#=GF ID   DnaG_cat_HB
#=GF AC   PF21650.1
#=GF DE   DNA primase DnaG, catalytic core, helical bundle
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF20409
#=GF GA   27.00 27.00;
#=GF TC   28.00 34.50;
#=GF NC   26.90 25.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF RC   Paper describing PDB structure 4e2k
#=GF RN   [1]
#=GF RM   22795082
#=GF RT   Binding mechanism of metalNTP substrates and stringent-response
#=GF RT   alarmones to bacterial DnaG-type primases.
#=GF RA   Rymer RU, Solorio FA, Tehranchi AK, Chu C, Corn JE, Keck JL,
#=GF RA   Wang JD, Berger JM;
#=GF RL   Structure. 2012;20:1478-1489.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in DNA primase from Staphylococcus aureus
#=GF CC   (DnaG) and similar proteins predominantly found in firmicutes.
#=GF CC   DnaG is an RNA polymerase that catalyses the synthesis of short
#=GF CC   RNA molecules used as primers for DNA polymerase during DNA
#=GF CC   replication. This entry represents the helical bundle (HB) found
#=GF CC   at the C-terminal of the catalytic core of DnaG [1].
#=GF SQ   13
#=GS Q2FY11_STAA8/365-427      AC Q2FY11.1
#=GS A0A0D6XP56_9STAP/364-426  AC A0A0D6XP56.1
#=GS B9E6V3_MACCJ/361-423      AC B9E6V3.1
#=GS A0A4R6BXG6_9STAP/360-422  AC A0A4R6BXG6.1
#=GS A0A178PJB5_MAMLE/363-425  AC A0A178PJB5.1
#=GS A0A4Q1B8V7_9STAP/362-424  AC A0A4Q1B8V7.1
#=GS K9B539_9STAP/364-426      AC K9B539.1
#=GS DNAG_STAEQ/365-427        AC Q5HNY6.1
#=GS Q49Y05_STAS1/367-429      AC Q49Y05.1
#=GS A0A0C2HQT4_9STAP/359-421  AC A0A0C2HQT4.1
#=GS A0A380H341_9STAP/365-427  AC A0A380H341.1
#=GS A0A143PAC5_9STAP/363-425  AC A0A143PAC5.1
#=GS A0A3N5BJS4_9STAP/365-427  AC A0A3N5BJS4.1
Q2FY11_STAA8/365-427                 ..KSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKALNDVAPFFNVSPEQLANE..
A0A0D6XP56_9STAP/364-426             ..KSFVSFKLKQHQQEIQNNDLAFEKHYKVFVDDAALIQSQILRQKVVQEAAELFKVHPDSLLNE..
B9E6V3_MACCJ/361-423                 lt--YVSFYMRHYLDEIKNNDLAYEKHLNNIIEDAKLMNSEHLQKKVLHEITELFNVDFDSLK--fk
A0A4R6BXG6_9STAP/360-422             .l-SFVSYKLKQWSGQVASNDLVFDQRLKEATSDISRIKSPALRKKVLHEASELFKVDFDNLNFE..
A0A178PJB5_MAMLE/363-425             ..QSFVGFKAQQLYYANENNDLKHEQHLEELINDINLIRSDFLRKKVLQQVADLYKVDVNSLKN-q.
A0A4Q1B8V7_9STAP/362-424             qh--YLSYYLKKYKKEIENNDLAYEKHLQKFLDDVKLMNSAHLQKKVLHEASELFKVDFDVLNF-q.
K9B539_9STAP/364-426                 .v-AFVSYKMRQYKDEIENNDLAYERYLKEITHDVGFMKSDLLRKKVLQEVAELFKVSFDSLNNE..
DNAG_STAEQ/365-427                   ..QSFVLFKVKMYQNEINHNDLAYEKHFKETVRDLSLVNSGIIRNKLIQNIADIFKVNPETIQYE..
Q49Y05_STAS1/367-429                 ..KSFIIYKIHTHQDEIENNDLAYERYLKEITNDISFMQSTILRKKILQEVSELFKVSLDSLNNE..
A0A0C2HQT4_9STAP/359-421             rh--YIHFKAEHLLEESMNNDMAFSNNLKMLTDHLRHVKDQVIRERLIQHISELYKVDRKSIE--qn
A0A380H341_9STAP/365-427             ..KSFVLFKTQLHQDEINNNDLSYERYFKEALNDISLVKSSIIRNKLIQNVADIFKISPEMIEHE..
A0A143PAC5_9STAP/363-425             ..KAFVLYKVNLHKEEIEHNDMAYEKYLKEITDDISLMQSGILQKKVLQDVSELFKVSFDSLNNE..
A0A3N5BJS4_9STAP/365-427             th--YLIQKVNDYEQEIHDNDVQFERIYNEITSEIPMIKSSVLREKVIKHVSSVFQIDVQTIT--qs
#=GC seq_cons                        ...uFVtaKlcpapcEIpNNDLAYE+aLKElscDluLhpSslLRcKVLQ-luELFKVsh-oLp.E..
//