#=GF ID   DUF759
#=GF AC   PF05537.15
#=GF DE   Borrelia burgdorferi protein of unknown function (DUF759)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_7415 (release 8.0)
#=GF GA   27.00 27.00;
#=GF TC   64.60 64.30;
#=GF NC   25.70 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR008478;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several uncharacterised proteins from
#=GF CC   the Lyme disease spirochete Borrelia burgdorferi.
#=GF SQ   12
#=GS Q9R2Y2_BORBU/1-422   AC Q9R2Y2.1
#=GS Q9S000_BORBU/1-429   AC Q9S000.1
#=GS W6TFW0_9SPIR/1-315   AC W6TFW0.1
#=GS W6TG74_9SPIR/4-244   AC W6TG74.1
#=GS W6TG55_9SPIR/2-108   AC W6TG55.1
#=GS Q9S0I6_BORBU/1-422   AC Q9S0I6.1
#=GS Q9S0F6_BORBU/1-429   AC Q9S0F6.1
#=GS Q9S093_BORBU/1-431   AC Q9S093.1
#=GS Q9S0C6_BORBU/1-422   AC Q9S0C6.1
#=GS W6TG55_9SPIR/89-279  AC W6TG55.1
#=GS W6TFT7_9SPIR/2-165   AC W6TFT7.1
#=GS Q9S049_BORBU/1-422   AC Q9S049.1
Q9R2Y2_BORBU/1-422              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELSRQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNIISNAMSKVGGGLLG....FAKKAVEEDTKTKRTQLLNKAFYGD----------PKEKEGLLKiigGMKGFERDLEKEEFLNQASVFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFDLLKK.SGVGDKYIEDAKMAW....QSGA.QVDLESRITKMMEMFEDFKSFGLTKKVNNAESIQSNLASAEQTLQNLTTTVLDPLLDLINKITNYFKDFAFE...THIINPIINGIKSIF.NLNYFFAK.....L.KSMLPGWMGGDEGAALKKLQEEIQNQDNANS....................................
Q9S000_BORBU/1-429              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELGRQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNIISNAMSKVGGGLLG....FAKKSVEEDTKTKRTKLLNSAFFTDNERNMIMGNKDKNTKGILD...GMKGFERDLEKEEFLHQASAFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFNLLKK.SGVGDKYIEDAKRAW....QGGA.EVDLDSRITKMMEMFEDFKSFGLTKKVNNAESIQSNLASAEQTLSNLTTTVLDPLLNIINWITAKIKNFDFT...KDIINPIINGIKSIF.NLNYFFAK.....L.KSVLPTMFGGDGGEALKKLQEQAENQDNANN....................................
W6TFW0_9SPIR/1-315              ..........md--------------------------------------------------------------------....-----------------------------------------LEYKSLKKQNGIIRRTIRRTgRAVLEI..GKIAVGTALGQVFGTTFQGGIGDAFN....YAKRSIINNANVKKMNVITSRVFKSQEK--------AQLNNILQ...TIPGFNREIDREEFLNYAGILRKDLESLGQNNE..ENLNKAVAFAARLKSTGVVN.DNaSAIAVVSEFLQGKGGSLYNVMGSfSKLTHKYNERGEMEY....DILSlSQALSFRTDTLKKIIDDWNTLEFPKYASTEEKLKDDLIEAEDSFAKTTSELVKPLLKKLSQLATWLQDFTFK...THILDPMIKGLTSFFgNISEWFMKmvkiaL.KQILPDWF-----------------------ykrvfsaddktdkd......................
W6TG74_9SPIR/4-244              ..itlrvfksqe--------------------------------------------------------------------....-------------------------------------------------------------.------..--------------------------....-----------------------------------KAQLNNILQ...TIPGFNREIDREEFLNYAGILRKDLESLGQNNQ..ENLNKAVAFAARLKSTGVVN.DNaSAIAVVSEFLQGKGGSLYNVMDSfNKLTHKYNERGEMEY....DILAsNQALSFRTYTLKKIIDDWNTLKFPKYASDEEKIKDDLIEAEDSFSKTTSELVKPLLAKLSKLATWLQDFTFK...THILDPMIKGLTSFFgNISEWFIKmvkiaL.KQILPTW------------------------tyawffsaddktd.......................
W6TG55_9SPIR/2-108              .........nnt---GFTIKFKGVLDHASTKKSLEKDISILEKVLKPKRTRLDSTEKILKHNLKEKKAELAKINKYEKLKlaeeKRQEKLRIEKQKKLEAAKKRLEKLR------------------------------------.------..--------------------------....--------------------------------------------...---------------------------------..--------------------.--.-----------------------.---------------....----.------------------------------------------------------------------------...---------------.--------.....-.-------------------------------lakdkkqekl..........................
Q9S0I6_BORBU/1-422              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELSRQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNIISNAMSKVGGGLLG....FAKKAVEEDTKTKRTQLLNKAFYGD----------PKEKEGLLKiigGMKGFERDLEKEEFLNQASVFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFDLLKK.SGVGDKYIEDAKMAW....QSGA.QVDLDSRITKMMEMFKDFKSFGLTKKVNNAESIQSNLASAEQTLSNLTTTVLDPLLNIINWITAKIKNFDFT...KDIINPIINGIKSIF.NLNYFFAK.....L.KSVLPTMFGGDGGEALKKLQEQAENQDNANN....................................
Q9S0F6_BORBU/1-429              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELSRQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRHLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALRNIISNAMSKVGGGLLG....FAKKAVEEDTKTKRTKLLNSAFFTDNERNMIMGNKDKNTKGILD...GMKGFERDLEKEEFLNQASVFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFDLLKK.SGVGDKYIEDAKMAW....QSGA.QVDLDSRITKMMEMFKDFKSFGLTKKVNNAESIQSNLASAEQTLQNLTTTVLDPILGLVNKITKYFEGFKFE...THIINPIIDGIKSIF.NLNYFFAK.....L.KSMLPGWMGGDEGAALKKLQEEVQNQDNANN....................................
Q9S093_BORBU/1-431              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELSKQSKFESLR....ERVEKYRLTQTKKLMKQGMGFEKARKEAFKRSLMSDRDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNVIGNAVSKVGGGLIGfmygFAKKAVENKSKEEQLKQLNKVFYSEKERENIL--------GAIK...GMKGFERKLEQQDFLRTSSVLKGHIRELKINDEegENVLNATKLAAMFRSTGLVGdNE.SAVEVVSKILKGELTEAFNILKPiDKFGEKYLEAMKNKLefltQEGG.KKKLRPEIIK--DLIKDISSLNIMGHSDEVALAKSNLAKIEQNLEDVTNNVLMPVIGKISGILEKIMNLNFEqilKQIVDAITGGIKGAF.D-------.....-.-------------------------------giknigsslyntasnvvgntynfatgwinntifgkn
Q9S0C6_BORBU/1-422              ............MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPRNSSLGSTKDIVKNNLSNKKKELSKQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDKDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNIISNAMSKVGGGLLG....FAKKAVEEDTKTKRTQLLNKAFYDD----------PKEKEGLLKiigGMKGFERDLEKEEFLNQASVFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFDLLKK.SGVGDKYIEDAKMAW....QSGA.QVDLESRITKMMEMFEDFKSFGLTKKVNNAESIQSNLASAEQTLQNLTTTVLDPLLDLINKITNYFKDFAFE...THIINPIINGIKSIF.NLNYFFAK.....L.KSMLPGWMGGDEGAALKKLQEEIQNQDNANS....................................
W6TG55_9SPIR/89-279             aakkrleklrla---------------------------------------------------KDKKQEKLRMEE-EKRL....DNIEKFKLQETKRLMSQGMKFRKAKKIAIKRSTMSEKQLMDLEYKTLKKQSGIIR-----R.TGRGIIsmGKIALAATVGGLVAVAAGEAIGSAVD....YARKTIQKNATAKKLSLINSKIFKPEEK--------SKLDKILQ...GIPGFARDIDREEFINYAGILRKDLASLGLNNE..EHL-----------------.--.-----------------------.---------------....----.------------------------------------------------------------------------...---------------.--------.....-.-------------------------------t...................................
W6TFT7_9SPIR/2-165              ........dnaa--------------------------------------------------------------------....-------------------------------------------------------------.------..--------------------------....--------------------------------------------...---------------------------------..--------------------.--.-AISVVSEFLRGKSGPLYDTLRSfHKVFDKYSETKEMEY....NFLSsGQALSFRTETLKKIIDDFDAIELSTYTTKEEKIKNNLGKVEDSFSRISTTVLEPILDCLVKLTNWLEKFNFT...THILDPIKNTLTSFFgNIYEWFTK.....MvKK-----------------------------alkhilwfssaddetdk...................
Q9S049_BORBU/1-422              ............MGDKFTIKFKGILDHAATKKAIEQDISKMGKYLKPKKSSLGSTKDIVKNNLSDKKKELSRQSKFESLR....ERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRRLEYKELAKESKAKSKMLAAS.QGKGLV..AKIAIGSALGNIISNAMSKVGGGLLG....FAKKSVEEDTKTKRTQLLNKAFYGD----------PKEKESLLKiigGMKGFERDLEKEEFLNQASVFKGTLRDLDMLNE..TNLKNAVEFAAMLKSSGAMS.SE.DAVKAVNSVLGGDGSELFDLLKK.SGVGDKYIEDAKRAW....QGGA.EVDLESRITKMMEMFEDFKSFGLTKKANTAEIIQSNLASAEQTLQNLTTTVLDPLLDLINKITNYFKDFTFE...THIIEPIINGIKSIF.NLNYFFAK.....L.KSMLPGWMGGDEGAALKKLQEEIQNQDNANS....................................
#=GC seq_cons                   ...............tFTIKFKGlLDHAuTKKulEpDIShhtKhLKP+popLsSTccIlKpNLp-KKpELu+.sKaEpL+....-RlEKaRLppTKKLhpQGMtFEKARK.Ah+RShMS-+phhcLEYKpLtKpSthhp+hltto.pG+Gll..uKIAlGoALGsllusAhucshGuhls....aAKKulppsspsK+hpllNpthats...........tphpslLp...Gh.GFpR-l-+EEFLN.Aulh+tsLcsLsh.NE..pNLppAVtFAAhLKSoGshs.sp.sAlpsVsphLtGcGupLaslL+p.stls-KY.Ecuchta....p.hu.p.sLp.RhpphhchhcDapohtlsKhssstEpIpsNLupAEpohpplTosVLcPlLshlstlsshhpsFsFp...pcIlsPIIsGlpShF.Nls.aFhK.....L.KphLPsh............................................................
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