#=GF ID   DncV_C
#=GF AC   PF21713.1
#=GF DE   Cyclic GMP-AMP synthase, C-terminal domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF17384
#=GF GA   28.40 28.40;
#=GF TC   28.70 28.40;
#=GF NC   28.10 28.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF RC   Paper describing PDB structure 4txy
#=GF RN   [1]
#=GF RM   25131990
#=GF RT   Structure-guided reprogramming of human cGAS dinucleotide
#=GF RT   linkage specificity.
#=GF RA   Kranzusch PJ, Lee ASY, Wilson SC, Solovykh MS, Vance RE, Berger
#=GF RA   JM, Doudna JA;
#=GF RL   Cell. 2014;158:1011-1021.
#=GF RC   Paper describing PDB structure 4u03
#=GF RN   [2]
#=GF RM   25201413
#=GF RT   Structural biochemistry of a Vibrio cholerae dinucleotide
#=GF RT   cyclase reveals cyclase activity regulation by folates.
#=GF RA   Zhu D, Wang L, Shang G, Liu X, Zhu J, Lu D, Wang L, Kan B, Zhang
#=GF RA   JR, Xiang Y;
#=GF RL   Mol Cell. 2014;55:931-937.
#=GF RC   Paper describing PDB structure 4xj1
#=GF RN   [3]
#=GF RM   25865248
#=GF RT   Structural Basis for the Catalytic Mechanism of DncV, Bacterial
#=GF RT   Homolog of Cyclic GMP-AMP Synthase.
#=GF RA   Kato K, Ishii R, Hirano S, Ishitani R, Nureki O;
#=GF RL   Structure. 2015;23:843-850.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found  Cyclic GMP-AMP synthase from Vibrio
#=GF CC   cholerae (DncV), a prokaryotic cGAS-like enzyme that synthesises
#=GF CC   cyclic GMP- AMP (c-GAMP) and stimulates intestinal colonization.
#=GF CC   DncV adopts a structure and topology that are typical of the
#=GF CC   nucleotidyltransferase superfamily. It is organised into two
#=GF CC   domains: an N-terminal domain that contains the catalytic loop
#=GF CC   (Pfam:PF21654) and a C- terminal helix bundle that consists of
#=GF CC   eight helices and one pair of anti-parallel beta-sheets (this
#=GF CC   entry) [1-3].
#=GF SQ   84
#=GS A0A139SKA3_9GAMM/226-354  AC A0A139SKA3.1
#=GS A0A6N6M6Y2_9FLAO/199-326  AC A0A6N6M6Y2.1
#=GS A0A2I0R2D4_9FLAO/175-311  AC A0A2I0R2D4.1
#=GS A0A1X1MWD1_9VIBR/251-391  AC A0A1X1MWD1.1
#=GS A0A6C2D5F0_9RHOO/224-357  AC A0A6C2D5F0.1
#=GS A0A5D0VUX2_9RHOB/236-369  AC A0A5D0VUX2.1
#=GS A0A369CIJ6_9GAMM/226-354  AC A0A369CIJ6.1
#=GS A0A5C8ZS58_9GAMM/235-368  AC A0A5C8ZS58.1
#=GS Q4FRY7_PSYA2/272-408      AC Q4FRY7.1
#=GS G7M987_9CLOT/168-296      AC G7M987.1
#=GS A0A220W2X5_9SPHN/236-369  AC A0A220W2X5.1
#=GS A0A7V9Z9D0_9BACI/171-300  AC A0A7V9Z9D0.1
#=GS A0A127JUT3_9BURK/233-362  AC A0A127JUT3.1
#=GS A0A521EIH4_9BACT/179-311  AC A0A521EIH4.1
#=GS A0A3P2A1M9_9NEIS/247-378  AC A0A3P2A1M9.1
#=GS A0A2J6MTB1_9BURK/225-353  AC A0A2J6MTB1.1
#=GS A0A2S4N9A1_9FLAO/175-312  AC A0A2S4N9A1.1
#=GS A0A1G8EKR9_9RHOO/227-355  AC A0A1G8EKR9.1
#=GS A0A2R5FAD9_9PROT/225-353  AC A0A2R5FAD9.1
#=GS A0A021X2A0_9HYPH/213-348  AC A0A021X2A0.1
#=GS A4G752_HERAR/225-353      AC A4G752.1
#=GS A0A226HLQ0_9FLAO/175-313  AC A0A226HLQ0.1
#=GS A0A7Y6NNA1_9BURK/227-360  AC A0A7Y6NNA1.1
#=GS A0A7W4W9R2_9GAMM/226-354  AC A0A7W4W9R2.1
#=GS A0A5R9QEP3_9GAMM/223-351  AC A0A5R9QEP3.1
#=GS Q2NBP0_ERYLH/233-365      AC Q2NBP0.1
#=GS B1Z8T7_METPB/234-367      AC B1Z8T7.1
#=GS F0F127_9NEIS/247-378      AC F0F127.1
#=GS A0A2T5ISI5_9GAMM/240-369  AC A0A2T5ISI5.1
#=GS C0N3E4_9GAMM/239-375      AC C0N3E4.1
#=GS G3IS85_METTV/238-370      AC G3IS85.1
#=GS A0A167JAC2_9SPHN/233-365  AC A0A167JAC2.1
#=GS A0A317MN43_9GAMM/226-354  AC A0A317MN43.1
#=GS K2JN71_9GAMM/226-353      AC K2JN71.1
#=GS A0A1H1TI67_9PSED/242-373  AC A0A1H1TI67.1
#=GS A0A5S3P4C4_9SPHN/248-381  AC A0A5S3P4C4.1
#=GS A0A7Y0E3H6_9PROT/246-380  AC A0A7Y0E3H6.1
#=GS A0A3R8T0T0_9BURK/231-364  AC A0A3R8T0T0.1
#=GS A0A081FVE6_9GAMM/271-406  AC A0A081FVE6.1
#=GS A0A318EL77_9GAMM/231-362  AC A0A318EL77.1
#=GS A0A5J5FPS9_9GAMM/272-406  AC A0A5J5FPS9.1
#=GS A0A419R2X7_9SPHN/187-321  AC A0A419R2X7.1
#=GS A0A3N6MBZ2_9BURK/234-366  AC A0A3N6MBZ2.1
#=GS A0A1I7DV97_9RHOB/235-369  AC A0A1I7DV97.1
#=GS A0A2S0NGB8_9HYPH/216-350  AC A0A2S0NGB8.1
#=GS A0A845QX66_9CLOT/140-274  AC A0A845QX66.1
#=GS A0A6B3NMU5_9PSED/223-351  AC A0A6B3NMU5.1
#=GS A0A1H8TH06_9BACI/172-326  AC A0A1H8TH06.1
#=GS A0A2V4NDC5_VIBCL/276-410  AC A0A2V4NDC5.1
#=GS A0A239WMD2_9FLAO/179-309  AC A0A239WMD2.1
#=GS W0DX11_9GAMM/253-388      AC W0DX11.1
#=GS A0A4R3XM68_9HYPH/233-366  AC A0A4R3XM68.1
#=GS A0A1P8K6W2_9BURK/225-358  AC A0A1P8K6W2.1
#=GS A0A7U6KPE1_9GAMM/192-323  AC A0A7U6KPE1.1
#=GS A0A0M2WLT3_9BURK/223-354  AC A0A0M2WLT3.1
#=GS A0A1S2LCP8_9BACI/171-301  AC A0A1S2LCP8.1
#=GS A0A4R1NQD3_9GAMM/226-354  AC A0A4R1NQD3.1
#=GS A0A5B8RU13_9BURK/226-354  AC A0A5B8RU13.1
#=GS A0A3N4AJ82_9PSED/238-369  AC A0A3N4AJ82.1
#=GS A0A520FVD2_SPHSX/246-381  AC A0A520FVD2.1
#=GS A5PD54_9SPHN/233-365      AC A5PD54.1
#=GS D4E426_SEROD/272-406      AC D4E426.1
#=GS A0A4Q4XH10_9PEZI/391-518  AC A0A4Q4XH10.1
#=GS A0A1M5YDM2_9BURK/225-353  AC A0A1M5YDM2.1
#=GS A0A1X7MZ98_9HYPH/243-377  AC A0A1X7MZ98.1
#=GS A0A3B0N1U5_9RHOB/235-369  AC A0A3B0N1U5.1
#=GS I7F105_PHAIB/235-369      AC I7F105.1
#=GS A0A3A8ZKS3_9BACT/116-246  AC A0A3A8ZKS3.1
#=GS A0A4Q8UIL5_9ALTE/228-361  AC A0A4Q8UIL5.1
#=GS A0A7W8JHQ2_9GAMM/230-360  AC A0A7W8JHQ2.1
#=GS A0A516V3L8_9GAMM/230-363  AC A0A516V3L8.1
#=GS A0A6C2D4K1_9RHOO/233-364  AC A0A6C2D4K1.1
#=GS A1WRV4_VEREI/226-354      AC A1WRV4.1
#=GS A0A239I427_9PROT/230-366  AC A0A239I427.1
#=GS E5CFM1_9BACE/171-305      AC E5CFM1.1
#=GS A0A2U1CAN8_9BURK/225-358  AC A0A2U1CAN8.1
#=GS A0A1I5CTW0_9NEIS/226-354  AC A0A1I5CTW0.1
#=GS A0A0T0PQT2_9SPHN/221-356  AC A0A0T0PQT2.1
#=GS R5XYA6_9FIRM/173-302      AC R5XYA6.1
#=GS A0A3A1NYN7_9SPHN/249-383  AC A0A3A1NYN7.1
#=GS A0A846MKB5_9BACI/171-300  AC A0A846MKB5.1
#=GS DNCV_VIBCH/276-410        AC Q9KVG7.1
#=GS A0A4Q4B0R9_9BURK/226-354  AC A0A4Q4B0R9.1
#=GS F2B8M1_9NEIS/247-378      AC F2B8M1.1
A0A139SKA3_9GAMM/226-354             ....GEQFRRVIRYLKAFRDW.R.WSS...G...GPASILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAALP..A.R.LR.A..G..V...N..N..PV.DE.....S...E-S.LTER..L...GQEGVE--E...AA.K.A.F....EAFE.KALRGA...ID.A.DSP.S..QACIRMQGEFGPRFPNEPS----rvkv....
A0A6N6M6Y2_9FLAO/199-326             ..dv--QLRRIVRYLKGWGDH.L.RGE...M...PPGIIMTILAAEN...Y....VA.N....E.-R..D...DISL....RDTL.QRIQQYLS..N.N.-E.C..K..C...P..R..PT.TP.....K...DED.LFID..Y...SNSNKN--Y...FL.E.R.L....ESFI.NSANQA...IA.N.NNQ.K..DACLKWQKHLGDRFPCS------lak.....
A0A2I0R2D4_9FLAO/175-311             ..sp--QLVRIVRYLKAWKDYrE.LKN...SslkLPSGFELTILAVN...N....YT.E....D.DN..D...DFSF....RETV.RKIDKELN..K.V.NG.F..K..C...I..R..PT.TP.....K...DED.VFAD..Y...SETRK--ND...FL.K.S.L....GNLL.RDLDKA..eAE.T.NFK.K..ASEVLIKNQFGDRFPL-------gedkdq..
A0A1X1MWD1_9VIBR/251-391             gedv---CRRVCRYLKAWRDH.A.FKS...G...GPSSVALMTSVVL...S....FQ.Q....M.SR..S...RSMEklsdGEAL.LECVKCLP..D.Q.LL.N..G..I...P..N..DA.EK.....D..kGEL.LFPK..K...EMSKTEIDE...IY.E.S.A....VELH.ESLQSA...IS.A.KTK.N..DAIMKLKKSFGSRFPS-------lldllts.
A0A6C2D5F0_9RHOO/224-357             ....GEQLRRVVRYIKAYRDW.T.WKS...G...GPSSILLMAAAAP...L....FV.K....Q.DR..R...--D-....DQAL.VDVVKQLP..A.A.LR.K..G..V...S..N..PV.NP.....K...E-S.LTDR..L...RASS-TDVD...MV.E.Q.AalrfEDLG.RRLQAA...LD.A.GNA.E..QACAWLQGLFGPRFPNRP-----drvkv...
A0A5D0VUX2_9RHOB/236-369             gavy----LRLCRFYKGWRDF.I.WID...S...PLSSLCIMRAVEM...A....LN.E....F.DG..F...PSDEr..dDELI.LKVAELVP..D.Y.FD.G..K..I...S..N..PV.LT.....N...L--.-HLN..E...WEDKE-RSV...IV.K.A.A....NDLK.DEMTSA..lHR.T.GDA.E..RVVQKLRDRFGDRIPYRP-----davki...
A0A369CIJ6_9GAMM/226-354             ....GEQFRRVVRYLKAFRDW.R.WSS...G...GPASILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAALP..T.R.LR.G..G..V...S..N..PV.DD.....S...E-S.LTGR..L...GQAGVE--D...AA.K.A.F....EEFE.KVLRGA...TG.A.GST.S..QACIWMRGVFGPRFPNEPD----rvkv....
A0A5C8ZS58_9GAMM/235-368             ..gs--IFTRTCRYLKAWRDF.N.WFK...G...GPSSIALMICVWE...T....FN.D....R.KT..K...FYTD....SEAL.LAVARELP..A.R.LE.A..G..V...K..N..PV.AP.....E...E-T.VFPR..D...LDDIE-FNS...II.R.Q.T....TLFSeDIRTSL...ES.G.TSR.L..GVVETMIKHWGTRVPHRAD----wvvs....
Q4FRY7_PSYA2/272-408                 ....GRHLRKICRVIKAWRDAtD.WQE...G..nGPSSISLMAAIVD...I....AD.R....T.EL..D...TKDF....GSMM.LTVAKELP..I.V.FR.S..G..V...E..S..PD.SN.....D...ERP.LFPH..I...DDHEKKHTE...TI.S.K.L....EDLA.SSLEAA...YD.A.QTK.Q..DALNTLNSEYGNRVTNSDLIVSQ........
G7M987_9CLOT/168-296                 ....GEQVRSLVKYLKAWKDY.N.NVD...L...KGIAVTILVCE-N...Y....YS.Y....E.NR..D...DLAL....LGTV.TEIINSLE..N.E.FT.-..-..C...K..K..PV.IP.....Y...E-D.LFEE..I...DEVN--QNK...LL.E.S.L....KSLK.TEIQNA...VD.K.EDE.A..EASDIMIKVFGDRFPKGSS----tkka....
A0A220W2X5_9SPHN/236-369             ..gp--VFRRLCRFFKGWRDH.T.WEN...S...PLSSICLMCAIDA...A....LI.El.ggN.PV..D...DRD-....DMQI.MEVAKLLP..D.I.FR.G..E..I...N..N..PV.VE.....G...S-C.LNGW..-...SDADR--NE...IL.K.S.T....EALA.DEMEGA...LE.R.TGHpD..IVIDHLRNVFGRRIPNRPDII--ti......
A0A7V9Z9D0_9BACI/171-300             ....GAQLKRIVRYFKAWKDYkK.GDD...K...FPSGMIFTILAAN...H....FV.E....G.YE..E...DDD-....-SAF.VATAQEIY..D.Q.LN.S..S..F...S..LkrPV.FP.....E...EEL.LDGW..-...--SETAKTN...FL.N.K.L....SNLI.KQGQKA...LE.T.EDK.K..EAADIWRKIFGDRFPE-------ytpp....
A0A127JUT3_9BURK/233-362             ...t-EQLRRVCRYAKAWRDK.W.WTK...G...GPSSVCLMIAIAQ...K....FE.P....K.SG..R..dDLAL....EQAM.RTLAGALA..G.P.VR.E..S..V...I..G..AE.DF.....-...N-R.LDAA..E...RAA--ATQR...AS.E.T.A....EAMQ.KARM--...RR.E.DDK.Q..AAVQQLRGELGERVPMRTDLV--da......
A0A521EIH4_9BACT/179-311             ...n-EQLVRLIRYLKAWCDYrE.FSN...SsikMPSGFIMTILAIN...N....YY.S....H.ER..D...DIAL....KETL.INIQAELF..Q.E.FK.C..-..-...E..R..PT.TP.....K...GED.LFED..-...YTHEEH---...FM.K.M.L....ANFV.ERAKKA...LR.E.KNQ.K..EACKYWQKIFGDRFSCSN-----akdek...
A0A3P2A1M9_9NEIS/247-378             ....GQQLRAICRYLKAWRDW.K.FAD...Es.fQPSSILLMIIACK...H....YQ.Y....-.-H..T...SRD-....DLAL.LSVLEELP..N.A.LN.S..D..V...Y..E..NI.EE.....H...ESE.DFNR..M...KSHERP---...IA.K.QyA....DMLY.QEFVAS...LN.N.LNK.S..KALNYIKNEWGDRIPQDESLIE-t.......
A0A2J6MTB1_9BURK/225-353             ....GEQFRRIVRYLKAFRDW.Q.WVS...G...GPSSILLMAASAP...V....FD.S....R.DR..R...DDL-....--AL.LDLVDKLP..S.V.LR.D..G..V...S..N..PV.DT.....G...E-S.LTDR..L...GRDGVE--E...AA.G.K.I....ELFE.TFLRGA...LG.S.SSS.N..QACTWMIQQFGPRFPNAP-----sriki...
A0A2S4N9A1_9FLAO/175-312             ...k-EQLKRIVRYLKAWTDN.K.HHL...N...LPSGMIFTILAVN...N....YV.S....K.DR..D...DEAF....LETL.KSIQLAIDssK.N.FW.AryE..C...F..R..PTvDT.....T...ENL.LVKY..S...SETK--KKN...FL.D.A.L....DSLI.TSGNQA...IE.A.KSK.K..DACAKWQKHLGDRFPCSN-----ieekd...
A0A1G8EKR9_9RHOO/227-355             ....GEQLRRVIRYLKAFRDW.Q.WPS...G...GPASILIMAAAVP...L....FE.R....R.HG..R...DDL-....--AL.LDVLVGLP..A.A.LR.A..G..V...I..N..PV.ND.....K...E-S.LTER..L...GKDKVE--E...AA.R.E.L....QRFE.GVLRAS...LH.A.SSE.S..QVCIWMQQEFGQRFPNRP-----hrikv...
A0A2R5FAD9_9PROT/225-353             ....GEQFRRCVRYLKAWRDF.Q.WES...G...GPSSILLMAAAAL...H....FE.K....R.ER..R...DDL-....--AL.LDVVAKLP..A.A.FR.A..G..I...D..D..PV.DS.....S...K-S.LTDR..L...GTTGVK--E...VI.A.K.L....ETLE.RFLRGA...LN.A.SDS.S..QACTWVINQLGKRFPNQP-----srivq...
A0A021X2A0_9HYPH/213-348             ...q-ERLRHDCRFMKAWRDNhR.LDE...D...GLTSINIMACVWK...A....YE.V....I.RGpfL...PTRA....DERL.LRVVEKMQ..G.F.LA.N..D..V...R..I..PP.CG.....D...EN-.INRM..T...AEQR---KK...VV.G.K.L....KDLE.ATLRET..vTK.C.DDK.D..RAVDLLRAGFGSRVPKR------pdlviiq.
A4G752_HERAR/225-353                 ....GEQFRRVVRYLKSFRDW.Q.WVQ...G...GPSSILLMAAAAP...L....FE.S....R.DR..R...DDL-....--AL.LDLLDNLP..D.A.LR.Q..G..V...L..C..PT.DP.....N...E-S.LTDR..L...GQPGVE--D...AA.H.K.L....EQLE.KSLRGA...IH.A.SSP.S..QALIWVREQFGPRFPNAPER---vkv.....
A0A226HLQ0_9FLAO/175-313             ..ks--QLKRIVRYLKAWTDN.K.SRL...K...LPSGMIFTILAVN...N....YQ.P....N.DK..D...DVAF....LDTL.EKIQKSID..DtR.FTwT..G..VyecK..R..PT.VD.....D...TEN.LLEK..Y...SSET-SKKN...FL.D.A.L....NSLI.DSGRQA...IN.L.KSK.K..DACAKWQKHLGDRFPCSN-----ikend...
A0A7Y6NNA1_9BURK/227-360             ....GEQLRRVVRYLKAHRDW.R.WTS...G...GPASILLMAAAVP...L....FA.K....H.D-..-...RRD-....DLAL.LKVVKGLP..A.V.LR.N..G..V...N..N..PV.DT.....S...E-S.LTDR..L...RKAS-KERD...LV.E.E.AalafERLG.SLLEGA...LA.A.SNA.A..QACEWMRQAFGPRFPD-------cpervkv.
A0A7W4W9R2_9GAMM/226-354             ....GEQLRRVVRYLKAFRDW.R.WSS...G...GPASILLMAAASP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAVLP..A.R.LR.A..G..V...D..N..PV.DE.....S...E-S.LTER..L...GKTGVE--E...AA.K.A.F....EELE.KVLRGA...TD.A.GSP.S..QACIWMQGEFGPRFPNEPD----rvkv....
A0A5R9QEP3_9GAMM/223-351             ...e-EQLRRVIRYIKAFRDK.Q.WDK...G...GPSSILLMAAACP...L....FE.F....Y.SK..R...DDL-....--AL.LHVVKGLP..A.A.LR.N..G..V...K..S..PV.DS.....K...V--.-YLT..D...ALGEEGVTE...AA.K.K.F....ETFR.TYLEAS..tAE.S.AKK.D..MACQWMCAMLGDRFPNR------pdlip...
Q2NBP0_ERYLH/233-365                 ...g-PSFRRMSRFFKGWRDH.V.WAN...S...PLSSICLMCAIDA...A....LL.El..gQ.SA..D...NRD-....DKTI.LDVARLLP..Q.I.FS.G..E..I...K..N..PV.VK.....A...S-C.LNS-..W...SEEE--RGA...IL.A.E.T....RALT.ETMEAA..lER.T.GNA.D..RVIEHLRDAFGRRIPYRPD----viti....
B1Z8T7_METPB/234-367                 ...g-AVYRRLSRFFKGWRDF.T.WER...S...KLSSLCLMCA-VD...LalrqLD.G....L.PT..E...NRD-....DELV.LEVAKRLP..D.I.LN.G..K..I...M..N..PV.LG.....-...--H.LCIN..E...WDNEVR-GE...IL.E.G.A....EKLRiQMIAAL...ER.T.GDA.E..QVVLKLRARFGHRIPYRPDV---vti.....
F0F127_9NEIS/247-378                 ....GQQLRAICRYLKAWRDW.Q.FAD...Ks.fQPSSILLMIIACK...Y....YQ.Y....H.QH..R...DDL-....--AL.LSVLEKLP..N.A.LN.D..N..V...Y..E..NI.EE.....H...ESE.DFNR..M...EEYE--RVE...AS.Q.Y.A....DALY.QSFMAS...LN.N.LDK.T..KVLNFITNEWGDRIPQDENLIE-t.......
A0A2T5ISI5_9GAMM/240-369             ....GQQLKAIVRYLKGWRDQ.H.WKE...G...GPTSILLMIITVQ...H....YK.Y....A.--..D...SRD-....DQAL.FTVTQNLA..T.S.LK.N..E..V...Y..A..SI.DE.....H...EEK.DFNS..A...TPQQ--RLE...YA.N.K.A....KELH.TYVEQS...ML.A.ETP.N..ASVDYLRASFGQRLPNEPKL---vit.....
C0N3E4_9GAMM/239-375                 ....GSMIRPVNRFLKAWRDH.A.WPD..gG...GPSSIFLLAHSLH...S....FP.S....D.TN..G...LSH-....CEAL.EAVINELP..S.V.FN.R..PllV...P..R..PT.ST.....DkfaKED.LCER..I...SDEEKK--E...FY.T.Y.F....ESLR.QQYALA...KR.T.DPR.-..AANSILISIFGRRMPNDP-----srivv...
G3IS85_METTV/238-370                 ....GDRLVRVCRYLKAWRDF.T.WEK...G...GPTSITLMACAAS...V....FD.N....S.NG..F...NRD-....CEAL.FAVAKKLP..E.L.FS.G..E..I...K..N..PA.ES.....E...E-T.LYPR..E...LTQEVI-VD...IV.N.K.A....EIFR.DTLTEA..lIH.A.ENS.Q..EVVDLFIRSLGSRIPNDSTYIT-p.......
A0A167JAC2_9SPHN/233-365             ...g-PAFRRMSRFFKGWRDH.V.WAN...S...PLSSICLMCAIDA...A....LL.El..gQ.SA..D...NRD-....DKTI.LDVARLLP..R.I.FS.G..E..I...K..N..PV.VK.....A...S-C.LN-S..W...SEEE--RGD...IL.A.E.T....QALA.ATMEAA..lER.T.GDA.D..RVIEHLRDAFGRRIPYRPDII--ai......
A0A317MN43_9GAMM/226-354             ....GEQFRRVIRYLKAFRDW.K.WPS...G...GPASILLMAAAAT...L....FE.K....R.DR..R...DDL-....--AL.LDVVAALP..A.R.LR.A..G..V...N..N..PV.EE.....S...E-S.LTER..L...GKAGVE--E...AA.K.A.F....EEFE.KVLRGA...TG.A.GSP.S..QACIWMRGEFGPRFPNEPD----rvkv....
K2JN71_9GAMM/226-353                 ....GEQFRRVVRYLKAFRDW.R.WSE...G...GPASILLMAAAAP...L....FE.K....R.DS..R...--D-....DLAL.QGVVDALP..A.R.LR.A..G..V...N..N..PV.EP.....S...E-S.LTNR..L...GKEGVE--E...AA.R.A.F....EAFS.EVLRGA...ID.A.GNP.A..QACTWMQGQFGPRFPDE------pgrvr...
A0A1H1TI67_9PSED/242-373             ....GEQFLRVCRYVKAWRDF.N.WKT...G...GPTSVSLMIAIAQ...G....FE.G....K.KG..R...DDIA...lEQAA.TVVAQAVR..D.DiYE.H..G..I...D..N..--.GT.....E...D--.-FN-..I...LTQDKR-IE...AG.L.A.A....DRLV.SNLRSS...RS.A.ASH.QglSVLNTLRTVLGERIPFSPELI--qe......
A0A5S3P4C4_9SPHN/248-381             ....GQQLRRVCRYLKGWRDH.N.WTA...C...RLSSIALMACVVA...A....YD.E....A.TA..A...IAENr..dDLAL.QMVAKRLP..E.L.LE.R..S..I...P..N..PV.VH.....G...Q--.-YLD..E...GWTGECRAD...FI.A.K.A....HDLA.TRIDVA...LA.S.NQS.G..TVIEHLRASLGTYLPDNEDL---vvi.....
A0A7Y0E3H6_9PROT/246-380             ....GEVVRRICRYLKGWRDY.Q.WPK...D...GPSSITLMACVVT...V....FD.D....L.NG..TlpkNRD-....DLAL.QAVSHRLE..E.L.FS.Q..P..I...A..N..PV.LP.....D...Q-I.LDES..W...SPEE--RID...FK.S.H.A....AKLK.AVIDGV..lNG.T.FHK.Q..IALSLLQERFGDRIPNDELLI--ei......
A0A3R8T0T0_9BURK/231-364             ...t-DQLRRVCCYLKAWRDL.H.WKA...G..dGPTSVCIMVAVAQ...K....FE.A....I.RG..R...DDL-....--AL.EAASKTLA..N.A.LR.G..D..I...R..A..PG.ID.....E...GKE.DFNK..R...LNPAQREEAsamAI.T.L.A....QQIQ.AARLKP...L-.-.HAP.G..DAIDIIQSQLGLRIPMRTDLI--ep......
A0A081FVE6_9GAMM/271-406             ....GIHLRVLCRILKAWRDV.Q.WDK...G...GPSSICLMKCAVD...T....LR.R....N.PH..D...GSDL....GETL.RLLASHLP..N.Q.LL.E..G..V...R..S..PD.PT.....D..gDRL.LFPS..A...NEHSRKETE...IV.E.R.A....RDLT.STLERA...LV.T.DTK.S..EALRILQTLFGSRVTNEELIKH-r.......
A0A318EL77_9GAMM/231-362             ....GEQLQRICRYVKAWRDF.H.WTT...G...GPSSILLMIIVAR...G....FV.P....N.PR..R...DDL-....--VL.EEAAARLA..S.E.LR.G..N..V...Y..E..RA.IG.....D...GTE.DFNR..L...SATER--TF...AA.D.A.A....ASLR.AALRQAr.gRS.A.VQK.A..EAINDLRRQLGDRIPFIED----wvel....
A0A5J5FPS9_9GAMM/272-406             ....GGHLRSICRFMKAWRDA.Q.WEV...G...GPSSISLMTAVVN...I....LD.R....E.DH..N...GSDL....TETM.KLVARLLP..D.E.FC.S..G..L...E..S..PD.DT.....D...DKL.LFPA..E...CDHNVHQRT...IV.E.T.M....RSLQ.GILLDA...ES.S.GSR.E..DALHKMNEAFGKRVTNASLITS-i.......
A0A419R2X7_9SPHN/187-321             ..rt--KVRRQVRYLKMWAAL.T.FAE...G..sRPSSILLTVLVAD...A....VR.E....M.DL..T...STDD....ADLF.ESIAAVVH..A.R.LA.D..G..A...K..V..PN.PV.....D...IGE.DLNR..L...SDAE--HAE...FV.A.Q.L....ETLV.DVAARA...NG.A.QDK.F..TAAETWTEAFGHFFPM-------pedneemv
A0A3N6MBZ2_9BURK/234-366             ....GAQLQRVCRFLKAWRDY.R.WEK...K...GPTSVSIMIAVAQ...D....FE.-....-.PV..F...GRD-....DLAL.EQAARLLA..K.A.LL.T..D..I...R..E..PG.ID.....N...GVD.DFNR..S...LDSAAR-LE...AS.T.F.A....QNLA.DSLRQAr.eLS.L.VQA.P..WAVAVLQAQLGGRLPNQPNWV--ev......
A0A1I7DV97_9RHOB/235-369             ....GEQVRTVSRYLKGWKDF.Q.WPE...G...RLASIALMAAVVS...V....FE.K....A.SA..A..iASDR...dDLAL.LRVAEDLP..D.F.LA.N..G..I...P..N..PV.VE.....G...AR-.LDQG..W...SPEE--RRD...FV.A.K.A....RVLA.ERLKDA..lTQ.T.SDR.A..AAFEALQNQFGGRIPDDLT----lyvp....
A0A2S0NGB8_9HYPH/216-350             ....GERLRRDSRYLKAWRDY.QrLER...L...KVSSILLMACVWH...A....YG.E....I.GG..R...ELPPr..eDERL.LRVVELMP..G.F.LR.G..T..V...Q..N..PA.CT.....E...EDLnRIPE..E...SR-----DE...VA.D.A.F....EGLA.AVLRTV..vDN.C.EDA.R..EAVRLLRRAFGARVPDR------pdlvsi..
A0A845QX66_9CLOT/140-274             .gef----CRIAKMIKYWRDT.K.VGK..dT...APKSILLTTIIGE...N....MV.G....K.NS..D...AESL....VETL.ENIVENID..N.I.IN.E..E..T...D..Q..PY.VE.....N...P-S.LEGEnlA...RDWNREKFD...IF.KiK.L....EKFT.KDSRDA...LE.E.NDE.D..KSIEKWQDIFGTTFPS-------qlseg...
A0A6B3NMU5_9PSED/223-351             ....GDQLIRVVRYLKAFRDK.Q.WED...K...GPSSILLMAAACP...L....FE.Y....F.DK..R...D---....DRAL.LNVVKGIP..D.A.LR.N..G..V...A..S..PI.DA.....T...A-S.LTAH..M...PKEA--IAD...AV.E.F.F....QEFA.RYLEGA...IN.A.TDA.D..TAYNWLHQMLGDRFPYAP-----hrmts...
A0A1H8TH06_9BACI/172-326             ..rk--QFRRIVRFLKRWKDN.T.FSSv.nG...KPTGISLTSCAYHwlsI....QK.E....T.DL..F...SGVTtykdLDAL.ICVVSIMI..S.N.FR.E..E..L...V..L..ID.EEytwvsRlkvELP.VEPK..PdlfEKMTSKQME...TFkS.K.L....ETFL.EALEEA...KA.A.TDP.T..DAAELLEKQFGSDFPI-------psksst..
A0A2V4NDC5_VIBCL/276-410             ....GKHLRKVCRFMKAWRDA.Q.WDV...G...GPSSISLMAATVN...I....LD.S....V.AH..D...ASDL....GETM.KIIAKHLP..S.E.FA.R..G..V...E..S..PD.ST.....D...EKP.LFPP..S...YKHGPREMD...IM.S.K.L....ERLP.EILSSA...ES.A.DSK.S..EALKKINMAFGNRVTNSELIV--la......
A0A239WMD2_9FLAO/179-309             ...d-EQLRRIVRYFKAWRDK.Q.MQD...SditLPPGIILTILVSN...N....YV.K....N.DR..D...DISL....QETL.QKIKNELD..I.N.Y-.-..V..C...Y..R..PT.TK.....K...DEE.LLKD..-...----YDKTH...FL.D.R.L....SKFI.ESANEA...VN.H.SSQ.K..EACKKWQKHLGERFSCSN-----ikeen...
W0DX11_9GAMM/253-388                 ....GEGLRRVCRYLKAWRDH.T.WED..gG...GPSSISLMACAVN...T....YN.D....P.QN..S...SGFAg..dSEAL.LAVVTALP..T.Q.LN.E..G..V...Y..L..--.MT.....K...NEM.LYPR..E...SDQK-NHSE...IV.S.Q.A....EKLKtNIRRSL...LS.A.ESQ.E..ECVSGFMAIFGSRFPYDTESVE-s.......
A0A4R3XM68_9HYPH/233-366             ..ga--VYKRLCRFFKGWRDY.I.WLK...S...PLSSLCIMCAVDQ...A....LQ.K....L.NG..F..pTEDR....DDALiLEIAKELP..D.L.FN.G..K..I...E..N..PV.LK.....-...--H.LCIN..E...WSEEDR-DA...IV.S.A.A....RELR.DEMSSA..lER.T.GDA.E..LVVKKLRNKFGQRMPYRPDS---vkm.....
A0A1P8K6W2_9BURK/225-358             ....GEQLRRVVRYLKAYRDW.T.WDK...G...GPSSILLMAAAAP...L....FV.R....Q.DR..R...DD--....-QAL.LDVVKLLP..A.V.LR.K..G..V...N..N..PI.NP.....E...E-S.LTDR..L...RASS-DDAD...MV.E.Q.AalqfEDLG.SRLQAA...LD.A.GNA.E..QACSWLRDLFGPRFPNRPE----rvkv....
A0A7U6KPE1_9GAMM/192-323             ....GQQLRAVIRYLKSWRDY.N.QYQ...K...APSSVSLMIIATE...H....YQ.H...lQ.QR..D...DRAL....FEIL.LNLEHALK..N.D.IK.C..K..Y...I..E..GH.ST.....E...D--.-FNR..A...NNEQRE--E...NA.E.L.A....SELC.SGFDRV..lHK.S.QNE.N..TCLNILESLFGERIPSN------rpdlvt..
A0A0M2WLT3_9BURK/223-354             ....GDQLAHVCRYMKAWRDF.H.WED...A...GPSSVCLMIAISQ...K....FQ.R....Q.PG..R...DDL-....--AI.EKAAEHLA..T.A.IR.F..D..I...R..E..VA.ID.....D...RLE.DFNR..L...DPMGRG--F...AA.Q.K.A....TELQ.NSLFQAr.tWS.I.GLK.S..NAIASLRRVFGQRIPDDQNLIE-q.......
A0A1S2LCP8_9BACI/171-301             ....GDQLKRIVRYLKAWKDFkK.GDD...K...FPSGMVFTILAAN...Y....FI.E....G.YE..D...DDD-....-AAF.VAIAKEIY..N.N.LN.S..S..F...SltR..PV.FP.....D...EEL.LADW..S...---ETAKTN...FL.S.K.L....STLV.TNGQKA...LE.K.DKQ.S..DASDIWIKIFGERFPK-------pnppe...
A0A4R1NQD3_9GAMM/226-354             ....GEQFRRVVRYLKAFRDW.K.WSS...G...GPSSILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAAMP..T.R.LG.T..G..V...N..N..PI.DE.....T...E-S.LTNR..L...GKEGVQ--E...AI.K.A.F....EDFE.KVLRGA...VD.A.GSC.S..QACIWMCSEFGPRFPNEPD----rvkv....
A0A5B8RU13_9BURK/226-354             ....GEQFRRVVRYLKAFRDW.R.WSS...G...GPASILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAALP..A.R.LR.A..G..V...N..N..PV.EE.....S...E-S.LTAR..L...GKAGVE--E...AA.K.A.F....EEFE.NVLRGA...TD.A.GSP.S..QACIWMRGEFGPRFPNDPDR---vkt.....
A0A3N4AJ82_9PSED/238-369             ....GEQLRRVCRYLKGWRDF.H.WTS...G...GPTSVSIMIAAAQ...K....FE.P....R.PR..R...DDI-....--AL.EETSRHLS..Q.M.FL.S..D..I...H..E..EG.ID.....N...GQE.DFNR..L...SEEDRR--L...AS.T.R.F....RTLA.STMQELr.sIH.E.TQK.L..DVIRQLRGQFGARIPNDISL---iev.....
A0A520FVD2_SPHSX/246-381             ..gp--IIRELSRSFKALRDL.K.FDT...-...GLSSICIMACVVR...A....VE.R....IgPP..D...AKRL....DLAL.VHVGREIG..R.M.IE.Q..P..V...Q..N..PV.FP....gD...ASK.YFCT..G...WTPEYR-AK...VR.A.L.F....VDAA.DEMEEA...IDgT.FHR.T..VALGRARRAFGSRVPDREDL---ira.....
A5PD54_9SPHN/233-365                 ...g-PSFRRMSRFFKGWRNH.V.WAD...S...PLSSICLMCAIDA...A....LL.El..gQ.SA..E...NRD-....DKTI.LDVARLLP..P.I.FS.G..E..I...K..N..PV.VK.....A...S-C.LN-S..W...SEEE--RGD...VL.A.E.T....RALA.ATMEAA..lER.T.GDA.D..RVIEHLRDAFGRRIPYRPDII--ai......
D4E426_SEROD/272-406                 ....GGHLRSVCRFMKAWRDA.Q.WEV...G...GPSSISLMTAVVN...I....LD.R....E.SH..N...GSDL....TGTM.KLIARLLP..E.E.FN.R..G..V...E..S..PD.DT.....D...EKP.LFPA..E...SNHNVHHRA...IV.E.T.M....EGLY.GILLAA...EQ.S.VSR.E..EALRKINEAFGKRVTNALLITS-s.......
A0A4Q4XH10_9PEZI/391-518             ....GPQLLRVCRFLKAWRDY.R.WAE...K...GPTSVSIMIAVAQ...S....FT.P....V.SG..R...DD--....-LAL.ELAAHSLA..K.A.LL.A..D..I...R..E..PG.ID.....N...GED.DFNK..R...LSEKE-RLE...AS.A.L.A....QALA.NSMREAr.eQN.L.VQA.E..RAILILQGGYG------------ralsvlt.
A0A1M5YDM2_9BURK/225-353             ....GEQFRRVVRYLKAFRDW.R.WPS...G...GPASILLMSAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVALLP..A.R.LH.A..G..V...N..N..PV.DE.....S...E-S.LTKR..L...GKTGVE--E...AA.K.A.F....EEFE.RVLRGA...IG.A.GSR.S..QACIWMQGEFGSRFPNEPD----rvkv....
A0A1X7MZ98_9HYPH/243-377             ....GPQLRRTCRYLKGWRDF.L.FLE...G...GPASIALMACAVR...S....YK.EggwvP.QN..D...RDD-....-LAM.LEIAKRLP..V.F.FS.A..T..I...V..N..PV.LP.....D...AEP.L---..N...DWDEVTRKR...FV.N.A.A....NDLH.GHMHTA..lEG.T.ANA.E..ITVRRLQEALGTRVPYRPD----lvra....
A0A3B0N1U5_9RHOB/235-369             ....GEQVRTVSRFLKGWKDF.Q.WPE...G...RLASIALMAAVVS...V....FE.K....A.SA..A..iAGDR...dDLAL.LRVAEDLP..D.F.LA.N..D..I...P..N..PV.VE.....G...ERL.DQGW..-...SAEE--RSD...FV.T.K.A....RLLA.ERLADA..lTQ.T.SDR.A..MAYEALQEQFGGRIPDDLT----lyvp....
I7F105_PHAIB/235-369                 ....GEQVRTVSRYLKGWKDF.Q.WPE...G...RLASIALMAAVVS...V....FE.K....A.SA..A..iASDR...dDLAL.LRVAEDLP..D.F.LA.N..D..I...P..N..PV.VE.....G...ARL.-DQG..W...SPEE--RSD...FV.A.K.A....RVLA.ERLKDA..lTQ.T.SDR.T..AAFEALQNQFGGRIPDDLT----lyvp....
A0A3A8ZKS3_9BACT/116-246             ....GQQIRRLVKYLKAWKDY.K.GID...V...KGMALTILVCRNF...N....LT.E....-.NR..D...DISL....LDTV.TNIIDSIE..E.D.FH.-..-..C...Y..K..PV.TP.....T...DED.LFSD..T...SETSKN--A...IL.N.G.L....NNLK.KKLDTA..iYE.E.KNE.K..EATDILQKVFGIRFPEGE-----dfdks...
A0A4Q8UIL5_9ALTE/228-361             ..pf---LRNVCRYLKAWRDF.E.WQE...G...GPSSIMLMVAAVK...A....LE.Q....F.AK..T...PDSE....CEAL.LVVTQALP..T.I.FA.A..E..I...N..N..PT.DD.....N...E-N.MFPS..R...CKDEADVED...IR.T.R.I....AGLS.LRYSQA..vCA.S.STK.Q..SAVNALIALLGQRLPNREDWV--ke......
A0A7W8JHQ2_9GAMM/230-360             ....GDQLQRVWRYVKAWRDH.N.WQE...G...GPTSVLLMLAICR...H....FS.K....Q.PG..R...DD--....-KAL.AHVAQFIP..A.A.VA.G..D..Y...Y..E..-E.GI.....D...SEH.NFNR..L...DATQ--RLD...AR.N.R.A....ILLE.RALRESl.tNV.T.QPK.S..AVVIALRGQLGQRIPNREADV--et......
A0A516V3L8_9GAMM/230-363             ....GPQLRRVCRYVKGWRDY.Y.WPD...C..dGPSSVSLMILVAR...N....FVpR....L.RR..D...--D-....-LAL.EDAARAIY..E.G.IG.H..D..I...Y..E..PG.ID.....G...GET.DFNR..L...DATQRKVA-...-K.A.Q.A....KDLL.DQLSNSrhyAS.L.NLA.R..DAIRNVRGQFGSRIADDIS----fiel....
A0A6C2D4K1_9RHOO/233-364             ....GPQLRRVCRCLKAWRDY.Q.WQQ...G...GPTSVSIMIAVAQ...G....FE.P....R.AG..-...-RD-....DRAL.EDAARRLS..R.A.FL.G..E..I...R..E..PG.ID.....D...GVE.DFNR..L...QEADRE--A...AA.Q.L.F....GRLA.AQLFQA..rES.AlHEK.E..VVVARLRQQFGERLPMDSTRV--ef......
A1WRV4_VEREI/226-354                 ....GEQFRRVIRYLKAFRDW.R.WSS...G...GPASILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LAVVAALP..A.R.LR.A..G..V...N..N..PV.DE.....S...E-S.LTVR..L...GKEGVE--E...AA.K.A.F....EALE.KVLRGA...TD.A.GSP.S..QACIWMQGEFGPRFPNEPD----rvkv....
A0A239I427_9PROT/230-366             ....GDELRRACRYLKAWRDF.N.HAK..iG...AVSSILLMACAAA...V....FD.K....N.AR..V...MPKR...dDEVL.LKIATELP..T.L.LS.G..A..V...A..N..PA.DP.....D..sGED.LTAK..L...DDAA-RK-A...AV.V.A.A....YDLH.RVLSDV..iNK.C.HIQ.Q..SVVNHVQSLFGNRVPNRPD----lvkv....
E5CFM1_9BACE/171-305                 ..hp--QLRRVVRYLKAWADY.V.DDStskK...MPTGCALMMLAVE...H....YK.A....N.DR..D...DIVL....RDIL.VSMHESLS..K.E.DG.F..H..C...Y..R..PT.FP.....K...NED.LFDG..Y...SATRKK--D...FL.A.E.L....KSFK.EDAERA...VN.S.KNP.H..DACLKWQNHFGDRFCCS------takde...
A0A2U1CAN8_9BURK/225-358             ....GEQLRRVVRYLKAYRDW.T.WKS...G...GPSSILLMAAAAP...L....FV.K....Q.DR..R...--D-....DQAL.LDVVKQLP..T.A.LR.S..G..V...S..N..PI.NP.....Q...E-S.LTDR..L...RASD-DEVD...MV.E.Q.AalqfEGLG.RQLQAA...LD.A.GSA.A..QACTWMQGLFGPRFPDR------pdrvkv..
A0A1I5CTW0_9NEIS/226-354             ....GEQFRRVVRYLKALRDW.R.WSS...G...GPASILLMTAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVALLP..A.R.LR.A..G..V...N..N..PV.DE.....S...E-S.LTER..L...GEAGVE--E...AA.K.A.F....EEFE.KVLRAA...TD.A.GSP.S..QACIWMQDEFGPRFPNAP-----drvkm...
A0A0T0PQT2_9SPHN/221-356             ....GPDFRRVCRYLKGWRDQ.R.WAK...P...CLTSITLMVAVEK...A....LG.M....L.NG..G...HRALp..dDHLL.YEVAQRLP..G.I.LR.G..E..L...L..N..PV.FP.....G...QRI.ILND..W...SPEDR--DA...VI.G.S.A....EALA.ADLHSA...LKgT.HDA.T..LVVESLRRALGTRIPYRPD----avem....
R5XYA6_9FIRM/173-302                 ....GQEIRRMVKYLKAWKDY.K.NID...I...KGMAITILVCNNF...C....VT.-....E.KR..D...DLSL....LDTV.TNIIDSLE..D.S.FH.-..-..C...Y..K..PV.TP.....T...DED.LFAD..V...SETSKN--E...IL.K.G.L....NNLK.KKLDAA..iNE.N.NNE.K..DATDILQKVFGERFPTG------edadk...
A0A3A1NYN7_9SPHN/249-383             ....GEQVRRLSRYLKGWRDH.R.WEK...C...RLSSIALMACVVR...Y....FE.E....A.GA..Sv.pARD-....DASL.AELTRKLP..Q.Y.LR.G..E..I...R..N..PV.VQ.....G...R-L.DEGW..D...DGNAPLRPG...FV.Q.C.A....EELR.DDVAAA...LA.A.TDR.T..NAKNRLCRIFGMHFPDDPAL---iei.....
A0A846MKB5_9BACI/171-300             ....GAQLKRIVRYFKAWKDYkK.GND...K...FPSGMIFTILAAN...H....FV.E....G.YE..E...DDD-....-SAF.VATAQEIY..D.Q.LN.S..S..F...S..LkrPV.FP.....E...EEL.LDGW..-...--SETAKTN...FL.N.K.L....SNLI.KQGQKA...LE.T.VDK.K..EAADIWRKIFGDRFPE-------ytpp....
DNCV_VIBCH/276-410                   ....GKHLRKVCRFMKAWRDA.Q.WDV...G...GPSSISLMAATVN...I....LD.S....V.AH..D...ASDL....GETM.KIIAKHLP..S.E.FA.R..G..V...E..S..PD.ST.....D...EKP.LFPP..S...YKHGPREMD...IM.S.K.L....ERLP.EILSSA...ES.A.DSK.S..EALKKINMAFGNRVTNSELIV--la......
A0A4Q4B0R9_9BURK/226-354             ....GEQFRRVVRYLKAFRDW.R.WYN...G...GPASILLMAAAAP...L....FE.K....R.DR..R...DDL-....--AL.LDVVAALP..A.R.LR.A..G..V...N..N..PV.DV.....S...E-S.LTAR..L...GEEGVE--D...AA.K.A.F....EELE.NVLRGA...TD.A.SSP.S..QACIWMQGEFGPRFPNEPD----rvkv....
F2B8M1_9NEIS/247-378                 ....GQQLRAICRYLKAWRDW.Q.FAD...Ks.fQPSSILLMIIACK...Y....YQ.Y....Y.QH..R...DDL-....--AL.LSVLEKLP..N.A.LS.G..N..V...Y..E..NI.EE.....H...ESE.DFNR..M...KEGE--RVE...AM.Q.Y.A....DALY.QNFMAS...LN.N.FDK.T..KALKFITNEWGNRIPQDEDLI--et......
#=GC seq_cons                        ....GpQlRRlsRYLKAWRDa.p.Wps...u...uPoSIhLMssssp...h....ap.c....p.sp..c...sps.......AL.hplsctLP..s.t.lp.s..s..l...p..s..Ps.ss.....s...c.p.Lhsc..h...sppp.p..-...hh.p.t.h....csLt.ptlpsA...hs.s.ssp.p..pAsphlpptFGsRhPsp......hh......
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