#=GF ID   DacZ_A
#=GF AC   PF21754.1
#=GF DE   Probable sensor domain DacZ_A
#=GF AU   Galperin MY;0000-0002-2265-5572
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Galperin M
#=GF GA   28.30 28.30;
#=GF TC   28.80 30.50;
#=GF NC   27.80 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a probable sensor domain found at the N-terminal of
#=GF CC   archaeal diadenylate cyclases, which are typically followed by
#=GF CC   the DAC (Pfam:PF02457) domain. It may consist of four
#=GF CC   alpha-helices and four beta-strands according to structure
#=GF CC   predictions. DacZ_A is distantly related to PK_C (Pfam:PF02887),
#=GF CC   DacZ_N (Pfam:PF19294) and DACZ_P.
#=GF SQ   30
#=GS Q8TSY8_METAC/12-126      AC Q8TSY8.1
#=GS I7J807_METBM/5-99        AC I7J807.1
#=GS D5E7Q6_METMS/6-118       AC D5E7Q6.1
#=GS A2SQQ7_METLZ/7-99        AC A2SQQ7.1
#=GS A0A8J7W852_9EURY/8-99    AC A0A8J7W852.1
#=GS A0A4E0R061_9EURY/6-119   AC A0A4E0R061.1
#=GS W9DQ52_METTI/6-119       AC W9DQ52.1
#=GS A0A483CPK1_9EURY/5-96    AC A0A483CPK1.1
#=GS A0A0X3BJR9_9EURY/5-99    AC A0A0X3BJR9.1
#=GS Q0W0N9_METAR/6-121       AC Q0W0N9.1
#=GS Q12W72_METBU/9-122       AC Q12W72.1
#=GS O28515_ARCFU/60-166      AC O28515.1
#=GS A0A8J7RCF7_9EURY/5-96    AC A0A8J7RCF7.1
#=GS H1Z4I9_9EURY/2-93        AC H1Z4I9.1
#=GS D3S1X1_FERPA/4-110       AC D3S1X1.1
#=GS A0A484F7B3_9EURY/30-144  AC A0A484F7B3.1
#=GS Q8PVY7_METMA/6-120       AC Q8PVY7.1
#=GS A0A1Q6DXG0_9EURY/4-113   AC A0A1Q6DXG0.1
#=GS D2RHE3_ARCPA/4-113       AC D2RHE3.1
#=GS B8GKV2_METPE/5-96        AC B8GKV2.1
#=GS E1RKS7_METP4/6-97        AC E1RKS7.1
#=GS F2KSP0_ARCVS/4-117       AC F2KSP0.1
#=GS A0A2V3JP84_9EURY/6-106   AC A0A2V3JP84.1
#=GS L0KU83_METHD/30-141      AC L0KU83.1
#=GS A0A498GZB8_9EURY/5-96    AC A0A498GZB8.1
#=GS N0BMF9_9EURY/4-117       AC N0BMF9.1
#=GS F7XPG6_METZD/6-119       AC F7XPG6.1
#=GS A0A0E3P1P3_9EURY/6-119   AC A0A0E3P1P3.1
#=GS D7EBG1_METEZ/6-119       AC D7EBG1.1
#=GS D1YYL2_METPS/6-121       AC D1YYL2.1
Q8TSY8_METAC/12-126                 ......i-IAEAAARISQELDAAAIMVS.GDLSFE...GIETGGIPVYYI.....SMRPKSIIDHLVATGkegKSPAKELSDQLNRE.ASGNVDHLQHAAAIEYVLEGPKSG.TIVGVVETRG.SSSIIVHSL-d..
I7J807_METBM/5-99                   .......LMLATACEVAAKIGARAVVSF.VDLIPV...PPGAPDVPIIRV.....QELQLDVLKDL----...---------TMHDI.LEVSERHMMDAAIHIYLRRNLESG.LVVGVFPY--.--AIIIYDIE...
D5E7Q6_METMS/6-118                  .......ILVKSALETATQIKASAIIVS.GNVDRN...-LFGCDLPVYFA.....ANPSRSAVESLIPLDe.eEGRLKQIVNQIQRD.AAVSIEDVENAAAIEQAIGDIKKG.KVVGLVVTDD.SGAVIVHNIS...
A2SQQ7_METLZ/7-99                   .......LLLTAADNLAKTVNALAVISF.LPKE--...EDIVIDTPTVHV.....VDIQPEILRDH----...---------SMVAL.VDYCSNQIIDAVLQYKILANVDSG.TVVAAFPY--.--AILIYDVE...
A0A8J7W852_9EURY/8-99               .......VLMAAAVELAESVDAIAILSF.LDPA--...-PVEADVPIVWV.....KEYQPDLMIKR----...---------NMQEL.LLFCEQHVLDAVVQYHLRTEVSSG.KIIGVFPF--.--AILIYDV-g..
A0A4E0R061_9EURY/6-119              .......TILKTAVKLAEDLESTAIIVS.GNISLE...-GISTDMPVFFS.....SRRSKSIIDHLVSTTkhkEEKIKGIADRVTQQ.ATGKINHIEDISATEYMLGELEEG.LVIGIIETTD.SIAVIVHNLE...
W9DQ52_METTI/6-119                  .......VVVNTAVRLAEELKSTAIIIS.GEADFE...-KPKTSIPVYFA.....SSKQKNIIDHLVASSktkEEKTKEILDKIGQQ.AAGKIEHIESTSAIEFILEEISEG.NIIGIIESKD.SYAIVVHNLE...
A0A483CPK1_9EURY/5-96               .......VLMGAAVEIADEVGAKAIVSF.TRPC--...-TCQAKVPLIWV.....QDLQLDILKDL----...---------SMSEI.VSTCEHHMLDAAIQIYLSHRFEEG.VVVAVFPY--.--AILVYDLE...
A0A0X3BJR9_9EURY/5-99               .......LMLATACEVAAKIGARAVVSF.VDLIPV...PPGAPDVPIIRV.....QELQLDVLKDL----...---------TMHDI.LEVSERHMMDAAIHIYLRRNLESG.LVVGVFPY--.--AIIIYDIE...
Q0W0N9_METAR/6-121                  ......e-VTKAGEELAEKIGATAIIII.SPQARQi.rESLKTRLPVIIArvdgvAARPGDASVDLFTR-...--MTPDVDRESVFL.KVSRIELMSEAIEAAYIQGLIQDR.IVLGIVSIGD.THSVIVVDI-t..
Q12W72_METBU/9-122                  .......ILVKHAIKIAEELCSTAIIVS.GDFDLA...-DIETNIPIYYV.....PRRQKSIIDNLISDSqedEKRLKNILEPMVRE.ATGNTQHIEQAAAIEHIIGELRTG.TIVGIIQTRE.SGAIVTHEV-s..
O28515_ARCFU/60-166                 .......VLVNSALKIAEEYGIERIALI.SKEEFE...-EELEGFEIIQA.....PKKFATILDSMIYYF..eESEEKIIAEKFAQI.YRA----REYISAQMYLKG-FEFG.RAVVVFDTDT.LKGLTIF---epe
A0A8J7RCF7_9EURY/5-96               .......LLVQTATELAEEIGARAVVSF.TQPC--...-TCQAKVPLVWV.....KDLQLDILKDL----...---------SMCEI.LSVCEHHMLDAAVHAYLKEQFEDG.TVVAVFPY--.--AILVFDLE...
H1Z4I9_9EURY/2-93                   .......VMMKSAEKIAEEIGAKAIVSF.MRDI--...-EFESEIPVIKV.....EDLQLDVLKDL----...---------TMHDI.LEISEKHLHDAAVQIYLLKNFAEG.QVVAVFPY--.--ALVIYDID...
D3S1X1_FERPA/4-110                  .......LLIKHAKEIAKAVGAKRIVLL.TDEYVNpenIDDNDEIKIVLS.....PEKYVNAVKNTIS--...------MADSSGFF.EKVLATPGISEFLTNYLQIIGEFG.KSVLVVSVGT.LKGIIVLDAE...
A0A484F7B3_9EURY/30-144             illkdsv------LHLAKLTGAVAVFTF.GNIDTK...SFKDLTIPIIDI.....TQ-IKTIIEKLTYLQhedQFQIQEVSESIRTE.ADKNASLLMSAAAVEYSLGTIECG.IVIGLIRTQN.SYSLVVHSME...
Q8PVY7_METMA/6-120                  .......VIAEAAAHISRELGAAAIMVS.GDLNFE...GIETGEIPVYYI.....SMRPKSIIDHLVATSkdgKSPVKELGDQLTRE.ASGNVEYVQHAAAIEYALEGPKNG.IVVGVIETRG.SSSIIVHNLD...
A0A1Q6DXG0_9EURY/4-113              ......k-LIEKSSEIAEEIDASALIVIpGEKEIEgllEEKEYSFPIFIV.....TSPEKKYSGTH----...----EEFKISARGE.TQNFAKQFQDAVMMAYVKGKVDVGdKIVGVGAIEDeATGILVYNV-y..
D2RHE3_ARCPA/4-113                  .......TLVKLAKELARKINTDKIVLI.TKSDFD...-FEDDEFSIFVA.....PKRFVTMLESMFYT-...-IAEEELSGKDVFErALAFLQVSEITPLQMYLRGIELKG.GVVGVLDLDI.LKGLMVIDLE...
B8GKV2_METPE/5-96                   .......LMLRKGIELAEAIHAVGVIAF.LPRT--...-PYSSSVEVFWA.....DEGYLDIWKDL----...---------TMHQA.LESVRQHIRDAAVQVSLEKDLTEG.TLVGVFSH--.--AILVYSIE...
E1RKS7_METP4/6-97                   .......LMMQTAADLAAKTGAKAIVSF.LSPL--...-EFESGIPVIWV.....EDLQLDVLKDL----...---------TMHDI.LEVSEKHLNDAAVQIYLAKEFEEG.IVVGVFPH--.--ALITFDIK...
F2KSP0_ARCVS/4-117                  ......f-LLDKAIEMARKVDAKAIVVI.SDEEVR...EKVVEDIIVFVA.....PKSYTTLLESAMCSLe.eVSQDNLIGKELSER.LLMLTQAKDYVSTMLYFKGIGLDG.SAVGVISVES.LKGIVVIDL-g..
A0A2V3JP84_9EURY/6-106              ......a-IIQSVVDIAECIHASAILLP.DSYTSE..rIGIETEIPVMVM.....PRQASDLLYRIIP--...--------NHVEKE.EAVLHARIQGIAVAGYLKGAI-SG.VVVGVIDGPS.FDSIIVYD--p..
L0KU83_METHD/30-141                 .......VFIETAVKLAEGLGSSAIILA.GDFCFV...-DVITDIPIYHA.....FSDQKELIDHLIFST..gEKGVSTFTNKMIDK.SYHKLEELENISSIEHVLGNISGG.TVVGIVGSID.SCAIVVHDLN...
A0A498GZB8_9EURY/5-96               .......TMLEAARQVAASVNAKAIVSF.TEPR--...-EFASEVPVIWV.....QELQLDVLKDL----...---------TMHDI.LEVSERHMLDATVQIYLSRRFESG.LVVGVFPY--.--AIILYDIE...
N0BMF9_9EURY/4-117                  .......LLLEKAVEIAKKLNEDHIFVI.SHEFYD...IDDFNGVKIYNI.....PKKFSNYLESMLFSFekdYDAEKVLGSLIEKS.LIA-QNILEYVSSLSFLKNIPLSE.NCIMLIDLES.YKGLIVSNQ-k..
F7XPG6_METZD/6-119                  .......IIIKNAVNLARELNACAIIVF.GDIPIE...-GNETSIPIYSI.....SKKPKDFIKYLISSSvekTKGDTDLSSQLVQE.CSGKIEHLEKVAAIEHFMDQIRDG.IVIGVIETFD.STSIIIHNIK...
A0A0E3P1P3_9EURY/6-119              .......VIVEAATRIARELDAAAIMVS.GELSFE...-GIETDIPIYYT.....SMRPKSIIDHLVATGkegKGAARELIDQLSRE.SAGNIEHLQNAVAIEYVLDELKKG.IVIGIIETRD.SSSIIVHNLD...
D7EBG1_METEZ/6-119                  .......TIVKTALDLAEKLEAEAIIVS.GDIEIK...-DLTTSLPVYFA.....HRRPKSIIDYLVSTSseqQERGKEIADKITQE.VAGNTKNVENVAAIEHLLGELERG.VVVGIVETRD.SSSIIVHDLS...
D1YYL2_METPS/6-121                  ......e-VVASALGLARDLDAGSIILI.SPEASAi.rKELDTDIPIIIA.....RILGGRGDGDDIFVDi.mSKLPKNIGKSSLFL.KVSRIELMSEAVEVAYIKGMIPNK.VTVGIVSIGD.INSIVVMDIN...
#=GC seq_cons                       .......lllcsAhclAcclsApAIllh.sc.sht....thpsclPlhhs.....sch.tsllccLh............h.pphpp..hpsptcclpsAushtYlhsplcsG.hVVGVlsh.s...uIlVa-lp...
//