#=GF ID DUF6871
#=GF AC PF21771.1
#=GF DE Domain of unknown function (DUF6871)
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE manual
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.00;
#=GF NC 26.60 26.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 32791035
#=GF RT Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar
#=GF RT Axoneme and Mitochondrial Sheath Defects and
#=GF RT Asthenoteratozoospermia in Humans and Mice.
#=GF RA He X, Liu C, Yang X, Lv M, Ni X, Li Q, Cheng H, Liu W, Tian S,
#=GF RA Wu H, Gao Y, Yang C, Tan Q, Cong J, Tang D, Zhang J, Song B,
#=GF RA Zhong Y, Li H, Zhi W, Mao X, Fu F, Ge L, Shen Q, Zhang M, Saiyin
#=GF RA H, Jin L, Xu Y, Zhou P, Wei Z, Zhang F, Cao Y;
#=GF RL Am J Hum Genet. 2020;107:514-526.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in Cilia- and flagella-associated protein
#=GF CC 58 (CFAP58), a human protein with an essential role in the
#=GF CC assembly and organisation of the sperm flagellar axoneme. This
#=GF CC domain is predicted to adopt an alpha-helical configuration [1].
#=GF CC Its specific function is unknown.
#=GF SQ 1540
#=GS A0CW96_PARTE/360-663 AC A0CW96.1
#=GS A0A6I8NZ88_ORNAN/478-711 AC A0A6I8NZ88.1
#=GS A0A7K7EII9_9SYLV/353-658 AC A0A7K7EII9.1
#=GS A0A093JLL3_FULGA/103-408 AC A0A093JLL3.1
#=GS A0A821MEN2_9BILA/1-64 AC A0A821MEN2.1
#=GS A0A8D0BR19_SALMN/362-667 AC A0A8D0BR19.1
#=GS A0A7J8D4E5_ROUAE/12-248 AC A0A7J8D4E5.1
#=GS A0A833TES0_PHYIN/377-682 AC A0A833TES0.1
#=GS A0A0G4EWH2_VITBC/406-669 AC A0A0G4EWH2.1
#=GS A0A8C0BI97_9AVES/366-671 AC A0A8C0BI97.1
#=GS A0A6A3ZQW6_9STRA/392-695 AC A0A6A3ZQW6.1
#=GS A0A8J5ARY8_9DIPT/271-574 AC A0A8J5ARY8.1
#=GS A0A816A5M0_ADIRI/394-683 AC A0A816A5M0.1
#=GS A0A0S4JNC8_BODSA/375-677 AC A0A0S4JNC8.1
#=GS A0A6J1P4J9_BICAN/190-319 AC A0A6J1P4J9.1
#=GS A0A7K8P265_COCCO/357-662 AC A0A7K8P265.1
#=GS A0A2J7Q7Q1_9NEOP/1-204 AC A0A2J7Q7Q1.1
#=GS A0A075B301_ROZAC/395-700 AC A0A075B301.1
#=GS A0A1Y3NSL4_PIRSE/1-74 AC A0A1Y3NSL4.1
#=GS A0A7J8DNK4_MOLMO/366-671 AC A0A7J8DNK4.1
#=GS A0A8C5TBK8_9PASS/363-667 AC A0A8C5TBK8.1
#=GS A0A7J7BT34_9COLE/380-686 AC A0A7J7BT34.1
#=GS W4FD04_APHAT/359-662 AC W4FD04.1
#=GS A0A851RWS5_CERFA/353-658 AC A0A851RWS5.1
#=GS A0A8J4T2Y2_9TREM/318-623 AC A0A8J4T2Y2.1
#=GS A0A8J2SZE5_9STRA/371-684 AC A0A8J2SZE5.1
#=GS A0A7K5QM44_9PASE/353-658 AC A0A7K5QM44.1
#=GS A0A7L1AQP6_GYMTI/353-658 AC A0A7L1AQP6.1
#=GS A0A7K6W8I0_STECA/167-472 AC A0A7K6W8I0.1
#=GS A0A7K7Z6Z9_9PASE/353-658 AC A0A7K7Z6Z9.1
#=GS A0A067R4H8_ZOONE/341-646 AC A0A067R4H8.1
#=GS A0A6J2VPC3_CHACN/367-672 AC A0A6J2VPC3.1
#=GS A0A2V0PFX9_9CHLO/521-611 AC A0A2V0PFX9.1
#=GS S9YII3_CAMFR/335-564 AC S9YII3.1
#=GS A0A8C6XVS3_NAJNA/364-669 AC A0A8C6XVS3.1
#=GS A0A814HJA8_9BILA/459-729 AC A0A814HJA8.1
#=GS A0A7K9UHV8_9AVES/357-662 AC A0A7K9UHV8.1
#=GS A0A0W8CWL7_PHYNI/428-725 AC A0A0W8CWL7.1
#=GS A0A7L1LA08_HIMHI/357-662 AC A0A7L1LA08.1
#=GS G3SN59_LOXAF/401-652 AC G3SN59.1
#=GS A0A6G0I9H3_LARCR/359-664 AC A0A6G0I9H3.1
#=GS K2MKR7_TRYCR/510-815 AC K2MKR7.1
#=GS A0A8B7XL32_ACAPL/459-690 AC A0A8B7XL32.1
#=GS A0A8C3YVM4_9CETA/366-671 AC A0A8C3YVM4.1
#=GS A0A0L0H5L5_SPIPD/505-810 AC A0A0L0H5L5.1
#=GS Q38BR6_TRYB2/400-684 AC Q38BR6.1
#=GS A0A8C3QYT7_9PASS/373-678 AC A0A8C3QYT7.1
#=GS A0A8C4E2H4_DICLA/359-664 AC A0A8C4E2H4.2
#=GS A0A7L1CWF4_9PASS/353-658 AC A0A7L1CWF4.1
#=GS A0A3S0ZNU2_ELYCH/368-673 AC A0A3S0ZNU2.1
#=GS A0A6A4VHL4_AMPAM/415-562 AC A0A6A4VHL4.1
#=GS A0A329SUL2_9STRA/392-695 AC A0A329SUL2.1
#=GS A0A8D0GQ54_SPHPU/355-658 AC A0A8D0GQ54.1
#=GS A0A8K1CHY7_PYTOL/383-688 AC A0A8K1CHY7.1
#=GS A0A7K7AZ15_9AVES/356-661 AC A0A7K7AZ15.1
#=GS A0A7J6RYW6_PEROL/548-833 AC A0A7J6RYW6.1
#=GS A0A8J5XYK9_DIALT/367-672 AC A0A8J5XYK9.1
#=GS A0A093J6V5_DRYPU/352-657 AC A0A093J6V5.1
#=GS A0A8B6GXG0_MYTGA/56-361 AC A0A8B6GXG0.1
#=GS A0A1J4KCL1_9EUKA/300-605 AC A0A1J4KCL1.1
#=GS A0A084VEJ4_ANOSI/378-683 AC A0A084VEJ4.1
#=GS A0A816U4L3_9BILA/518-735 AC A0A816U4L3.1
#=GS A0A7K4LNA5_9AVES/356-661 AC A0A7K4LNA5.1
#=GS G0QVL7_ICHMG/150-252 AC G0QVL7.1
#=GS A0A6I8NDY1_ORNAN/362-653 AC A0A6I8NDY1.1
#=GS A0A7K6GEF5_9PASS/353-658 AC A0A7K6GEF5.1
#=GS A0A6P7U0B0_OCTVU/386-719 AC A0A6P7U0B0.1
#=GS A0A7K6QX23_9PASS/353-658 AC A0A7K6QX23.1
#=GS A0A7K4RHJ4_COLPI/355-660 AC A0A7K4RHJ4.1
#=GS E9ACX3_LEIMA/412-717 AC E9ACX3.1
#=GS B4NAZ6_DROWI/363-668 AC B4NAZ6.1
#=GS A0A7N8XIA1_9TELE/359-664 AC A0A7N8XIA1.1
#=GS A0A835T4G2_CHLIN/367-668 AC A0A835T4G2.1
#=GS A0A699YRK0_HAELA/1-57 AC A0A699YRK0.1
#=GS A0A2Y9JCU5_ENHLU/366-671 AC A0A2Y9JCU5.1
#=GS A0A821P009_9BILA/96-174 AC A0A821P009.1
#=GS A0A7K9N1Y5_9CORV/353-658 AC A0A7K9N1Y5.1
#=GS B3RXZ3_TRIAD/1-80 AC B3RXZ3.1
#=GS W5NGD7_LEPOC/398-697 AC W5NGD7.1
#=GS A0A8B8I631_VANTA/367-674 AC A0A8B8I631.1
#=GS A0A8C3PDM7_CHRPI/395-700 AC A0A8C3PDM7.1
#=GS A0A812PG24_9DINO/5-199 AC A0A812PG24.1
#=GS A0A5J5MT40_MUNRE/363-668 AC A0A5J5MT40.1
#=GS A0A8J6CBQ3_DIALT/370-675 AC A0A8J6CBQ3.1
#=GS A0A1S8W0P6_9FUNG/415-724 AC A0A1S8W0P6.1
#=GS A0A0W8C7I0_PHYNI/384-689 AC A0A0W8C7I0.1
#=GS A0A6J2SY84_DROLE/363-668 AC A0A6J2SY84.1
#=GS A0A8C9HKR2_9PRIM/348-653 AC A0A8C9HKR2.1
#=GS A0A7L3VYK1_MOLAT/353-658 AC A0A7L3VYK1.1
#=GS V5A873_TRYCR/361-671 AC V5A873.1
#=GS A0A7K6LK08_9CORV/353-658 AC A0A7K6LK08.1
#=GS A0A091H1W9_BUCRH/360-665 AC A0A091H1W9.1
#=GS A0A5F8GG46_MONDO/435-740 AC A0A5F8GG46.1
#=GS A0A8J5UY96_9HYME/254-434 AC A0A8J5UY96.1
#=GS A0A5E4AYM9_MARMO/1-214 AC A0A5E4AYM9.1
#=GS A0A5D6Y4G9_9STRA/389-693 AC A0A5D6Y4G9.1
#=GS A0A671U0U8_SPAAU/376-681 AC A0A671U0U8.1
#=GS A0A8B6DMR2_MYTGA/373-678 AC A0A8B6DMR2.1
#=GS A0A0M0K1I6_9EUKA/326-637 AC A0A0M0K1I6.1
#=GS A0A671U2N5_SPAAU/359-664 AC A0A671U2N5.1
#=GS A0A8C8AGH3_9STRI/365-672 AC A0A8C8AGH3.1
#=GS A0A850XAF6_PIACA/348-653 AC A0A850XAF6.1
#=GS A0A821W601_9NEOP/369-674 AC A0A821W601.1
#=GS A0A8C2UL55_CHILA/366-671 AC A0A8C2UL55.1
#=GS A0A507CFI6_9FUNG/449-754 AC A0A507CFI6.1
#=GS A0A6J3I674_SAPAP/366-671 AC A0A6J3I674.1
#=GS C5LMK0_PERM5/1-254 AC C5LMK0.1
#=GS A0A7M7PTN2_STRPU/463-693 AC A0A7M7PTN2.1
#=GS A0A6J0TAR6_9SAUR/366-671 AC A0A6J0TAR6.1
#=GS A0A8B7QSQ9_HIPAR/366-394 AC A0A8B7QSQ9.1
#=GS A0A6P6HDE6_PUMCO/414-719 AC A0A6P6HDE6.1
#=GS A0A8J8SY40_HALGN/222-527 AC A0A8J8SY40.1
#=GS A0A3R7L4Y2_TRYRA/415-684 AC A0A3R7L4Y2.1
#=GS A0A139WBS4_TRICA/380-685 AC A0A139WBS4.1
#=GS A0A2K5RC28_CEBIM/364-669 AC A0A2K5RC28.1
#=GS A0A813STH9_9BILA/402-707 AC A0A813STH9.1
#=GS A0A8C6ZRH0_NOTPE/1-87 AC A0A8C6ZRH0.1
#=GS A0A812MH71_9DINO/20-226 AC A0A812MH71.1
#=GS A0A7M7LRR0_NASVI/380-685 AC A0A7M7LRR0.1
#=GS A0A7L2MJD4_9PASS/353-658 AC A0A7L2MJD4.1
#=GS A0A8C9KHR0_PANTA/366-671 AC A0A8C9KHR0.1
#=GS A0A812QCD2_9DINO/656-733 AC A0A812QCD2.1
#=GS A0A0M0JN86_9EUKA/344-649 AC A0A0M0JN86.1
#=GS A0A6P5BHD5_BOSIN/366-671 AC A0A6P5BHD5.1
#=GS T1G1Z3_HELRO/3-76 AC T1G1Z3.1
#=GS A0A2R6WWL5_MARPO/385-690 AC A0A2R6WWL5.1
#=GS A0A7L0SID6_PODPO/357-662 AC A0A7L0SID6.1
#=GS A0A2I3GIE3_NOMLE/1-83 AC A0A2I3GIE3.1
#=GS X6MLL5_RETFI/340-651 AC X6MLL5.1
#=GS A0A7K7QK48_POEAT/353-658 AC A0A7K7QK48.1
#=GS A0EAT7_PARTE/400-682 AC A0EAT7.1
#=GS A0A7K6XHR1_9PASE/353-658 AC A0A7K6XHR1.1
#=GS V9FG61_PHYPR/384-689 AC V9FG61.1
#=GS A0A4Z2E2I6_9TELE/56-87 AC A0A4Z2E2I6.1
#=GS A0A2I2YJ58_GORGO/1-83 AC A0A2I2YJ58.1
#=GS A0A6A5BHF2_NAEFO/374-679 AC A0A6A5BHF2.1
#=GS A0A7J7QJV6_9CHLO/392-473 AC A0A7J7QJV6.1
#=GS A0A699ZEF7_HAELA/311-443 AC A0A699ZEF7.1
#=GS A0A2P8XXV4_BLAGE/334-458 AC A0A2P8XXV4.1
#=GS M3YZC6_MUSPF/366-671 AC M3YZC6.1
#=GS A0A671K7T0_9TELE/1-68 AC A0A671K7T0.1
#=GS A0A8C7Y936_9TELE/1-74 AC A0A8C7Y936.1
#=GS A0A7K8FH81_9CORV/353-658 AC A0A7K8FH81.1
#=GS K2NV32_TRYCR/414-684 AC K2NV32.1
#=GS A0A1R2CE11_9CILI/381-690 AC A0A1R2CE11.1
#=GS A0A2U3YL51_LEPWE/235-260 AC A0A2U3YL51.1
#=GS A0A7L0X542_TYRSA/352-657 AC A0A7L0X542.1
#=GS A0A673MEI2_9TELE/367-672 AC A0A673MEI2.1
#=GS H3CHN8_TETNG/352-657 AC H3CHN8.1
#=GS C5KU34_PERM5/432-663 AC C5KU34.1
#=GS A0A7J8G6Q4_ROUAE/88-393 AC A0A7J8G6Q4.1
#=GS A0A2K6MIW4_RHIBE/1-83 AC A0A2K6MIW4.1
#=GS A0A7K7LWV1_9PASS/353-658 AC A0A7K7LWV1.1
#=GS A0A6P4FH91_DRORH/224-419 AC A0A6P4FH91.1
#=GS A0A7L0D3P7_9CHAR/357-662 AC A0A7L0D3P7.1
#=GS A0A0L0RZ98_ALLM3/439-745 AC A0A0L0RZ98.1
#=GS A0A2I0TRK9_LIMLA/58-366 AC A0A2I0TRK9.1
#=GS A0A2K5RC18_CEBIM/366-671 AC A0A2K5RC18.1
#=GS A0A1S8WAG6_9FUNG/513-818 AC A0A1S8WAG6.1
#=GS A0A452QCW8_URSAM/366-671 AC A0A452QCW8.1
#=GS A0A6P8RC46_GEOSA/357-662 AC A0A6P8RC46.1
#=GS A0A8D2NMZ7_ZOSLA/362-667 AC A0A8D2NMZ7.1
#=GS A0A2K6RLB5_RHIRO/366-671 AC A0A2K6RLB5.1
#=GS Q4Q0R0_LEIMA/365-670 AC Q4Q0R0.1
#=GS A0A7K4J7C8_GEOCA/357-662 AC A0A7K4J7C8.1
#=GS A0A7L1Z9E5_LEILU/353-658 AC A0A7L1Z9E5.1
#=GS A0A7L2JVH4_CINMU/56-361 AC A0A7L2JVH4.1
#=GS A0A8J6E1X1_9EUKA/435-668 AC A0A8J6E1X1.1
#=GS A0A1X7VG46_AMPQE/387-692 AC A0A1X7VG46.1
#=GS A0A7L3P1K8_9DEND/353-658 AC A0A7L3P1K8.1
#=GS A0A091MBD8_CATAU/362-667 AC A0A091MBD8.1
#=GS A0A094KGX4_ANTCR/362-667 AC A0A094KGX4.1
#=GS A0A8B9XIZ6_BOSMU/1-82 AC A0A8B9XIZ6.1
#=GS V5D614_TRYCR/385-690 AC V5D614.1
#=GS A0A6J3AYV5_VICPA/585-704 AC A0A6J3AYV5.1
#=GS T1H7X9_RHOPR/115-374 AC T1H7X9.1
#=GS A0A670I0B4_PODMU/366-671 AC A0A670I0B4.1
#=GS A0A7K7KUU5_9AVES/357-662 AC A0A7K7KUU5.1
#=GS A0A6J0THK1_9SAUR/412-713 AC A0A6J0THK1.1
#=GS F6SPQ7_MACMU/366-671 AC F6SPQ7.2
#=GS A0A8B9NJC7_9AVES/317-622 AC A0A8B9NJC7.1
#=GS A0A812U4Q4_9DINO/172-469 AC A0A812U4Q4.1
#=GS A0A669PUP8_PHACC/366-671 AC A0A669PUP8.1
#=GS A0A7J6L0W4_PERCH/227-532 AC A0A7J6L0W4.1
#=GS A0A2K5MZG2_CERAT/1-83 AC A0A2K5MZG2.1
#=GS E2B7L2_HARSA/351-537 AC E2B7L2.1
#=GS A0A812BYG8_SEPPH/339-640 AC A0A812BYG8.1
#=GS A0A2P8XXV4_BLAGE/208-337 AC A0A2P8XXV4.1
#=GS A0A8C3QYR1_9PASS/360-665 AC A0A8C3QYR1.1
#=GS A0A3Q3NR69_9LABR/363-668 AC A0A3Q3NR69.1
#=GS A0A091M7Z2_CARIC/362-667 AC A0A091M7Z2.1
#=GS A0A7K5X0I7_9CHAR/357-502 AC A0A7K5X0I7.1
#=GS A0A1Y2CYS3_9FUNG/372-686 AC A0A1Y2CYS3.1
#=GS A0A8J6HW98_TENMO/59-256 AC A0A8J6HW98.1
#=GS A0A2K6MIV0_RHIBE/366-671 AC A0A2K6MIV0.1
#=GS A0A484GSP6_SOUCH/366-671 AC A0A484GSP6.1
#=GS A0A8C8JJZ6_ONCTS/348-614 AC A0A8C8JJZ6.1
#=GS A0A7J5XWJ9_DISMA/118-278 AC A0A7J5XWJ9.1
#=GS A0A8J4P7P4_APTPA/357-662 AC A0A8J4P7P4.1
#=GS A0A0L0HUH8_SPIPD/387-690 AC A0A0L0HUH8.1
#=GS A0A6P8W4R0_GYMAC/358-663 AC A0A6P8W4R0.1
#=GS A0A8B9F109_9PSIT/360-665 AC A0A8B9F109.1
#=GS A0A024FXV5_9STRA/373-675 AC A0A024FXV5.1
#=GS I3KFI6_ORENI/359-664 AC I3KFI6.2
#=GS A0A3Q7PRQ0_CALUR/348-653 AC A0A3Q7PRQ0.1
#=GS A0A482VK54_9CUCU/344-649 AC A0A482VK54.1
#=GS A0A7L4FJ50_9COLU/355-660 AC A0A7L4FJ50.1
#=GS A0A1Y2EST1_9FUNG/106-372 AC A0A1Y2EST1.1
#=GS A0A8C0EKF3_BUBBB/366-673 AC A0A8C0EKF3.1
#=GS A0A8J1L902_XENLA/366-671 AC A0A8J1L902.1
#=GS A0A7J6NAY5_PEROL/171-478 AC A0A7J6NAY5.1
#=GS A0A5E4QCY9_9NEOP/2-145 AC A0A5E4QCY9.1
#=GS A0A2J7ZYL7_9CHLO/317-624 AC A0A2J7ZYL7.1
#=GS A0A2K6CB52_MACNE/348-560 AC A0A2K6CB52.1
#=GS A0A6P8J4W9_ACTTE/369-674 AC A0A6P8J4W9.1
#=GS A0A1X0NJT4_9TRYP/392-696 AC A0A1X0NJT4.1
#=GS A0A8P0NCL9_CANLF/366-671 AC A0A8P0NCL9.1
#=GS A0A2B4S422_STYPI/371-676 AC A0A2B4S422.1
#=GS A0A653CZD3_CALMS/571-663 AC A0A653CZD3.1
#=GS A0A087VF27_BALRE/362-667 AC A0A087VF27.1
#=GS A0A401NUP0_SCYTO/317-616 AC A0A401NUP0.1
#=GS G0QT27_ICHMG/353-657 AC G0QT27.1
#=GS A0A670I0A5_PODMU/366-671 AC A0A670I0A5.1
#=GS A0A226NWN2_COLVI/5-165 AC A0A226NWN2.1
#=GS A0A1Y3NC76_PIRSE/2-168 AC A0A1Y3NC76.1
#=GS A0A024FZZ6_9STRA/384-690 AC A0A024FZZ6.1
#=GS A0A7J6YYM2_9COLE/14-194 AC A0A7J6YYM2.1
#=GS A0A7L0A7C3_9CORV/353-658 AC A0A7L0A7C3.1
#=GS A0A6J1SJ57_FRAOC/1433-1740 AC A0A6J1SJ57.1
#=GS A0A093FNP0_TYTAL/55-360 AC A0A093FNP0.1
#=GS A0A8B6E890_MYTGA/6-222 AC A0A8B6E890.1
#=GS A0CWP0_PARTE/387-670 AC A0CWP0.1
#=GS A0A8C4D0J1_9TELE/357-662 AC A0A8C4D0J1.1
#=GS A0A1Y2HYC2_9FUNG/421-726 AC A0A1Y2HYC2.1
#=GS A0A6J1P378_BICAN/367-672 AC A0A6J1P378.1
#=GS A0A7J6QAR7_PEROL/235-534 AC A0A7J6QAR7.1
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