#=GF ID   DUF6657
#=GF AC   PF20362.2
#=GF DE   Family of unknown function (DUF6657)
#=GF AU   Paysan-Lafosse T;0000-0001-5663-0894
#=GF SE   MGnify-UniProt clustering
#=GF GA   27.00 27.00;
#=GF TC   27.60 27.10;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR046598;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria. Proteins in this family
#=GF CC   are approximately 200 amino acids in length.
#=GF SQ   37
#=GS A0A7T7XRE1_9SPIR/50-190  AC A0A7T7XRE1.1
#=GS F8F376_GRAC1/51-191      AC F8F376.1
#=GS F5YAI2_LEAAZ/50-190      AC F5YAI2.1
#=GS D6Z4X2_DESAT/55-196      AC D6Z4X2.1
#=GS A0A2L1GPI5_9DELT/54-195  AC A0A2L1GPI5.1
#=GS A0A5C1QMF5_9SPIO/51-192  AC A0A5C1QMF5.1
#=GS A0A3N5AY67_9THEO/50-191  AC A0A3N5AY67.1
#=GS A0A5C1Q7R0_9SPIO/50-190  AC A0A5C1Q7R0.1
#=GS V5WEZ8_9SPIO/50-191      AC V5WEZ8.1
#=GS A0A4R4BRV4_9SPIR/51-191  AC A0A4R4BRV4.1
#=GS A0A1W9N9J0_9SPIO/51-195  AC A0A1W9N9J0.1
#=GS A5D2G9_PELTS/51-191      AC A5D2G9.1
#=GS A0A4Y7RDQ0_9FIRM/49-192  AC A0A4Y7RDQ0.1
#=GS A0A421K8K4_9SPIR/51-195  AC A0A421K8K4.1
#=GS H9UFW6_SPIAZ/75-216      AC H9UFW6.1
#=GS G8QUE2_SPHPG/51-194      AC G8QUE2.1
#=GS A0A098QUK1_9SPIO/50-191  AC A0A098QUK1.1
#=GS A0A179D4T6_9BACT/54-193  AC A0A179D4T6.1
#=GS E1RCC9_SEDSS/49-194      AC E1RCC9.1
#=GS F0RY41_SPHGB/56-194      AC F0RY41.1
#=GS A0A370APE7_9SPIO/63-204  AC A0A370APE7.1
#=GS A0A1M5VHR1_9DELT/52-192  AC A0A1M5VHR1.1
#=GS F4GM35_SPHCD/50-194      AC F4GM35.1
#=GS A0A5N8YHI4_9CHLR/50-194  AC A0A5N8YHI4.1
#=GS A0A1Y1S223_9SPIO/50-191  AC A0A1Y1S223.1
#=GS A0A4Y7RUT0_9FIRM/54-195  AC A0A4Y7RUT0.1
#=GS A0A0A2HXJ9_9DELT/52-190  AC A0A0A2HXJ9.1
#=GS A0A075WRF9_9BACT/56-195  AC A0A075WRF9.1
#=GS F5YIP7_TREPZ/50-190      AC F5YIP7.1
#=GS A0A6G7PTI0_9BACT/51-189  AC A0A6G7PTI0.1
#=GS A0A1N6VQ22_9SPIO/50-190  AC A0A1N6VQ22.1
#=GS Q6AS21_DESPS/50-188      AC Q6AS21.1
#=GS A0A1B9F3R3_9DELT/51-190  AC A0A1B9F3R3.1
#=GS G0GCS5_SPITZ/48-191      AC G0GCS5.1
#=GS M1P3M5_DESSD/51-193      AC M1P3M5.1
#=GS A0A841RDH9_9SPIO/50-191  AC A0A841RDH9.1
#=GS A0A7U3YJY3_DESPD/51-191  AC A0A7U3YJY3.1
A0A7T7XRE1_9SPIR/50-190             ...............EAEIKKAPADQRDSLKEGLFDVLVSQIALP...AG...KDDEKR-IAAVGKGL.SVL..I....P....D.S.R.F.SAL..YGQLTQALTQYLD.E....TE....QFEQM....LKQQYGPKLRQKEEELSRRMGQQ...V..R...LDPFQDPEFVAFYNQNMGALKDRYQSAVDQVREEAQ-k.....
F8F376_GRAC1/51-191                 ...............EDSLKKYPKDKQEALRQGMFDVLVSQIRLP...AH...QEDITKQ-EAVGKAI.QLL..V....N....D.R.R.F.GQL..YSQLVQAFERYLS.E....VD....QFDQA....IRRQYAPKLRQKEEELARRLGRA...V..Q...LDPFQDPEFVNFYNQNMNALKARYEQAIEQVRQQA--tm....
F5YAI2_LEAAZ/50-190                 ...............EDEFKKAPKDEQASLKQGAFEVLLAQLTLP...AS...EEDLPR-IETVGKGL.EAV..L....K....D.N.K.F.SAF..FKQLSQALKQFLD.E....TA....QYEEA....IKRQYAPKLKQKEEELSRRMGRQ...I..Q...LDPFQDPEFVAFYNQNMNQLKANYQAAVDQVREEASR......
D6Z4X2_DESAT/55-196                 ............aad---LTAAPPEKQAALRRGMFQTLARNIFLP...RD...EEQLGPAERAMAGMV.ALA..G....G....S.G.E.L.LRF..LGELKKVLEQYLN.H....QK....QLRQQ....LAEQFAQEMARLEGQLAAQTGMS...P..N...LRPEQHPKFQEEWQRVLDELNSQYGRALEQYKEQ---irq...
A0A2L1GPI5_9DELT/54-195             .............ag--HLTKAPEAERGTLRRGMLATMLHNLFLP...RD...ESGKKR-VERALAGL.LAL..H....G...gA.R.Q.A.AAL..CAQLAQLASRYEE.H....RK....QIQEQ....LKEQLRMQLQQSLAQERGIKVDA...S..K...IDPALDPRFAQEWGRIEAELNSQYGQALEQCRS----qlfa..
A0A5C1QMF5_9SPIO/51-192             .............ke--KLKSLKGEELEWFKTGAAEAFLANLTLP...RI...EADVSK-LPALSDAL.GVL..T...gK....K.K.E.I.EEM..FGQLEQLFTQYLS.N....LD....HLEES....LKKQYEPQLRQKELKMRQQTGQS...V..Q...LTPEQDPEFLQLLSDQMSRMDQQYNEVLKQAKDQ---lkq...
A0A3N5AY67_9THEO/50-191             .............lg--ELNRYPEDVRGYVRKGMEETLLQNIQLP...AD...ENTYETNRRAMEGLL.ALK..K....N....K.S.A.L.KQV..FSELEYLFNYYTR.A....FE....HTYAN....LKESFAARLEQAQEALQRQLGVK...V..R...VDVERHPAFLEEWLRVQGELNGQYETILAEQK-----ekirs.
A0A5C1Q7R0_9SPIO/50-190             .........kwftel-------ENDNKNEILQGVVWVFVKNITLP...NS...TADIDK-LLKIKEGF.LLI..S....N...kK.E.E.I.ENI..FTQLITAFQQYID.N....SK....TLLEQ....AKTEFAPRLQQKAMQIAQQTGQM...I..P...IEPETDRDFIEFHRDQQIQVDDHYKEYIKQATE----vlke..
V5WEZ8_9SPIO/50-191                 ...............EKELKQFGKDERKEVLSGLMDSVLARITLP...ST...DQSLDD-ISIIAGAL.KFL..F....P....G.N.KaM.EGV..PEQLREFYQNYLQ.D....KE....RLLDA....LKERFADHLKQKEEQMARQTGQR...M..S...IRPEMDPEFNKALQANLEHLDGQYQQVIDNVRREL--kq....
A0A4R4BRV4_9SPIR/51-191             ...............EEAIKKCPKEELPALKRGIFEMLLSQIQLP...EN...QDHLSK-IERIFRGM.QLI..L....T....D.R.R.L.PQL..FNQVMQAFSRFLQ.E....QQ....QYEET....IKRQYAPKLRQKEEELARRLGQR...I..R...LDPFQDPEFVAFYNQNMNMLKGQYQALVDEVRQH---leq...
A0A1W9N9J0_9SPIO/51-195             ..............q-EELKKADKPEAGWIKEGILETLLANLTLP...RY...ESDIDK-LTPVAAGL.KVL..A....GkgpgS.R.N.L.DYI..LDQYKKLFQQYME.N....LG....QLETG....LRAQWAPRLRQKEEMLRKQTGQS...F..A...LAPEQDPEYNKVLSEQIAEMDAQYNEVIDRSKAE---irk...
A5D2G9_PELTS/51-191                 .............la--EIGKYPENVRQYVIEGAQETFLNNIYLP...VD...RLSLESS-QKAMKGL.SLL..K....K....D.R.QsL.EKA..YSQLKYLFQYYEQ.A....LA....QTYSQ....FKEGFAAKINATVKSLERRTGTK...L..K...ADPEKQPGFREEWSKVLSMLNSQYEVPLKEQ------kerlr.
A0A4Y7RDQ0_9FIRM/49-192             ...........dmmv--EVAKYPQQFQGYVLEGIQKTLLSNLLPP...ID...KNTLEDNLRAM-QGL.LLV..K....K....D.K.DaV.KEV..LGQLENLFQYYEQ.A....LT....QTYSQ....FKQQFTEKLSPSIRAMEKRTGQK...F..K...IDPEKQPGFRDEWNKVVSRLNLQYEQVLDEQKE----klrn..
A0A421K8K4_9SPIR/51-195             ............ekq---WQEIEKKEAAWLREGMLDILLSNFTLP...RY...ETDMLR-LRTISKGL.QAL..AgkgsA....K.K.N.I.GDV..MDQCQNLFKQYME.N....VE....QLEES....LRLQWEPRMRQKEELLRQQTGQS...F..K...LSPDQDPEFAKSLSEHLAELDAQYNEVIRKGRMEI--rr....
H9UFW6_SPIAZ/75-216                 .............qq--RLKQYPEDEQQLVREGLTEVLLAGITLP...QD...ETYRDT-LERVRQAA.YAI..S...sN....A.A.M.I.EQL..FQQAFQILDQYLQ.E....RQ....QLLDN....LRQQFEPRMRQKAEAYAQQTGQR...V..S...LDPATDPEFQKYLQQANDQLQDYYGQAVQQIRDQ---lrq...
G8QUE2_SPHPG/51-194                 ...........etle--KFSAYPAEEQKAVTEGMALTLLANLTLP...RTekfQESFAK-ITELGNII.AP-..-....E....N.E.D.L.TSL..MGQLEAFFSQYFK.N....QE....DMIER....MKQQFAPQLEQKQAQLRQQYGPN...F..M...LRPEQDPEFMKLLDKNLSQLDTQYNNILMQAKNQ---ikg...
A0A098QUK1_9SPIO/50-191             .............aq--EITKAPKEDQEQLRRGLFQTALTRLQLP...QT...EAALHD-LPAVTRAL.IAT..G...aE....A.S.A.A.TQI..MDQLQSLFDRYLQ.D....RD....QLYNA....VVQQYTPVLRQKEQQLAQQTGRK...V..T...LTPEQDPEFQKYFKQNLDQLEEQYQQMVDQARSQL--qt....
A0A179D4T6_9BACT/54-193             eiarlnpsekgpfik-----------------GIIFTLLRNINLP...RD...EYALEGA-KKALLGL.EIV..F....-....-.-.-.-.SAFpdVKQLTQEIERLLS.Q....YL....QHRKAlyeqLKQQFESQLAGVEEALRNQMGVQ...V..Q...VDVEMQPQFQEEWRKVRDQLDPQYERQLEYLK-----nifak.
E1RCC9_SEDSS/49-194                 .........sdelak--ALKETKKEDRGPVKTSTIEVLLSNITLP...RE...EVDEEL-LKRIEEGI.AVV..T....G....E.K.K.QaTNT..LDQLTQFFQQYLQ.N....RE....QILDH....LKRQYQPQLDAKQEALSRQYGQK...V..A...LQPEQDPDFMQLLNRNIGRLEEQYQQALDQAKGE---ire...
F0RY41_SPHGB/56-194                 ............yda------VPAEEKEAFKEGMTLTMLSNLALPrnaAF...KDAFTK---VLDLGL.ILG..E....G....N.D.Q.V.VQL..LGQLEGFFTQYLE.N....QE....DLVER....MKQQFAPALQQKEAQLRKQYGPN...F..T...LRPEQDPEFMKLLDKQLSQLDEQYTNILTQAKA----qike..
A0A370APE7_9SPIO/63-204             ..............i-DKMKFYKDEELGWFKNGAMDTILANITLP...RL...ESDSNK-LIPLNAAL.AIV..S....G....D.K.EeT.DSM..FEQLKQLFSQYLS.N....LD....QLEAS....MKQQYEPQLRQKEQQLSQQSGQE...V..H...LTPEQDPEFLKVLSEQISRMDQQYQDVLKQAKDQ---irk...
A0A1M5VHR1_9DELT/52-192             .............qv---LEQQPVEKQSAIRNGMAIALLRNIILP...RG...QG-LSDQTLQSFKGL.QEL..S...gN....A.P.D.I.MSI..CSELKQILEQYGQ.H....QEqvrqQFDES....IMNQLKMQLQQQGM----QIDDT...M..A...LSPTMHPHYKEEWARVSADLNSQYNQALEQRKQ----liaq..
F4GM35_SPHCD/50-194                 ........edflsay----EAYPSSAKAAVREGVLTTLLSNISLP..qAD...QHDASA--DRLRTLI.VAL..A....G....E.KpE.A.MGL..FDQIIGFYNQYIT.V....QK....ELLDR....LKQQYQPTLEQRQAAMRKQYGSN...F..T...LKAEQDPDFIKLLERNYKQLDAQYGQALDQAKT----qlke..
A0A5N8YHI4_9CHLR/50-194             ..............f-DDLESFEKDDQPYLVKGMIEVFVSNVQIP...KS...EAQKETN-ARVIDGI.RRV..L....G....D.RpK.C.GEA..LEHLEYVLEQYWQfG....RE....QRTQA....FEQLKAQIEQQVYEVLSRQTGGS...H..QgmkVNVEAMPEFQQQWLRISGQLNVPYETHLQE-------ykkqim
A0A1Y1S223_9SPIO/50-191             ..........saalt-----EAKNEEAEWLREGSFSVLAANLTLP...QD...ESYKER-LERVREGL.VAV..T....G....QkK.Q.V.SYL..FEQVEQFFEQYLE.N....QE....QLIQA....LEKQFAPRLRQREQEMERQFGQR...V..S...LNPAQDPEFSKMLKQHLGKLEAQYSEALKQAKDQ---lra...
A0A4Y7RUT0_9FIRM/54-195             ............lse---VEKQAGDLRKYIIEGVQETFLNNLQMP...GD...KDTMEANKKAM-EGL.LLI.kK....N....K.N.A.L.KET..FGQLEHLFQYYER.T....ME....QAFGQ....FKERYAAKMSASLKKLEQRTGQK...I..K...ADPEKQPGFREEWMRAVSGINNQYEQLLREQKE----kira..
A0A0A2HXJ9_9DELT/52-190             .......stlaelap---------AEQAAVRQGMIETLLRNITLP...RD...EQLKTTS-LLALKGI.IA-..L....G....G.S.Q.I.APV..SAELQQLLEQYSQ.HkeqsIK....QLDDA....IRTQLGQQ-------MARRGGEA...T..QaaaLNPALHPQYREELARMQSDLNNQYTQAFDQRKE----lirq..
A0A075WRF9_9BACT/56-195             ...........etml----KDRKPQEKKAILKGMVQVFLRNIVLP...LN...EDQLEDG-KKALKGL.KLL..F....D....K.MpD.M.DRL..LKEIEKLLIQYNT.H....KE....TIYQQ....MVERFSAEIEMIEQALSSQLGAE...V..H...VDPENHPKFKEEWRKIKEKLDEEYNRQLEY-------lkgif.
F5YIP7_TREPZ/50-190                 ...............EGELKKTPKDQLAALKQGIFDALITQVALP...AV...ADDEKR-IEAAGKGL.QAV..I....G....D.P.R.F.GAL..YKQFIQGISRYLS.E....TA....QYDAA....IKQQYAPKLRQKEEELTRRLGRP...V..Q...LDPFQDPEFVGFYNQNMNALKDNYQAMVNQVREQA--vq....
A0A6G7PTI0_9BACT/51-189             ...............EEEIKKVPPQEIHVLLEGLEEVFLRNIFLP...RD...QDSLTHTISRALEGL.R-L..I....K....G.P.Q.A.SRI..LQEIERLLLGYLQ.M....KS....DLYQR....FRQQFQSNMAGLEQAIAQQYGLS...G..P...IDPEALPQFQEEWQKVEADLKERFQQQLNQLK-----aal...
A0A1N6VQ22_9SPIO/50-190             .............kk--ALKAFPKNELVWVKEGLFEAVRSNLVLP...QE...ERDLAR-LDELATVM.KEL..S....R....D.R.S.MvDAI..LQQVREFFSRYLQ.D....RN....QLIEG....LTEQYGPRLKQREQQLSQQYGRP...V..R...LEASQDPEFAKLLQDHLGNLQEQYQRALGEVE-----thlr..
Q6AS21_DESPS/50-188                 .............ma--SLRAQDEDKQTSMKSGILQTLLRNITLP...RD...T-DMQA---AAHKAL.SGL..I....E....L.C.Q.G.VEE..PANICTELQTIVD.Q....YA....QHKEQ....STEQLENALRDQMQQQYAAQGRE...G..Q..eVNPVAHPQYAAELSKMLDDLNQQYTQAIEQRKE----iitq..
A0A1B9F3R3_9DELT/51-190             .............kd--GFGEIPPENINKAIEGATDVLIRNIILP...RD...KYQWAN----INKAI.EGIieL....K....G.S.T.I.RQV..TDRIIELLKMYEH.S....IN....QYQEQ....VKMQFQAKLGGYQQAIAQQYGAE...VaaN...IDVEAIPEFQQEWSKIKGEIDSQFEQQLEQMK-----sfl...
G0GCS5_SPITZ/48-191                 ..........dikke---LKGLSAEQRSWFVKGSVETFLANLTLP...SR...EEELER-LPLVMEGL.RKV..L....G....E.ApL.F.GML..EQQLSQFFSQYLA.T....YR....QVETA....LLQQFAPRFREKETLLSQQLGMP...V..K...VAPESDPEYQAAFRQHIGQVRAQYEQHLSQVKAQ---irk...
M1P3M5_DESSD/51-193                 .......sallqqeg--------TTDQAAVRRGMVKALVRNIVVP...RD...EMLMNSSATALSGLL.NLS..H...eA....D.D.E.V.QSV..CTELTQLLEQYAQ.H....KE....QIKHQ....LEDAIRAQLAQQLQEQTGESGDP...M..K...IDPTRHPQYQKEWSQAQANLNDQYTQAFEQRKE----ilkq..
A0A841RDH9_9SPIO/50-191             .............ke--KLSKFPEGDILFIKEGFAEILLSNIRLP...LY...INSDNR-LNQLEEAF.ALI..S....D....R.EdI.Y.KLV..FSQLQQLFGKYVE.D....IQ....NLSEA....LKQQYMPVLRQKQQQIRQQTGRD...I..P...IEPEQDPEFMELLSQNRRALEEQYNEVIAQAKAE---lkk...
A0A7U3YJY3_DESPD/51-191             .........tdvlaa------QEPDQRESIRKGMLTALLRNLFLP...RD...EDGIKR-IEQAVKGLiELN..Q....G....T.P.D.I.AAL..CRELQTIASQYGQ.H....RQ....QLYEQ....LKEQ----MRMQIEQLLMRKGLKadgM..K...IDPTMEPQFKEQWSRLEADLDGQYGQALEQFKA----qlka..
#=GC seq_cons                       .................tlpphsp-cpthl+cGhhcsLLsNlpLP...ps...csshpc.hptltcuL.thl..h....s....s.p.p.h.spl..hsQLpphhppYhp.p....hc....Qh.pp....l+pQatspLcQppptlppQhGpp...h..p...lcP-p-P-Ftc.hpcthupLcsQYppslcQh+t....hht...
//