#=GF ID   DUF6213
#=GF AC   PF19719.3
#=GF DE   Family of unknown function (DUF6213)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   27.70 27.70;
#=GF TC   28.80 30.70;
#=GF NC   23.40 26.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   29255990
#=GF RT   Discovery of a new diol-containing polyketide by heterologous
#=GF RT   expression of a silent biosynthetic gene cluster from
#=GF RT   Streptomyces lavendulae FRI-5.
#=GF RA   Pait IGU, Kitani S, Roslan FW, Ulanova D, Arai M, Ikeda H,
#=GF RA   Nihira T;
#=GF RL   J Ind Microbiol Biotechnol. 2018;45:77-87.
#=GF DR   INTERPRO; IPR046185;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001916) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, polyketide. It includes a
#=GF CC   member from the lavendiol  biosynthetic gene cluster from
#=GF CC   Streptomyces lavendulae [1]. This family appears to be
#=GF CC   predominantly found in Actinobacteria.
#=GF SQ   138
#=GS A0A1H4NJT8_9ACTN/10-75  AC A0A1H4NJT8.1
#=GS A0A505DKI7_9ACTN/10-75  AC A0A505DKI7.1
#=GS A0A7W7U2G9_9ACTN/10-72  AC A0A7W7U2G9.1
#=GS A0A6B2S7W5_9ACTN/10-75  AC A0A6B2S7W5.1
#=GS A0A1V9K579_9ACTN/10-75  AC A0A1V9K579.1
#=GS A0A1J4NZF9_9ACTN/10-75  AC A0A1J4NZF9.1
#=GS A0A0X3VP21_9ACTN/10-75  AC A0A0X3VP21.1
#=GS A0A1B1BDK6_9ACTN/10-75  AC A0A1B1BDK6.1
#=GS A0A514JYB8_9ACTN/10-75  AC A0A514JYB8.1
#=GS Q9FCA8_STRCO/6-71       AC Q9FCA8.1
#=GS F8JK81_STREN/10-74      AC F8JK81.1
#=GS A0A2U2Z6S6_9ACTN/10-75  AC A0A2U2Z6S6.1
#=GS A0A1X4I990_9ACTN/10-75  AC A0A1X4I990.1
#=GS A0A0L0KDN7_9ACTN/10-75  AC A0A0L0KDN7.1
#=GS A0A1V6MNQ6_9ACTN/10-75  AC A0A1V6MNQ6.1
#=GS A0A1X7FD24_9ACTN/21-86  AC A0A1X7FD24.1
#=GS A0A1Q4UYF5_9ACTN/10-75  AC A0A1Q4UYF5.1
#=GS A0A2I0SNM7_9ACTN/10-75  AC A0A2I0SNM7.1
#=GS A0A0D0PVM4_KITGR/2-67   AC A0A0D0PVM4.1
#=GS A0A101N5S9_9ACTN/10-75  AC A0A101N5S9.1
#=GS A0A6B1PVQ0_9ACTN/6-71   AC A0A6B1PVQ0.1
#=GS S5VI16_STRC3/6-70       AC S5VI16.1
#=GS A0A7W7XE17_9ACTN/10-71  AC A0A7W7XE17.1
#=GS A0A6H9UYW8_9ACTN/10-75  AC A0A6H9UYW8.1
#=GS A0A177HK80_9ACTN/10-75  AC A0A177HK80.1
#=GS D5ZVE8_STRV1/10-75      AC D5ZVE8.1
#=GS A0A2P8Q420_9ACTN/10-75  AC A0A2P8Q420.1
#=GS A0A117QQZ6_9ACTN/10-74  AC A0A117QQZ6.1
#=GS A0A6H0CI75_9ACTN/10-75  AC A0A6H0CI75.1
#=GS A0A101CE56_9ACTN/10-75  AC A0A101CE56.1
#=GS A0A7M2TB48_STRCW/10-75  AC A0A7M2TB48.1
#=GS A0A4Q7X5W0_9ACTN/21-86  AC A0A4Q7X5W0.1
#=GS A0A0L8LKF1_9ACTN/10-75  AC A0A0L8LKF1.1
#=GS A0A0M8WN79_9ACTN/24-89  AC A0A0M8WN79.1
#=GS A0A7K2TDL6_9ACTN/10-75  AC A0A7K2TDL6.1
#=GS A0A2Z4V667_9ACTN/9-74   AC A0A2Z4V667.1
#=GS A0A5R9LU34_9ACTN/13-78  AC A0A5R9LU34.1
#=GS A0A101P796_9ACTN/6-71   AC A0A101P796.1
#=GS S4MIM9_9ACTN/10-75      AC S4MIM9.1
#=GS A0A2S4YSQ6_9ACTN/10-75  AC A0A2S4YSQ6.1
#=GS A0A4Y3VEP0_9ACTN/10-75  AC A0A4Y3VEP0.1
#=GS A3KKD9_STRA7/10-75      AC A3KKD9.1
#=GS A0A0M8VJU7_9ACTN/4-68   AC A0A0M8VJU7.1
#=GS A0A1K2FUG1_9ACTN/20-85  AC A0A1K2FUG1.1
#=GS A0A5Q0LLB0_9ACTN/10-75  AC A0A5Q0LLB0.1
#=GS A0A221NTB1_9ACTN/10-75  AC A0A221NTB1.1
#=GS A0A2W2MGU8_9ACTN/10-75  AC A0A2W2MGU8.1
#=GS A0A0X3XY64_9ACTN/10-75  AC A0A0X3XY64.1
#=GS A0A0N0SWG3_9ACTN/4-69   AC A0A0N0SWG3.1
#=GS A0A7W9PQP8_9ACTN/10-75  AC A0A7W9PQP8.1
#=GS A0A4P6TQB9_STRSO/10-75  AC A0A4P6TQB9.1
#=GS A0A2A2YVJ0_9ACTN/10-75  AC A0A2A2YVJ0.1
#=GS Q826P9_STRAW/10-75      AC Q826P9.1
#=GS A0A7W7PSL5_9ACTN/10-75  AC A0A7W7PSL5.1
#=GS A0A0M8VR89_9ACTN/4-69   AC A0A0M8VR89.1
#=GS A0A2G9DV14_9ACTN/10-75  AC A0A2G9DV14.1
#=GS A0A2M9IQ42_9ACTN/10-75  AC A0A2M9IQ42.1
#=GS F3NTQ8_9ACTN/6-71       AC F3NTQ8.1
#=GS A0A089X7D0_STRGA/1-57   AC A0A089X7D0.1
#=GS A0A0M8QRE3_9ACTN/4-69   AC A0A0M8QRE3.1
#=GS A0A1H5PQG8_9ACTN/6-71   AC A0A1H5PQG8.1
#=GS A0A6G4VCA9_9ACTN/10-75  AC A0A6G4VCA9.1
#=GS A0A176L1P5_9ACTN/6-71   AC A0A176L1P5.1
#=GS A0A022M8W9_9ACTN/10-75  AC A0A022M8W9.1
#=GS A0A101UCS1_9ACTN/10-75  AC A0A101UCS1.1
#=GS A0A7X1HWD3_9ACTN/10-75  AC A0A7X1HWD3.1
#=GS A0A0U3PTF2_9ACTN/10-75  AC A0A0U3PTF2.1
#=GS A0A0M9YU68_9ACTN/4-69   AC A0A0M9YU68.1
#=GS A0A2U3A696_9ACTN/10-75  AC A0A2U3A696.1
#=GS A0A1C4LQ89_9ACTN/21-86  AC A0A1C4LQ89.1
#=GS A0A7K2FUH2_9ACTN/10-74  AC A0A7K2FUH2.1
#=GS A0A2U9NXL4_STRAS/10-75  AC A0A2U9NXL4.1
#=GS A0A101T9S0_9ACTN/10-74  AC A0A101T9S0.1
#=GS A0A7K2JHE0_9ACTN/10-75  AC A0A7K2JHE0.1
#=GS A0A1E5PLS8_9ACTN/11-72  AC A0A1E5PLS8.1
#=GS A0A250VKZ8_STROL/10-75  AC A0A250VKZ8.1
#=GS A0A2G5IHQ8_9ACTN/10-75  AC A0A2G5IHQ8.1
#=GS A0A124I7N5_9ACTN/10-75  AC A0A124I7N5.1
#=GS A0A101UUN2_9ACTN/10-75  AC A0A101UUN2.1
#=GS A0A510TDV1_9ACTN/21-85  AC A0A510TDV1.1
#=GS A0A1Q5KK65_9ACTN/10-75  AC A0A1Q5KK65.1
#=GS A0A117NYZ2_9ACTN/10-75  AC A0A117NYZ2.1
#=GS V6JLF7_STRRC/10-75      AC V6JLF7.1
#=GS A0A2H5B7V1_9ACTN/10-74  AC A0A2H5B7V1.1
#=GS A0A7Z0PTW9_9ACTN/10-75  AC A0A7Z0PTW9.1
#=GS D9VJM2_9ACTN/10-73      AC D9VJM2.1
#=GS A0A170WQY1_9ACTN/6-71   AC A0A170WQY1.1
#=GS K4RF99_STRDJ/21-85      AC K4RF99.1
#=GS A0A1A9BPF7_9ACTN/10-74  AC A0A1A9BPF7.1
#=GS D6K5F3_9ACTN/10-75      AC D6K5F3.1
#=GS A0A5N8XAV8_9ACTN/10-75  AC A0A5N8XAV8.1
#=GS A0A2Z5JV04_9ACTN/10-75  AC A0A2Z5JV04.1
#=GS A0A5N8V999_9ACTN/10-75  AC A0A5N8V999.1
#=GS A0A081XQM7_STRTO/10-75  AC A0A081XQM7.1
#=GS A0A2W6QDL8_9ACTN/10-75  AC A0A2W6QDL8.1
#=GS A0A0C5FM99_9ACTN/10-75  AC A0A0C5FM99.1
#=GS A0A1S2QKM8_9ACTN/6-70   AC A0A1S2QKM8.1
#=GS A0A0Q9A3L0_9ACTN/10-75  AC A0A0Q9A3L0.1
#=GS A0A7K3H1P4_9ACTN/6-71   AC A0A7K3H1P4.1
#=GS A0A2A3HB75_9ACTN/10-75  AC A0A2A3HB75.1
#=GS M3D8L2_9ACTN/10-75      AC M3D8L2.1
#=GS A0A117PTX0_9ACTN/10-75  AC A0A117PTX0.1
#=GS A0A0F5W600_9ACTN/10-75  AC A0A0F5W600.1
#=GS L1KZ41_9ACTN/10-75      AC L1KZ41.1
#=GS A0A4Q6IQN9_9ACTN/10-75  AC A0A4Q6IQN9.1
#=GS A0A2V4P249_9ACTN/10-74  AC A0A2V4P249.1
#=GS A0A0B5D7Y3_9ACTN/10-75  AC A0A0B5D7Y3.1
#=GS A0A1Q5MTV8_9ACTN/9-74   AC A0A1Q5MTV8.1
#=GS A0A6B2XF50_9ACTN/10-75  AC A0A6B2XF50.1
#=GS L7FHC9_9ACTN/10-75      AC L7FHC9.1
#=GS A0A0F4IXI7_9ACTN/9-72   AC A0A0F4IXI7.1
#=GS A0A7G1PAC7_9ACTN/10-75  AC A0A7G1PAC7.1
#=GS A0A6B3AT56_9ACTN/10-75  AC A0A6B3AT56.1
#=GS A0A0N0NC21_9ACTN/21-86  AC A0A0N0NC21.1
#=GS A0A2S4Y796_9ACTN/10-75  AC A0A2S4Y796.1
#=GS A0A3Q8VGG7_9ACTN/10-75  AC A0A3Q8VGG7.1
#=GS D9VLZ2_9ACTN/11-74      AC D9VLZ2.1
#=GS A0A6N7KYV8_9ACTN/10-76  AC A0A6N7KYV8.1
#=GS A0A1A5NVG0_9ACTN/10-75  AC A0A1A5NVG0.1
#=GS A0A4R1DL86_9ACTN/10-75  AC A0A4R1DL86.1
#=GS A0A1D2ILR3_9ACTN/10-75  AC A0A1D2ILR3.1
#=GS A0A426ULS4_9ACTN/10-75  AC A0A426ULS4.1
#=GS A0A5N8W6A3_9ACTN/10-75  AC A0A5N8W6A3.1
#=GS A0A7K2KTE5_9ACTN/8-73   AC A0A7K2KTE5.1
#=GS A0A3M0I410_9ACTN/10-75  AC A0A3M0I410.1
#=GS A0A1H9BTD1_9ACTN/21-86  AC A0A1H9BTD1.1
#=GS C9ZCP0_STRSW/10-74      AC C9ZCP0.1
#=GS A0A1J4PZG4_9ACTN/6-71   AC A0A1J4PZG4.1
#=GS A0A550HIA6_9ACTN/10-75  AC A0A550HIA6.1
#=GS G2GGW8_9ACTN/10-75      AC G2GGW8.1
#=GS E4N5V2_KITSK/9-74       AC E4N5V2.1
#=GS A0A3R9UBL0_9ACTN/10-75  AC A0A3R9UBL0.1
#=GS A0A0G3AUS9_9ACTN/6-71   AC A0A0G3AUS9.1
#=GS A0A7M2SXE4_9ACTN/10-75  AC A0A7M2SXE4.1
#=GS A0A1S2PI90_9ACTN/10-75  AC A0A1S2PI90.1
#=GS H2K396_STRHJ/6-71       AC H2K396.1
#=GS A0A3G2JRA0_9ACTN/6-71   AC A0A3G2JRA0.1
#=GS A0A086N6L0_9ACTN/10-75  AC A0A086N6L0.1
A0A1H4NJT8_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A505DKI7_9ACTN/10-75             ......IVDNRGTLQVAAADVSKLLRTVGGRWLHLV..EAGHEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7W7U2G9_9ACTN/10-72             ...vpg-----GPLLLPADEVTDLLRRLATCWLDSA..GVEDSGLEPETVEALVDSVTEVADRIDTECIA----lmp.
A0A6B2S7W5_9ACTN/10-75             ....vp--DEQGVLHVAAADVSHMLRTLGAGWLQAV..RDDASNADEDTVAALTIELAKLADQIDVECIAHTS-k...
A0A1V9K579_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1J4NZF9_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLHLV..EAGEDELDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0X3VP21_9ACTN/10-75             ......IVDAHGTLQVAAADVSKLLRTVGGRWLHLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1B1BDK6_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EDGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A514JYB8_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
Q9FCA8_STRCO/6-71                  ......IVDDRGTLQVAASDVSKLLRTVGGRWLRLV..ETGEESLDEDTVAALTIELAKLADRIDVACIAHSSG....
F8JK81_STREN/10-74                 ...awh----DGQLHMPAADVARLLRSIAALWSEWT..AAGEPELDRQTADTLAGTLTDVADQLDLACIAEV--td..
A0A2U2Z6S6_9ACTN/10-75             ......IVDDRGTLQVTAADVSKLLRTVGGRWLRLV..ETGEDRLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1X4I990_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTVGGRWVRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0L0KDN7_9ACTN/10-75             ......IVDDRGDLQVAAADVSKLLRTLGGRWLHLV..EGGESGWDEETVADLTIELAKLADRIDVACIAHSSG....
A0A1V6MNQ6_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLHLV..EAGAEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1X7FD24_9ACTN/21-86             ......IVDDRGTLQVSAADVSKLLRTLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1Q4UYF5_9ACTN/10-75             ......IIDSHGSLHVAAEDVSKLLRGIGGHWLHLV..EHGRRGLDEDTVATLTIELAKLADRIDVACIAHQTA....
A0A2I0SNM7_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0D0PVM4_KITGR/2-67              ..icgl----SGDLAIPAQQVVELLRALPKEWQEWA..DRDDNRLDPVTTAVLADLVRQLADQIDLACIE----iast
A0A101N5S9_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRSLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A6B1PVQ0_9ACTN/6-71              ......IVDDRGALQVAAADVSKLLRTVGARWLHLV..EAGEQRLDEDTVAALTIELAKLADRIDVACIAHSSG....
S5VI16_STRC3/6-70                  ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQ-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7W7XE17_9ACTN/10-71             ...vpg-----GPLLLPADEVTLLLRHLAEHWRESA..EAYDSGLEPETVEALVGALTEVADRIDAECI-----glm.
A0A6H9UYW8_9ACTN/10-75             ......IVDDRGNLQVAASDVSKLLRTVGGRWLHLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A177HK80_9ACTN/10-75             ......IVDRQGALHVAAADVSKLLRTLGGQWLRMV..HAGNEALDEDTVAALTIELAKLADRIDVACIAHSS-s...
D5ZVE8_STRV1/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2P8Q420_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTMGGRWLHLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A117QQZ6_9ACTN/10-74             ......IVDDHGALQVAAADVSKLLRTVGARWVRLV..EAGE-DLDEDTVAALAIELAKLADRIDVACIAHSSG....
A0A6H0CI75_9ACTN/10-75             ......IVDDRGALQVSAADVSKLLRTVGARWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A101CE56_9ACTN/10-75             ......IVDDHGTLQVAAADVSKLLRTLGGRWVRLV..EAGEEGLDEDTVATLTIELAKLADRIDVACIAHSS-r...
A0A7M2TB48_STRCW/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A4Q7X5W0_9ACTN/21-86             ......IVDDRGTLQVSAADVSKLLRTLGGRWLHLV..EAGTEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0L8LKF1_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0M8WN79_9ACTN/24-89             ......IVDDRGTLQVAAADVSKLLRTVGARWLHLV..EAGEQVLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7K2TDL6_9ACTN/10-75             ......IVDHRGTLRVSAADVSKLLRTVGGRWLRLV..EAGDEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2Z4V667_9ACTN/9-74              ...vpa---DDGALLIPADHVTDLLRRLAADWVEPA..DRGATRGDEQTVLDLAGVLTEIADQIDVECIGFASA....
A0A5R9LU34_9ACTN/13-78             ......IRDDDGHLYAPAHEVSALLRRLGASWHEWI..ERGVLDLDAETVDSLADSLTEVADQIDVQCIGHHT-t...
A0A101P796_9ACTN/6-71              ......IVDDRGTLQVAAADVSRLLRTVGARWLRLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
S4MIM9_9ACTN/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EAGESGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2S4YSQ6_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRRLGGRWVRLV..EEGDQGLDEDTVAALAIELAKLADRIDVACIAHSSG....
A0A4Y3VEP0_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A3KKD9_STRA7/10-75                 ......IVDDRGTLQVAASDVSKLLRTVGGRWLRLV..EAGEESLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0M8VJU7_9ACTN/4-68              ......IVDDRGTLQVAASDVSKLLRTVGGRWLHLV..EAGQD-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1K2FUG1_9ACTN/20-85             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGERGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A5Q0LLB0_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLRLV..EAGEGELDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A221NTB1_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2W2MGU8_9ACTN/10-75             ......IVDDCGTLQVAAADVSKLLRTVGGRWLRLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0X3XY64_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0N0SWG3_9ACTN/4-69              ......IVDDQGTLHVAASDVSKLLRTVGGRWLRLV..EAGDEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7W9PQP8_9ACTN/10-75             ......IVDDRGALQVAAADVSKLLRTVGARWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A4P6TQB9_STRSO/10-75             ......IVDERGALRVSAGDVSKLLRSVGARWVHLV..EAGERGLDEDTVAELTIELAKLADRIDVACIAHSSG....
A0A2A2YVJ0_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
Q826P9_STRAW/10-75                 ......IVDDRGTLQVSAADVSKLLRTVGGRWLHLV..EAGQDGLDEDTVATLTIELAKLADRIDVACIAHSSG....
A0A7W7PSL5_9ACTN/10-75             ......IVDDRGALQVAAADVSKLLRTVGGRWLHLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0M8VR89_9ACTN/4-69              ......IVDDRGTLQVAASDVSKLLRTVGGRWLHLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2G9DV14_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLHLV..EAGADDLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2M9IQ42_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQGGLDEDTVAALTIELAKLADRIDVACIAHSSG....
F3NTQ8_9ACTN/6-71                  ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..ESGQGGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A089X7D0_STRGA/1-57              .....m----------AAADVSKLLRMVGGRWLHLV..EAGEEGLDEDTVATLTIELAKLADRIDVACIAHSSG....
A0A0M8QRE3_9ACTN/4-69              ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1H5PQG8_9ACTN/6-71              ......IVDDRGTLQVAAADVSKLLRTLGARWLRLV..EADEGGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A6G4VCA9_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQEGLDEDTVATLTIELAKLADRIDVACIAHSSG....
A0A176L1P5_9ACTN/6-71              ......IVDDRGSLQVAAADVSKLLRTVGGRWLRLV..EAGEQELDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A022M8W9_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTVGGRWLRLV..ETGQERLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A101UCS1_9ACTN/10-75             ......IVDDRGTLQVAAAEVSRLLRTLGGRWLHLV..EAGAEDLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7X1HWD3_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0U3PTF2_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0M9YU68_9ACTN/4-69              ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2U3A696_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1C4LQ89_9ACTN/21-86             ......IVDDRGTLQVTAADVSKLLRTVGARWLHLV..EAGDDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7K2FUH2_9ACTN/10-74             ......IVDDRGALSVSAADVSALLRSVGARWVHLV..EAGER-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2U9NXL4_STRAS/10-75             ......IVDDRGALQVAAADVSKLLRTLGGRWLRLV..ENGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A101T9S0_9ACTN/10-74             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQ-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7K2JHE0_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTVGGRWLRLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1E5PLS8_9ACTN/11-72             ....pg-----GRLLIPADDATSLLRHLAAGWLHAV..YEGEAELDPGTTLALAGVLMELADQIDVECIAF---mp..
A0A250VKZ8_STROL/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQDGLDEDTVATLTIELAKLADRIDVACIAHSSG....
A0A2G5IHQ8_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A124I7N5_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGDDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A101UUN2_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A510TDV1_9ACTN/21-85             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQ-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1Q5KK65_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A117NYZ2_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTVGGRWLHLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
V6JLF7_STRRC/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGARWLRLV..EGGEQRLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2H5B7V1_9ACTN/10-74             sttddh-------LLVPADQVTVLLRRLAADWSEAA..QDGDSGLDQETLLALVAVLTDLADQIDVECIAVA--se..
A0A7Z0PTW9_9ACTN/10-75             ......IVDSGGTLQVAAADVSKLLRAVGGRWLRLV..EDGRDDLDEDTVAALTIELAKLADRIDVACIAHSS-e...
D9VJM2_9ACTN/10-73                 ...vpd-----GGVLIPAGEVTGLLRHLAGEWLYVV..YHGEAPLDPKTTLGLAGVLMAFADQIDVECIAY---lpg.
A0A170WQY1_9ACTN/6-71              ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQGGLDEDTVAALTIELAKLADRIDVACIAHSSG....
K4RF99_STRDJ/21-85                 ......IVDDRGTLQVAAADVSRLLRTVGGRWLHLV..EAGE-DLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1A9BPF7_9ACTN/10-74             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGE-DLDEDTVAALTIELAKLADRIDVACIAHSSG....
D6K5F3_9ACTN/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A5N8XAV8_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EDGEAGLDEETVATLTIELAKLADRIDVACIAHSSG....
A0A2Z5JV04_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EGGESGLDEDTVAELAIELAKLADRIDVACIAHSSG....
A0A5N8V999_9ACTN/10-75             ......IVDDRGTLQVSASDVSKLLRTVGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A081XQM7_STRTO/10-75             ......IVDDRGTLQVAAADVSRLLRTVGGRWVRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2W6QDL8_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTMGGRWLRLV..EAGDQDLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0C5FM99_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1S2QKM8_9ACTN/6-70              ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGEQ-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0Q9A3L0_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTLGGRWLHLV..EAGAEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7K3H1P4_9ACTN/6-71              ......IVDDRGTLQVAASDVSKLLRTVGGRWVRLV..EAGEVSLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2A3HB75_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
M3D8L2_9ACTN/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGGRWVRLV..EAGEGGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A117PTX0_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EDGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0F5W600_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTVGGRWLHLV..EAGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
L1KZ41_9ACTN/10-75                 ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A4Q6IQN9_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLHLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2V4P249_9ACTN/10-74             atpedg-------LLVPAGQLTALLRGLGAEWLRWG..TDPQLGLDQATLQALARILTDLADQVDAECIG----lasr
A0A0B5D7Y3_9ACTN/10-75             ......IVDDHGTLQVAAADVSKLLRTLGGRWLRLV..EAGEDGLDEDTVATLTIELAKLADRIDVACIAHSS-r...
A0A1Q5MTV8_9ACTN/9-74              ...ipa---SDGMLLIPADHVTALLRNLAQDWEHST..DAGEIRADKETALALAGVLAELADQIDVECIGFAS-c...
A0A6B2XF50_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRSLGGRWLHLV..EAGAEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
L7FHC9_9ACTN/10-75                 ......IVDDRGTLQVAASDVSKLLRTVGGRWLHLV..EAGQDDLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0F4IXI7_9ACTN/9-72              ...sva----DGGLLIPADEVTALLRRLAGGWLHSV..YDGETDLDPGTTLGLANVLVELADQIDVECIG----fmp.
A0A7G1PAC7_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTMGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A6B3AT56_9ACTN/10-75             ......IVDDSGTLQVAAADVSKLLRTVGGRWLRLV..ESGEQKLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0N0NC21_9ACTN/21-86             ......IVDDRGTLQVSAADVSKLLRTLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A2S4Y796_9ACTN/10-75             ......IVDDRGVLQVSAADVSKLLRTVGTRWVRLV..EAGESGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A3Q8VGG7_9ACTN/10-75             ......IVDDRGTLQVAAADVSRLLRTVGGRWVRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
D9VLZ2_9ACTN/11-74                 .....a---DDGGLLIPADHVTALLRQLAEDWLHAT..ETGEMPADEETVSELADVLTELADQIDVECIGC---ase.
A0A6N7KYV8_9ACTN/10-76             ..fphs-----GGVLIPAAEVTTMLRRVAISWVDLAddEDGATDFDPETVRALAGALGRLADQIDVECIAFAS-d...
A0A1A5NVG0_9ACTN/10-75             ......IVDHRGTLQVSAADVSKLLRTMGGRWLHLV..ESGDDRLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A4R1DL86_9ACTN/10-75             ......IVDNRGTLQVAAADVSKLLRTVGGRWLHLV..EAGEDGLDEETVATLTIELAKLADRIDVACIAHSSG....
A0A1D2ILR3_9ACTN/10-75             ......IVDHRGTLQVSAADVSKLLRTVGGRWLHLV..ESGDDRLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A426ULS4_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRSLGGRWLHLV..EAGSEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A5N8W6A3_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLYLV..EAGQGGLDEETVATLTIELAKLADRIDVACIAHSSG....
A0A7K2KTE5_9ACTN/8-73              vsasdd------RLLVPAERVTALLRGVAAGWLGAA..ERGESDLDPRTTLTLARSLSDLADQIDVECIAF---mpa.
A0A3M0I410_9ACTN/10-75             ......IVDDRGALRVAAADVSKLLRTVGGRWVRLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1H9BTD1_9ACTN/21-86             ......IVDDRGALQVSAADVSKLLRTLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
C9ZCP0_STRSW/10-74                 ......IVDDRGTLQVSAAEVSKLLRTVGGRWLHLV..EAGEE-LDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1J4PZG4_9ACTN/6-71              ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..ETGEPRLDEHTVAELTIELAKLADRIDVACIAHSSG....
A0A550HIA6_9ACTN/10-75             ......IVDDRGTLQVSAADVSKLLRTMGGRWLHLV..EAGQDGLDEDTVAALTIELAKLADRIDVACIAHSSG....
G2GGW8_9ACTN/10-75                 ......IVDDRGTLQVAASDVSKLLRTLGGRWLHLV..EAGADGLDEDTVAALTIELAKLADRIDVACIAHSSG....
E4N5V2_KITSK/9-74                  ..icgl----SGGLAIPALQVVELLRALPEEWQEWA..DCEGSGLDPATTGTLADLVRQLADRIDLACIE----iase
A0A3R9UBL0_9ACTN/10-75             ......IVDNRGELQVAAADVSKLLRTVGGRWLRLV..EAGQEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A0G3AUS9_9ACTN/6-71              ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A7M2SXE4_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWVHLV..ENGEEGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A1S2PI90_9ACTN/10-75             ......IVDDRGTLQVAAADVSKLLRTVGGRWLRLV..EAGEDGLDEDTVAALTIELAKLADRIDVACIAHSS-l...
H2K396_STRHJ/6-71                  ......IVDDRGTLQVAAVDVSKLLRTVGARWLHLV..EAGEQGLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A3G2JRA0_9ACTN/6-71              ......IVDDRGTLQVAAADVSKLLRTVGARWLHLV..DAGEQPLDEDTVAALTIELAKLADRIDVACIAHSSG....
A0A086N6L0_9ACTN/10-75             ......IVDDRGTLQVAASDVSKLLRTVGGRWLRLV..EAGEESLDEDTVAALTIELAKLADRIDVACIAHSSG....
#=GC seq_cons                      ......IVDDRGTLQVAAADVSKLLRTVGGRWL+LV..EAG-pGLDEDTVAALTIELAKLADRIDVACIAHSSG....
//