#=GF ID   Defb50
#=GF AC   PF17546.6
#=GF DE   Beta defensin 50
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   PRODOM:PD935867
#=GF GA   27.00 27.00;
#=GF TC   28.70 126.90;
#=GF NC   25.50 17.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   24204287
#=GF RT   Partial deletion of chromosome 8 beta-defensin cluster confers
#=GF RT   sperm dysfunction  and infertility in male mice.
#=GF RA   Zhou YS, Webb S, Lettice L, Tardif S, Kilanowski F, Tyrrell C,
#=GF RA   Macpherson H, Semple F, Tennant P, Baker T, Hart A, Devenney P,
#=GF RA   Perry P, Davey T, Barran P, Barratt CL, Dorin JR;
#=GF RL   PLoS Genet. 2013;9:e1003826.
#=GF DR   INTERPRO; IPR035193;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Beta-defensin are small cationic antimicrobial peptides. Family
#=GF CC   members such as beta-defensin 50 (Defb50) has poor antimicrobial
#=GF CC   activity in its oxidised form, but this improves under reduced
#=GF CC   conditions [1].
#=GF SQ   3
#=GS A0A8C6G7P5_MUSSI/24-73  AC A0A8C6G7P5.1
#=GS DFB50_MOUSE/24-73       AC Q6TU36.1
#=GS DFB50_RAT/24-73         AC Q30KJ2.1
A0A8C6G7P5_MUSSI/24-73             HPGTFHVRIKCMPKMAAVFGDNCSFYSSMGDLCNNTKSVCCMVPVRMDNI
DFB50_MOUSE/24-73                  HPGTFHVRIKCMPKMTAVFGDNCSFYSSMGDLCNNTKSVCCMVPVRMDNI
DFB50_RAT/24-73                    HPGTVHVRFKCIPKIAAVFGDNCPFYGNVDGLCNDKKSVCCMVPVRLDNI
#=GC seq_cons                      HPGTFHVRIKCMPKMAAVFGDNCSFYSSMGDLCNNTKSVCCMVPVRMDNI
//