#=GF ID   Dicty_REP
#=GF AC   PF05086.16
#=GF DE   Dictyostelium (Slime Mold) REP protein
#=GF PI   Dict_REP; 
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_6278 (release 7.7)
#=GF GA   21.00 21.00;
#=GF TC   21.20 21.00;
#=GF NC   20.90 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10366530
#=GF RT   Mechanism of action of the Rep protein from the Dictyostelium
#=GF RT   Ddp2 plasmid family. 
#=GF RA   Shammat IM, Welker DL; 
#=GF RL   Plasmid 1999;41:248-259.
#=GF DR   INTERPRO; IPR007778;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of REP proteins from Dictyostelium (Slime
#=GF CC   molds). REP protein is likely involved in transcription
#=GF CC   regulation and control of DNA replication, specifically
#=GF CC   amplification of plasmid at low copy numbers. The formation of
#=GF CC   homomultimers may be required for their regulatory activity [1].
#=GF SQ   9
#=GS A0A2N5SJG4_9BASI/3-183    AC A0A2N5SJG4.1
#=GS A0A813DDD3_POLGL/3-114    AC A0A813DDD3.1
#=GS A0A834NT35_VESGE/1-149    AC A0A834NT35.1
#=GS A0A4T0X4U8_9ASCO/80-192   AC A0A4T0X4U8.1
#=GS F0Z7Z9_DICPU/4-179        AC F0Z7Z9.1
#=GS A0A1I7SX44_BURXY/5-220    AC A0A1I7SX44.1
#=GS A0A8J4Q3F4_9MYCE/273-369  AC A0A8J4Q3F4.1
#=GS F1A0F2_DICPU/1-877        AC F1A0F2.1
#=GS A0A8H8NDZ1_9AGAM/75-266   AC A0A8H8NDZ1.1
A0A2N5SJG4_9BASI/3-183               ..............hplspneq------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....---------------------------------------------E.............GNEEQDNKTESEENNNNKQNQREREGKNQGITT..TTTTTTTTTETPTRKRLARD-DTLKQHLNPSTRPNTNNSRSSSyhhh...........tpkqQ-----------------------.............--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------tftislsdqphliptktklltelktatqqldqnhleslmlslirelssklnqsqhdlktsqleltglknllintysvgsgeierclvr
A0A813DDD3_POLGL/3-114               ...............tcmqltc------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----------------MLEGICHGKKNNDNNNINNYLNHNSNNNNN.............HDNNNKEATRSAAQIKKRKTQQQQQQQQQTTTT..TTTTTTTTTTVGHKPSRMISDPHLENEKI--------------...................------------------------.............--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------avgekhivqptri...........................................................................
A0A834NT35_VESGE/1-149               ....................mt------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----------------------------------------------.............---------------------------TTTTTT..TTTTTTTTTIRRVNQRTYFNAVAIAGSPRITAKDVEEEEAEDE...................EEEGDDDDDDDDDDDDDDDDDDVD.............DEVEEEEEDCVNSNRDKVAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------lrftlpllkalandrdysgklskrtlnvvifivlhersiyrwitddefpkeise..................................
A0A4T0X4U8_9ASCO/80-192              ilyalhslgfenyaeilriyla------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....--------------------------------------KYRIFELD.............EVEKRRAKYIARKNKLQKEKLNNSTSNTNTTTT..TTTTTTTTTNTITNNNDNNDLSNSQ------------------...................------------------------.............--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------yweldsplsprssstqaspqnseil...............................................................
F0Z7Z9_DICPU/4-179                   ..........kgagslneqsva------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----------------------------------------------.............---------------------------------..-------------------------------------------...................------------------------.............--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...----LITSEKEKINQIRSFEDSHHYINFSRSQNpCLSLVDTRLSTLVLEYNPSTIQHIAGFFDLCSLMVSKTDISGFNLQIASIMSSFLPTNIKNLSFERETALKEKLAMTFSNSTVLNETFRIQNVKSVKRYLTISVTNKTFNACRIFAFSDVKKGFSISNLNYLF---------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------y.......................................................................................
A0A1I7SX44_BURXY/5-220               .....rwaplisagillflsaa------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....--------------------VL-ADSNDLEEEFTADATPLPFKAIS.............ESESESISEEESTVVVQSTTVQPTTTTKATTTT..TTTKRTTTTIKTTTGGSSSSEESSTQPSNEEREKGFIKTTEAPgvcadkhdlckfwssigecE-------SNKDWMSTNCKISCDKcngsticidrhrlCSFWASMNECESNKVWMLVHCSKACKSCKGDVIN----------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------trngefekedctfia.........................................................................
A0A8J4Q3F4_9MYCE/273-369             .............yfcileslv------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----------------------------------------PSINIK.............--------KDLVED-NHSHNIQNNNNNNSTTTT..TTTTTTT-TKTVIRNRVPTNNNNIVNNNNNNKGTN--------...................------------------------.............--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------hhpyyrdlhlisnnhssvilehfe................................................................
F1A0F2_DICPU/1-877                   ......................KELIPWDRSIDIYYKLLSTYAPVEKQQ-KSDVNIMSCYFSSDIVVLREIVKKILSSIR-----PDCFKVTNVFPKTNQ-F--LNFKNNKSFDLDSAFRYRLDAMGKNIIDDCDQAILVIDHLSRIYDSHIFSKNSLPTFKSLETLVTKYGYKISHRRFIATEWYAFLQQFKKECGGSKDFrldgEEVSKNNSPDLIGLFSFIHGVHT-NQSEEEIKISNIFSIFPFLDLEqdnvlpiytrsrpNTKSIETPSSLNKETTEITTSTPSYIRIKDIMQ..ITTTNATATPIPTQKATKVQDKNIESIPITTPQLDKKRKAIEP...................---TPRISTRKTNSLQHVRVNSLS.............LK--TNNDAIEIDDEKTDIIISDKIKNIFTSIDKS--VSNASDVKSLFNMLQKKIYDSQSLYSLLLKNKSRDSVILTNETLELAEAIDYDEIHLELLTDEVYNMASVFLISKNKNIIVPTIVDTDKLGFLWIPIVDGKVSTSLYIVPNETILDTSKVKAITKFIQMIISLADIVSFLKNQRIELPLFKSVCSDLsMELDTIILRIEDLENQIEQQIHKYhsFRSRMANTESlneQSVALITSEKEKINQIRSFVDSHHYINFSRSQDpCLSLVDTRLSTLVLEYNPSTIQHIAGFFDLCSLMVSKTDISGFNLQIASIMSSFLPTNIKNLSFERETALKEKLAMTFSNSTVLNETFRIQNVKSVKRYLTISVTNKTFNACRIFAFSDVKKGFSISNLRNIFKENTKSYSRYIEYFNGTHEIFAFFAAPCIFKITNIQYSAPEIVSDRLLSRKIKSFTFRNLSPILVDIKVGQEIITSVKPDTTQNVQIESNEFEFTVSCMKFSFGTTIISKNRLNLLTDKET-EINNRKNiLLDKINKCEELKKKFIKELD------------------------------------------k.......................................................................................
A0A8H8NDZ1_9AGAM/75-266              ..............spwqrvvm------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....---------------------HVDE-ESDEEAVVIIYGLMPAKSYE.............IELSVVAGESIKGNLTTEDENDEHNQPTSAVTQltTTQTQTVTPEATPPSSPASSSRPPTPPPRQITVEERANQLRHT...................QLALNQEHDQLTVQLKTARRDAQRadaalr.seiealKKATEKNAAGEQRAKQKILALQESVKRALAESVEMDGKVK----------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------emeral..................................................................................
#=GC seq_cons                        ................h...hs...................................................................................................................................................................................................................................t.p................p....pp.ttp..pppp.p.pptpppssTT..TTTTsTTTT.tssppps..stps.pt..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................th.h....p.h.............................................................................
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