#=GF ID DUF6201
#=GF AC PF19703.3
#=GF DE Family of unknown function (DUF6201)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 27.40 27.40;
#=GF TC 30.50 30.60;
#=GF NC 25.90 25.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 25351611
#=GF RT Characterisation of taxlllaids A-G; natural products from
#=GF RT Xenorhabdus indica.
#=GF RA Kronenwerth M, Bozhuyuk KA, Kahnt AS, Steinhilber D, Gaudriault
#=GF RA S, Kaiser M, Bode HB;
#=GF RL Chemistry. 2014;20:17478-17487.
#=GF DR INTERPRO; IPR045681;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0001133) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, NRP (non-ribosomal
#=GF CC peptide). It includes a member from the taxlllaid A
#=GF CC biosynthetic gene cluster from Xenorhabdus bovienii SS-2004
#=GF CC [1]. This family appears to be predominantly found in
#=GF CC Proteobacteria.
#=GF SQ 32
#=GS A0A068QTJ4_9GAMM/1-131 AC A0A068QTJ4.1
#=GS A0A2X4THM3_SALER/1-131 AC A0A2X4THM3.1
#=GS A0A068QT38_9GAMM/4-142 AC A0A068QT38.1
#=GS A0A1G7WB53_9VIBR/1-98 AC A0A1G7WB53.1
#=GS A0A1G7WD93_9VIBR/14-142 AC A0A1G7WD93.1
#=GS A0A1G7WAK7_9VIBR/1-127 AC A0A1G7WAK7.1
#=GS A9MMX0_SALAR/1-116 AC A9MMX0.1
#=GS A0A1G7WBJ2_9VIBR/1-128 AC A0A1G7WBJ2.1
#=GS A0A1G7WD06_9VIBR/1-128 AC A0A1G7WD06.1
#=GS A0A1G7WDB0_9VIBR/1-127 AC A0A1G7WDB0.1
#=GS A0A068QZM8_9GAMM/1-129 AC A0A068QZM8.1
#=GS D3UWR3_XENBS/2-65 AC D3UWR3.1
#=GS A0KJX7_AERHH/13-150 AC A0KJX7.1
#=GS A0A1M5YQ77_9VIBR/5-132 AC A0A1M5YQ77.1
#=GS D3UZF8_XENBS/4-144 AC D3UZF8.1
#=GS A0A068QVY4_9GAMM/1-129 AC A0A068QVY4.1
#=GS X2HEV6_9NEIS/3-138 AC X2HEV6.1
#=GS A0A1G7WBK9_9VIBR/1-127 AC A0A1G7WBK9.1
#=GS A0A068QSY9_9GAMM/1-138 AC A0A068QSY9.1
#=GS A0A1G7WCU7_9VIBR/1-128 AC A0A1G7WCU7.1
#=GS A0A1G7WBJ9_9VIBR/1-127 AC A0A1G7WBJ9.1
#=GS W1IVN9_9GAMM/1-129 AC W1IVN9.1
#=GS A0A1G7WAU7_9VIBR/1-128 AC A0A1G7WAU7.1
#=GS W1JB44_9GAMM/2-87 AC W1JB44.1
#=GS A0A1G7WAF3_9VIBR/1-128 AC A0A1G7WAF3.1
#=GS A0A068QRH4_9GAMM/1-137 AC A0A068QRH4.1
#=GS X2H8E4_9NEIS/14-134 AC X2H8E4.1
#=GS U3C0G5_9VIBR/3-129 AC U3C0G5.1
#=GS A0A1G7WAJ3_9VIBR/1-128 AC A0A1G7WAJ3.1
#=GS D3V2N8_XENBS/1-107 AC D3V2N8.1
#=GS X2HEX1_9NEIS/14-141 AC X2HEX1.1
#=GS A0A1G7WDQ2_9VIBR/1-127 AC A0A1G7WDQ2.1
A0A068QTJ4_9GAMM/1-131 .........m-----------LLMFFLWWFFL.SHVTFLK-ESDTRNEINSGKSEYYAKYYKPKPINLFGMYLTIMEQEpiFVVLYDKHGKYIGQTSPFNMMNIYSffeGNPTLPE......KNPQDILdthfYIVvvgdVESAYDIDINHKKWWSKIL.......................................
A0A2X4THM3_SALER/1-131 .......mmk----RVTSALFIVVLMVAWIIL.PST-IIPYSYSKVFEINSPDNKYKVIVYHGGIISPMSLYKYLKDED.yFFIIYNASGEVVFKPSPYYGTSNMG...-------......-------....---....-------------------aydgiefqygdshsllyqdqkamihtnslsdkksvniei
A0A068QT38_9GAMM/4-142 .........n-NLMKKILFLILGIILFWWFFL.SHSTFLV-GKFKVYEDTNGE--YIVKYYKPLPTNLFGMYFLTVERPpvFVVLYDINNNYIGQSSPFYMAGDLDvlgSNPMFPNnd..nsDPFHDRF....VVVnsddFSDAYEISINHKKWWSKIL.......................................
A0A1G7WB53_9VIBR/1-98 ......msvg----------------------.-------------HYIYSEDGEWKLRIYRVSVSTPVSFIQFWQEKK..YIVLYKKNGEYIGQSTPFCSQSFDD...YNILFPD......NYHSDLW....FMP....EECDFTIYIDKPKWWRKII.......................................
A0A1G7WD93_9VIBR/14-142 .....vkmfk----HIAATLISLPMLAYWLIL.SPV-IPNSENHPIYYKYSDDGRWKIAIYDISATTPISSIQYLLNRR..YVVLYKSDGEYIGQSTPFCFQSFWG...FSALFPN......NTHNSLL....FIP....ESCDYTIPTDKPEWWSKII.......................................
A0A1G7WAK7_9VIBR/1-127 ......mfkh-----IAATLISLPVLAYWLIL.SPV-IPDAKSDNVYYTYSDDGKWKIAVYDVSPTTPISLVQYLQEKN..YIVLYNENDEYIGQSTPFCYQSLFD...YNVAFPG......SNLDDLT....FLP....DECDYNIPAKNPRWWSTT-i......................................
A9MMX0_SALAR/1-116 .......mmk----RVTSALFIVVLMVVWIIL.PSTTIPY-SYSKVFEINSPDNKYKVIVYHGGIISPMSLYKYLKDED.yFFIIYNASGEVVFKPSPYYGTSNMG...-------......-------....---....-------------------aydgiefqygdshsllypgpegyd...............
A0A1G7WBJ2_9VIBR/1-128 ........mt--AKKILITLISLPVLAYWLVL.SPV-IPNKNIHKGYYTYSYDGKWKIAVYDVSPTTPISLVQYIQEKR..YIVLYNKNDEYIGQSTPFCYQSLFD...YNVAFPG......SNLDDLT....FLP....DECDYSIPAKNPRWWSKII.......................................
A0A1G7WD06_9VIBR/1-128 ........mt--IKRFIIALLSIPLLAYWLMF.SPV-IPEESLDKAFYTYSDDGKWKIAEYRVSSTTPISFVQYWQEKK..YIVLYNKNDEYIGQSTPFCYQPLFD...YNVIFPE......SDLDVLL....FVS....NECDYTIPVVNPRWWSKII.......................................
A0A1G7WDB0_9VIBR/1-127 ......mfkh-----ITVILISLPVLAYWLIF.SPI-IPEKKLDKAFYTYSDDGKWKIAEYRVQPTTPISFIQYWQEKK..YIVLYNKNDEYTGQSTPFCYQSLFD...YNVVFPG......DNLDKMS....FLP....DECDYNIPAKNPKWWSKII.......................................
A0A068QZM8_9GAMM/1-129 ..........MKVSKLLKYGVISIFFLWWFFL.SHVTFLP-SFLENGEREKDD--YHVIFYTPLPVNPLGIWYHINYPRpyFAVLY-KDNKYIGQSSPFYISNDSDmmgDNYGFP-......NNMDDYF....YIV....CCEEYNISINHKKWWSQIL.......................................
D3UWR3_XENBS/2-65 .......ttg----------------------.----------------------------------------------..-----------IGQTSPFKMMNMYSffeGNPTLPE......KNPQDILdthfYIVvvgdFESAYDIDINHKKWWSKVL.......................................
A0KJX7_AERHH/13-150 ........rl--FMKKLAMLLAVMFVAYWLLL.AHVSWDIFDKTPSVSVVSKDGKYTVFLKAVYPLNPIGIYCQLTTESpiFFELYDAKGAYVGQSSPFVCYGEWR..dVPYRFPG......EEFTSDVd..sFVIfddeYNGELNISTKHKKWWSMIL.......................................
A0A1M5YQ77_9VIBR/5-132 ..........KRLIKTIGGLLLLTFISWWLVL.SPVSFPSEN--DAYYIYSKDKKWKVGVYWVSPTSPAGLYQFLMNKR..YIVLYDANGHYIGQSTPFCFMTFDE...SNILFPS.....iTDDHNLW....FIP....ETCDYTIQVRKPAWWSQII.......................................
D3UZF8_XENBS/4-144 ..........KKTAKYILYFMLIILFLWWFFL.SHVTFLK-ESDTLSEVNSGESDYYAKYYKPEPINLFGIYLTIMEKEpiFVVLYDKEDKYIGQTSPFKMMNMYSffeGNPTLPE......KNPQDILdthfYIVvvgdFESAYDIDINHKKWWSKVL.......................................
A0A068QVY4_9GAMM/1-129 ..........MKVTKIIKYGIMFIFFLWWFVL.SHVTFLP-SFLESGERKKDD--YRVVFYTPLPVNAIGIYYYINYPRpyFAVLY-KNNKYIGQSSPFYMDDDSAmmgDNYGFPN......EKYD-EF....YIV....CCNEYNISITKKEWWSKIL.......................................
X2HEV6_9NEIS/3-138 .....rrimk-KSIKWIKI-IGLFAFFYWLCLfSSSSFYG-NFNLYTTIKSEDGEYYANIYKHLPTSPISIMQILGGNK.yFIVLYNKKGEELWRVSYFEYISEQVm.yEMISFPD......KTNNDFI....CATnhglEGHDFSTTIRN--------hkvvs..................................
A0A1G7WBK9_9VIBR/1-127 ......mfkh-----ITATLISLPVLAYWLVL.SPV-IPNKNIHKGHYTYSYDGKWQMAVYRVSPTTPISFIQYLQEKK..YIVLYNKNDEYIGQSTPFCYQSLFD...YNVVFPG......SSLDDLS....FLP....DECDYNIPAKNPKWWSKII.......................................
A0A068QSY9_9GAMM/1-138 ..........MRAIKLMKYGIIAIFFLWWFFL.SHVTFTI-GSFYVTDSKNND--FMVKYYYPAPINLFGLYFWVVSELptYVVLYDKDNNYIGQSDPFCMPHSIGiygSEYILPDis..kgDEYYERF....FISg.epFDGSYTIPVKEKKWWSKVL.......................................
A0A1G7WCU7_9VIBR/1-128 ........mt--LKRFIITLLSIPLLAYWLIL.SPV-IPNYEMSSFRYTYSEDGKWKIGLYDVSVTTPISFVQFWQEKK..YLVLYNSKGDYIGQTTPFCLQYFEE...FDILPPN......SKHNSMW....FMP....EACDYNIPIDKPRWWSKII.......................................
A0A1G7WBJ9_9VIBR/1-127 ......mfkh-----IAATLILLPVLAYWLVL.SPV-IPYKNIHKGYYTYSYDGKWKIAVYDVSSTTPISFVQYLQEKK..YIVLYNKNDEYIGQITPLCYQSLFD...YNVIFPN......RNRDDLL....FLP....KECDYSIPAVNPRWWSKII.......................................
W1IVN9_9GAMM/1-129 ..........MKVTKIIKYGIMFIFFLWWFVL.SHVTFLP-SFLESGERNKDD--YRVVFYTPLPVNAIGIYYYINYPRpyFAVLY-KNNKYIGQSSPFYMDDDSAmmgDNYGFPN......EKYD-EF....YIV....CCNEYNISITKKEWWSKIL.......................................
A0A1G7WAU7_9VIBR/1-128 ........mt--LKRFIIALLSIPLLSYWLIL.SPV-IPNSENDYAYYTYSDDGKWKIGEFPVSATTPISFIQFLFNKE..YMVLYNDKGEYIGQSTPFCTQSVLD...PNILFPT......KSDLFVR....FIP....ETCDFSIPVENPRWWSKII.......................................
W1JB44_9GAMM/2-87 yylkiflnvl----------------------.--------------------------------------VGFYYSPK..YIFLYDNDYNFIDQSSPFYFSSKLEfigGEHMLRKinlidkDKSDTEL....YISs.vrCQEGDAIAEDKKEW-----.......................................
A0A1G7WAF3_9VIBR/1-128 ........mt--FKRFIIALFSIPLLAYWLIL.SPV-IPNKNIHDPYYTYSEDRKWKIAVYDVSPTTPISLVQYIQEKN..YIVLYNENDEYIGQSTPFCYQSLLD...YNAIFPD......SDLDDLL....FLP....KECDYSIPEVKPRWWSRII.......................................
A0A068QRH4_9GAMM/1-137 ..........MKIVKYIKHIVITAIFLWWFFL.SHVTFFF--SYKNFEMNNGD--FIAKYYYVLPVNIIGIYSWIFHYQpeYVVLYDKEYNYIGQSSPFCLSNGIA..gGEHILPEkklmskNKYYAYL....NVSg.grCQDEYTIPVKEKKWWSQIL.......................................
X2H8E4_9NEIS/14-134 ......rkna----VFIKIILVLIMVMWWWFF.SSSSFYG-DFNLSDTVEGVDGEYYINMYQHLPTTPLAVYELIQGKR.yFYVLYNKQGKKIWRSPHYAYLSDGG..iHSFMLPT......KKSNL--....---....-------------------lkyfdegrkivditn........................
U3C0G5_9VIBR/3-129 ..........KKCLKFLSLTFLAFLLFWWLVL.SPVSFPNDK--YFRTIISPDHKWKLVIVPVSLTTPLSFIQALQNKS..YIVLFDEFDNYVGQSTPFCLMPIDD...FNVLFPS......KYYKDVG....IQP....EDCDYEIPTDDKKWWSEII.......................................
A0A1G7WAJ3_9VIBR/1-128 ........mt--FKRFIIALLSIPLIAYWLIL.SPV-IPNYTDEYTYHWNSKDGKWKFSIYHISVTTPISFIQFWQEKK..YLVLYNSKDEYIGQTTPFCLQSFMD...FNILLPN......RSHNSIW....FLP....DECDYSIPIDKPNWWSRII.......................................
D3V2N8_XENBS/1-107 .........m---------------------L.FPSTLFFGNWNKYFEDRGEDGQYTAVVYKKLPISPYAMWKYVILGDkyFIVLYDNKNRDIWKSSPFTSISYGAf.sASFSLP-......TANKDAF....IYP....TNDGYEVIY----------vnklk..................................
X2HEX1_9NEIS/14-141 ...rknavfk-------KNILVLIMVLWWWFF.SSSSFYG-DFNLCDTINGLDGEYYINVYEHLPTTPLAVYELIQGKR.yFYVLYNKQGKKIWHSPHYAYLYDNV...SPLFIPT......KDSKLLR....Y--....-------------------seedwsdadiknkikevygd...................
A0A1G7WDQ2_9VIBR/1-127 ......mfkh-----ITTTLILLPVLAYWLIL.SPV-IPNKNIHKGYYTYSYDGKWKIAVYNVSPTTPISFVQYLQEKR..YIVLYNKNDEYIGQSTPFCYQSLFD...YNVMFPE......SDLDDLL....FLP....KECDYSIPAVNPRWWSKII.......................................
#=GC seq_cons ........ht....+hhhhll.l.hhhaWhhL.SsV.h...s.ppsh.hhStDscaplshYpstPsoPluhhpalppcc..alVLYscpscYIGQSoPFshpshhs...hNhhhPs......pshpshh....als....pps-YsIshpp.+WWScIl.......................................
//
