#=GF ID   Desmo_N
#=GF AC   PF06771.15
#=GF DE   Viral Desmoplakin N-terminus
#=GF PI   1111; Desmo_N-term; 
#=GF AU   Vella Briffa B;0000-0003-4380-1783
#=GF SE   Pfam-B_3693 (release 10.0)
#=GF GA   25.00 25.00;
#=GF TC   25.80 32.00;
#=GF NC   24.40 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11781580
#=GF RT   Deconstructing desmoplakin. 
#=GF RA   Hatsell S, Cowin P; 
#=GF RL   Nat Cell Biol 2001;12:270-272.
#=GF DR   INTERPRO; IPR009615;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family represents the N-terminus of viral desmoplakin.
#=GF CC   Desmoplakin is a component of mature desmosomes, which are the
#=GF CC   main adhesive junctions in epithelia and cardiac muscle.
#=GF CC   Desmoplakin is also essential for the maturation of adherens
#=GF CC   junctions [1]. Note that many family members are hypothetical.
#=GF SQ   14
#=GS A5IZV4_9BBAC/4-83        AC A5IZV4.1
#=GS Q9J845_9ABAC/8-94        AC Q9J845.1
#=GS A0A346TQ30_9ABAC/8-94    AC A0A346TQ30.1
#=GS Q0IL36_NPVLS/14-103      AC Q0IL36.1
#=GS I3XMC2_NPVMB/9-97        AC I3XMC2.1
#=GS A0A0E3Z620_9ABAC/10-103  AC A0A0E3Z620.1
#=GS AC66_NPVAC/6-95          AC P41467.1
#=GS Q8B9I6_NPVR1/6-95        AC Q8B9I6.1
#=GS Q91BW5_9ABAC/13-103      AC Q91BW5.1
#=GS Q91EU3_GVCPM/24-108      AC Q91EU3.1
#=GS Q462B0_9ABAC/7-91        AC Q462B0.1
#=GS Q7TLT4_NPVCF/2-77        AC Q7TLT4.1
#=GS K4EQF4_9BBAC/8-101       AC K4EQF4.1
#=GS Q1A4K5_GVCF/8-90         AC Q1A4K5.1
A5IZV4_9BBAC/4-83                   ..RYRGVDINQNTVNNLIRTIVNQHGPSST---------DCDSRIRSI---LFSHRPDLIK.KLSNLPTESLLI----.RCLQDNNK.....KEISYNYNYN----ttn.......................
Q9J845_9ABAC/8-94                   ..KYKNTDVSASTVQNLLQTI-------NSMSQRCRGQANTEDVLQRVRSIILMHRPHLA-.NRIDLQ-LPELTMEAL.MP-NSTNA.....SQITHNFNYKYDYN..........................
A0A346TQ30_9ABAC/8-94               ..KYKNTDVSASTVQNLLQTI-------NSMSQRCRGQANTDDVLQRVRSIILMYRPHLA-.NRIDLQ-LPELTMEAL.MP-NSTNA.....NQITHNFNYKYDYN..........................
Q0IL36_NPVLS/14-103                 ..RYKGTDINAATVQNLLRTI-------NTMSKRTKRQSATDDTLTKIRSIIGVYRPNLV-.NRTNLSVTELLIEALA.NPYGGGGV....pNQITHNFNYKYDYN..........................
I3XMC2_NPVMB/9-97                   ..RYKNTDVSANTVHNLLQTI-------NNMSQRSKNQAYTDEILDRVRSIILVYRPHLIN.RS-DLQV-PELVMEALkPDSANSMP.....HAITHNFNYKYDYN..........................
A0A0E3Z620_9ABAC/10-103             ..KYMNMDVNASTIKNLLQTI-------NTMSRQCKKQRANNESLERIRSIIYSYRPDMKM.RGVDLPVPD-LVMETF.ALMGPHGApnslpNQITHNFNYKYDYN..........................
AC66_NPVAC/6-95                     ..KYGGTDVNTRTVHDLLNTI-------NTMSARIKTLERYEHALREIHKVVVILKPSANT.HSFEPDALPALIMQFL.SDFAGRDI.....NTLTHNINYKYDYN..........................
Q8B9I6_NPVR1/6-95                   ..KYGGTDVNTRTVHDLLNTI-------NTMSARIKTLERYEHALREIHKVVVILKPSANT.HSFEPDALPALIMQFL.SDFAGRDI.....NTLTHNINYKYDYN..........................
Q91BW5_9ABAC/13-103                 ..KYKNTDVNSGTVQSLLRTI-------NSMSQRCKSLDATEDILQRIRSIIVLYRPYLID.R-HDLQV-PELIIEAL.ASPRHHDQp..mhSQITHNYNYKYDYN..........................
Q91EU3_GVCPM/24-108                 ..RYKGVDVTPHTFNNLIKTITNHRSISNTSSSK----NDFEEKIRDI---ILAFNPSLKK.NSADMTTEHLLI----.SSLKVGDK.....KEVTHNYNYN-KWG..........................
Q462B0_9ABAC/7-91                   ..KYKNTEVNADTVQNLLRTI-------NTMSQRCKTQSSTDDVLQRVRSIILLHRPDLIS.RVDDLQI-PELV----.TEALIPSS.....NQITHNFNYKYDYN..........................
Q7TLT4_NPVCF/2-77                   qr-------------NLLSTI-------NSMSARIKALERYEHALREIHKVILVMRPGFNL.QVLDPDAMPALIVQFF.SDLTDR--.....N-TTHNINYRYDYN..........................
K4EQF4_9BBAC/8-101                  ..RYKGVDVTPKTFENLIKTVAQYG--TAVGSSK----TEYDRRIRGI---ILNFCPNLIG.SSANMSTEHLLM-RVL.SRH-----.....--------------mhtknvvdnsdddddddendnymhky
Q1A4K5_GVCF/8-90                    .n-YRGVNVTPYTFNNLIKTIANYKSVSNISSSK----SDYDERIRGI---ILACNPALKKdNTSSMTTEHMLI----.TSLK---K.....NDITHTYNYN-TWN..........................
#=GC seq_cons                       ..+Y+ssDVsspTVpNLLpTI.......NoMSpRh+t.ssh--tLccI+plIlhaRPsLht.psh-hss.s.Ll.phh.sshtspsh.....spITHNaNYKYDYN..........................
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