#=GF ID Dec-1
#=GF AC PF04624.18
#=GF DE Dec-1 repeat
#=GF PI DEC-1_REPEAT;
#=GF AU Kerrison ND;0000-0002-1471-953X
#=GF SE DOMO:DM04594;
#=GF GA 22.00 22.00;
#=GF TC 25.20 22.20;
#=GF NC 18.80 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Repeat
#=GF RN [1]
#=GF RM 1699826
#=GF RT Multiple proteins are produced from the dec-1 eggshell gene in
#=GF RT Drosophila by alternative RNA splicing and proteolytic cleavage
#=GF RT events.
#=GF RA Waring GL, Hawley RJ, Schoenfeld T;
#=GF RL Dev Biol 1990;142:1-12.
#=GF RN [2]
#=GF RM 8350348
#=GF RT Evolution of the dec-1 eggshell locus in Drosophila. II.
#=GF RT Intraspecific DNA sequence analysis reveals length mutations in
#=GF RT a repetitive region in D. melanogaster.
#=GF RA Andersson S, Lambertsson A;
#=GF RL J Mol Evol 1993;36:536-544.
#=GF DR INTERPRO; IPR006718;
#=GF DR SO; 0001068; polypeptide_repeat;
#=GF CC The defective chorion-1 gene (dec-1) in Drosophila encodes
#=GF CC follicle cell proteins necessary for proper eggshell assembly.
#=GF CC Multiple products of the dec-1 gene are formed by alternative
#=GF CC RNA splicing and proteolytic processing [1]. Cleavage products
#=GF CC include S80 (80 kDa) which is incorporated into the eggshell,
#=GF CC and further proteolysis of S80 gives S60 (60 kDa). This repeat
#=GF CC is usually found in 12 copies in the central region of the
#=GF CC protein. Its function is unknown. Length polymorphisms of Dec-1
#=GF CC have been observed in wild-type strains, and are caused by
#=GF CC changes in the numbers of the first five repeats [2].
#=GF SQ 77
#=GS DEC11_DROME/545-571 AC P18169.2
#=GS M9NEY9_DROME/623-649 AC M9NEY9.1
#=GS M9NEY9_DROME/571-597 AC M9NEY9.1
#=GS DEC13_DROME/652-681 AC P18171.2
#=GS M9NG31_DROME/580-606 AC M9NG31.1
#=GS DEC13_DROME/623-649 AC P18171.2
#=GS M9NEA7_DROME/502-528 AC M9NEA7.1
#=GS M9NEY9_DROME/493-519 AC M9NEY9.1
#=GS DEC12_DROME/545-571 AC P18170.2
#=GS M9NG31_DROME/502-528 AC M9NG31.1
#=GS A0A6P4EXT8_DRORH/717-736 AC A0A6P4EXT8.1
#=GS DEC11_DROME/519-545 AC P18169.2
#=GS DEC12_DROME/733-759 AC P18170.2
#=GS A0A0Q9XHG4_DROMO/576-603 AC A0A0Q9XHG4.1
#=GS B3MRA8_DROAN/642-666 AC B3MRA8.2
#=GS B4MAG1_DROVI/594-618 AC B4MAG1.2
#=GS A0A0Q9XHG4_DROMO/549-575 AC A0A0Q9XHG4.1
#=GS M9NG31_DROME/635-664 AC M9NG31.1
#=GS B4NCW6_DROWI/752-774 AC B4NCW6.2
#=GS DEC13_DROME/519-545 AC P18171.2
#=GS A0A0Q9WTZ3_DROWI/752-774 AC A0A0Q9WTZ3.1
#=GS B3MRA8_DROAN/591-622 AC B3MRA8.2
#=GS DEC12_DROME/597-623 AC P18170.2
#=GS DEC12_DROME/571-597 AC P18170.2
#=GS B4MAG1_DROVI/547-569 AC B4MAG1.2
#=GS DEC12_DROME/652-681 AC P18170.2
#=GS M9NEA7_DROME/635-664 AC M9NEA7.1
#=GS A0A6P4EXT8_DRORH/663-689 AC A0A6P4EXT8.1
#=GS M9NG31_DROME/554-580 AC M9NG31.1
#=GS M9NEY9_DROME/652-681 AC M9NEY9.1
#=GS M9NEY9_DROME/545-571 AC M9NEY9.1
#=GS B3MRA8_DROAN/689-714 AC B3MRA8.2
#=GS M9NEA7_DROME/528-554 AC M9NEA7.1
#=GS DEC11_DROME/571-597 AC P18169.2
#=GS B4IL40_DROSE/570-596 AC B4IL40.1
#=GS B4IL40_DROSE/544-570 AC B4IL40.1
#=GS DEC13_DROME/733-759 AC P18171.2
#=GS B3MRA8_DROAN/622-643 AC B3MRA8.2
#=GS DEC13_DROME/597-623 AC P18171.2
#=GS B4MAG1_DROVI/755-774 AC B4MAG1.2
#=GS M9NEA7_DROME/476-502 AC M9NEA7.1
#=GS DEC11_DROME/652-681 AC P18169.2
#=GS B4L6A5_DROMO/639-661 AC B4L6A5.2
#=GS M9NG31_DROME/606-632 AC M9NG31.1
#=GS B4IL40_DROSE/599-628 AC B4IL40.1
#=GS A0A0Q9XHG4_DROMO/639-661 AC A0A0Q9XHG4.1
#=GS DEC13_DROME/545-571 AC P18171.2
#=GS M9NEA7_DROME/716-742 AC M9NEA7.1
#=GS DEC11_DROME/493-519 AC P18169.2
#=GS M9NG31_DROME/476-502 AC M9NG31.1
#=GS M9NEY9_DROME/733-759 AC M9NEY9.1
#=GS B4IL40_DROSE/669-695 AC B4IL40.1
#=GS DEC12_DROME/623-649 AC P18170.2
#=GS M9NG31_DROME/716-742 AC M9NG31.1
#=GS DEC12_DROME/519-545 AC P18170.2
#=GS DEC11_DROME/623-649 AC P18169.2
#=GS A0A6P4ETS0_DRORH/663-689 AC A0A6P4ETS0.1
#=GS M9NEA7_DROME/554-580 AC M9NEA7.1
#=GS M9NEY9_DROME/597-623 AC M9NEY9.1
#=GS B3MRA8_DROAN/556-577 AC B3MRA8.2
#=GS A0A6P4ETS0_DRORH/717-736 AC A0A6P4ETS0.1
#=GS B4IL40_DROSE/518-544 AC B4IL40.1
#=GS B4MAG1_DROVI/620-644 AC B4MAG1.2
#=GS M9NEY9_DROME/519-545 AC M9NEY9.1
#=GS M9NEA7_DROME/580-606 AC M9NEA7.1
#=GS B4L6A5_DROMO/576-603 AC B4L6A5.2
#=GS DEC11_DROME/733-759 AC P18169.2
#=GS M9NEA7_DROME/606-632 AC M9NEA7.1
#=GS A0A6J2TYD7_DROLE/907-935 AC A0A6J2TYD7.1
#=GS B4MAG1_DROVI/571-593 AC B4MAG1.2
#=GS DEC12_DROME/493-519 AC P18170.2
#=GS DEC13_DROME/571-597 AC P18171.2
#=GS DEC11_DROME/597-623 AC P18169.2
#=GS M9NG31_DROME/528-554 AC M9NG31.1
#=GS DEC13_DROME/493-519 AC P18171.2
#=GS B4IL40_DROSE/492-518 AC B4IL40.1
#=GS B4MAG1_DROVI/711-738 AC B4MAG1.2
DEC11_DROME/545-571 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEY9_DROME/623-649 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
M9NEY9_DROME/571-597 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC13_DROME/652-681 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
M9NG31_DROME/580-606 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC13_DROME/623-649 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
M9NEA7_DROME/502-528 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEY9_DROME/493-519 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC12_DROME/545-571 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NG31_DROME/502-528 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
A0A6P4EXT8_DRORH/717-736 .QNPIMM...QQRQWSEDAQ.KV..QQ-....------....
DEC11_DROME/519-545 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC12_DROME/733-759 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
A0A0Q9XHG4_DROMO/576-603 .QNPMMM...--RQWAEGEA.KAkeQQQ...sQQMLQQ....
B3MRA8_DROAN/642-666 .QNPTMM...QQRQWSEDQA.K-..-QQ....QHMMQQ....
B4MAG1_DROVI/594-618 .QNSMMM...--RQWTEDQA.KA..QQQ....NTMMMQ....
A0A0Q9XHG4_DROMO/549-575 .QNPMMM...--RQWAEGEA.KAkeQQQ....SQQMQQ....
M9NG31_DROME/635-664 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
B4NCW6_DROWI/752-774 .QNPMMM...QQRQMAEEQA.KI..QQI....Q-----m...
DEC13_DROME/519-545 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
A0A0Q9WTZ3_DROWI/752-774 .QNPMMM...QQRQMAEEQA.KI..QQI....Q-----m...
B3MRA8_DROAN/591-622 .QNNMMM..qQQRQWSEEQA.KI..QQEeqakQQAIQQ....
DEC12_DROME/597-623 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC12_DROME/571-597 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
B4MAG1_DROVI/547-569 .QNDMMM...--RQWTEDKA.KA..Q--....QQMMQQ....
DEC12_DROME/652-681 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
M9NEA7_DROME/635-664 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
A0A6P4EXT8_DRORH/663-689 .ENPQTM...QQRQWLEEQA.KI..QQQ....QQQVQQ....
M9NG31_DROME/554-580 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEY9_DROME/652-681 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
M9NEY9_DROME/545-571 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
B3MRA8_DROAN/689-714 .QGPMMM...-QRQWAEEEA.KA..LQD....QQTMQQ....
M9NEA7_DROME/528-554 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC11_DROME/571-597 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
B4IL40_DROSE/570-596 .QNPMMM...QQRQWAEDQA.KV..QHD....QQMAQQ....
B4IL40_DROSE/544-570 .QNPMMM...QQRQWTEDQA.KI..QQN....QQQIQQ....
DEC13_DROME/733-759 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
B3MRA8_DROAN/622-643 .QNNMMM..qQQRQWSEEQA.KI..QQN....------....
DEC13_DROME/597-623 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
B4MAG1_DROVI/755-774 .------...QQRQWTEEQA.KA..QQP....QQM---se..
M9NEA7_DROME/476-502 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC11_DROME/652-681 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
B4L6A5_DROMO/639-661 .ENAQMM...--RQWSEEQA.KA..QQQ....QQQM--....
M9NG31_DROME/606-632 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
B4IL40_DROSE/599-628 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ....
A0A0Q9XHG4_DROMO/639-661 .ENAQMM...--RQWSEEQA.KA..QQQ....QQQM--....
DEC13_DROME/545-571 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEA7_DROME/716-742 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
DEC11_DROME/493-519 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NG31_DROME/476-502 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEY9_DROME/733-759 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
B4IL40_DROSE/669-695 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
DEC12_DROME/623-649 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
M9NG31_DROME/716-742 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
DEC12_DROME/519-545 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC11_DROME/623-649 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
A0A6P4ETS0_DRORH/663-689 .ENPQTM...QQRQWLEEQA.KI..QQQ....QQQVQQ....
M9NEA7_DROME/554-580 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEY9_DROME/597-623 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
B3MRA8_DROAN/556-577 .QSPMMM...QQRQWSEEQT.KI..QQE....R-----....
A0A6P4ETS0_DRORH/717-736 .QNPIMM...QQRQWSEDAQ.KV..QQ-....------....
B4IL40_DROSE/518-544 .QNPMMM...QQRQWSEEQA.KI..QQN....PQQIQQ....
B4MAG1_DROVI/620-644 .QNPMMM...--RQWTEDQA.KA..QQQa.kdQQM---....
M9NEY9_DROME/519-545 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NEA7_DROME/580-606 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
B4L6A5_DROMO/576-603 .QNPMMM...--RQWAEGEA.KAkeQQQ...sQQMLQQ....
DEC11_DROME/733-759 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ....
M9NEA7_DROME/606-632 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ....
A0A6J2TYD7_DROLE/907-935 .ENPMLM...QQRQWAEGQAvKA..LHK...qRQQMQQ....
B4MAG1_DROVI/571-593 p-NPMMM...--RQWTEEQM.KA..HQQ....------ardr
DEC12_DROME/493-519 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC13_DROME/571-597 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC11_DROME/597-623 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ....
M9NG31_DROME/528-554 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
DEC13_DROME/493-519 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ....
B4IL40_DROSE/492-518 .QNPMMM...EQRQWSEEQA.KI..QQN....QQQIQQ....
B4MAG1_DROVI/711-738 .QNPMMM...--RQWTEDQA.KA..QQQa.kaQQEMQQ....
#=GC seq_cons .QNPMMM...QQRQWSEEQA.KI..QQs....QQ.hQQ....
//
