#=GF ID   E2R135
#=GF AC   PF11570.12
#=GF DE   Coiled-coil receptor-binding R-domain of colicin E2
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_2ysu
#=GF GA   21.40 21.40;
#=GF TC   21.40 21.90;
#=GF NC   21.30 21.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   17548346
#=GF RT   Structure of the complex of the colicin E2 R-domain and its BtuB
#=GF RT   receptor. The outer membrane colicin translocon. 
#=GF RA   Sharma O, Yamashita E, Zhalnina MV, Zakharov SD, Datsenko KA,
#=GF RA   Wanner BL, Cramer WA; 
#=GF RL   J Biol Chem. 2007;282:23163-23170.
#=GF DR   INTERPRO; IPR024566;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   E2 is a DNase which utilises the outer membrane receptor BtuB to
#=GF CC   bind to and enter the cell. This family of proteins is E2R135
#=GF CC   (residues 321-443) which is the part of E2 which is responsible
#=GF CC   for binding to BtuB in a coiled coil formation [1].
#=GF SQ   11
#=GS A7T1P2_NEMVE/1-63         AC A7T1P2.1
#=GS A0A3Q1G9J1_9TELE/27-127   AC A0A3Q1G9J1.1
#=GS Q814D9_BACCR/26-122       AC Q814D9.1
#=GS A8ARS8_CITK8/226-361      AC A8ARS8.1
#=GS A0A1W2FEM3_9HYPH/25-90    AC A0A1W2FEM3.1
#=GS A0A378QE36_KLEPR/322-457  AC A0A378QE36.1
#=GS A0A8C1DVG7_CYPCA/504-647  AC A0A8C1DVG7.1
#=GS A0A0Q7YZF5_9SPHN/2-117    AC A0A0Q7YZF5.1
#=GS J2X096_KLEPN/322-457      AC J2X096.1
#=GS A0A8J3DT09_9HYPH/322-457  AC A0A8J3DT09.1
#=GS A0A7X6K809_9MICC/322-457  AC A0A7X6K809.1
A7T1P2_NEMVE/1-63                    ................................ee---------------------------------..-----------------..--------------...-.---------MQEKLRQLERDIQNSENKLKAA....QDEKV.......ELEEELG..RARDGAEKSRDERKITESK---------kelkgrge......
A0A3Q1G9J1_9TELE/27-127              ......................eqetdtflltst---------------------------------..-------------DEDS..KHSEGEANSDQFLS...Y.NLPAN-ESPHQEGSKYVDSELS-RNAVVKPK....KSHNR.......EISHSNN..VDKSSLSESHNDTDTGRK----------svkfdvcentf...
Q814D9_BACCR/26-122                  .........................vgkkrlsrv--------------AKMIAPDLNVPSLGD-IASdvTEKVVDGAKESVKETAK..DTREAQKKADDKVAdvlY.KPPFKVSNKTKETLDRLHKNSTNS-------....-----.......-------..----------------------------kkvsaykdr.....
A8ARS8_CITK8/226-361                 ..................................HPEEGLKREYDKAKAELDAEDKNIATLNSRIAS..TEKAIPGARAAVQEADK..KVKEAEANKDDFVT...Y.NPPHEYGSGWQDQVRYLDKDIQNQNEKLKAA....QTSLN.......EMNESLS..RDKAALSGAMESRKQKEKKAKDAENKLN..............
A0A1W2FEM3_9HYPH/25-90               .................tllgaaasglalasapg---------------------------------..----VMAAPLAAKETDY..KVTDKITSKEDATT...Y.NNFYEFGTGKDDPVRYS--------------....-----.......-------..----------------------------gdfk..........
A0A378QE36_KLEPR/322-457             ..................................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADK..KVKEAEANKDDFVT...Y.NPPHEYGSGWQDQVRYLDKDIQNQNAKLKAA....QASLN.......AMNESLS..RDKAALPGAMESRKQKEKKAKDAENKLN..............
A0A8C1DVG7_CYPCA/504-647             hpeyptvlqsldienpvvanclidmrgietilli---------------------------------..--KNAKDARRAMQSVNRprNCMEAFTREGDQVY...Y.N---RYYSSEQDRVRYLSKDIEEENRHLQSAlhaqQTHLDrfqqdmqQVSEEER..RNKTLLCRAHEERKMAQ-----------eccrklqael....
A0A0Q7YZF5_9SPHN/2-117               .................................f-------------------DNKNVATLNSLIAT..TLDSVDGYRKAADEAN-..----AAQFKDQFLS...RaNERQAIVTNFQAKVRELGGNPEDDGTILASA....HRAFL.......GLRDKLTgeRDDAAVVAEVERGE--------------dhikakfesalkde
J2X096_KLEPN/322-457                 ..................................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADK..KVKEAEANKDDFVT...Y.NPPHEYGSGWQDQVRYLDKDIQNQNAKLKAA....QASLN.......AMNESLS..RDKAALPGAMESRKQKEKKAKDAENKLN..............
A0A8J3DT09_9HYPH/322-457             ..................................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADK..KVKEAEANKDDFVT...Y.NPPHEYGSGWQDQVRYLDKDIQNQNEKLKAA....QASLN.......AMNESLS..RDKAALTGAMESRKQKEKKAKDAENKLN..............
A0A7X6K809_9MICC/322-457             ..................................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADK..KVKEAEANKDDFVT...Y.NPPHEYGSGWQDQVRYLDKDIQNQNEKLKAA....QASLN.......AMNESLS..RDKAALTGAMESRKQKEKKAKDAENKLN..............
#=GC seq_cons                        ......................................................shNlsoLss.IAo..T.KslsGARtAspEsD+..KspEApssKDDFVo...Y.NsPacauSuaQDpVRYL-KDIpNpNt+LKuA....Qsphs.......thsEpLs..RDKuuLstuhEpRK.tcp........................
//