#=GF ID   DUF6342
#=GF AC   PF19869.3
#=GF DE   Family of unknown function (DUF6342)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   25.60 101.60;
#=GF NC   23.30 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   30705269
#=GF RT   The antimicrobial potential of Streptomyces from insect
#=GF RT   microbiomes.
#=GF RA   Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns
#=GF RA   KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn
#=GF RA   HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR,
#=GF RA   Muller L, Melo WGP, Pinto-Tomas AA, Schmitz A, Wendt-Pienkowski
#=GF RA   E, Wildman S, Zhao M, Zhang F, Bugni TS, Andes DR, Pupo MT,
#=GF RA   Currie CR;
#=GF RL   Nat Commun. 2019;10:516.
#=GF DR   INTERPRO; IPR045923;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001877) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, polyketide, in particular
#=GF CC   the  cyphomycin biosynthetic gene cluster from Streptomyces sp.
#=GF CC   ISID311 [1]. 
#=GF SQ   21
#=GS A0A7W7XFR1_9ACTN/1-99  AC A0A7W7XFR1.1
#=GS A0A6G4VIK5_9ACTN/1-99  AC A0A6G4VIK5.1
#=GS A0A6I5C390_9ACTN/1-99  AC A0A6I5C390.1
#=GS A0A7Z0PS11_9ACTN/1-99  AC A0A7Z0PS11.1
#=GS A0A1S2K2R1_9ACTN/1-99  AC A0A1S2K2R1.1
#=GS Q2SJ05_HAHCH/5-103     AC Q2SJ05.1
#=GS A0A6I2FRR0_9NOCA/1-99  AC A0A6I2FRR0.1
#=GS A0A849BT77_9NOCA/1-98  AC A0A849BT77.1
#=GS A0A7Y5XMK0_9ACTN/1-64  AC A0A7Y5XMK0.1
#=GS A0A2P8AW42_9ACTN/1-99  AC A0A2P8AW42.1
#=GS A0A3N1AQA8_9ACTN/1-86  AC A0A3N1AQA8.1
#=GS Q2J4E1_FRACC/1-99      AC Q2J4E1.1
#=GS A0A160NZH9_STRLU/1-63  AC A0A160NZH9.1
#=GS A0A1C5BDI6_9ACTN/1-99  AC A0A1C5BDI6.1
#=GS A0A2P2GLU1_9ACTN/1-99  AC A0A2P2GLU1.1
#=GS A0A117RWQ1_9ACTN/1-99  AC A0A117RWQ1.1
#=GS A0A1S1R554_9ACTN/1-99  AC A0A1S1R554.1
#=GS A0A7Y0FZV5_9ACTN/1-99  AC A0A7Y0FZV5.1
#=GS A0A7K2YF64_9ACTN/1-99  AC A0A7K2YF64.1
#=GS A0A6M1L6Y8_9ACTN/1-79  AC A0A6M1L6Y8.1
#=GS A0A1M5ZUX8_9ACTN/1-99  AC A0A1M5ZUX8.1
A0A7W7XFR1_9ACTN/1-99             .MADIDLGVASDWDEGDTHGRVKLRQNQVYPSSP.KKDVLISSPVSIELSVNTNYSSSQEADKIYFTTHHGSTKKIIGVLDSDGNLYIAGRVITDQKDLRY....
A0A6G4VIK5_9ACTN/1-99             .MPDIDLGLATDWEEGDTHGRVKLRPNQVYPNSP.KKDVLISSPVSIELSVNTNLSTSQEADKVYFTTHHGRTKKVIAILDSNGDLYIAGRLITEQKDLRY....
A0A6I5C390_9ACTN/1-99             .MADIDLGVASDWDEGDTHGRVKLRQNQVYPTSP.KKDVLISSPVSIELSVNTNYSSSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITDQKNLGY....
A0A7Z0PS11_9ACTN/1-99             .MADIDLGVASDWDEGDTHGRVKLRQNQVYPNSP.KKDVLISSPVSIELSVNTNHSSSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITEQKDLGY....
A0A1S2K2R1_9ACTN/1-99             .MPDIDLGVATDWDEGDTHGRVRLRQNQVYPNSP.KKDVLISSPVSIELSVNSNYSTSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITEQKDLHY....
Q2SJ05_HAHCH/5-103                .MPDLDLGLATDWDEGDTHGRVRLRQNQKYPSSP.KKDVLISSPVSIELCVNTNYSTSQEADKIFFTTHYGCMKKVIGVLDSQGNLSISGRLMEMQNNLSY....
A0A6I2FRR0_9NOCA/1-99             .MPDVDLGLASDWNEGDTHGRVRLRDNQVYPNTP.KKDVLISSPVSIEFSVNTNYSTSQEADKIFFTTYIGNVKKIIAILDSRGDLRIAGKIIQDQTDMKY....
A0A849BT77_9NOCA/1-98             .MPDIDLGLATDWNEGDTHGRVKLRQNQVYPTSP.KKDVLISSPVSIELCVNTNYSTSQEADKIFFTTHHGSQKKIIAVLDSEGNLAIAGRVMEQQS----lky.
A0A7Y5XMK0_9ACTN/1-64             .MADIDLGVATDWDEGDTHARISLRQNQTYPSAPgKKDLVISAPLSIELAVNSNGSTSQEADKIY------------------------------------....
A0A2P8AW42_9ACTN/1-99             .MPDVDLGLASDWDEGDTHGRIKLRQNQCYPDSP.KKDVLISSPVSIELSVNTNYSTSQEADKIFFTTHHGNQKKIIAILDSDGNLKIAGRVTEMQTNLQY....
A0A3N1AQA8_9ACTN/1-86             .MPDVDLGLATDWDEGDTPGRIRLRQNQVYDHSP.KKDVVISSPVSIELSVNTNYSTSQEADKIFFTTHYGSEKKIIAVLDSRG-----------------gpvh
Q2J4E1_FRACC/1-99                 .MAEIDLGLATDWDEGDTHGRIRLRQNQKYPNSP.KKDVLISSPVSIELSVNTNYSTSQEADKIFFTTHHGNQKKIIAILDSNGDLYIAGRVIEGQSNLSY....
A0A160NZH9_STRLU/1-63             m---------------------------------.----VISSPVSIELSVNTNFSSSQEADKIYFTTHHGSTKKIIGILDSNGDLYIAGRVITDQKDLR-f...
A0A1C5BDI6_9ACTN/1-99             .MAELDLGPATDWNEGEPNGRVKLVQNQTYPGSA.QKNVAVISPNSVEIVINSNTSSSQEMDKVYFVTHHGSTRKVVGILDSDGNLQIAGKLITDQKNLNL....
A0A2P2GLU1_9ACTN/1-99             .MADIDLGVASDWDEGDTHGRIRLRDNQVYPGSP.KKDVLISSPVSIELSVNTNHSSSQEADKIYFTTYHGSTKKIIAVLDSDGNLRIAGRLITEQKDLGY....
A0A117RWQ1_9ACTN/1-99             .MADIDLGVATDWDEGDTHGRVKLRQNQVYPNSP.KKDVLISSPVSIELSVNTNNSTSQEADKIYFTTYHGSTKKIIAVLDSDGNLQIAGRLITEQKDLRY....
A0A1S1R554_9ACTN/1-99             .MADVDLGLASDWEEGDTHGRVKLRQNQKYPTSP.KKDVLISSPVSIELSVNTNYSTSQEADKIFFTTHHGNQKKIIAVLDSNGDLYIAGRVIEGQSNLSY....
A0A7Y0FZV5_9ACTN/1-99             .MADIDLGVASDWDEGDTHGRVTLRQNQVYPTSP.KKDVLISSPVSIELSVNTNHSSSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITEQKDLGY....
A0A7K2YF64_9ACTN/1-99             .MPDIDLGLATDWDEGDTHGRVKLVQNRTYPTSP.KKDVAITSPNCIEIQVNSEFSTSQEADKVFFTTHYGSTKKVIAVLDSQGNLSIAGKLTTDQKNLGF....
A0A6M1L6Y8_9ACTN/1-79             .--------------------MRLRQNQFYPDEP.KKDVIISSPLSIELSVNTNYSTSREADKISFTTHHGSTKRIIAILDSEGNLQIAGRVMEMQRDLRY....
A0A1M5ZUX8_9ACTN/1-99             .MADIDLGLATDWNEGDTHGRIRLRQNQVYPNSP.KKDVLISSPVSIELSVNTNNSTSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITEQKDLAY....
#=GC seq_cons                     .MsDIDLGlAoDWDEGDTHGRV+LRQNQsYPsSP.KKDVLISSPVSIELSVNTNaSTSQEADKIaFTTHHGSTKKIIAVLDScGNLpIAGRlIp-Q+sLtY....
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