#=GF ID   Disaggr_assoc
#=GF AC   PF08480.14
#=GF DE   Disaggregatase related
#=GF AU   Wuster A;0000-0003-4162-5931
#=GF SE   Pfam-B_4000 (release 18.0)
#=GF GA   22.60 22.60;
#=GF TC   22.60 22.60;
#=GF NC   22.50 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Repeat
#=GF CL   CL0268
#=GF RN   [1]
#=GF RM   2082820
#=GF RT   Isolation and characterization of disaggregatase from
#=GF RT   Methanosarcina mazei LYC. 
#=GF RA   Xun LY, Mah RA, Boone DR; 
#=GF RL   Appl Environ Microbiol 1990;56:3693-3698.
#=GF DR   INTERPRO; IPR013687;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   This domain is found in disaggregatases and several hypothetical
#=GF CC   proteins of the archaeal genus Methanosarcina. Disaggregatases
#=GF CC   cause aggregates to separate into single cells [1] and contain
#=GF CC   parallel beta-helix repeats.  Also see Pfam:PF06848.
#=GF SQ   45
#=GS A0A4E0PXV3_9EURY/288-486    AC A0A4E0PXV3.1
#=GS L0KWP9_METHD/313-488        AC L0KWP9.1
#=GS A0A4R0RGH8_9APHY/150-257    AC A0A4R0RGH8.1
#=GS L0L1P8_METHD/343-527        AC L0L1P8.1
#=GS L0KY94_METHD/272-464        AC L0KY94.1
#=GS Q8PXT0_METMA/261-458        AC Q8PXT0.1
#=GS L0L0E2_METHD/324-517        AC L0L0E2.1
#=GS Q8PXS1_METMA/270-470        AC Q8PXS1.1
#=GS A0A6P1M9Y8_9BACT/907-1091   AC A0A6P1M9Y8.1
#=GS A0A1M4Z0H3_9BACT/299-426    AC A0A1M4Z0H3.1
#=GS R5YPF6_9FIRM/642-734        AC R5YPF6.1
#=GS B8FK54_DESAL/2634-2796      AC B8FK54.1
#=GS Q8PXU6_METMA/268-452        AC Q8PXU6.1
#=GS R5VI53_9CLOT/580-726        AC R5VI53.1
#=GS Q8THR8_METAC/274-457        AC Q8THR8.1
#=GS L0KV87_METHD/312-495        AC L0KV87.1
#=GS A0A373LEA3_9FIRM/583-724    AC A0A373LEA3.1
#=GS A0A7Y5NUG0_9DELT/417-481    AC A0A7Y5NUG0.1
#=GS L0KZL0_METHD/276-479        AC L0KZL0.1
#=GS E2M4K2_MONPE/25-133         AC E2M4K2.1
#=GS Q8TKN2_METAC/356-546        AC Q8TKN2.1
#=GS Q8PUS9_METMA/278-465        AC Q8PUS9.1
#=GS Q8TRX2_METAC/258-418        AC Q8TRX2.1
#=GS L0KYP6_METHD/321-525        AC L0KYP6.1
#=GS Q8TNA9_METAC/274-466        AC Q8TNA9.1
#=GS Q8TRX3_METAC/275-470        AC Q8TRX3.1
#=GS A0A1Q2MDE7_9BACT/746-850    AC A0A1Q2MDE7.1
#=GS Q8PTB3_METMA/280-477        AC Q8PTB3.1
#=GS Q8TNF1_METAC/197-388        AC Q8TNF1.1
#=GS L0KXE4_METHD/313-488        AC L0KXE4.1
#=GS A0A7I8MXU1_9DELT/312-440    AC A0A7I8MXU1.1
#=GS A0A1G6WKR0_9GAMM/398-488    AC A0A1G6WKR0.1
#=GS Q8PXU7_METMA/268-468        AC Q8PXU7.1
#=GS Q8PSX7_METMA/258-449        AC Q8PSX7.1
#=GS A0A848MDR7_PAELE/410-523    AC A0A848MDR7.1
#=GS A0A4E0PVN5_9EURY/336-521    AC A0A4E0PVN5.1
#=GS A0A4E0PU39_9EURY/271-470    AC A0A4E0PU39.1
#=GS Q8TRW0_METAC/268-463        AC Q8TRW0.1
#=GS Q8TLE9_METAC/305-510        AC Q8TLE9.1
#=GS A0A1U9NGD7_9BACT/942-1020   AC A0A1U9NGD7.1
#=GS A0A2H5WMJ4_9BACT/1071-1243  AC A0A2H5WMJ4.1
#=GS Q8PSY5_METMA/251-443        AC Q8PSY5.1
#=GS A0A4S3L255_9GAMM/427-487    AC A0A4S3L255.1
#=GS A0A1U9NPY4_9BACT/215-399    AC A0A1U9NPY4.1
#=GS Q8PXS2_METMA/253-454        AC Q8PXS2.1
A0A4E0PXV3_9EURY/288-486               ...............................................................................yntt-----IAYNTIYDTREMGI.VLaIGAg..aND...LP...A..TSARDV...HIHHNTIHG...A...G...TN..YrvG..........Y..P..Y.....G.....G.G...I.W..LD.G.....WT......D..TI.IENN.VI..DGSMG..DG..IA.YGQRFA.................-NTQS..ATYK.TIVRNN......IIT.NTV......dSPV.L.TNDGYGINNR....LGSN.....YRFVL.......ENNVV......WN.NV.....NGN..YNN..I.....D...sY..DT...DINADPL.FA.....DPS...D.....RDYHLKSAA.....GRW..SD..G..DWILDPV.TSPAIDAG....................................................
L0KWP9_METHD/313-488                   ..................................................................................f-NNIEIYKNKIHNIRGSGI.WM.FAA....YS...DN...V..IRAKNV...HIHHNTFTK...V...G...QH..A..S..........N..TgyT.....N.....A.A...I.T..MQ.N.....FD......N..TI.IENN.VF..DDGGN..AA..IK.WYAWSS.................VPQQK..AKFT.THVRNN......VIK.NND......gMSG.V.SGSGVGIWNT....QPSY.....ATFIV.......QKNDF......SN.NK.....NGD..TSG..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------ggftmsnnanvapsssgstvvnkanta.........................
A0A4R0RGH8_9APHY/150-257               ...............................................................................efvh-------------------.--.---....--...--...-..-SCNNV...TVQSNDIGP...C...G...SD..Q..F..........Q..Q..W.....AdgisdG.G...I.V..LF.G.....AP......G..TL.VENN.TI..FVETQ..TL..LG.GINMVD.................YDPWG..GNYTdTIVREN......IIL.GGFs.....tDTP.Q.AGEQKGANND....----.....-----.......-----......--.--.....---..---..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------dvii................................................
L0L1P8_METHD/343-527                   ..................................................................................f-NNIEIYNNKISTMRGSGI.LM.VAA....YT...DN...V..IRAKNV...YIHNNTFTK...V...G...QDplN..T..........G..Y..T.....N.....A.A...I.T..MQ.N.....FD......N..TI.IENN.VF..DDGGN..AA..IK.WHVWSGypnh........dafvsVAQQK..AQFT.TYVRNN......VIM.NND......gMSG.V.TGSGVGIWNT....QPSY.....AKFIV.......QSNNF......YN.NK.....NGD..TYG..G.....Gf..tM..SN...NVNTAPS.TS.....D--...-.....---------.....---..--..-..-------.--------sttttpspag..........................................
L0KY94_METHD/272-464                   ..................................................................................s-ENIEIYRNRIHTLNGAAI.WI.FGE....DT...DN...V..VRGKDV...YIHHNIIYD...V...G...QY..DkfT..........G..Y..S.....N.....A.A...I.V..IG.Q.....FN......N..TV.IENN.VI..HNGGH..AG..IK.YYQYPN.................TASMN..ESFT.TIVRNN......VIL.GSN.......KNN.-.---DRGLWNT....DEIN.....HTFIS.......NNNCI......YNvDL.....NYD..GDG..I.....I....H..KD...DIYVDPL.FA.....DMA...K.....RDYHLRSAA.....GRW..SG..N..SWISDSV.TSPLIDAG....................................................
Q8PXT0_METMA/261-458                   ...................................................................................MNNIKIYDNVITNTYGPGI.WL.IGT...aGA...YD...K..SLS-SV...HICHNIFYD...S...G...TN..P..S..........I..E..W.....V.....G.G...V.L..GS.G.....FH......N..VL.VENN.VF..DGVHN..AA..VV.NMYSTDt...............nAGPSG..TGFT.TTVRNN......IIV.NTVp.....rTKN.S.AGTGYGVINH....LPSS.....HTIVL.......ENNCL......YN.NA.....AGN..YKN..V.....K....S..TT...DIYADPL.FA.....GQS...L.....HDYHLKSVA.....GHW..SG..T..KWVKDSV.SSPCIDAG....................................................
L0L0E2_METHD/324-517                   ..................................................................................s-ENIEIYNNLFHTLYGSAI.WI.AGE....DA...DN...V..VRGKDV...YIHHNIIYN...V...GqypID..T..G..........Y..-..S.....N.....A.A...I.T..IG.Q.....FN......N..TR.IENN.VI..DNGGH..AG..IK.YYQYVN.................SYRMA..SKFT.TTVKNN......III.NCA.......KNV.-.---ATGVWNY....NSEN.....HKFIL.......NNNCI......YW.NT.....KGA..YVG..A.....Ni..iR..SG...DIYVDPL.FV.....SSA...T.....RDYHLKSTA.....GHY..SS..G..KWIADTV.SSLLIDAG....................................................
Q8PXS1_METMA/270-470                   ...................................................................................MDDIEVYNNVIHNTFGPGL.WL.IGY...dSS...YS...K..EEARNV...HIHHNIFYS...T...G...TN..P..S..........I..D..W.....V.....G.G...I.V..IS.G.....FY......D..TL.IENN.VF..DGVYH..AA..VV.HMYPDGks.............adLSPKG..KGYT.TIVRNN......IIA.NTLe.....rKKS.S.LGTGYGVINY....LPES.....HSFVI.......QNNCL......YN.NK.....GGD..FIN..A.....T....S..TG...SVYENPL.FA.....SRR...N.....HDYHLKSTG.....GRW..NG..K..TWVKDRV.ISPCIDAG....................................................
A0A6P1M9Y8_9BACT/907-1091              ......................................................................tvaggtlsncwvr-------------------.--.---....NN...FS...Y..YLAGGV...YLYDGLVKD...C...R...IE..N..Nl........cY..Y..Y.....G.....G.G...L.L..TR.G.....G-......-..-L.VENS.II..DGNQS..-G..--.------.................LDAGG.vEVWG.GTIRNC......TFV.NN-.......YAG.G.YGGGVDIGDV....ALVE.....NCIVL.......SNNAAlggdnwYE.WV.....PMNmrYSC..T.....T...pL..PSgigNMDIDPL.FA.....DFD...A.....GDYHLRSTY.....GRF..AA..G..GWVVDSE.DSPCIDFG....................................................
A0A1M4Z0H3_9BACT/299-426               .................................................................................ar--NIRIHNNLVYNMKGAGI.LF.GLW....GE...-N...R..LRS-DI...HIYNNTLYK...C...G...SE..G..W..........F..S..G.....N.....V.GsidI.L..ST.N.....CR......D..VY.IYNN.IC..DKGFD..YE..IG.FGFKKN.................ELPEA.lEKQN.IIVKNN......LVS.GTK.......N--.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------kevrigqfdakvieyip...................................
R5YPF6_9FIRM/642-734                   .........................................................................tklpiiknci-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.I.AGNKRGFKNL....NDDT.....DTSNI.......TYTCI......YN.DS.....WNG..NTY..N.....Y....G..IG...CIFEEPL.FA.....NIE...K.....GNYHLKSKG.....GRW..NG..T..MWIADDV.TSPCINAG....................................................
B8FK54_DESAL/2634-2796                 .............................................................................flqgss-------------------.--.---....--...--...-..---ENV...LIEGNVFGV...T...H...EA..R..T..........P..L..L.....R.....-.-...I.G..AS.G.....SG......-..NR.IVNN.IM..TSAYN..AG..TGvYVDGSI.................TELEI..VNNT.MVDLIN......GID.CI-.......DSA.S.PLIAFNIIAFnsegIYAD.....NTFDV.......HYNCV......YG.NG.....ADY..DST..I.....T....H..AT...DINEDPL.FV.....DAA...G.....KDFHLQEIS.....---..--..-..-------.--------pcvdalessaaatag.....................................
Q8PXU6_METMA/268-452                   ...................................................................................MDDIEIYNNLLYETNAAGI.WI.TGY...gPA...YS...K..DSAKDV...YIHNNRFYK...T...G...IN..P..G..........A..A..W.....A.....G.G...V.V..LN.G.....FY......N..TL.IEDN.VF..DGCYG..AA..IA.HKQVDE................eFSSPG..SDYT.TTARNN......III.NTR.......SSP.T.AGEGYAFYNQ....LEDS.....HSFIL.......QNNCL......LN.NA.....GGN..YMH..A.....E....S..TS...DREATPE.LI.....EQL...N.....KD-------.....---..-D..P..SEIQDLP.CAEAIKS-g...................................................
R5VI53_9CLOT/580-726                   cqisgftngtgisahltsdgsnensakditsqltlnhltvtgcangirysgsvlpsiknsifanndttlslsgssaenrkgtd-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....----I.......TYSCV......YN.KK.....AND..SLS..D.....Y....G..TG...CISKDPC.FA.....DSS...A.....GDFHLKSTA.....GRW..NG..S..SWVKDKV.TSPCIDAG....................................................
Q8THR8_METAC/274-457                   ...................................................................................MNDIEIYNNLIYETNTAGI.WI.TGY...gSE...YS...K..DSAKDV...YIHNNKFYK...T...G...IN..A..G..........A..D..W.....S.....G.G...I.V..LN.G.....FY......D..TL.IENN.IF..DSCYG..AA..IA.HKEVDE................eFSAPG..SNYT.TIARNN......III.NTQ.......SSP.T.AGEGYAFYNK....LQNT.....HSFIL.......ENNCL......SN.NL.....GGD..YMY..A.....S....S..TS...DVQADPA.LI.....EQI...G.....KN-------.....---..--..G..SSVQNLP.CADAINAG....................................................
L0KV87_METHD/312-495                   ..................................................................................f-NNIDIYNNKIHSIRGSGI.WM.FAA....YT...DN...V..IRAKNV...HIHHNTFTK...V...G...QH..A..L..........N..TgyT.....N.....A.A...I.T..MQ.N.....FD......N..TI.IENN.VF..DDGGN..AA..IK.-WYAWS.................PIPQQ.kAQFT.TYVRNN......IIK.NND.......GMS.GvPGSGVGIWNT....QPSY.....AKFIL.......QNNEF......YN.NK.....NGA..TN-..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------apvanggadktvtvespvtfdasastddigivsysw................
A0A373LEA3_9FIRM/583-724               ........................................................nckihnfnykdyegvalqaevseetad-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.-----Kvv............fenITMAD..NNYG.IIAKKNrltklpIIK.NC-.......IIA.G.NKKGFDFNNE....I-DT.....SS--I.......TYSCI......YN.DS.....WNG..NTY..G.....Y....G..EG...CIFTDPL.FA.....DSK...N.....GDFHLMSKA.....GRW..YN..S..QWVVDDV.SSPCIDAG....................................................
A0A7Y5NUG0_9DELT/417-481               ...................................................................aasysvwtgigkgvra-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....G..AG...QLAKDPL.FA.....DPK...S.....LDFHLRSSA.....GRW..NP..SagAWTNDAAgSSPAIDA-a...................................................
L0KZL0_METHD/276-479                   ..................................................................................f-ENIEIYNNKIYNVLGAAI.WM.SAS....YP...DD...I..IHAKNV...HIYHNTFSK...V...G...QY..G..S..........N..TgyS.....N.....A.A...I.V..LC.S.....FD......N..TI.IENN.VF..DDGGH..AG..IK.WFTRSG.................RPIQD..VTYT.TTIRNN......IIM.NSD......gVSS.V.TGSGVGIWNT....DSTH.....CKFVV.......QNNDI......YN.NK.....NGQ..TYG..S.....Sf..tL..TN...NLNVNPQ.CI.....DST...NsnvasRDYHLKSKA.....GHY..SS..G..TWIADSV.SSTLIDTG....................................................
E2M4K2_MONPE/25-133                    ..........................................................................hitqgpltc-------------------.--.---....--...--...-..---NNA...TVQHNEIGP...C...G...TD..Q..R..........S..N..W.....A.....D.G...I.S..LS.C.....A-......N..SV.VRNN.TI..KGATD..GN..YT.QLGGINl..............vdYSPYH..GDYTgTVVRNN......TIL.GAY.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------ahgeqrssdktrgenldhvfi...............................
Q8TKN2_METAC/356-546                   ...................................................................................MNDIEVYNNTIYDTYGPGI.WL.IAF...gEP...YS...K..TEAQNV...HIHHNIFYG...C...G...TH..R..T..........Y..D..W.....L.....G.G...I.V..TS.G.....FY......D..TL.IENN.VF..DANYN..AA..VV.YTYPTGsry...........dtdFTPKGidGNYT.TIVRNN......IIT.NTLk.....rKYS.P.EGTGYGVIDN....FPET.....HSFVL.......ENNCL......YN.NS.....AGN..YPN..C.....T....S..TT...DIYADPL.FV.....NQN...E.....HDYCLKPN-.....---..--..-..-------.--------spcigagy............................................
Q8PUS9_METMA/278-465                   ...................................................................................MNDIEIYNNSIHNTFGPGL.WL.IGY...dSS...YP...K..KEAQNI...HIHRNTFYS...T...G...TN..P..S..........I..N..W.....V.....G.G...I.V..TS.G.....FY......D..TL.IENN.IF..DGVYH..AA..VI.HMYPDGkv.............tdLSPAG..TGHT.TTVRNN......IIV.NTQk.....rTEN.P.DGTGYAVINY....LPET.....HSFVL.......ENNCL......YN.NS.....AGN..YKN..A.....S....S..TT...DFYADPL.FV.....DQK...K.....HNYHLKSNS.....---..--..-..-------.--------pcikagns............................................
Q8TRX2_METAC/258-418                   ...................................................................................MENIEIYNNNLHDLRCWGI.WL.YGY...yKNgagYD...S..DQINNI...HIHDNSILR...C...G...RS..E..Ns.......yqY..R..E.....A.....G.G...I.I..IQ.G.....F-......N..AL.IEDN.II..DDNAK..FG..VA.FEYWSYskl..........gesyKPPAG..EKFT.VILKNN......NIR.NTVk.....sEYP.K.DKQGYGVANI....LDSN.....HVFVL.......KGNTV......SG.SE.....TKN..Y--..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------lc..................................................
L0KYP6_METHD/321-525                   ..................................................................................f-DDIEIYNNKIYSINGAGI.WM.FAG....YP...DN...V..IRAKNV...NIHHNTFSK...V...G...QY..T..A..........N..TgyS.....N.....A.A...I.V..IQ.N.....FD......N..TI.IENN.VF..DDGGH..AA..IKwYVWSGH.................ITQQK..AEFT.TYVRNN......IIM.NND......gVSG.V.TGSGVGIWNT....QPSY.....AKFIV.......QNNNI......YN.NE.....NGQ..TYG..S.....Gf..tM..SN...NLNVDPH.CV.....DQT...NsklssRDYHLKSKV.....GRY..SS..G..KWVTDSI.SSPLIDAG....................................................
Q8TNA9_METAC/274-466                   ...................................................................................MDDIEVYNNVIYKTALAGI.WI.FGS....GS...YS...A..STA-NV...HVHHNQIYD...T...G...TK..T..S..........N..S..I.....I.....G.G...I.V..SN.G.....F-......S..GL.IENN.VI..DGAYG..AG..IV.QKTVYS.................PAPSG..SGFL.LTVRNN......ILS.NSR.......SSS.G.GGSGYGINNE....LSGT.....HSFVL.......QNNCY......YG.SA.....GGD..SRN..V.....Q...lS..AS...DIKVDPQ.FA.....DRS...S.....HDYHLKSIA.....GRW..NG..K..SWITDSA.SSPCIDAG....................................................
Q8TRX3_METAC/275-470                   ...................................................................................MDDIEIYNNRIYHTRAWGI.WI.VGY....SK...YD...K..DRAKGV...WIHHNIIYD...T...G...TS..S..T..........L..H..E.....A.....G.G...I.V..VQ.G.....FN......N..TI.IENN.VI..DGNRK..YG..VAyELYPAY.................GIPKD..NGFV.TIVRNN......IIS.NTI......rNVA.D.VGSGWGVKNC....DPSN.....HTFIL.......ENNCV......YN.SA.....AGN..YVN..V.....T....P..TT...DINVDPL.YA.....DIS...N.....HDYHLKSKA.....GRW..SN..T..GWITDNV.SSPCIDAG....................................................
A0A1Q2MDE7_9BACT/746-850               ...............................................................................gssp-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......VIE.NCT.......IVS.N.QGLGISSADS....NPLI.....DSCII.......WDNDQ......GS.FS.....GGSpvYSC..IegnplS....S..NG...NISLDPC.FA.....DPE...N.....GNYQLKSQA.....GRWlpEQ..K..KWFNDPV.ASPCIDGG....................................................
Q8PTB3_METMA/280-477                   .................................................................................sm--DVEIYDNLITNTYGPGI.WV.IGT...aGA...YD...K..SLT-SC...HIHHNIFSG...S...G...TN..K..N..........I..Q..W.....V.....G.G...V.L..GS.G.....FH......N..VL.VENN.VF..DGVHN..AA..VV.NMYKTDd...............nAGPSG..KGYT.TTVRNN......IIV.NTVp.....rKTK.G.TNTGYGVVNC....LPKS.....HNMVL.......EYNCV......YN.NA.....AGN..YKN..V.....N....H..PT...DINADPL.FA.....DSK...N.....GDYHLKSTA.....GRW..TG..S..AWVKDSV.SSPCIDAG....................................................
Q8TNF1_METAC/197-388                   ...................................................................................MDDIEVCNNVIYNTALSGI.LV.FGS....GN...YS...T..ASA-NV...HIHHNQIYN...T...G...IS..L..S..........S..E..V.....T.....G.G...V.L..AE.G.....F-......N..GL.IENN.VI..DGAYG..AG..IV.QDRAYY.................SAPDG..SGYV.ITVRNN......IIT.NT-.......YMS.P.AGEGYGICNL....LTDT.....HSFVL.......QNNSF......YN.NA.....GGD..YTG..V.....E...aS..PS...NINSDPQ.YA.....DRD...K.....HDYHLKSKA.....GRW..NG..S..SWVNDNI.SSPCIDAG....................................................
L0KXE4_METHD/313-488                   ..................................................................................f-NNIDIYNNKIHSIRGSGI.WM.FAA....YT...DN...V..IRAKNV...HIHHNTFTK...V...G...QH..A..L..........N..TgyT.....N.....A.A...I.T..MQ.N.....FD......N..TI.IENN.VF..DDGGN..AA..IK.WYAWSS.................VPQQK..AQFT.TYVRNN......VIK.NND......gMSG.V.TGSGVGIWNT....QPSY.....AKFTV.......QSNNF......YN.NK.....NGD..TYGggF.....T....M..SS...NVNTAPS.--.....---...-.....---------.....---..--..-..-------.--------tsgstvvnkvdaa.......................................
A0A7I8MXU1_9DELT/312-440               .......................................................angiynsqpfwqegkviinqtcrnylyk-------------------.--.---....--...--...-..----GN...YIHHIGVRR...I...N...QN..K..D..........A..-..-.....-.....H.A...I.G..IQ.G.....GY......D..GL.IEGN.VI..DNCG-..SG..IVlYAYTEQ.................-ELKD..----.TIVRKN......IVR.NLH.......-KR.G.GATGYGIATM....CNN-.....DSF--.......-----......--.--.....---..---..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------sdktgnrfyqnliin.....................................
A0A1G6WKR0_9GAMM/398-488               ........................................ggaailveasstltlknsilwgntrefvsysggsyaisysita-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....Q...aG..TG...NRALDPG.FV.....SPA...T.....GDYHLQSAG.....GHF..SS..G..GWVVDAR.SSPAIDAG....................................................
Q8PXU7_METMA/268-468                   ...................................................................................MDDIEVYNNTIYNTYGPGI.WL.VGY...dNS...YS...T..EEAQNV...QIHHNIFYS...T...G...TN..P..N..........I..D..W.....V.....G.G...I.V..TS.G.....FY......N..TL.IENN.VF..DGTYH..TA..IA.LMHPTGys.............tdLSPKD..TGYT.TIVRNN......IIV.DTLe.....rKND.P.EGTGYGVINY....LPET.....HSFIL.......ENNCF......YN.NT.....AGN..YKN..A.....N....S..TG...DIYENPR.FA.....NQK...E.....NDYHLRSIG.....GRW..NG..K..TWVKDFQ.TSPCIDAG....................................................
Q8PSX7_METMA/258-449                   ...................................................................................MDDIEIYNNVIYKTARVGM.WI.FGA....GS...YP...D..SSA-DL...HIHHNQIYD...T...G...TK..S..S..........S..I..I.....I.....G.G...I.I..SD.G.....F-......N..AL.IENN.VI..DGVYG..AG..IV.QKNVYS.................SAPSG..SGYV.LTLRNN......IIT.NS-.......RSS.S.GGSGCGVSNE....LTGT.....HSFVL.......QNNCF......YG.NE.....AGN..CKN..V.....Q...vS..SS...DIKADPR.YA.....DRN...N.....HDYHLKSNT.....GRW..NG..K..SWVNDGI.NSPCIDAG....................................................
A0A848MDR7_PAELE/410-523               ..................................................................................g-NHIEIQGNSVKDTYMAGI.YI.AVE....GS...YN...T..ANVNHV...HIDSNLIDH...T...G...TA..K..P..........Q..N..H.....P.....N.A...L.V..YA.S.....Q-......-..GV.IDNV.TF..SNN--..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....-..--...-------.--.....---...-.....---------.....---..--..-..-------.--------tfqnaahrglgvwgdgdirnifytkntlinsiganttfskg...........
A0A4E0PVN5_9EURY/336-521               ................................................................................dsy--NITIAYNAIYDTREMGI.VL.ATAr.gaNN...MP...V..TSARDV...HIHNNIIYG...S...G...TNyrT..G..........H..P..Y.....G.....G.G...I.W..LD.G.....WN......N..TT.VENN.II..DGSMG..DG..IA.YAQRFS.................GHNDT..AIYT.TFVRNN......IIM.NTV.......NSPiQ.TGDGYGISNR....LGSN.....YNFVL.......ENNVV......WN.NE.....NGN..YNN..I.....S...sH..DT...DININPL.FA.....DPW...N.....Y--------.....---..--..-..-------.--------inykvslwrwhlt.......................................
A0A4E0PU39_9EURY/271-470               ...................................................................................MYNITIAYNTIYDTREMGI.VLaIGKd..aND...LP...A..TSARDV...HIHHNTING...A...G...TN..YrvG..........Y..P..Y.....G.....G.G...I.W..LD.G.....WT......D..TI.IENN.VI..DGSMG..DG..IA.YGQRFA.................-NTQS..ATYT.TIVRNN......IVT.NTV......dSPV.L.TNDGYGINNR....LGSN.....YRFVL.......ENNLV......WN.NV.....NGN..YNN..V.....G...sH..DT...DINADPL.FA.....DLS...N.....RDYHLKSAA.....GRW..SD..G..DWILDPV.TSPAIDAG....................................................
Q8TRW0_METAC/268-463                   ...................................................................................MDDIEIYNNLIYHTHAWAI.WL.VGY....GK...YD...K..DKAKGV...WIHHNVIYD...T...G...TS..S..T..........L..H..E.....A.....G.G...I.V..VQ.G.....FN......N..TI.IENN.VI..DGNRK..YG..VAyELYPAY.................GIPKD..NGFV.TIVRNN......IIS.NTI......rNVA.D.VGSGWGVKDC....DPSN.....HTFIL.......EYNCV......YN.SA.....AGN..YVN..V.....A....P..TT...DINVDPL.YA.....DIS...N.....RDYHLKSKA.....GRW..SN..A..GWTTDNV.SSPCIDAG....................................................
Q8TLE9_METAC/305-510                   ...................................................................................MNDIEVYNNIIYDTYGPGI.WL.IAY...gKS...YA...K..TEAANV...HIHHNIFYG...C...G...TN..Q..N..........Y..N..W.....V.....C.G...I.E..TS.G.....FY......D..TL.IENN.VF..DGNYN..AA..IM.YMYPSApq............fsgLEPNGmsDDYT.TIVRNN......IIV.NTLk.....rKYS.S.EGTGKGVVNY....YPET.....HKFIL.......QNNCI......YN.NA.....GGA..YKN..A.....D....S..DS...DIYVDPL.FV.....DQK...N.....HDYHLKSTSpaagmGVY..AG..A..STVTDIK.--------ntvne...............................................
A0A1U9NGD7_9BACT/942-1020              ....................................................lienciswgnsiadiygggevrysciergsp-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....G..ET...NITDEPA.FV.....DLA...G.....QDYHLRSER.....GRY..DPavE..KWVLDDV.TSPCIDAG....................................................
A0A2H5WMJ4_9BACT/1071-1243             ..........................................................................ivisnnlii-------------------.--.---....--...--...-..------...-------YN...R...S...LD..V..S..........G..S..-.....G.....A.G...I.L..VQ.G.....ANpf..gaD..VQ.ILNN.LIarNAAYN..SA..AV.YLRYASaqlinnt..iayntsvsASLGG..GVYC.SDSTNT......LFA.NN-.......IVA.F.QENGPGIDRK....NVST.....ATVTL.......RNNCV......YN.PS.....SAN..YRN..I.....A...aSayAS...DINLDPR.FV.....DGS...N.....NNFHLGD--.....---..--..-..-------.--------spcidrgsasdaa.......................................
Q8PSY5_METMA/251-443                   ...................................................................................MDNIEIYANTIYNTALPGI.LV.FGS....GS...YS...N..SSA-YV...HIHHNQIYD...T...G...TD..S..N..........N..K..L.....I.....G.G...I.V..SE.G.....F-......N..GL.IENN.VI..DGAYG..NG..IA.QDKTYY.................HSPDG..SGYV.LTVRNN......IIS.NIR.......SSA.S.GIAGYGIRNQ....LPET.....HFFVL.......QNNSL......YN.NL.....GGD..YAG..V.....E...aS..PW...DIVADPQ.YA.....DRD...K.....HDYHLKSKA.....GRW..NG..S..SWVIDNI.SSPCIDAG....................................................
A0A4S3L255_9GAMM/427-487               ....................................................................sggtvtvsysittqa-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..-.....-.....-.-...-.-..--.-.....--......-..--.----.--..-----..--..--.------.................-----..----.------......---.---.......---.-.----------....----.....-----.......-----......--.--.....---..---..-.....-....G..TG...NFSADPL.FA.....NAA...A.....GDYHLRSAG.....GRY..TP..S..GWVVDAV.TSPAIDAG....................................................
A0A1U9NPY4_9BACT/215-399               ......................................inncsvnqnalyglsdcngqirnceitqnrdqglnycrtaevvnc-------------------.--.---....--...--...-..------...---------...-...-...--..-..-..........-..-..L.....V.....T.G...N.E..GN.G.....FY......EfsGQ.IKNC.TI..VGNQY..HG..IS.MTTSND.................YGP--..----.ATIANC......IIT.NN-.......---.-.--GSYGISNR....YPER.....CPTTL.......KFNNI......WA.NG.....LGN..YNG..L.....K...pG..AT...DTHHDPL.FAvagywDENswlE.....GDYHLQSEA.....GRW..TE..N..GWVNDSV.TSSCVDAG....................................................
Q8PXS2_METMA/253-454                   .................................................................................vm--NVEIYDNLITNTYGPGI.WV.IGT...eGA...YD...K..TLT-SC...YIHHNIFNG...T...G...TN..K..N..........I..Q..W.....V.....G.G...V.L..GS.G.....FH......N..VL.IENN.VF..EGVHN..AA..VV.NMYMTYd...............nAGPSG..SGFT.TTIRNN......IIA.NTTprl.twnVRE.G.QGTGYGILNC....LPKS.....HNMVV.......EYNCV......YN.SA.....AGD..YKN..V.....N....H..PT...DINVDPL.FV.....DSK...N.....GDYHLKSQT.....GRW..TG..S..AWVKDSV.SSPCIDAG....................................................
#=GC seq_cons                          .....................................................................................sIclhtNhlhph.h.uI.hh.hu......s....s...h...pu.sV...aIHcNhhht...s...G...pp..t..s................h.....s.....u.u...I.h..hp.u.....a.......s..sl.IENN.lh..Dssht..su..lh..h...t.................hssts..stas.ohlRNN......IIh.Ns..........s.s.tssGhGlhNh.....spp.....ppFll.......psNsh......YN.st.....sGs..h.s..h.....t....t..ss...sl.hDPh.as.....-.t...p.....tDYHL+Sts.....G+a..ts..t..tWl.D...sSshIcuG....................................................
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