#=GF ID DUF6418
#=GF AC PF19982.3
#=GF DE Family of unknown function (DUF6418)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 25.00 25.00;
#=GF TC 31.20 31.20;
#=GF NC 23.70 23.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 28658258
#=GF RT Genome-scale analysis of the genes that contribute to
#=GF RT Burkholderia pseudomallei biofilm formation identifies a crucial
#=GF RT exopolysaccharide biosynthesis gene cluster.
#=GF RA Borlee GI, Plumley BA, Martin KH, Somprasong N, Mangalea MR,
#=GF RA Islam MN, Burtnick MN, Brett PJ, Steinmetz I, AuCoin DP, Belisle
#=GF RA JT, Crick DC, Schweizer HP, Borlee BR;
#=GF RL PLoS Negl Trop Dis. 2017;11:e0005689.
#=GF DR INTERPRO; IPR046303;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0001589) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, saccharide, in particular
#=GF CC the exopolysaccharides biosynthetic gene cluster from
#=GF CC Burkholderia cenocepacia J2315 [1]. This family appears to be
#=GF CC predominantly found in Proteobacteria.
#=GF SQ 30
#=GS A0A147EFM0_9SPHN/304-417 AC A0A147EFM0.1
#=GS A0A448NYH3_9ACTN/364-468 AC A0A448NYH3.1
#=GS A0A099XZS3_9FLAO/292-401 AC A0A099XZS3.1
#=GS A0A844YJI4_9SPHN/319-430 AC A0A844YJI4.1
#=GS A0A5B0H6B2_9BURK/345-453 AC A0A5B0H6B2.1
#=GS L0M4C5_ENTBF/310-418 AC L0M4C5.1
#=GS A0A5J4IMW1_9FLAO/62-177 AC A0A5J4IMW1.1
#=GS A0A848FED4_9BURK/352-461 AC A0A848FED4.1
#=GS A0A4Q2ZHP9_9SPHI/345-453 AC A0A4Q2ZHP9.1
#=GS A0A520FVE9_SPHSX/267-375 AC A0A520FVE9.1
#=GS A0A0S9CBC6_9SPHN/360-468 AC A0A0S9CBC6.1
#=GS A0A160FHK0_9BURK/345-453 AC A0A160FHK0.1
#=GS A0A087BZP1_9BIFI/139-246 AC A0A087BZP1.1
#=GS A6VMJ1_ACTSZ/313-421 AC A6VMJ1.1
#=GS A0A137RKC4_9FLAO/296-407 AC A0A137RKC4.1
#=GS I9L9J2_9SPHN/327-437 AC I9L9J2.1
#=GS A0A1H1RUW4_9FLAO/292-402 AC A0A1H1RUW4.1
#=GS A0A2S2FHD5_9GAMM/319-427 AC A0A2S2FHD5.1
#=GS A0A1G8YTI9_9PSED/294-400 AC A0A1G8YTI9.1
#=GS A0A5C4SST0_9FLAO/285-394 AC A0A5C4SST0.1
#=GS A0A433HE24_9BACI/310-418 AC A0A433HE24.1
#=GS A0A158GK11_9BURK/350-458 AC A0A158GK11.1
#=GS A0A0B3BP77_9PSED/306-414 AC A0A0B3BP77.1
#=GS A0A0H3KQV7_BURM1/341-449 AC A0A0H3KQV7.1
#=GS A4JN75_BURVG/348-456 AC A4JN75.1
#=GS A3WG49_9SPHN/322-428 AC A3WG49.1
#=GS A0A3L9YZ35_9FLAO/295-406 AC A0A3L9YZ35.1
#=GS Q1GSU1_SPHAL/318-425 AC Q1GSU1.1
#=GS A0A7K3L2T2_9ACTN/142-248 AC A0A7K3L2T2.1
#=GS A0A5C7B9R1_9FLAO/280-391 AC A0A5C7B9R1.1
A0A147EFM0_9SPHN/304-417 ....alr---NGIGPAYFMNRYAPSK..FRAAQMRGGglITYTMALEPLALVMFGWFGLVL.TLIVSGFLFAAGACYLAYAIERRLMP.SMIFAGYLIVMLKSYSA.QGAPWvvvSIFTLKWLSVV............
A0A448NYH3_9ACTN/364-468 ......a-PSTQSGIYVLMDALSPS-..---GANQAG..YTLNSGYPAILIYIFGSGLATVgVCFLGGLLFGLIALVVAHSILRGSML.LAACGYGVLYSLYLAFT.MGGAL...YIS--------srlmyvs.....
A0A099XZS3_9FLAO/292-401 .....vl--ELWKGMHHLMLEFWPWRyqDFISVTTRG..VSWTNAYPSILIRIFPLPLALV.ANFFLISFVSLIQTLLSIFIKRKSLF.ISIILFQLLIWTSYAYT.MAYFS...KLL-IPFFFI-l...........
A0A844YJI4_9SPHN/319-430 ...dsnv----NTSIKYLMINEVGFF..RTEELLANG..TQFAGGYPEIYLSLFGMFWAIP.LMVLIGICTAWITRLAMRNIFRGYLL.SSIMAIYVMFAFHLGYI.GGMLN...SLLAYTFY---lkilil......
A0A5B0H6B2_9BURK/345-453 ....dsf---GYSGLRDVMVAYGDPR..LISVYIKDD..VTFTMGQMAIPVFWFGLAGGAL.FVAFTGVIFGALCALQIVFALRGGVV.MLWLVVKVLSYAGSGIQ.QGDYW...SFFSVRTLFYV............
L0M4C5_ENTBF/310-418 ......t-EERDKGIFYLMSQITPLN..IFEGYYEKK..INFTMASPVNIIYFFGYGFSLF.IAIPIGFLCGIMLGIFRIAVINSDYW.IVLLFVKIQYTIVRIFT.MGEMY...AFSEPKFLILC............
A0A5J4IMW1_9FLAO/62-177 .....pa--DLLYGMPIMMEEFAADKkmVLTANNTGG..YNFTNAYPGILFKIFPVSLALVyHTILVIGFLALMGWVLKELMVKKAYF.LSIIAYQLFNWTIYAFV.MGYFY...KLY--------fafgflavyflf
A0A848FED4_9BURK/352-461 .tfqhrl------APFYFVERYAPTV..LFLSFVNNGgmVTPTMVFEAYSLVMVGYAGLAL.ALLLAGVWTGWLAHHLARAMAGGNPA.DVLLPSFAMFQTIVLMS.QGTLH...SLLSLSA----fka.........
A0A4Q2ZHP9_9SPHI/345-453 ..rsapy-----IGARDFMSQYLETP..RYNSYVERG..VTLTMATEGYLLKVFGWFAGIP.FYWVLLAVYALQVLYFAYALNTYNPL.RIIIACKLLVWSNYGLN.QGYLW...EVIGLPVLA--lm..........
A0A520FVE9_SPHSX/267-375 asakgie-------TFYFIHHYAPAW..LANAIRKNQgwVQFTMGTEAMALVMFGYIGVAT.VMVLAGGLVALLSLYLRRTFASGFPV.SLYFAVWAYLQVYLTVQ.QARFW...SIA--------apgqlk......
A0A0S9CBC6_9SPHN/360-468 ......t-AGTRFGLYYVMQPFTASR..LLGWAMEGG..TGFVFSLYPYLLMTMGIVGLLI.VSSIIAAFHAFVMNMLAQTIAQGNWI.ASILLGRMMSSLYGGYT.TGFLW...NFFGIKNLVT-l...........
A0A160FHK0_9BURK/345-453 ....dsf---GYSGLRDVMVAYGEPH..VITGYIKDD..ITFTMGQMAIPVFWFGLAGGAL.FVALTGVIYGALCALQIVFALRGGVI.MLWLVVKVLSYASSGLQ.QGDYW...SFFGVRTLFYV............
A0A087BZP1_9BIFI/139-246 .....np----DSGVYGLMQKYSQSD..IVENYISHK..VRFSANFFAVSLFYNGIIITVI.AIAINAIILVTFLKLFSDDAIHQRSL.AFVILFRIFQIFSTYVTgSGTLT...EFYRINVLLLI............
A6VMJ1_ACTSZ/313-421 ......l-NQYDVGMYKVMQLNTTPE..RFEWKLDKL..SRYVYSTPALLYYYLGKYTGAF.AMLFLGFLLGGWVKLVGYTISSGDLF.MSLIAARFFYIIRKGVK.DGDIY...KFFSLEFIFLI............
A0A137RKC4_9FLAO/296-407 .....pa--DLLYGMRVMMDDFAKDRkmVISANEEGG..YNFTNAYPGILFKIFPLSIGLVfHTFLTIVFLALLGWMLKELMVKGAMV.LSIIAYQLFNWTIYAFV.MGYFY...KLY-FTIFF--lfl.........
I9L9J2_9SPHN/327-437 ......a-FDTRTGIFHMVVLFAPDN..IRNSIFNASgyVQFTGASEAYLALLLGQIPMAF.LIMALAVTCGLLVYYVYNALWAGSMP.SYFIALFILSNFASMLN.QASFW...QIFGARALMYI............
A0A1H1RUW4_9FLAO/292-402 .....vl--ELWKGMHHLMLEFWPWRyqDFISVTTRG..VSWTNAYPSILIRIFPLPLALF.ANFILMSFVALMQTLLTVFIKRKSLF.VSLILFQLLIWTSYAYT.MAYFS...KLT-IPVFFI-la..........
A0A2S2FHD5_9GAMM/319-427 ......e-SDRESGTYYLMDQVSSKS..LVDARFETQ..SKFTMSGFFNHVYYFGYWLGAL.LNFLWGAFFGFLCYLLYLGIKCKNII.YSFISFKFLYKVQALFL.VGSIT...DFFTIGTLVF-s...........
A0A1G8YTI9_9PSED/294-400 .....pa--GLWDGMENVMLLISPD-..IADGMIERG..VRFTFGYFASLVVHLGVF-AFP.AALIFGVLHSAIAIRVVKAVLERDLI.GYFLLANMLVMYNGFIS.MGSLS...GLLNLKLLFLL............
A0A5C4SST0_9FLAO/285-394 ......s--ELWKGMHLIMLEFWPWRneDFISVTSRG..VSWTNAYPSILLRIFPLPLALI.VNMFLLSFVAIIQELLRKFIESKSII.SSIVFFQLLVWTSYAYT.MAYFN...KLVIPVVLLF-i...........
A0A433HE24_9BACI/310-418 .....dg--KYTSGLNALMLLVSPS-..MGLGFIENG..VSFTMGFPAILNIMFNPIALFF.VLIICGIFFGLFIYVFYRSIQSFNLIyMGFLGYIYIYGIIQLFT.MGRMS...YLFNLKMYLII............
A0A158GK11_9BURK/350-458 .....nd--GAVSGLRDVMLAYGTPD..VLRAYVRDD..VTFTMGQMAVPVYWFGFAGAAL.FIALTGVVYGALAAAQIVVTQRGGVV.MLWLVTKIVSYVGFGLQ.QGEYW...NLFGLRTLGYV............
A0A0B3BP77_9PSED/306-414 ......d-DSDSVGMRYMMKKLAPEY..LYSSYLESG..VEYTGGYPAILVLIFGLFGGVL.FSVVLWGFYGFFLFYLARLIFIGSRV.RLFFSSYLYITSFAWFQ.HGSIS...SFINWKFLVVC............
A0A0H3KQV7_BURM1/341-449 .....sd--AEPSGLRDLMMSYTEPK..LLKAYIFDD..VTFTMGNMAIPVYWFGYVGGAL.FVAMTGLVYGALGALQIQVAMRGGVV.MLWLMSKVFSYATFAVQ.QGEYW...MMFGSRTLFY-a...........
A4JN75_BURVG/348-456 ......d-ESEPSGLRDLMMSYTEPS..VLRAYMFDD..VTFTMGNMAVPVYWFGYAGGAL.FVAMTGLVYGALGALQILVAMRGGVV.MLWLIAKVFSYATFAVQ.QGEYW...MMFGSRTAFY-a...........
A3WG49_9SPHN/322-428 .......DPSRNSTIQYLMTLELGYF..RTAELTQLG..QAYNGGYPEVHFELLGAWLPFV.TLPLAGIITAWFLSLFLKLLYRNLIL.TSVLGLYVYFGITLHYT.GGMLT...FL---------laptywv.....
A0A3L9YZ35_9FLAO/295-406 .....pt--DLLYGMPVMMKEYAKDKkmVLNANAEGG..YNFTNAYPGILFQIFPLSMALVfHTFLTICFLALMGWMLKEFMTQGAWF.LSVIAYQLFNWVLYAFV.MGYFY...KLY-FTIFFFVv...........
Q1GSU1_SPHAL/318-425 ......r-PEGNTTIYYLMERELGFF..RAEELIEAG..QQYAGGYPEIFFLLFGVLPAIP.LMILFGTATVFVLYCAVRSFARGRPL.TCIMALYVFYGFSLCYI.GG-ML...NFIIAPTF---lvk.........
A0A7K3L2T2_9ACTN/142-248 ....nkg---STHGIYGMMYLNAPTD..LVDGKLAQG..SRYTEGGYAAMYYSGGLTGVLL.FSLAMSGIFFFVIRGLGVALKRGRAI.EVVMLARLFIVLQTALS.MGTFA...DLID-------pvslg.......
A0A5C7B9R1_9FLAO/280-391 .....pl--DLSYGMQHLMREFAAKK.sNLDKAISNG..FNFTNGYPSILFYTYPIFLALIlHILVTAILIAFPGWLLIQFIKARAYV.MAVILFQFFNWAIYAIT.MGYFY...KFN--------fiigfllly...
#=GC seq_cons ......t..th.pGhhhlMhpaussp..lhpuhhpsG..lsFThuh.ulhlhhFGhhhuhl.hhhlhushhuhlshhlhpslhpushl.hsllshplhhhhthuhs.hGthh...plhthphhhh.............
//
