#=GF ID DUF6200
#=GF AC PF19702.3
#=GF DE Family of unknown function (DUF6200)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 26.90 26.90;
#=GF TC 58.90 58.80;
#=GF NC 25.90 25.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 29694699
#=GF RT Biosynthesis and Heterologous Production of Vioprolides:
#=GF RT Rational Biosynthetic Engineering and Unprecedented
#=GF RT 4-Methylazetidinecarboxylic Acid Formation.
#=GF RA Yan F, Auerbach D, Chai Y, Keller L, Tu Q, Huttel S, Glemser A,
#=GF RA Grab HA, Bach T, Zhang Y, Muller R;
#=GF RL Angew Chem Int Ed Engl. 2018;57:8754-8759.
#=GF DR INTERPRO; IPR045680;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0001943) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, NRP (non-ribosomal
#=GF CC peptide). It includes a member from the vioprolides A
#=GF CC biosynthetic gene cluster from Cystobacter sp. [1]. This family
#=GF CC appears to be predominantly found in bacteria.
#=GF SQ 20
#=GS A0A3N6R8G1_9CYAN/5-77 AC A0A3N6R8G1.1
#=GS A0A3N6R2Y8_9CYAN/1-66 AC A0A3N6R2Y8.1
#=GS A0A2P1PQV5_9GAMM/40-118 AC A0A2P1PQV5.1
#=GS A0A844M6M2_9CYAN/3-75 AC A0A844M6M2.1
#=GS A0A261KPY0_9CYAN/492-560 AC A0A261KPY0.1
#=GS A0A1Y6DB08_9GAMM/3-75 AC A0A1Y6DB08.1
#=GS A0A8J2Y0X7_9PROT/2-71 AC A0A8J2Y0X7.1
#=GS A0A1L9QP23_9CYAN/1-67 AC A0A1L9QP23.1
#=GS A0A4U1IUD9_9DELT/1-78 AC A0A4U1IUD9.1
#=GS A0A0K1ED96_CHOCO/12-88 AC A0A0K1ED96.1
#=GS A0A4U1GZT2_9DELT/24-93 AC A0A4U1GZT2.1
#=GS A0A8J6ZWE2_9CYAN/1-72 AC A0A8J6ZWE2.1
#=GS A0A8J7DFC6_9CYAN/1-75 AC A0A8J7DFC6.1
#=GS A0A1A6FIJ0_9HYPH/6-82 AC A0A1A6FIJ0.1
#=GS A0A3N6P4J5_9CYAN/1-66 AC A0A3N6P4J5.1
#=GS A0A261KJI1_9CYAN/2-74 AC A0A261KJI1.1
#=GS D0LS35_HALO1/1-77 AC D0LS35.1
#=GS A0A1I3ZJ55_9PROT/1-74 AC A0A1I3ZJ55.1
#=GS A0A4V5PL51_9DELT/1-69 AC A0A4V5PL51.1
#=GS F4XM08_9CYAN/1-67 AC F4XM08.1
A0A3N6R8G1_9CYAN/5-77 ..........s-DTSEKSLKQQANT---VVLEFGGA.KSDDIDDLRRGEG.KVFKRIGQTIEKLQ.E...SGEISDNI.QPIIVILKKKKSKKG...
A0A3N6R2Y8_9CYAN/1-66 .........mk---------QKTN---TIILEMGTA.KSKDIRDLQRGEG.KISKNIGKMIKQLK.A...SGETPEDA.QPVIIIVRKKREKKG...
A0A2P1PQV5_9GAMM/40-118 ..........l-PNQQRNFLMTNASVPPIVIDLGAR.KKKHIRQLKNGRG.AAQDEVARVLESVRtD..lAAEAEGKIlVPVVIVYRRKRKRAG...
A0A844M6M2_9CYAN/3-75 .........et--KSESSKSKEANT---IILEFGRQ.KKNRIRDLREGRG.RLFKKVARTISELQ.K...AGEVGDSV.QPVIVIVKQKRSS--sk.
A0A261KPY0_9CYAN/492-560 ........klg---KEENKKQEANT---ILVNYGKA.KNDDIKDLYRGEG.KLLENISDVVAQLK.Q...SGDVERNA.QPLILIVEKK-----g..
A0A1Y6DB08_9GAMM/3-75 ..........t-QTSEQTLNAEDTAPGMIILDVGTQ.NAKRIKKLCKGKG.KLLRKVDEAVDQLR.D...AGKVKRDA.QVVLVVVRKE-----vg.
A0A8J2Y0X7_9PROT/2-71 sgseikeptkg---------------IVCVLDLGEQ.SRKRIRSLRRGEG.RLMEKVEDAVAALK.E...DGVLDASA.QTAVIVVRQE-----ags
A0A1L9QP23_9CYAN/1-67 .........ma----------TAQKENTIILEIGNA.KKDDIDDLRYGEG.KLFKRIQSTIERLK.D...DGQVGENA.QPIIVIVKKKKEK--d..
A0A4U1IUD9_9DELT/1-78 .msdeasnvev------------EQITPIVLKVGKR.KRSAIKDLKRGRG.RLMDEVEQTLDEVRiGl.gAEGARKEL.VPVVILYRQKDKRR-kg.
A0A0K1ED96_CHOCO/12-88 ..........k-AATRPGTTGEAGGKEPIIVDLGKK.SRKQVRSLSKGKPcRLLRRVEETVEQLR.T...SGEIGDNV.RPLIVVVRQRPRKKG...
A0A4U1GZT2_9DELT/24-93 .....aeggle-------------GEEPIIIDLGKK.SKKQVNKLRKGKPsRLLRRVEDTVEQLR.A...SGEIGEHI.KPIIIVVRQRQRQKG...
A0A8J6ZWE2_9CYAN/1-72 ....mklqegr--------RKKANT---IILEFGSQ.KKDLIRDFRQGRG.RLFKKVTQAISELQ.K...AGEIDNDV.QPVIAIVRQKKS---ikt
A0A8J7DFC6_9CYAN/1-75 ......msktp------STSSKPEKTDTIILEFGSQ.KKDRIRDLREGRG.RLFKKVAQAISELQ.E...AGEVGDSV.QPVIVIVKQKKSNKG...
A0A1A6FIJ0_9HYPH/6-82 ..........d-NGSSAKTAEASPVSEMCIIDIGEH.GRRAVKRLRKGEG.KLMDKVEDAILGLR.E...EGVIGSGAtQTVVVVVREEPSLR-d..
A0A3N6P4J5_9CYAN/1-66 ..........m--------KQQANT---IILEMSGA.DKDDIYDFRRGEG.KIFKRIRSIIEQLK.E...EGEVDENV.QPVIALVQKKKDKKG...
A0A261KJI1_9CYAN/2-74 ..........v-MSGETKKPQEANT---IILEFPAA.KSDDIKDLRKGEG.KIFKKIAKTIEQLQ.E...AGEIGENV.QPVIAIVNKKKKDGG...
D0LS35_HALO1/1-77 ..........m-AEATTNKTAPSNNDSLIVVDVGKKfRRKQIRKLRKGRG.KLMGRVEQLVSDLQ.D...NDALGDNA.KPVVIVVREKKKKM-r..
A0A1I3ZJ55_9PROT/1-74 .......msea------SADVKDAKGVVCVLDLGEH.SRKRVRRLRRGEG.KLMDKVEDAIAALH.E...EGVLDGAA.QTVVVVVRQEQRL--gd.
A0A4V5PL51_9DELT/1-69 .......mvet--------------TVPIIVDLGKK.KRSALKSLKRGRG.RLVDEVEQTIDEIR.EglgQEAANKEI.VPIVIVYRKKQKR--sk.
F4XM08_9CYAN/1-67 .........ms-------TLQKENT---IILEMGSA.KKDDIKDLQYGEG.KLFKRIAKVIGELK.E...SGEVAENA.QPVIVVVKKKSEK--d..
#=GC seq_cons ..........s.......h.tpsss...IIL-hGpp.K+ccI+cLR+GcG.+Lh++VpcsIppL+.-...uG-lscss.QPVIllVRcKpcp.....
//
