ACTN/57-168 ................t-AIETMWTIYR...........QV.AASHVD......----HDLIEASYAQPQLRALFPFHSHM..S.LNFSRC........T....GF..PYT....HDVP.VV.T..P.................-.....V.D.GKYRVTww......ktrSPHGPA.DI..GE.......AD..N..PRDAVALVVAHLPPECGPAVVGT..........................................
A0A5N8W1C1_9ACTN/1-91 ...............me-----------...........--.------......----SELVRAAYAEPRLRQLFPWTGMW..E.LHFSRC........I....ES..PWT....WDVP.YI.R..P.................Q.....P.G.GRFRVE...........GPSRTE.FV..GE.......AD..S..VEAAVAMVVDRLPPGCGPAVV--nr........................................
L1KKP7_9ACTN/132-248 .................RVVSTAWRLTL...........ER.SPVIRL......--GNAEVAEALYAQPTLRVFFPWPSHG..E.FSLLSS........T....QD..PFY....EEVP.RV.V..P.................S.....G.D.GLWNVVlhw....srwsPQIPSR.VI..GS.......RL..S..AREAAALVAANVPPGSGPAIEG-g.........................................
A0A7H1BID7_9ACTN/1-96 ...............ms-----------...........--.------......----AELVVAAYAEPRLRQLFPWVGMW..E.LHFSRC........T....EQ..RWT....WDVP.YI.G..P.................TaagpgH.A.GPYYVE...........GPSRTQ.KI..GR.......AD..T..AQEAIAMVVERLPSNCGPAFHGT..........................................
A0A8J4DE41_9ACTN/9-114 ................a-IVEAAWQAVR...........AD.GRVR--......----TELLDAAYGEPRLRQLFPWTGMG..E.LHFSRC........T....SP..RWT....WDIP.YI.Q..P.................A.....E.G.GGYWVS...........GPLRSE.TV..GP.......AA..T..AEEAVAMVLERLPHGCGAAFVG-s.........................................
A0A1C4NCC7_9ACTN/142-257 .................EAVTVRWRLLLdh.......lrED.ADGLAL......AGRTLALVETASAEPKLRQLYPVTSHW..S.LHFTTC........T....GF..PYS....WDVP.FV.D..P.................L.....S.D.GRYRVC...........GPARGT.VI..GE.......AD..T..AEQAVAMVVGALPADCGPAVAGT..........................................
A0A0M9ZU55_9ACTN/1-87 .................-----------...........--.------......------MLEAAYTEPRLRQLFPWTGMG..E.LHFSRC........T....EQ..RWT....WDIP.YI.Q..P.................A.....A.G.GEYWVS...........GPLRSE.SV..GP.......AA..T..PAQAVTMVVERLPPGCGPAFVGT..........................................
A0A8J4DGG2_9ACTN/16-106 ..............amv------WETLL...........AD.PD----......LTRIGALLRAAHADDRLRGRMPHVRHY..A.LSFDAS........G....EP..GEE....---V.CI.V..P.................L.....S.N.GRYVVE...........---AAG.EA..TP.......AD..D..APRAVAMAAAAI-----------dea.......................................
A0A0N0TU97_9ACTN/1-63 ................m-----------...........--.------......--------------------------H..R.LTFSRR........A....AP..PIC....RDLP.AV.G..P.................L.....R.D.GRYRVR...........FPDR-T.S-..RE.......AD..G..AAEAVAMLLDGLPDDAVP-----ll........................................
A0A250VIR1_STROL/135-239 ................q-LTESEWQHLR...........TE.ARELD-......WPEYYALIEAAYAEPALRCLYPFTSHW..T.LRFSTN........T....RP..DLT....VVPM.CL.D..A.................H.....R.E.KPYTVS...........ASYMGE.VL..AE.......TT..T..AEEAVAAAVRHLPQA--------ad........................................
A0A0N0T4I8_9ACTN/132-243 ................s-VVELQWRTMR...........EE.AAEAPD......FPAFGELVEAAHADPKLRQLYVFSSHW..T.LGFSSC........T....GF..PFR....VEVA.IA.P..S.................R.....N.G.GPYLVM...........EHPHSI.VI..GE.......TA..M..AEEAVAAAVSRLPAGLGPAVAGT..........................................
A0A239P7M0_9ACTN/131-229 ...............rr---AARWLWLH...........EN.HCADQV......ATRLGGFVALAFHEPRLRALYPYTSHW..N.LSFSTT........S....QW..PFT....RDHP.VV.A..P.................G....aD.A.GRYVVG...........-TRDGR.V-..HD.......ET..D..AAGALRLVLA-------------ew........................................
A0A2G1X9Z8_STRCJ/12-118 .................ETVALAWQRVL...........SL.EEDLLA......----PEIARAAYAEPRLRELFPLVSHG..A.LTLSRC........T....RS..PWS....NDVP.TL.Y..R.................R.....A.G.GGYVVI...........-RYGEG.RL..GE.......PD..T..VEEAVALIVANLPAGCGAAVDGT..........................................
A0A561S9P3_9ACTN/131-240 .................EVIASEWQWLL...........KD.AGRAD-......WPQYQALIESAHAEPKLRRLYPYTSHW..A.LGFAEK........P....DG..PYSa..pSFVS.IG.S..P.................R.....G.T.GDYTIR...........EWWNGP.AL..HH.......VA..T..AAEAIAIAVDRIPADLLQ-----tf........................................
A0A101V3S6_9ACTN/126-237 ................a-AVDVQWRLMR...........EW.AATKPD......FPEFGLLVEAAHAEPRLRQLYPISSHW..T.LGFNVS........T....GV..PSR....VATA.VV.P..A.................Y.....E.G.SPYRVQ...........KFLHAG.LI..CE.......AD..T..AEEAVAFAVAHLPTDLGPAVAG-v.........................................
A0A7K2QPJ1_9ACTN/129-230 ...............es--IPAQWTWLK...........TS.DVFIEE......----RPLVEAFHEDGRFNEFFPNLSHG..T.LRLSTN........H....GV..QGA....REV-.CV.T..P.................T.....S.G.DTYRVE...........DTGVRS.SA..RT.......AA..S..LQEALAVAAEFLTAG--------rsg.......................................
I2MYW4_STRT9/13-120 .................EIVAGQWQWLL...........AA.GPEHVR......----PDVVRAAYANPRLRGLFTGLSHG..V.LFFSLS........T....ES..PYT....LVGG.TV.Y..Y.................L.....E.N.DRYFVR...........GAPVTS.SL..GE.......TD..S..LKEAFALLAANIPDDAGPVVAG-p.........................................
A0A1H7G4M4_STRJI/3-98 .............pddr-----------...........--.------......HPRAHALLAAAYAQPVLRRLLPVNSHF..N.LWFATS........V....EE..PWK....FRVG.HVrC..P.................D.....E.D.GLYGVR...........--RRGE.PV..AR.......TE..T..PEEAAALVVAALPAGLGPVVT--sp........................................
A0A327ZBD2_9ACTN/11-132 .............eird----ATWDGTL...........AC.TGDDWV......AMRLRQLAAAAQGTP-LRNLFPYTSHN..S.LHFSRC........S....HY..PFT....QDCP.WI.W..F.................A.....P.E.PHFVAYaphptgiqgnlADSQPP.VL..LD.......TD..D..PAAAVAAAVQALPPHYGTVWIG-s.........................................
A0A0F2TGZ8_STRR3/131-239 ................d-VIAAEWQYRL...........KE.ARDTD-......WPEHLALVEAAYAEPRLRRFYPFTSHW..A.LRFSRL........P....RP..FVP....SFAT.LS.A..P.................K.....G.G.GTFRVS..........eWGAEGS.AE..TR.......VA..T..AAEAVAIAVDRITAEFEA-----ag........................................
A0A2R4FMJ2_9ACTN/133-237 ................r-LIESEWLCLR...........KE.AAEVD-......WPEHHALIEAAYAEPALRQYYPFKSHW..T.LRFSTS........I....RP..KLT....IVPV.CI.L..A.................G.....L.G.EDYTVS...........AGYRQQ.HL..GE.......TA..T..AEDAVALAVRNLPADF-------t.........................................
A0A7W9UPR3_9ACTN/103-202 ..............dpa---AAKWRQLL...........SS.DWHLRD......----RPLLEAAHAHPDLRVFYPYISMG..S.LMLSRK........P....-F..DLE....SGLV.KI.I..P.................F.....S.E.DHYRVT...........-MWPAA.FR..RD.......MT..S..LNEALDVAVA-------------cfrslpd...................................
A0A2D3UE37_STRC0/12-120 ................e-VMAGEWRHLL...........EG.SQGLID......----TETVRAAYAQPQLRQVFPMVSHG..V.MYFSRC........T....GL..PAA....HVGG.QV.H..P.................R....gI.D.GRFWVR...........GPMGVG.TI..GR.......AK..T..LEEAFALVAANLPEGCGPAILGT..........................................
A0A372JRW8_9ACTN/1-96 .........mrddgrvr-----------...........--.------......----TELIDAAYAEPRLRELFPWTGMG..E.LHFSRC........T....GQ..RWT....WDIL.FI.Q..P.................-.....A.R.EAYWVS...........GPSRSE.TL..GP.......VA..T..AAQAVAMVVQHLPEKCGPAFVGT..........................................
A0A7K0CPL8_9ACTN/28-149 ....aavdacwenlllh----WHWRHAA...........NE.ALRPGR.....pVPPLIPLVTAAAAEPRLRRLYPYTSHY..F.LRFSST........T....HY..PYA....NQGG.MI.E..P.................L.....I.N.GNFRVH...........RRDPHA.DL..GE.......FT..T..AEEAVARVVRLLPDT--------dpevtagr..................................
A0A1J4Q0E3_9ACTN/133-243 ................r-LAESEWQHLL...........TE.ADEAD-......WPEYRALVEAAYAEPALRGLYPFTSHW..T.LRFSTS........T....RP..RLT....VIPL.CL.D..A.................H.....R.D.SRYTLS...........ASIMGE.VL..VD.......TI..T..VADAVSTAVRHLPSGLGPVTSG-a.........................................
A0A177QNR0_9PLAN/137-192 ................a-EVERKWQALY...........RH.IKSDEY......KANLIPLVETAMEVPVLRRLFPYTSLV..W.LWFSRI........-....--..---....----.--.-..-.................-.....-.-.------...........------.--..--.......--..-..-----------------------dvd.......................................
B5H9Z6_STRE2/11-118 .................ELVEAEWNRIL...........GY.GPDRID......----PLVARTAYTHPALRELFPMVSHG..I.LYLSRC........T....QY..PWT....HDVA.TA.F..P.................Q.....A.A.GGYRVR...........RQSDNT.LL..GA.......VE..T..VEEAYELIAANLPEGCGPAVDGT..........................................
A0A1C4VZA9_MICEC/6-113 ...............di---TTAWRYLR...........EK.TPNTRQ......--GDPLVVNAAYAQPRLRALFPFPTHG..T.LRFLRT........A....PP..RQS....EEID.SL.PfiV.................C.....G.E.PPYQVY...........AAGYSE.LL..GT.......AA..T..PEEAAALVVAHLPEDAG------sdr.......................................
A0A1S2PN66_9ACTN/13-125 ...............dp--VAAHWQLVR...........EM.NENLID......----KHLVEAAYANLALRSLFPMVSHG..S.LQFSRC........T....RF..PWS....QDLP.SI.F..P.................L.....D.G.ERFRVLrl......hepQGSGRE.RI..GG.......AF..T..AEEAVEIAAAHLPDGWGPAVDG-e.........................................
A0A250VE80_STROL/6-120 ............rqpal-----VWQWRR...........ER.QEVLRPg...vgYPGIVHLVEVARAERALRQLYPYNSHC..A.VRLSSR........T....RY..PYA....LRAP.SV.L..P.................R.....H.D.GRFRVF...........VARGGT.LR..GE.......TG..T..AEAAVALVVAHLPAGLRPAVAGT..........................................
A0A2S4XSY7_9ACTN/131-226 ................d-LIEAYWRTLL...........RE.VS----......-PGLHSIVTEAHEQPRLRAMFPMESHN..R.FRVVSD........L....GK..PWD....--TP.YI.R..L.................K.....H.P.EGFELV...........SAGQAG.EI..L-.......--..-..-----------------------aegdartvigayvralrr........................
A0A810MWW3_9ACTN/113-213 ...............rr---EASWLWLY...........EN.HGANPI......GARLRAFVALAFHEPRLRALLPYTSHW..T.LRFSTK........Q....GW..PFS....LDLP.VV.D..P.................A....pT.P.DRYVVR...........-TRD-G.RA..HD.......ET..D..AAGALRLVLADLP----------g.........................................
A0A2A4KDB0_9ACTN/5-115 ................t-VVEKTWRGIL...........ER.HPGARR......--GEPAVIEAAYAEPRLRALFPFPSHG..A.LSFHRN........T....QD..PWS....NDLP.FI.V..G.................-.....D.V.ESCIVYa.........pLGVPQR.VL..GE.......SL..T..PQEAAALVVAHLPPDCGPAFDG-p.........................................
A0A117PTJ6_9ACTN/133-246 ...............cl--TESEWQSMR...........QE.ADELAYa....wQEAYQALIEAAHAQPTLRSLYPFTSHW..A.LRFSTT........T....RP..RLT....VVGP.CL.M..A.................N.....S.D.GTYGVG...........KGFISQ.DL..GQ.......FA..T..AHEAVALAVRHLPSGLGPTTLG-g.........................................
A0A2R4SYV2_9ACTN/133-244 ................r-LTESEWQGMR...........TE.ASARE-......QPGYHALVEAAYAEPALRGLYPFTSHW..A.LRFSTT........T....GP..WMS....TVGP.CL.L..A.................D.....D.V.DRYTVS..........aGFTGSG.LI..AQ.......AT..T..AQEAVAAAVRHLPSGLGPVTSG-a.........................................
A0A8J4DVW3_9ACTN/132-233 ..............dhr---ESKWLWLY...........EN.HCADRV......AARLSAFVALAFHEPRLRALRPYTSHW..T.LCFSST........P....QW..PFS....REHP.TV.T..P.................V....eA.P.DRYLVR...........TPDG--.RT..HD.......ET..D..APGALGLVMAELP----------g.........................................
A0A066YHZ0_9ACTN/128-233 ...............de--VELTWRQRLg........hlDL.RGPHRY......PPGYRAMFRAAFAEPRLRRLTPVTSHH..T.LWFATT........T....RH..PYQ....RVGP.AV.E..P.................R.....Y.D.GTFLVR...........--VQGG.EP..VE.......VA..T..AEQAVALAVDGLPTG--------y.........................................
A0A8J7DYA5_9CYAN/34-147 ................e-YVEFVWKKLL...........LC.QPEDFS......SPELFSLIHAASLVPELRSLIPYTSML..S.LRFKCK........T....DD..LDW....NDYP.CC.L..A.................M.....R.N.GEYSVQi.........yKQAILM.TI..TK.......SK..N..INDVIKALVQALPKSCGDATD--dm........................................
A0A2S9PSS0_9ACTN/10-121 ................r-LAESECRQLR...........AE.AGEVG-......SPEYRALVEAAYEEPVLRGLYPFTSQW..A.LRFSRT........T....RP..GLD....VVGP.WL.L..T.................Q.....S.A.GLYMVS..........eGPVWGS.EW..AR.......AG..S..AREAVALAVRRVPRGVGPVAAG-s.........................................
A0A3E0HNS2_9PSEU/120-217 ...............dr--IELAWQHFR...........LS.GPFE--......---LGAFVEAAMREPRLRRMCPFTSMW..W.MSFR-P........T....AD..EYL....VPGP.WV.R..S.................A.....H.N.GRYTVV...........VNRREE.P-..TI.......DH..D..AETAVRLVLAEM-----------drig......................................
A0A0Q8PV76_9ACTN/133-246 ................r-LTESEWLGMR...........QE.AADLEYd....wQEPYQALIEAAYAEPALRALYPFTSHW..A.LRFSTT........T....RP..ELT....PVGP.CL.A..A.................G.....S.D.GTYGLG...........RGFITP.DL..GL.......FT..T..AREAVALAVHHLPPGLGPITL--ds........................................
A0A5Q0LPR8_9ACTN/1-88 .................-----------...........--.------......------MVQVAYAEPQLRQLCPWAGMW..E.LHFSRC........T....GF..RPT....WDIP.YI.G..T.................L.....T.D.GRYYVE..........gPHRNSP.RI..AE.......TD..S..AQAAVAMVIERLPPGCGPAFAGT..........................................
A0A841BH59_9ACTN/145-255 ................y-IVTGEWDRLL...........RE.ADEAN-......WPEYRALIMAAYAEPRLRQLYPYTSHW..M.LRFSTT........T....GY..PFS....PDIV.CL.T..A.................S.....E.D.STFTVR...........ENWMGP.TI..GT.......AA..T..AEEAVLIAADLPPPGLGAAIAG-p.........................................
A0A239NV45_9ACTN/26-90 ................r-FTESEWQSLR...........LG.AAEMEYd....wHETFQALIEAACAAPALRALYPFTSHW..A.LRFSIT........T....RP..DLT....VA--.--.-..-.................-.....-.-.------...........------.--..--.......--..-..-----------------------gr........................................
A0A2X0IJM6_9ACTN/1-95 ...............mp-----------...........--.------......FPAVRDLVEAAYAEPKLKQLYPFTSHW..G.LHFSTC........T....GW..PFT....WVVP.FI.D..P.................L.....R.D.GRFRVS...........GPNRRT.VI..DE.......AD..T..AAEAIDIVVAHLPDNLGPAFAGT..........................................
S4NUJ6_9ACTN/125-238 ................r-LTESEWRGML...........QE.ASELEYa....wQEAYQALIEAAYAEPALRALYPFTSHW..A.LRFSTT........T....RP..GLT....FMGP.CL.T..A.................G.....S.D.GTYGVG...........RGFVTP.DL..GL.......FT..T..AREAVALAVRRLPAGLGPVALG-g.........................................
A0A250VFE0_STROL/133-246 ................r-LTESEWQGKR...........RE.AAELEYa....wQETYHNLIEAAHAEPALRALYPFTSHW..A.LRFSTT........T....RP..DLT....VVGP.CL.S..A.................N.....S.D.GTYGVG...........RGLISQ.DL..GQ.......FA..T..AQEAVAVAVRQLPSGLGPTTLG-g.........................................
A0A0M8SLM4_9ACTN/1-89 ...............mr-----------...........--.------......------IAEAAYAEPRLRRLYPFTSHR..S.LHFTTC........V....GI..PYS....RDVP.HV.D..P.................L.....S.N.GRYRVH...........APSRRT.VI..GD.......AD..T..PQGAVALVVSGLPAGCGPAVAG-p.........................................
E4N2A6_KITSK/101-211 elhwrlrlqglghgrhp-----------...........--.-----G......PDRVLELWRAAFAEPRLRRLYPISSHH..N.LWFSTG........L....GP..PYE....SVGL.LI.V..P.................H.....S.D.GTYEVR...........YHRGSS.AV..AEalpepvaVA..T..AAEAVAVAVAALPPQ--------a.........................................
A0A1I2E3H0_9ACTN/14-104 ................e-MIGERWRRLL...........DV.PPGRAP.....hLHDLHDFLTAAAAEPRLRALCPFTSHQ..D.LGFRRS........V....AE..TPS....RALA.WV.R..P.................F.....G.E.GRYLIA...........GPDRRG.L-..--.......--..-..-----------------------htpgpqp...................................
A0A081C249_9BACT/124-209 ..rfvethwlefapyvf-----------...........--.------......-FELNPFFEAAKEHPILRQLYWATSHR..A.FHFSRS........P....GL..PWL....NDCP.GV.E..R.................-.....-.-.------...........------.--..--.......--..-..-----------------------icpvrsfsvalrnispaerqrire..................
A0A2I0SN57_9ACTN/59-168 ................g-AVELTWCAKL...........DR.IHMPPYd....rHPRPHAVLAAAYAQPVLRQLMPVNSHF..N.LWFSTG........V....EE..FWK....TRVGyLI.C..P.................Y.....D.E.GLYGVR...........--NKGR.LV..AR.......TE..T..PEEAVALVVAALPEEFGPA----s.........................................
A0A429A4R3_9ACTN/131-242 ................d-IIASEWQWML...........KD.ARDAD-......WPEYQALIEAAYAEPRLRRLYPYTSHW..A.LGFSST........P....DY..PFS...rPFVW.ID.A..P.................R.....G.A.GGYTIS...........EGRNDP.DP..MQ.......IP..T..PAEAIAIAVDRIPADLQQTS---len.......................................
A0A7Y6Q0T6_9DELT/122-218 ..............rdr-----RWRSLA...........--.-TTSSD......-PEVRFVAERLAEEPEVRRYYPYTSMS..N.VKLSRN........D....EY..PWD...dEGLP.RL.I..R.................R.....E.E.GEYVVV...........--DGEG.EL..RG.......TG..G..LESAVAAFVRLL-----------adi.......................................
A0A4Q6I6I9_9ACTN/14-65 ...........lnrghd-----------...........--.------......---------------------------..-.------........-....--..---....-DLP.FI.L..Y.................-.....G.G.PPYNVY...........SSGYAD.LL..GE.......VA..T..PAEAAALVVRHLPPNV-------vm........................................
A0A2A3HPC9_9ACTN/9-114 ................a-LVEAGWQKVR...........AD.GRVR--......----PELFEAAYAEPLLRQLFPWTGMG..E.LHFSRC........T....EQ..RWT....WDIP.YI.Q..P.................A.....A.E.GEYWVS...........GPLRSE.SV..GP.......AE..T..PAQAVAMVVERLPPGCGPAFVGT..........................................
W7STR1_9PSEU/112-216 ...............dr--IEYSWQSAL...........VH.DPF---......--GLTGFIAAAMNEPRLRTMYPFVQMG..W.MSFRP-........T....VD..EFL....VPGP.WV.SgsR.................Q.....D.D.GVFKVCs........vdRDRWHG.EP..LA.......VG..D..AETAVRVVVAEM-----------drlgv.....................................
#=GC seq_cons ................t..hthpWphhh...........pp.stth..........t.tsLlcAAaAcPpLRpLaPaoSHh..s.LpFSps........T....th..shs....hshP.hl.t..s.................h.....s.s.GpYtVp...........t.ttst.hl..up.......ss..o..sp-AlAhsltpLPssht................................................
//
