#=GF ID   DUF6255
#=GF AC   PF19768.3
#=GF DE   Family of unknown function (DUF6255)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   25.60 25.90;
#=GF NC   23.50 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   29349495
#=GF RT   Genomic-driven discovery of an amidinohydrolase involved in the
#=GF RT   biosynthesis of mediomycin A.
#=GF RA   Sun F, Xu S, Jiang F, Liu W;
#=GF RL   Appl Microbiol Biotechnol. 2018;102:2225-2234.
#=GF DR   INTERPRO; IPR046222;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001662) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, polyketide. It includes a
#=GF CC   member from the mediomycin A biosynthetic gene cluster from
#=GF CC   Kitasatospora  mediocidica [1]. 
#=GF SQ   18
#=GS A0A3S9PGA9_STRLT/11-82  AC A0A3S9PGA9.1
#=GS M3A8H5_STRMB/1-62       AC M3A8H5.1
#=GS A0A3B0BUJ0_9ACTN/8-60   AC A0A3B0BUJ0.1
#=GS M3C205_STRMB/16-84      AC M3C205.1
#=GS A0A7W7LSE7_9ACTN/7-75   AC A0A7W7LSE7.1
#=GS A0A3S9PLB7_STRLT/2-72   AC A0A3S9PLB7.1
#=GS A0A0K9XFL8_9ACTN/1-68   AC A0A0K9XFL8.1
#=GS A0A2G1XDH0_STRCJ/1-68   AC A0A2G1XDH0.1
#=GS A0A7W7PJZ0_9ACTN/10-78  AC A0A7W7PJZ0.1
#=GS A0A7W7LMI5_9ACTN/4-56   AC A0A7W7LMI5.1
#=GS M2ZVL0_STRMB/7-76       AC M2ZVL0.1
#=GS A0A0K9XGX4_9ACTN/8-75   AC A0A0K9XGX4.1
#=GS M3C0R6_STRMB/9-77       AC M3C0R6.1
#=GS A0A0K9XKG8_9ACTN/7-75   AC A0A0K9XKG8.1
#=GS A0A7W7PJ67_9ACTN/15-85  AC A0A7W7PJ67.1
#=GS A0A7W7LLT6_9ACTN/1-59   AC A0A7W7LLT6.1
#=GS A0A7Y7B9C5_STRMO/1-68   AC A0A7Y7B9C5.1
#=GS A0A445NAA6_STRNE/8-56   AC A0A445NAA6.1
A0A3S9PGA9_STRLT/11-82             .p-ARHCPHPAgSWTAA.GGLATCTHCGTRRVLDFRPLAQAlELPGRMA.LYAPT.TSGRG----------------hargvvpyrrrellrr..........
M3A8H5_STRMB/1-62                  ..MKVPCRHPAdGWTAD.RGVLTCDGCGVRRIEDYTALGPA.VEPPDFG.-PSPH.--------GPVITAQGVLRFR..........................
A0A3B0BUJ0_9ACTN/8-60              ..LMARCTHAG.GWTRE.GDAARCDHCGTRRFMGYAALLVP.ELPQWAA.C----.---------------------lplsgsts..................
M3C205_STRMB/16-84                 .l-VRNCAHRE.GWSAApDGVRRCVSCGVERYGAYGPLRLP.KERNPLTaKTGT-.--ERAAAAATAIAALG-----trfle.....................
A0A7W7LSE7_9ACTN/7-75              .l-VDNCPHLS.GWDTA.DGEERCRSCGTRRFTRYGALRPP.GLPAALT.-PRPR.NATQADRSATIAISRACRRL-g.........................
A0A3S9PLB7_STRLT/2-72              .a-AMRCAHRA.GWAQR.GGEARCHDCGVRRFTSYGALRPP.GLAAAVA.TPRTFlVGHQADRAAALNLTRRARYA-g.........................
A0A0K9XFL8_9ACTN/1-68              ..-MQHCTHRS.GWEQG.DGEIRCRDCGARRFTGYAALRTP.ELPVAAG.-PPPR.DPGRADRTAAAIIALGPHNL-s.........................
A0A2G1XDH0_STRCJ/1-68              ..-MKNCRHRF.LQDAA.PGEHRCAGCGMRRFTSYGALRPP.GLPEPRV.--RPEvAAEKADRRASLVIALGLY---rnr.......................
A0A7W7PJZ0_9ACTN/10-78             tn--AHCAHPAaAWATA.GGIHTCTACGTQRFADYRGLALAlPLPERPG.-PGPT.-RQGPSRAALLAKV-------reanlr....................
A0A7W7LMI5_9ACTN/4-56              .r--AKCAHPAtGWTVT.RGIATCTACGVRRFHHYGALW--.-------.-----.---------------------rdngeyvrgrgrkqtada........
M2ZVL0_STRMB/7-76                  .l-IRHCGHRS.GWERA.AGEERCRDCGARRFTDYAALLMP.ERPVAAA.TPPPR.DPTRADRAAAALIAHGLHRLS..........................
A0A0K9XGX4_9ACTN/8-75              ..LMDNCQHRE.GWETA.NGEERCTRCGTRRFTEYGALRPP.EVPQGVA.--PPE.GRGRADRSVGAAVARTVRQIR..........................
M3C0R6_STRMB/9-77                  .p-PLKCPHPAaGWTAA.DGMRTCGACGTRRVDDYRALALAlELPQPTQ.LFGPT.---ARCRGAMTVAPYDPASAR..........................
A0A0K9XKG8_9ACTN/7-75              ..LMSHCQHLS.GWESA.HGEDRCPTCGTRRFTDYGALRPK.ELPPAVT.-PSPH.DRIRADRAAATVIARTVRHLS..........................
A0A7W7PJ67_9ACTN/15-85             sa--ARCAHRS.GWTHA.TGESHCNCCGTRRFTQYGALRPP.GLPQAVA.-TADR.DPRAADRSAALNVALASR---rgarr.....................
A0A7W7LLT6_9ACTN/1-59              ..---------.-----.--MKTCRGCGTHRFIDYRPLALAlPLPEGP-.--HPH.GP-------------------tvthaglmprqrnagqlpsallakvr
A0A7Y7B9C5_STRMO/1-68              ..-MVNCQHNA.AWRHA.NGVSQCTRCGARRFTDYGALRPD.GLPQPAR.TRRQL.-LVERDKAAALIIAKGHYRV-s.........................
A0A445NAA6_STRNE/8-56              vv--SACAHHA.EWTRT.VDKATCKKCGVERYSSYRLLRMS.VE-----.-----.---------------------qswfphrhrr................
#=GC seq_cons                      ...htpCsHhu.GWspA.sG.ppCssCGsRRFscYuALt.s.tLPtsss...tPp....tss+sAshhhshs.h...t.........................
//