#=GF ID   DegQ
#=GF AC   PF08181.15
#=GF DE   DegQ (SacQ) family
#=GF AU   Lee SC;0000-0002-0504-0859
#=GF SE   Short protein clustering
#=GF GA   22.00 22.00;
#=GF TC   22.40 23.10;
#=GF NC   21.90 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1688843
#=GF RT   Signal transduction pathway controlling synthesis of a class of
#=GF RT   degradative enzymes in Bacillus subtilis: expression of the
#=GF RT   regulatory genes and analysis of mutations in degS and degU. 
#=GF RA   Msadek T, Kunst F, Henner D, Klier A, Rapoport G, Dedonder R; 
#=GF RL   J Bacteriol 1990;172:824-834.
#=GF DR   INTERPRO; IPR012554;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of the DegQ (formerly sacQ) regulatory
#=GF CC   peptides. The DegQ family of peptides control the rates of
#=GF CC   synthesis of a class of both secreted and intracellular
#=GF CC   degradative enzymes in Bacillus subtilis. DegQ is 46 amino acids
#=GF CC   long and activates the synthesis of degradative enzymes.  The
#=GF CC   expression of this peptide was shown to be subjected both to
#=GF CC   catabolite repression and DegS-DegU-mediated control. Thus
#=GF CC   allowing an increase in the rate of synthesis of degQ under
#=GF CC   conditions of nitrogen starvation [1].
#=GF SQ   14
#=GS A0A176J396_9BACI/1-46   AC A0A176J396.1
#=GS A0A179T1Z2_9BACI/1-46   AC A0A179T1Z2.1
#=GS A0A084GKF2_METID/1-46   AC A0A084GKF2.1
#=GS A0A4S4C0Q9_9BACI/1-46   AC A0A4S4C0Q9.1
#=GS A0A268E1V7_9BACI/1-46   AC A0A268E1V7.1
#=GS A8FGX9_BACP2/1-46       AC A8FGX9.1
#=GS DEGQ_BACLD/1-46         AC P69889.1
#=GS A0A7X2M0S5_9BACI/1-46   AC A0A7X2M0S5.1
#=GS A0A1L3MNF8_9BACI/1-46   AC A0A1L3MNF8.1
#=GS A0A0M4FRX5_9BACI/1-46   AC A0A0M4FRX5.1
#=GS A0A163ZQU7_9BACI/1-46   AC A0A163ZQU7.1
#=GS A0A2C1KUR4_9BACI/1-46   AC A0A2C1KUR4.1
#=GS DEGQ_BACSU/1-46         AC Q99039.1
#=GS A0A1Y1UYB5_9FUNG/22-47  AC A0A1Y1UYB5.1
A0A176J396_9BACI/1-46              ......MTQHKIEELTQILHQLEKEIRETKQSLQSINKSIDKYDKYAY.VKVS.
A0A179T1Z2_9BACI/1-46              ......MDQQKIEEMTKLLLKLEQEIKETKESLHSINKSIDKYDKYAF.LNVS.
A0A084GKF2_METID/1-46              ......MKKHNIEEITQLLKRLEKEIQETKQSLRMINKSIDKYDKYSF.INVS.
A0A4S4C0Q9_9BACI/1-46              ......MDQQKIDEMTELLIKIEQDIKETKESLRCINRSIDKYDKYAI.LNVS.
A0A268E1V7_9BACI/1-46              ......MDQQKIEEITEMLLKLEKEINETKASLQNINKSIDKYDKYAY.LNVS.
A8FGX9_BACP2/1-46                  ......MEKYEIEELKQLLWKLENEIRETTASLHNINKSIDQYDKYEY.VKIS.
DEGQ_BACLD/1-46                    ......MEKQQIEELKQLLWRLENEIRETKDSLRKINKSIDQYDKYTY.LKTS.
A0A7X2M0S5_9BACI/1-46              ......MNKHTIEEMALLLERLEEEIQETKKSLHSINNSIDKYDKYTY.LKVS.
A0A1L3MNF8_9BACI/1-46              ......MDQQKIEEMTQKLLQIEKELRETKQSLLSINKSIDKYDKYSI.INVS.
A0A0M4FRX5_9BACI/1-46              ......MNQYNIEELKQLLSKLETDIKETNNSLRMINKSIDKYDKYAY.VKIS.
A0A163ZQU7_9BACI/1-46              ......MNHQEIEKINKIFLMLERELDETKKALDNINKSIDKYDKYQY.TKI-v
A0A2C1KUR4_9BACI/1-46              ......MNQQKIDEMTQLLLKIEQELKESKESLQLINKSIDKYDKFAF.LNVS.
DEGQ_BACSU/1-46                    ......MEK-KLEEVKQLLFRLELDIKETTDSLRNINKSIDQLDKYNYaMKIS.
A0A1Y1UYB5_9FUNG/22-47             nlksvr---------------------------RKVNKSIDFFDKYKYcLKCS.
#=GC seq_cons                      ......MsppcIEEhspLLh+LEpEI+ETKpSL+sINKSIDKYDKYsY.lplS.
//