#=GF ID   Dsl1_N
#=GF AC   PF11988.12
#=GF DE   Retrograde transport protein Dsl1 N terminal
#=GF AU   Gavin OL;
#=GF SE   pdb_3etu
#=GF GA   25.00 25.00;
#=GF TC   36.80 29.70;
#=GF NC   23.00 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Repeat
#=GF CL   CL0020
#=GF RN   [1]
#=GF RM   19151722
#=GF RT   Structural characterization of Tip20p and Dsl1p, subunits of the
#=GF RT   Dsl1p vesicle tethering complex.
#=GF RA   Tripathi A, Ren Y, Jeffrey PD, Hughson FM;
#=GF RL   Nat Struct Mol Biol. 2009;16:114-123.
#=GF RN   [2]
#=GF RM   11493604
#=GF RT   The coatomer-interacting protein Dsl1p is required for
#=GF RT   Golgi-to-endoplasmic reticulum retrieval in yeast. 
#=GF RA   Andag U, Neumann T, Schmitt HD; 
#=GF RL   J Biol Chem 2001;276:39150-39160.
#=GF DR   INTERPRO; IPR021875;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   Dsl1 is a peripheral membrane protein required for transport
#=GF CC   between the Golgi and the endoplasmic reticulum [1]. It is
#=GF CC   localised to the ER membrane, and in vitro it specifically binds
#=GF CC   to coatomer, the major component of the protein coat of COPI
#=GF CC   vesicles [2]. It is comprised primarily of alpha helical bundles
#=GF CC   [1]. It complexes with another subunit of the Dsl1p complex
#=GF CC   called Tip20 which forms heterodimers by pairing the N termini
#=GF CC   of each protein [1].  A central disorganised region between the
#=GF CC   N and C termini of Dsl1 contains binding sites for coatomer [1].
#=GF CC   The C terminus of Dsl1 contains a binding site to the Sec39
#=GF CC   subunit of the Dsl1p complex [1].
#=GF SQ   30
#=GS A0A1G4JZV3_9SACH/23-369  AC A0A1G4JZV3.1
#=GS A0A7H9AV59_ZYGMR/16-366  AC A0A7H9AV59.1
#=GS Q6FNZ0_CANGA/3-351       AC Q6FNZ0.1
#=GS A0A1U7EQB3_9SACH/20-370  AC A0A1U7EQB3.1
#=GS A0A0C7N2K0_9SACH/24-368  AC A0A0C7N2K0.1
#=GS Q752C3_ASHGO/45-390      AC Q752C3.1
#=GS G8ZQK5_TORDC/17-366      AC G8ZQK5.1
#=GS A0A1E5RGU1_9ASCO/23-406  AC A0A1E5RGU1.1
#=GS A0A4C2E9S2_9SACH/12-364  AC A0A4C2E9S2.1
#=GS A0A1G4JWI2_9SACH/21-364  AC A0A1G4JWI2.1
#=GS A0A1V2L1Q6_CYBFA/15-195  AC A0A1V2L1Q6.1
#=GS G0WD68_NAUDC/10-396      AC G0WD68.1
#=GS J8Q396_SACAR/5-358       AC J8Q396.1
#=GS A0A1E3P269_WICAA/26-203  AC A0A1E3P269.1
#=GS A0A1S7HMD7_9SACH/12-362  AC A0A1S7HMD7.1
#=GS Q6CUS2_KLULA/12-352      AC Q6CUS2.1
#=GS A0A376B2R6_9ASCO/21-405  AC A0A376B2R6.1
#=GS J7S867_KAZNA/6-376       AC J7S867.1
#=GS I2GW53_TETBL/22-390      AC I2GW53.1
#=GS A0A1E4RZ31_CYBJN/18-178  AC A0A1E4RZ31.1
#=GS H2AUI4_KAZAF/5-354       AC H2AUI4.1
#=GS C5DK93_LACTC/23-365      AC C5DK93.1
#=GS G8BQ21_TETPH/10-363      AC G8BQ21.1
#=GS K0KHW4_WICCF/11-177      AC K0KHW4.1
#=GS A0A7H9HNE0_9SACH/16-365  AC A0A7H9HNE0.1
#=GS G0V593_NAUCC/12-369      AC G0V593.1
#=GS A7TF57_VANPO/11-362      AC A7TF57.1
#=GS A0A1X7R2M1_9SACH/5-355   AC A0A1X7R2M1.1
#=GS A0A1G4MGQ1_LACFM/21-362  AC A0A1G4MGQ1.1
#=GS DSL1_YEAST/5-360         AC P53847.1
A0A1G4JZV3_9SACH/23-369             ..................vc--DQERILESIEKD....SNLAL...RDNESKv............lhQQVTDVPRLLAHDAGLSKQLGTYQGLSVISDLLDEFSVNFQLWELENCFHSLHNVHRRLQ......NLD-SGTL.PL....QFQESLKLHVNTLHLDLLTRCEEVMQQ-MWTI........E.SDSITFNISI...KAGPDQTVIEYLPIREFLDTCLF..............PDGRF..ET..........TFWFVSSLGVTD.IKDTVITKLSKLYGLYIGLQEIQGQ.LKSFLFATGAYLETQD---.....NCSLRK..........IPRHCNAGETIRSFEAIVSFLSEIIWRG.DANTILARLGSTLVVEIIKFSKQNSRQVLGSDTGY-.KEQILNLNNQLKVMSVN..........SN.GVWPY...DGRELDSILHDDSVIINLMLDKLLQRQLVKIR........................
A0A7H9AV59_ZYGMR/16-366             ....................LGDNDKLLRELKND....KLLEE...YLNSNR...............ENGHNSSDILSREQELSKELHELSRLRSIPGLVLEIETNLELQEFENCYQSLKTLRKKLY......ENEFILNK.SF....GLQQSVSRFVDGLHVKFVHQVHEVCKA-FWKV........Q.DDSIALHKRI...KWGKDDVEIEYSAFIESVATLFF..............PEGLV..DS..........KHWIIDDMLLAD.LQENVRATLKSIFNDHIHLDVIVEK.MKSLIFVGKKEIAFSDDKDf...lILKGVY..........IGNEETTAGTLSNFESILLFLDHTSPPG.AKSVLVRRLCPVLANDLLKVIKKNASGVFGPQESSV.KKKALRVNCLLEKLLNS..........QE.DMSKA...IASEIERLLTSEELYVHLQLEKIFQEQLQELR........................
Q6FNZ0_CANGA/3-351                  ....................YADKDHVITELLKD....PVYLS...RHNSLA...............THPKDENDLYALETKLEEELHDLKDLKIVSSLVKETQVNLDLMELENCYYSLYNLSKKLK......SSRSFLKQ.SL....HFQRSVAVHVDELRIKLLSTIYDILATKFWSI........S.ESSFEFHPDI...KWKEEEFMMKYEEFKSFVSKSFF..............PDNAI..NN..........SHWLITDIIHSE.EQERMRNKLKDIYINYIDFASLTKA.VKDALFSDEYEFEWSDNNY.....TKLLIT..........KRGALCIQKRIESFNNLLSFLEKGISNS.DKFKLLTNLGKAIGIEFLRFVKSNATGIIDKNANSI.KQQTLLLNDRLKTISEQ..........-S.GAWNF...DSDQISKLLNDEILYKSLLLDGVLGRAISDVR........................
A0A1U7EQB3_9SACH/20-370             ..................ll--NKENVLASLKDD....PLLTG...AQDEETn............kdPATLDYDAILRKESCLNQQLHDLSSLRSVSGLIMEFKANFELLEFENCYYSLQSLRKKLR......DNAAINKQ.GV....SFQQSVLAHADAMHSQLVHKFYEIITQHFWQV........T.DESIAFEPIV...GLGDDSEDLDYVPFMSFIEQQFY..............SDGFL..DA..........NLWIIGDMRAGP.TQDEVIFELNAIFHDYLNSRMIIEV.IKKFLFSKAKQIVFERGSC.....VKLKLH..........RDGEDKVSDRIANINSVACFLCEGISVR.DIDTFAKKLGPVLATELIQTVKSNPYTVLHSSHSQI.RADVAMANQNLRKLAKK..........--.SNWTY...HGSDVESLLNDNQVQNRLLLDGIFEQYALKIR........................
A0A0C7N2K0_9SACH/24-368             ....................LSDQDSISANIECD....PKLQF...LDVPSA..............nETSTDIQALRAQETLLSDQLVVCRELSVVSDLLEEAKMNLQLCELENCFYSLQNIRRKLT......-VIDFKIL.PM....RFEQDLKLHLDEMHAHLVSRCDDIMHG-FWKI........D.DCGITFVEST...IVGTDRVEFNYSYFRQFLKTCFF..............PNGSF..EP..........TIWFVSSLSMSD.TKEAITTGLSTLFTQYIELEVVQEK.LKSLLFSENVFLELKS---.....ESTLEV..........TTKKCSLDEILCKYTALVLFLLRAVTSD.DQNTILSRLGNTIAVEVLKFFKQNSTVLLSPGSKQ-.KEQLIRLNDDLKLLSDS..........TK.GVWVY...NGTELDALLNDDSVINNLKLDKLLQSQIVKIR........................
Q752C3_ASHGO/45-390                 ....................LGNPMQVLAAIEDD....PSLWL...DSSEKK...............PNHLALQELKQRDVEVTKTLQQHLRLKIVADLLIKYNSEIQCAEFTAAFETLRQCVQKAK......-SADVSAH.GV....RFEQAFNTYLSGLHAVFVRKLQGLLEE-VWHI........H.DDGFSFQQQVsekLDDAREHNFDYDTLVDMFNSCFL..............KDGDI..DE..........RSWFFKNISMPD.VRDDVKQCVNSTYNNYIKLSQVKEN.LKGFLFSDSLRISCS----.....GTRLHV..........DQGCETPAAKVESYVVLADYLLNVLSPV.ASNQILMTLGGAIVTEATKLLKQHSKELLSKEANQ-.KKDLAHFNDTLVKLSSR..........KG.SSWTY...NGNALDKLLNDPETFATLMFEQHVHLHLLKLR........................
G8ZQK5_TORDC/17-366                 ....................LADRNGILHQLEDD....PVLIN...DELREP...............-SKIDTDAILKREMGLSRELREYTALKTVPSLVLEFKTNLHLLEFENSFYSLQTLRKKLR......DFSEILSQ.SY....GLQRSVATYVDNMHLDLVNSLYSILNDGFWKI........G.SDFVSFQEKV...AFGNDRVDIDYVDFMASMVSLYF..............PQGHL..DP..........KSWIISDMILGT.MQETVRAKLDFILKEYVKLSGVTNL.IKSCIFAQSSEALLEDNNKt...lKFRQSS..........KKGDEKFKETLSSFKNVLQFLTETVVSQ.DKKILAERLGPSISTELMKSIKANASIIFRPENTHL.RDESLAINLILKDLSEN..........-S.DIWSY...NGSELERLFSNSDIPTNLQVDKILQDQLTELR........................
A0A1E5RGU1_9ASCO/23-406             ....................LKDQEHIQLEIEND....PKFNElflAKGQENdnsnai..iahetknPTIDKKSDILSKDQEYITQIEVLRSLQLIARLIEEFEKCLAKWSFEDAYVKLQQMCEKHK.....tLWQSFPLQlSL....QLQKSLTSKLDELHLDFLEKLVKVYKF-FFQT........N.EDKNELVLNV...VSEDGNVSL--KDVHTFVVSSLL..............EHKNI..ENvtkenstlfiDTWFIDSIVDSNsVMEHCLSLMNGVAIKYIKLNNIIDRyIKYVLFHNSVCLSITKNSGlcwsvETSTLS..........SNEKVPFERQVENMQNVAALYDFLMVQN.QEYYNFSKLSQTLVKQFENFIKLNVKPLWNKETNF-.KKEIIKIVEKSETLSRSnll...nillDR.SG---...------------NTYNSIIMDKLIREGFVE--lrnlfsdttvlek...........
A0A4C2E9S2_9SACH/12-364             .................lls---KAEILESLGND....PLLVN...EKESKSdk...........qdNFSVDYEGILRKESFLNEELHDLASLRSISGLIMEFKANFELLELENCYYSLQNLRKKLR......DTSSLTKQ.SF....SFQQSVFSHVDIMHLQLVSKLYEIISQWFWQV........N.EDVITFKQVV...EWGSDSETMEYVSFITFVEYQYY..............PDGFL..DP..........NLWMIRHMKVGS.SQDTVIESLTSILRDYLSLNLIVDT.VKRFVLAKNGKITWENLGN....tQKLHFN..........QSGTGTVGERISNILNVVKYLNEGVNSR.DKNTFSKRLGPLLANDLLQSVRSNAYSVLHPSDSPL.KEEVRVVNENLKALSKG..........--.TDWNY...QNGDVENLLSDDQVHKNLLLDGIFENYAIKVR........................
A0A1G4JWI2_9SACH/21-364             ................lgri----EIVKKSIKND....PNFAL...PRLVVD...............DRNADINALLKADVELTEKLHAYKELRIIGGLLKEFYVNLELWELESCFYSLRNIHQKLQ......-KNILAGQ.SR....QFKQSVNDSVDHLHFQLIERVRDALDG-FWKF........G.KDSITFRSSF...TTESGDNEILYNEISECVKSHLF..............EDAVLgsNS..........SCWFVSSIESIA.TKNVVIQELSAISDKYLKHEQTILF.FKKFLFSSDIVLFLE----.....GSCIIS..........ERRTRTIDLTLDSFQNLATFLSGIVSAK.DADLILQSIGNLLVNEIIKFVRQEAAQLLIVSQQ--.RQRLIDINAAMADLSLN..........TA.VHWCY...DRSKLDVLLADEKIIIDLKLDQILHDELLKLR........................
A0A1V2L1Q6_CYBFA/15-195             .deqitrlvavdslktqlsa--------------....-----...-TSHRS...............LDIKELGQLQARDGQIVTEIEQLQELWVITTLKKEVEVNLEMFEFENVFASLQKLTEKIQg....iSLNSASVK.TK....WLERATQLQ-DEVLETFTKTWKQLVSVDEESS........G.AVSVTFHEEV...--EIDDFAIAFESLADVVETFAL..............PQNIF..NL..........AH----------.-------------------------.-------------------.....------..........----------------------------.------------------------------------.-----------------..........--.-----...--------------------------------tidtcfmdtyldd...........
G0WD68_NAUDC/10-396                 ....................LSNKDELISSIKDD....LLLLQ...NKNNITttgndaeddlnvskmDKTPDVNTILTKETQLATELHDLQQLKTISSLIMEFKTNFELFELENCFYSLQSLRKQIGtitinnNNPSFARQ.NY....HFQRSVIVYIDSLHLDLISRIFEIITLKFWNI........T.SESISFNPKLnvqTTDGLDVEIAYDSFISSIKNLYF..............PNDII..DS..........EFWIISNVELND.LHESIRNKLQTIFKDYINLDGVSAM.IKNAIFTNNKQFKYANNKLs...iISSLTS..........MNQTDFLTTTIESFQNIITFLNETLPLQ.DRNILLSKLGNTITTELLKFVKVNISKILNNENSNLmKDQTLKINTELITFAKHftlsssshsgLN.NFKNY...DGQQIIELLNNNRIYYNLLLDNSLYDQIKQMR........................
J8Q396_SACAR/5-358                  ..................sh--NKDEIIRELRKD....PLVIK...SDNQKIn............sgELKLDSSELLRQEATLANELNTLDNLKALSTLIVEVKTNLDLLELENCFYSLQSLRTKMR......KNTAFLKQ.SF....NFQQSVSSYVDTLHLELVNALHKILTTGFWKI........T.ENSIQFTPTV...KWGKNEVDIEYDTFMDFVVRQYF..............PQSSL..DN..........QAWIISDMGNAD.SQEQVRAKLNTILKDYINLTSVVNM.IKCSIFIPGRQVSYEEEKN.....MLVFSQ..........SSLQNNTSAALTSFETVCDFVLDRLSLR.DKKTLSYELGHLFNTEFTKFVKNNASIILDSLDSPL.KKLVSVTNDKLIRLASE..........TGvTNWSY...SGKEIQDLLMNKQLYYNLLLDKILESHIKDLR........................
A0A1E3P269_WICAA/26-203             anlraqvenvggvskalsfd--------------....-----...------...............----ELSKLQQRDYEITQELQQLRELWVISTLLKETEVNLELFEFENVFDSLRNFQKKIK......-SDSLTSS.LI....IVDKLQNEH-DRCYDLAIEKIKQCWNE-LIHV........D.NDSIEFNAEV...EINGNLVQF--ENISDVIKTNNL..............QTKIP..NS..........------------.-------------------------.-------------------.....------..........----------------------------.------------------------------------.-----------------..........--.-----...--------------------------------ntshlidqkllnslteskslnlsd
A0A1S7HMD7_9SACH/12-362             ..................ll--NKDSVLASLKDD....PLLTG...AKDELTn............ndPATLDYDAILRKDSRLSQQLHDLSSLRSVSGLIMEFKANFELLEFENCYYSLQSLRKKLR......DNAAINKQ.GV....SFQQSVLAHTDAMHSQLVHKFYEIITQHFWQV........T.DESIAFEPIV...RLGVDSENLDYVSFMRFIEQQFY..............PDGFL..DA..........NMWIIGDMRVGP.TQDAVISELNAIFHDFLNFRMIIEV.IKKFLFSKAKQIVFERGNC.....VKLSLH..........RGGEDNVSDRIANINNVACFLCEGISVR.DIDTFAKKLGPVLATELIQTIKSNPYTVLPSSHSQI.RADVAMANQNLRQLAKK..........--.SNWTY...HGSDVENLLNDNQVQNSLLLDGIFERYALKIR........................
Q6CUS2_KLULA/12-352                 ....................LSDTSALSQAIEAD....PQFKS...SDSVHP..............kPNSKLLEEVLREDSDLTKDLAKYNQYKILSDLLKEFNTNYELNELENCYYSLQNIHKKFK......-DVNISGE.SF....RFQQSVATYIDCLHLNVLERFKEV-SNMFYTI........S.GNEMMFKKTI...--ELDSVEFNFDEMVELFENNFF..............DHNMI..DQ..........THWFIASTNLET.YKDKEIVLLQEILDDTVKLNPLIKF.FKEFVFDEKCIMVRAE---.....PGKLTL..........ATSEYNSLDQIKSYQTLTTFIENDLSKH.AKESVMIHFGNVLLTELLKIIRANPELLSNDKEQT-.TEIISSIHDSLTKISEE..........--.TEWAY...DGFELNRILKDENIYTTLKFESMMQQRVIQIR........................
A0A376B2R6_9ASCO/21-405             ....................LSDQNSLQLAIKND....KNYNQ...VFGPTVdnt.........psiTSPEDLDRLKNQDSEYIAEIDQLLLLKTINQSLNEFQTNLKLSEFENCYYTLKNLVNQFNk...llN---LAETnSYqikpTLPKSISNKIDSLHLDFLTLLENMYNR-LIAIrd...vdaN.TKVLNINRSI...----GNNELHLKELNEFMVKTLLesqesiatknpiayNGPDS..TL..........KIWFITSITETS.KVEECLKRLDHLITTYLQLSPILNKfVKCFLFSSKIQVELTTTGDe..rlDLKLIE..........SAENLSLQDYLTSFINMVQFVDSLIGWDsKLMAFFEPVSTLFQKELEKFIKLNIKEILKVGNDA-.-EHHNALLLNLQKLLSQee......gkKS.SILTLcgnSKTNLSLLLKDEKVYKQVILDQLIQQKFEELR........................
J7S867_KAZNA/6-376                  ...................a-PEREEVLLSVERD....PIFQG...ENGADVaas.........nytQLTERIREVVAQEAQLGSMLHDLSVLKTFGDLLNEFNTNLAKSLFQDCYRALQTLRQKLN.....tSRDCFVKQ.PL....HFQRSLMNYIDELHLTLIERIYEIISTDFWSV........T.HDSITFHNKI..vCSEGSGGQFEYRQFMELVKKLFFw............dDGEIS..TE..........DTWFLKDMDLNNpSSNIVRNKLSEISKNYLELNEIVVN.LKRGIFDNSIKFEFQAESC.....TLSFTKvknaipnssgSYNKAALASVVESINALADFLMQCIDGN.DLVIILSKLGPLLSNELLNFLRKNATVILRDSDPSI.REGIVLINNRFGVLASK..........SN.GFWNH...NRNDIEHLLNDKQLYINLLVDDAFAKTFKEIR........................
I2GW53_TETBL/22-390                 ....................LNNRDILVASIKND....IESTI...EDSPTQppti.......ethiKAHIDPFVIQQEDTQLSNDLYELNKLKTITSLIMEFKTNYELMEYENCYYSLQNLRKKIH......ENEPILVK.NY....HLKQSLSSYADGLHVQLIEAIHSLVSKGFWKIptvsasdnQ.NVSIEFQKII...HWGNGHIEFEYEFFIDFLRDALF..............PDSKF..DL..........QNWLITELVSTD.LQQIVKDNMDSLFNEYIQFSTLVHV.LKTGIMNRNYSIVLTGEASn...iINLQTK..........LNSKSSIQDYLYSLENIIEYLKNTLLER.DSITIFNQIGNYFFNEIIKLIKSNTYIILEDDGNDIlKSQISKICNTLSFLSKR..........NT.SIWKF...DEDEITHLLNNRQLQSNLLVDKLFETKITTIR........................
A0A1E4RZ31_CYBJN/18-178             ..........vldklvgeit-------------D....VKKLQ...EQLTLK...............VDTQQLGELESKDIELQDELDQLQELWYLMTLQKEIEVNVDLFEFETVFHSLSKLKSKVD......-QMNIKSD.AI....R--SKLMMEGSRLEDLAVNKLLDCWDQ-IVHV........T.GGSVTLNSEI...HVDG--FPISFEAV---------..............-----..--..........------------.-------------------------.-------------------.....------..........----------------------------.------------------------------------.-----------------..........--.-----...--------------------------------vlivehyslpqprfnlpm......
H2AUI4_KAZAF/5-354                  ....................LPDRETLISLVEQN....-LILK...NKNTID...............DPSLEMNKILEEESKLSEELRDLTKLKTISSLLKEVNVNFELLEFENCYYSLKSLRSKLT.....eNNSVFIKQ.TY....RFQRSTALYIDSLHSKLIDSIHEVITTKFWNI........T.SNTIKFNPKI...KIGDDDVQFDYTEFMSFAKSSFF..............TKDTS..SS..........EFWFLATMELGD.YKENVRSKLNDINRNFIEFNNIIGS.IKNLIYDDSVNVTYSTQDN.....ILSFQK..........GESNDYLEKIIEKSQAIVNFLTETFLPN.NLYVIVSEVGSLLSTELFKTAKSNASQLLRDRKNPL.IDLVRSINSSLIKLSNE..........IK.SNWKY...NGSDIDHLLNDEKVYINLLIDKTFDAEIKMLR........................
C5DK93_LACTC/23-365                 ....................LNDQDAILAGIESD....PNLKM...EGSARR...............EEPSDVQAILNQDVQLSKKLGALKELNLVANLIDEFKANFELWELENCYYSLQNLHKRLE......-KVDMSLF.PI....QFQGLLKVHIDSLHVDLLSRIDKVMRQ-FWDI........S.ARSVTFNQKI...AVDRDDVLLEYDSFSLFLKSCFF..............SQDHF..EP..........TSWFVATMNMGD.AKDKVTNLLATAFNEWVRLQTVQEK.LKQFLFSANVCLSLK----.....GCTLGA..........SENPGNLDDTLKSFEALVMFMKDVTTAE.DTAVILAKLGNTLLTEIVKFVKQNSSHLFAPGTNY-.KNSVVSLNTMLTELSHK..........GG.KSWQY...AGRELDNLINDDSVINNLMLDKLLQEQISAIR........................
G8BQ21_TETPH/10-363                 ..................vl--NEQSIKESLLQD....PLLFR...NKSGDSvd..........snsNELLSFESVMNKDTALVAELHDLNSLKQISDLILEFNANWEYIEVENCYYSLLNLRKKLK.....qNDTVLAKQ.NI....RFQQSVITYVESLHLKLIEKVSDLLTEKFWNI........T.SNSVVYNASV...--ELNNVKFEYKPFLEFLSNELIi............eNDNIL..DL..........NNWFIKDMSLGE.LHNMVRNKMKIILNDYLHFELLLNK.LKEALFNSNMKFDYDVNNR.....KLSWEE..........NYHDVKSKDKLESLTNIVNYMNTELSEL.NSK-LIEKLSPLVANEFTKLVKGNISEIVQNENL--.STTVLTLNESINNLKSF.........tQT.ASWYF...DTAVINDLLKSKEVYNNLILDQILESHLEQLR........................
K0KHW4_WICCF/11-177                 ........leslnekihqlv-------------D....PEVLN...SQLNGSk.............tLDFNTISKLQQRDYEITQELQQLREFWIVSTLLKETEVNLDLFEFENVLYSLKNFEKKIK......-SDSFDTK.LI....ILEKLQAEH-DRLYNLTIENIGTSWSK-LIEV........Q.ESSVTFNAEV...--DINGNTVLYESVSDVIKSN--..............-----..--..........------------.-------------------------.-------------------.....------..........----------------------------.------------------------------------.-----------------..........--.-----...--------------------------------dlqlkvpnsnii............
A0A7H9HNE0_9SACH/16-365             ....................LGNRDEIARRLDND....PLLRK...NEDGES...............-LKIDLEAILRREKELSNELHDFTALKTIPGLILEFKTNLQLLELENCFYSLQALRRKLH......ANFSIINR.SF....GLQRSIMTYVDNMHLELVNTLFATLKDGFWKI........N.ADAIEFQSTV...THGDDQVQLQYADLMDSVENLYF..............PSGQL..DQ..........KLWIISDMVLGT.LQETLRDRLNTILNEYVKLSDIVSL.IKSCLFAENKQFMLANDNSk...lIFEDST..........KDGDEKVEETANSFKNLLLFMRETVWLR.DQKILAQKLGSLIATQLLEFIKVNSSVVFRPENAQL.RVIIGEVNQDLVKLSTE..........-T.SSWSY...DGTAINDLFNNDQIPMNLHIDKVFHEQITELR........................
G0V593_NAUCC/12-369                 ....................LGNRDALIQSIEQNletpPLTAT...HDGNSS...............TQELNRGQLMMKEEQLSSQLHDLNNLKILSGLLIEFKTNFELLELENCFYSLQSIRKRINg....nNNSSFLKQ.SF....HFQRSVAVYVDTMHSTLIDKIFEIITTKFWQI........NdTGSIAFHKKI...TYGPEDIDLEYESFIDFVKQQYF..............PQNVL..DS..........QLWIISDMDIND.LQENVRGKLQTILKSYIHLNVVIDR.IKKSIFTKGKMFDYELGKLl...fKDVSNI..........TDNQSLLQETIASFTSLVRFFQDILIED.DCITVLTSLGNVISNELTKLVKQNASVILND-NSPL.KDRIIEVSKSLVKLADR..........TK.NQWHF...NDSEILNILNNEQIYFNLMLDKKFNEALEYMR........................
A7TF57_VANPO/11-362                 ...................v-ADKERLLQLLRND....PLLSL...NDDVEI...............TEKIDLEGLLKLDASLTEELHVLNSLKTIPSLILEFKANMEYLELENCYYSLQNLRKKLK......ENDTLVRQ.NI....RLQQSVATYVDSLHVQLVDKLFDLISNHFWNF........K.EHTISHKDEI...VYGKDKVKFDYETLLEFVNRDIF..............PQNVL..DF..........EHWLIKDMVMGD.LQEIVRERLSTIVKSYILFDSIIHD.VKENIFNDKGIFTYDEDSKk...lSLVDSR..........SKDLDLLTEKLVGFGKLADYLLSCISKR.DVVILSSRIGPSIAKESHKLIKENISSILQEQSTSI.KNLILELNDKLLSLSNA..........TN.GVWNY...SGNETEELLNDKQIYNNLLLDKIFEEQVNRIR........................
A0A1X7R2M1_9SACH/5-355              ..................ii--EENRIITSIAND....PIFAK...DDVDTR...............SSNLDVNHILETESQLSSQLHDLKNLKVLASLIKEFNTNLELLELENCYYSLQNLRKKLK.....eNNEAFIKQ.SF....HFQKSVVTYVDSLHVEFINKLYDIFSQGFWNI........T.DDSIRFRSSI...EWGDENFLLEHDLLLDLVKQLFC..............PGDTL..DL..........HSWIIDDMEFGN.DRDTVRTKIEDLHKNYILLNSLINP.IKDKIFSKNALIKYTKKDD.....TIKFIV..........SESKPSVPMLFDCFQALCDFSLNTIPQS.LLPILLKSIGKVLENELLKCVKNNAGEIIGRDNKDL.KEHASKINDLFSTLSSK..........SQ.GNWSY...HAHTIKDLLQDRQLYINLLVDEIYHRAVRDIR........................
A0A1G4MGQ1_LACFM/21-362             ...................l-EDLDSLAAAIESD....PNFRP...YEKAST...............-QNTNIDELIKKDAELSGQLSVLTSLKVVSAFIDEFKTNYDLWELENCYYSLQNMHKKLE......-TIDLSNL.SL....RFQESLSTYIDSLHADLVDRIKDLLGK-FWSI........D.RHKIQYINNV...RMGEDEIEFEFEGFKVFLETCFY..............SDGHF..DP..........NSWFTSEIRMGD.TRDEVSNALSEIYTEYITYSKIITI.LKESLFSSDVQLVLCE---.....-DVLLF..........QHAKCQTEQVIASFENLAYFLLHISPKS.CSSLILSQLGNTFVNEIVKFVKLRSNEVLTPDSSS-.KLELIKLNQMLVDLSEK..........VN.TSWKY...HETRLTSLLYDEHILNNLLLDKLLRNQVVELR........................
DSL1_YEAST/5-360                    ...................f-PNKGEIIRELLKD....PLILK...NDSKRSn............gsELELDSSDLLQREAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMR......NNAAYLKQ.SF....NFQQSISTYVDTLHLELVSTLYKILTNGFWKI........T.ENSIQFTPTV...EWGKDKVHIEYDTFMDFVAQQYF..............PKGSL..DN..........QAWFILDMTSAD.SQEQVRAKLNTIMKEYMNLSRIVSM.IKNSIFISGKEISYENEKNi...lVFSKSS..........SHGQHCVSTVLTSFEAVCDFMLDGLAFR.DRKTLSYELGPLFNTEFTKFVKNNASIILESLDSPL.KNLVSVINNKLTRLVAK.........sEV.TNWTH...SGKEIQDLLMNKQLYYNLLLDKVLESHISEIR........................
#=GC seq_cons                       ......................sp-plltplcsD....Phhht...pcssps...............ppph-hspllp+-spLop-LcsLppL+slusLlhEFcsNh-LhEhENCaYSLQsL+KKlc......pssshspp.uh....pFQpSlssalDsLHlpLlp+lh-llsp.FWpI........s.scSIsFpppl...phss-pspl-Ycshh-hlcspaa..............spshl..-s..........phWhIsshthss.hp-pVpspLssIhppYlphs.llph.lKphlFspshphthpptt......hhhh.p..........ppsptphpptlpuapslspFlppsls.p.ct.hlhpcLGshlssElhKhlKpNsp.llpspss...+pplhtlNppLtpLupp...........t.s.Wsa...sssclppLLpscplh.sLhlDplhppplhclR........................
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