#=GF ID DUF6300
#=GF AC PF19817.3
#=GF DE Family of unknown function (DUF6300)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 27.80 27.80;
#=GF TC 30.40 30.20;
#=GF NC 26.30 26.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 30867595
#=GF RT Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of
#=GF RT natural products.
#=GF RA Zhang B, Wang KB, Wang W, Wang X, Liu F, Zhu J, Shi J, Li LY,
#=GF RA Han H, Xu K, Qiao HY, Zhang X, Jiao RH, Houk KN, Liang Y, Tan
#=GF RA RX, Ge HM;
#=GF RL Nature. 2019;568:122-126.
#=GF DR INTERPRO; IPR046267;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0002024) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, polyketide, in particular,
#=GF CC the nargenicin biosynthetic gene cluster from Nocardia
#=GF CC argentinensis [1]. This family appears to be predominantly found
#=GF CC in bacteria and unclassified phages.
#=GF SQ 60
#=GS I4AZP5_9CAUD/1-82 AC I4AZP5.1
#=GS A0A0A8ECT3_9ACTN/10-119 AC A0A0A8ECT3.1
#=GS A0A101CF44_9ACTN/2-64 AC A0A101CF44.1
#=GS A0A5D0Q804_9ACTN/3-106 AC A0A5D0Q804.1
#=GS A0A5C8JE16_9ACTN/1-95 AC A0A5C8JE16.1
#=GS A0A2W2FC08_9ACTN/6-115 AC A0A2W2FC08.1
#=GS A0A545AM47_9ACTN/15-85 AC A0A545AM47.1
#=GS A0A840NK65_9PSEU/2-87 AC A0A840NK65.1
#=GS A0A6G9YB26_9NOCA/4-101 AC A0A6G9YB26.1
#=GS A0A8J3HHE4_9ACTN/3-105 AC A0A8J3HHE4.1
#=GS A0A841BZR2_9ACTN/4-106 AC A0A841BZR2.1
#=GS A0A8J3VK16_9ACTN/4-100 AC A0A8J3VK16.1
#=GS Q82YG8_STRAW/2-97 AC Q82YG8.1
#=GS A0A426U9J1_9ACTN/37-122 AC A0A426U9J1.1
#=GS A0A810P1W2_9ACTN/3-105 AC A0A810P1W2.1
#=GS A0A646KKF4_STRJU/4-92 AC A0A646KKF4.1
#=GS A0A1G8IIU4_9ACTN/2-106 AC A0A1G8IIU4.1
#=GS A0A2R4TCD3_9ACTN/2-94 AC A0A2R4TCD3.1
#=GS A0A3E2YI75_9ACTN/1-106 AC A0A3E2YI75.1
#=GS A0A543CHX0_9ACTN/8-115 AC A0A543CHX0.1
#=GS A0A239PFU0_9ACTN/2-104 AC A0A239PFU0.1
#=GS G2GP90_9ACTN/2-97 AC G2GP90.1
#=GS A0A8J8H5H8_9ACTN/2-99 AC A0A8J8H5H8.1
#=GS A0A7W7WCK8_9ACTN/1-90 AC A0A7W7WCK8.1
#=GS A0A7W9GC99_9ACTN/2-106 AC A0A7W9GC99.1
#=GS A0A3A4BJN4_9ACTN/1-106 AC A0A3A4BJN4.1
#=GS A0A221W8J3_9PSEU/4-118 AC A0A221W8J3.1
#=GS A0A1H6BZC6_9ACTN/5-113 AC A0A1H6BZC6.1
#=GS A0A1S2K8G3_9ACTN/4-95 AC A0A1S2K8G3.1
#=GS A0A542PY03_9ACTN/2-94 AC A0A542PY03.1
#=GS A0A7Y5XBP7_9ACTN/4-103 AC A0A7Y5XBP7.1
#=GS A0A840PX75_9PSEU/1-87 AC A0A840PX75.1
#=GS A0A1H6EUY1_9ACTN/3-80 AC A0A1H6EUY1.1
#=GS Q82QP4_STRAW/11-103 AC Q82QP4.1
#=GS A0A1H7YJL8_9ACTN/3-106 AC A0A1H7YJL8.1
#=GS A0A318JNU6_9NOCA/5-111 AC A0A318JNU6.1
#=GS A0A4U0SAL4_9ACTN/39-126 AC A0A4U0SAL4.1
#=GS A0A1U9ZVX5_9ACTN/3-106 AC A0A1U9ZVX5.1
#=GS A0A1J4Q4Z4_9ACTN/11-119 AC A0A1J4Q4Z4.1
#=GS A0A2M9JP08_9ACTN/9-117 AC A0A2M9JP08.1
#=GS A0A086MUS6_9ACTN/6-115 AC A0A086MUS6.1
#=GS Q9ACS9_STRCO/6-116 AC Q9ACS9.1
#=GS A0A2S6H0W4_9PSEU/6-94 AC A0A2S6H0W4.1
#=GS A0A059VZ17_STRA9/1-110 AC A0A059VZ17.1
#=GS A0A4R4NTT0_9ACTN/1-99 AC A0A4R4NTT0.1
#=GS A0A1E5NYA3_9ACTN/30-116 AC A0A1E5NYA3.1
#=GS A0A0M8YML2_9ACTN/1-64 AC A0A0M8YML2.1
#=GS A0A0M9YXJ7_9ACTN/37-123 AC A0A0M9YXJ7.1
#=GS A0A8J3LBQ3_9ACTN/3-105 AC A0A8J3LBQ3.1
#=GS A0A0C1XTQ0_9ACTN/2-94 AC A0A0C1XTQ0.1
#=GS A0A1S2NVI8_9ACTN/10-118 AC A0A1S2NVI8.1
#=GS A0A1G9KWD6_9ACTN/6-111 AC A0A1G9KWD6.1
#=GS A0A5S4FD69_9ACTN/1-106 AC A0A5S4FD69.1
#=GS A0A1E5P140_9ACTN/37-120 AC A0A1E5P140.1
#=GS A0A4R4N4Z4_9ACTN/2-109 AC A0A4R4N4Z4.1
#=GS A0A841C0I2_9ACTN/4-106 AC A0A841C0I2.1
#=GS W7IWB7_9PSEU/10-106 AC W7IWB7.1
#=GS A0A7W5VLC7_9ACTN/7-116 AC A0A7W5VLC7.1
#=GS A0A2W2F5P9_9ACTN/2-106 AC A0A2W2F5P9.1
#=GS A0A2A2Z6R7_9ACTN/4-97 AC A0A2A2Z6R7.1
I4AZP5_9CAUD/1-82 .......mals----------..------.-------.---------DGG....TVRGYRTVVLCPDCDR...DNPN..ASGVLAFFAMHERIDPG.TVQEAAPLIEEWVQRSAGEVYT.DD.....E..L..AEDIRLWRSGD-m..................
A0A0A8ECT3_9ACTN/10-119 ..........l-VDVRTAALP..PCQRCG.AAVLLSA.RYRHSWENQAGA....AVTGFKETALCPTCDA...DDPA..AAGLLALRGQVRHLDAA.HLTALGELVPAWLEAIRQRTPD.PA.....E..L..AAEEALWRAGE-l..................
A0A101CF44_9ACTN/2-64 .........pi----------..------.-------.------------....------HLDLCTFCDAgdaRRPA..AGILVQFFADGGGHDES.RSQEAAQLLTAWTRE-------.--.....-..-..AMAAHGWYWHE-k..................
A0A5D0Q804_9ACTN/3-106 ......alpgg--------AP..ACPRCRtGEILAVL.RLPRTWTNASGR....PVRGLGEVLLCARCDA...GDP-..---LVTYFAVHGTARPE.HAALLSRLLREWLARARPGTPD.EN.....A..L..RAEADVWRRGD-l..................
A0A5C8JE16_9ACTN/1-95 ..........m--------TP..ACPRCRtGDVLAVL.RLPHIWTNASGN....EVRGISEVLLCARCDA...GDP-..---LVASF-----TPPY.DPDRFVRALLGKAAGARPPEPD.EH.....A..L..RAEAEAWYRGE-l..................
A0A2W2FC08_9ACTN/6-115 .........id--IVSGQEPP..TCPRCR.QEGLLLA.RVPYGWTNEGGV....AVEGRNGVVLCAACDT...DTPY..AAQLITWFHVHGTVEAG.HSEEFLRLLAEWAEQISVPPLD.RQ.....R..L..ETEIEQWRRGR-a..................
A0A545AM47_9ACTN/15-85 .........ve----------..------.-------.------------....------SAVLCAGCDL...DHPT..GGPIVLWFAVNGQIDTTaQLDEVAALVRRWVDGLE-----.--.....-..L..EASVDAW-----maqlaapaaaga.......
A0A840NK65_9PSEU/2-87 .....ptrnte----------..------.-------.-----------H....SVPQYATVTLCPNCDR...HHPApeVQGVIAYFTLNEHISTD.EIEGAGQVLSDWARYVAAHPPV.YNs...dN..L..DEDIEAWARGE-m..................
A0A6G9YB26_9NOCA/4-101 ...eisvvddl----------..PCHRCG.DTLICAV.RVPHSFLREDGV....EVRGMRTVGLCPNCAG...DNPA..ARAVVDHFRTGSRLPDI.-----AVPLGEWLSEVLPAQVD.DA.....Q..L..AA----------lragg..............
A0A8J3HHE4_9ACTN/3-105 ...avevraag--------DA..RCGSCT.ERLYLTA.KIPVPQSRRSRV....-------VHLCPGCDA...GLPE..AQGLLAYFAEHRQVRPE.DMHRVSELVGRWLEALTRPDPQ.QS.....S..L..AADVAAWWSG--rg.................
A0A841BZR2_9ACTN/4-106 .....vdlmgg------AQLP..PCHRCT.SELYLTA.RTPH------PT....-MPGSRIVGLCPRCDA...RDPH..AQPLLAYLAIHDGVQPG.DERTVAALLHDWTVTAATRIPD.PA.....A..F..DDDLHTWSAGD-l..................
A0A8J3VK16_9ACTN/4-100 .vevrvasdtr----------..-CPRCA.ARLCLTA.S-----------....-IGGKRTVALCPSCDS...ADPH..AERLIGYFAAHGSVQPQ.DMSHVSELLGHWLGSLDGRDDP.EP.....T..L..AAQVEAWWA---trp................
Q82YG8_STRAW/2-97 .........el--LRFSDRLP..QCSRCR.GDLIMSG.VAPQNDKHGRPI....------HLELCPVCDTgdvDRPA..AGLLVQWFADRGGHDES.RVQEGSHLLMEWTRE-------.--.....-..-..CMAVHGWYLQD-t..................
A0A426U9J1_9ACTN/37-122 ......rpvas-----DEEQParPCSRCG.GDLLLHW.HGPL----MTGV....------WMELCPACDA...HRPA..ARAFIGWHHDADRD---.-PAALPQLFEDWETE-------.--.....-..-..TMHARGW-----traa...............
A0A810P1W2_9ACTN/3-105 .....dvkvva------AAGT..RCGTCA.EALYLTA.QVPQPRSSRT--....-----RTVGLCPQCDA...GRPE..TQGLLAYFAEHQRVRPE.DLHQVHELVGRWLEALTERADR.DG.....S..L..AADVEAWWAA--ra.................
A0A646KKF4_STRJU/4-92 ..........y-RIARENELP..PCSRCG.GEIIIGA.DGPV---DGVPV....------RLELCPVCDT...DAPA..GGRLIAFLDAGGGRDAS.RVEEATRLMWAWQRE-------.--.....-..-..AMAAH-------gfhwvp.............
A0A1G8IIU4_9ACTN/2-106 ........sga---------Q..TCPRCRtGDILAIL.RLPHTWENATGK....RVSVRSDLLLCSHCDA...HDPL..TGPIVTYFALHETVRPE.HMHHLARLLRRWIDHASIPKPN.EK.....P..L..TTEAEAWYRGD-l..................
A0A2R4TCD3_9ACTN/2-94 .........dr--VELAETLP..SCSRCG.GSLTTSG.VMPHEDASGFPI....------HLELCSSCDT...DKPA..AGALLRWFATGGGHDMA.RVHEGADLMTEWTKE-------.--.....-..-..AMAEQGWIWSD-h..................
A0A3E2YI75_9ACTN/1-106 ......mtrdl----------..PCHRCG.TDNVLAVlRLPGTCTNASGN....RYPVVHELHLCVRCDA...DNPL..AGPVVGYLTADEARQTE.NVAQLARDLLRWIDQARPARPD.ED.....A..L..EAEVDAWYRGE-l..................
A0A543CHX0_9ACTN/8-115 ....alvtgpv---------R..ACPVCG.GEILAAL.QVPNGWTTEGGK....QVRGTSEVLLCERCDR...DDPV..TGPIVVFFTVHEQATAD.QADELAALLQRWADHAVARRPD.LQ.....A..L..DAEVDAWYRGE-l..................
A0A239PFU0_9ACTN/2-104 ....taiasng---------N..RCPVCD.TEIILAA.DRPH---PRFPA....---AMYRQHLCPVCHR...DDPA..ASGLLAFFAVHPMIELS.TSSTFAALFQEWLDRVPDPPMVsDE.....D..F..DADVEAWHRGD-f..................
G2GP90_9ACTN/2-97 ........all---EFSDRLP..QCSRCR.GSLIMSG.VAPQDDKHGRPI....------HLELCPVCDTgdvDRPA..AGLLVQWFADGGSHDES.RIKEGSHLLMEWTKE-------.--.....-..-..CMAIHGWYLQD-a..................
A0A8J8H5H8_9ACTN/2-99 ....qvsvagg----------..RCDLCG.ERLCLTA.RITS-----AGR....------SVGLCPRCDA...DNPH..GAELIAYFATRSAVAAQ.DRATIADLLGRWLGSLDQDRVT.AA.....ApsL..AEAAEAW-----wslyq..............
A0A7W7WCK8_9ACTN/1-90 ..........m----------..------.-----SA.LVSHGWTNASGA....DVRGWVTVVLCADCDA...DAPH..AAPLITWFHVHGSVDAD.NDAAFLALLTEWAKNVRVATLD.EA.....T..L..EEEITAWRRGE-l..................
A0A7W9GC99_9ACTN/2-106 .......tgdr----------..PCPRCR.ADSVLAVlRLPHTWTNAAGN....EVRGVSEVLLCARCDA...GDPA..AGPIVTYFTVYGSVRPE.HATQVARGLRHWAERARPPRPD.EN.....A..L..ADETEAWYRGE-l..................
A0A3A4BJN4_9ACTN/1-106 ........mna--------PA..ACPRCGtGEVLATL.RLPYTWRNASGH....PVRGTSEIVLCARCGA...ADPL..TGPIVAYFARHGTAGAG.DLTSLARALRRWAAGASPPRPD.PG.....A..V..AAEAEAWRRGD-l..................
A0A221W8J3_9PSEU/4-118 ......gvevd------PTRD..TCHRCG.GPLLLSV.RIPHSITGRGGGgerfEVRGRRTVPLCARCDR...DDPG..AMGVIAFFTVHETISDE.TVQAAAPVLRQWIDEAVANPPV.YT.....D..AdlDAEIDAWEAGET...................
A0A1H6BZC6_9ACTN/5-113 ..........i-EVVTEAAPP..DCPRCG.GASLLWA.RVPHGWENATGG....RVEGYSGVVLCGSCDA...DRPH..AAALITWFHVHGRADDT.D-EEFVRLLVAWTAGVVIPALD.ER.....A..L..KDEVERWTLGE-r..................
A0A1S2K8G3_9ACTN/4-95 .........vs--VRRSNDLP..ACSRCN.GPLILAA.QMPQLDASGNPI....------TLELCAACDA...GDTA..AGVLVRFFTSGAANDTS.RAHEGAELLLAFQKEIMAA---.--.....-..-..------------hgyvlvd............
A0A542PY03_9ACTN/2-94 .........tq--VELAERLP..SCSRCG.GPLITSA.VMPQEDADGFPI....------HLELCSSCDT...EKPA..AGALLRWFATGGGHDMS.RVQEGADLLMDWTKE-------.--.....-..-..GMAEHGWCW---say................
A0A7Y5XBP7_9ACTN/4-103 ..vqvsvaggr----------..TCPRCG.AGLCLTA.RIGS----AAPR....-----RTVALCPRCDV...GNPD..AKRLIDYFAGSQTVAAQ.DRAHVSELLGRWLGSLDDQAVA.RP.....S..L..AEAAEAWWAA--rq.................
A0A840PX75_9PSEU/1-87 mpvrdtehtap----------..------.-------.-----------H....----RVTATVCPNCDR...HHPApeVQGVSAYFTLNERITDD.EIEGAAQVLSDWARYVAAHPPT.YTt...dD..L..DDEIKAWERGE-m..................
A0A1H6EUY1_9ACTN/3-80 .......gdgg----------..-CPRCR.TDSVLAVlRLPATWANQAGG....----AREVVLCARCDA...GDP-..---VVAYFAAHGTVRPE.GVDELARLLLDWIDRAR-----.--.....-..-..------------plg................
Q82QP4_STRAW/11-103 ..........y-RLETSGLLP..QCSRCG.GDLIVSV.VAPKNDTDGRPI....------QLQLCSACDA...EKPA..AGALLFWFASGGGHDTE.RSEEGARLLMEWTGE-------.--.....-..-..AMAEYGWYW---pgt................
A0A1H7YJL8_9ACTN/3-106 ........rgg----------..TCPRCRtGEVLAVL.RLPRSWTNTSGS....LVRGTRDVLLCAACDA...DDPL..AGPVVTYFAVHGRARPQ.DAALLAACLLRWIAGARPAEPD.ER.....A..L..RAEAEAWRRGD-l..................
A0A318JNU6_9NOCA/5-111 ...eisyvddl----------..PCHRCA.ATLVCAM.RVPHSFVRADGF....EVRGVRTVGLCPMCDN...ENPA..VRAIFEHIARHGEPDRA.AMLELAALVGEAAMRGLPEALD.EE.....L..L..RAAAAEF-----vrtt...............
A0A4U0SAL4_9ACTN/39-126 ........rpd---RRDRPLP..PCSRCG.MGLVLGW.HGPL----FSGV....------WMELCPVCDA...DGLA..ARALARWI----RNPER.DVRQLPQLFEDWETEVMQAK--.--.....-..-..------------gwvrslpesa.........
A0A1U9ZVX5_9ACTN/3-106 ......gspac--------PP..ACPRCRfGEILAVL.RLPRTWTNASGR....PVRGLGEVLLCARCDA...GDP-..---LVTYFAVHATARPE.HAALLARLLRQWAARARPEGPD.ED.....A..L..RAEAEAWRRGE-l..................
A0A1J4Q4Z4_9ACTN/11-119 .......ihlr-----VGATP..PCTRCE.GPTVLQV.RFPYSWTSGNGN....ILKGLRESTLCPVCDQ...ERTE..AEALSGLLTSRHEPDTA.GLAPFVGMVAAWVESLRQERVD.LD.....L..L..ATEHERWQRGD-l..................
A0A2M9JP08_9ACTN/9-117 .........dv--IIQLDDMD..ACRACG.EQSVLKA.SFTQTWTNKRGE....AMSGLCEAVLCPECER...GTPA..ADELLALFAVDETLGIN.NIETFGGLVAAWVESVRHQRVD.EA.....R..L..TEEHEQWS----gel................
A0A086MUS6_9ACTN/6-115 ........eia---VRVEEVP..PCARCG.GAALLRV.RFGHSWTNISGH....SVEGFREADLCPACDS...GDGS..ADDLLALLTVAEETPVL.SVADFGGHVVAWVEAVRQRGVD.IS.....R..L..RSEEHAHRL---hge................
Q9ACS9_STRCO/6-116 .........ei--NFRFDQVP..PCARCG.GEALLRV.RFGHSWTNITGH....LVEGFREADLCPACDS...GTTP..ADDLLALFAVAERVPPT.HLAEFGCRVVAWVESVRQPRVD.MV.....R..L..RGEEDAHR----hngel..............
A0A2S6H0W4_9PSEU/6-94 ...evdlvsdl----------..TCHRCA.GELVCAA.RVPHSFARADGH....RVTGSRTVGLCPRCDR...DSPA..AAAVIAYFTAHGTARAD.TVGDLAVALRAWLTQ-------.--.....-..-..------------stve...............
A0A059VZ17_STRA9/1-110 ........mnp---TADPAAP..SCPRCR.TPVLLVV.RHPHTWHNRSGA....PVHGLRESVLCPSCAP...DAPT..AAALLALLGDGDGPPPD.PPASLGPHLYAWLAAVRARTPC.AA.....A..L..ADEESRWRAGE-l..................
A0A4R4NTT0_9ACTN/1-99 ..........m----------..-CPRCR.GEALLWA.RVPYGWTNREGG....RVEGRSGVVLCPACDA...RAPG..AAALITWFHVHGRADDE.D-EEFVRLLVRWATGVSVPPLD.EH.....A..P..EAENERWQRGD-l..................
A0A1E5NYA3_9ACTN/30-116 .........yp--DRDEDEQParPCSRCE.GELLLHW.HGPL----ITGV....------WMELCPACDT...RRPA..ARAFLQWH----RDPDR.DPKALPKLFEDWETE-------.--.....-..-..TMHAHGWARA--pq.................
A0A0M8YML2_9ACTN/1-64 .........ml----------..------.-------.------------....-------LELRPACDA...RRPA..ARALIHWHRDTD----R.APEALPQIFEDWETEAL-----.--.....-..-..------------hvrgwvrapqpeaqsgpaa
A0A0M9YXJ7_9ACTN/37-123 ........hpe---RDEDEQPdrPCSRCG.GALLLHW.HGPL----MTGV....------WMELCPACDA...RRPA..ARAFIQWHR----DADR.DPKALPQLFEDWETE-------.--.....-..-..TMHAHGWARA--pq.................
A0A8J3LBQ3_9ACTN/3-105 ..dvkvraagg---------T..RCGSCA.EALCLTA.QVPLPRSTR---....----TRTVGLCPRCDA...GRPE..TQGLLAYFAEHPQVRPE.DLHRVSELVGRWLEALTERAER.DS.....S..L..AADVEAWWAGR-t..................
A0A0C1XTQ0_9ACTN/2-94 ..........t-RVELSDSLP..PCSRCG.GGLISSI.VMPQEDAAGRPI....------HLELCSLCDT...DKPA..AAALLRWFATGGGKDMS.RVAEGAELLVEWQKE-------.--.....-..-..GMAAHGWEFQ--tg.................
A0A1S2NVI8_9ACTN/10-118 ........eal---LKLEDTP..SCPHCG.GPTLLLA.RYPQAWKSARGE....DVSGIKEAVLCAACDH...VDAA..AAELIALFNLDEQVSPE.-METFGGLAAAWVESVRQRTVD.ET.....L..L..QEQHELWRCGE-l..................
A0A1G9KWD6_9ACTN/6-111 ........iei---VSGPEPP..RCPRCR.REGLLLA.RVPYGWTNAGGV....AVRGRGEVVLCAACDA...DAAR..AAPLITWFHVHATVEPA.DSEEFLQLLAAWADEVSVPPLD.RK.....R..W..EDEIEQ------lt.................
A0A5S4FD69_9ACTN/1-106 ........msv--------AP..ACPRCRaGEVLAVL.RLPHTWANASGG....PVRGMSEIVVCARCDA...GDPL..TGPIVAYFAAHDQVRPE.SLDQLARPLRRWLDRARPPEPD.EQ.....A..L..EAEIEAWYRGD-l..................
A0A1E5P140_9ACTN/37-120 ......dpgdr------DERPkrSCSRCS.RDLLLRW.HGPL----ITGE....------WMELCSACDA...DRPA..ARAFIRWH----LDPER.TVEKLPQLFEDWETE-------.--.....-..-..TMQAKGW-----vrv................
A0A4R4N4Z4_9ACTN/2-109 ....spvtpga----------..ACPRCRtGEVLAVV.RVPHGWTNASGR....PVRGVGEVLLCGRCDA...GRPV..TGPLVAYLTAHESVGSA.ELNDLAPLLRRWMDGVRAPAPD.ER.....A..L..RAETEAWRRGD-l..................
A0A841C0I2_9ACTN/4-106 ...vqvtvagn---------R..RCPRCA.AKLCLTA.TIDQ-----TGR....------AVALCPTCDA...GNAD..AQRLLEYFTTNQTVLPQ.DRALVSEMLGRWLGSATRHEPA.ATltervT..L..ADEAEAWWAA--rq.................
W7IWB7_9PSEU/10-106 ....vdlvagl----------..RCHRCT.GEVVCAV.RVPHSFLRADGT....EVGGTRLVALCPDCDR...GRAG..AAPVIAYFRAHGRVVAD.RVEELAGLLREWVADVGPAR--.--.....-..-..------------agdlehsa...........
A0A7W5VLC7_9ACTN/7-116 .........vd--IISSDRTP..PCPRCG.QEGLLQA.RVPHGWVNASGA....LVQGRNGVVLCATCDA...DQPH..AAALITWFHVNGQVEVG.AEHEFKRLLVAWAEHVHVPLLD.ER.....A..L..TEEAALWQEGE-l..................
A0A2W2F5P9_9ACTN/2-106 .......srev----------..RCPRCRtGDVLAVL.RLPHTWTNASGN....RVRGLGEVLLCAHCDA...ADPL..TGPIVAYFAVNRSVRRQ.DVTTLARLLRHWIDHARPPRPD.MP.....A..L..DAESDAWHRGE-l..................
A0A2A2Z6R7_9ACTN/4-97 ........agr----DEDERP.rPCFRCG.GDLLLEW.NGPW----GTGV....------WMELCPACDA...DRPA..AGAFIAWHRDPDRDPDR.DPKVLPRLFEDWEAE-------.--.....-..-..IMHAHGWTRAE-qpqapa.............
#=GC seq_cons .........sh.........s..sCsRCt.upllhss.+hPps.tstsGt........htpltLCssCDu...ccPs..AssLlsaFsspspsssp.chpphupLLtcWhppht....s..t.....t..l..stchcuWhhu..h..................
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