#=GF ID EF-hand_12
#=GF AC PF17901.5
#=GF DE EF-hand fold domain
#=GF PI EF_hand_12;
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF01569
#=GF GA 25.00 25.00;
#=GF TC 27.70 65.70;
#=GF NC 23.20 20.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0220
#=GF RN [1]
#=GF RM 15053873
#=GF RT Structure of an activated Dictyostelium STAT in its DNA-unbound
#=GF RT form.
#=GF RA Soler-Lopez M, Petosa C, Fukuzawa M, Ravelli R, Williams JG,
#=GF RA Muller CW;
#=GF RL Mol Cell. 2004;13:791-804.
#=GF DR INTERPRO; IPR041604;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in Dd-STATa, a STAT protein (Signal
#=GF CC transducer and activator of transcription A) which
#=GF CC transcriptionally regulates cellular differentiation in
#=GF CC Dictyostelium discoideum. The EF-hand domains predicted to
#=GF CC contain several basic residues that lie close to the DNA
#=GF CC backbone [1].
#=GF SQ 31
#=GS F1A659_DICPU/505-597 AC F1A659.1
#=GS D3BJ33_POLPP/584-676 AC D3BJ33.1
#=GS A0A8J4PSY0_9MYCE/554-646 AC A0A8J4PSY0.1
#=GS A0A151ZGP8_TIELA/237-329 AC A0A151ZGP8.1
#=GS STATA_DICDI/484-576 AC O00910.1
#=GS A0A152A131_TIELA/437-529 AC A0A152A131.1
#=GS L8GWB9_ACACA/342-434 AC L8GWB9.1
#=GS A0A8J4PQE6_9MYCE/344-436 AC A0A8J4PQE6.1
#=GS A0A8J4PWR4_9MYCE/590-681 AC A0A8J4PWR4.1
#=GS D3B679_POLPP/526-618 AC D3B679.1
#=GS STATC_DICDI/703-795 AC Q54BD4.1
#=GS STATB_DICDI/898-990 AC Q70GP4.1
#=GS A0A8J4Q6R9_9MYCE/815-907 AC A0A8J4Q6R9.1
#=GS F0ZVN4_DICPU/259-351 AC F0ZVN4.1
#=GS D3B897_POLPP/442-534 AC D3B897.1
#=GS A0A2P6NCB6_9EUKA/460-554 AC A0A2P6NCB6.1
#=GS L8GXQ7_ACACA/584-659 AC L8GXQ7.1
#=GS F4Q5C0_CAVFA/555-647 AC F4Q5C0.1
#=GS F0Z7T3_DICPU/562-653 AC F0Z7T3.1
#=GS F4PP04_CAVFA/908-1000 AC F4PP04.1
#=GS L8GN02_ACACA/459-548 AC L8GN02.1
#=GS F4Q0R8_CAVFA/437-529 AC F4Q0R8.1
#=GS F0ZYW4_DICPU/38-123 AC F0ZYW4.1
#=GS A0A151ZBU7_TIELA/465-557 AC A0A151ZBU7.1
#=GS A0A2P6MTS6_9EUKA/395-488 AC A0A2P6MTS6.1
#=GS A0A152A2U6_TIELA/589-680 AC A0A152A2U6.1
#=GS A0A2P6NV19_9EUKA/424-516 AC A0A2P6NV19.1
#=GS L8HD01_ACACA/528-620 AC L8HD01.1
#=GS A0A2P6N6K9_9EUKA/380-474 AC A0A2P6N6K9.1
#=GS F4PGA4_CAVFA/594-686 AC F4PGA4.1
#=GS Q86I20_DICDI/594-685 AC Q86I20.1
F1A659_DICPU/505-597 NECQYEESDGTLLKKDSF..G.N.NNEIPWASYANKLQRHFLRATRQDFMKPTRYLSRHELMYIHHQFFGSKPMIPQSSFD.SFWVWFGKGLQKLRYQ........
D3BJ33_POLPP/584-676 NESQWSEAAGKLLVGEIF..E.D.RSEVPWELFANILHSHVFTTTGQIPNEPKRKLHTWEWDYIQQNHFGSKASLTKTECK.EFWAKFGPILQTIHFK........
A0A8J4PSY0_9MYCE/554-646 NECQYEESDGTLLKKDSF..G.N.NTDIPWASYANKLQRHFLRATRQDFMKPTRYLSRHELLYIHQHFFGGKPAISQSSFD.AFWIWFGKGLQKLRYQ........
A0A151ZGP8_TIELA/237-329 NDCQWEGSEGTLLKKESF..S.E.KFEITWPHFVNILQKHFLKATKQSPIQPTRPLSNYDFVYLNLTFFQHKTSVSHKDFD.QFWTWFGKCIQTLRYK........
STATA_DICDI/484-576 NECQWEGSAGVLLKKDAF..D.G.QLEITWAQFINTLQRHFLIATKQDPVRPKRPLSSYDLKYIQTHFFGNRSIIHQQDFD.KFWVWFGKSMQTLRYQ........
A0A152A131_TIELA/437-529 NECQWEGSAGVLLKKDAF..D.G.QLEISWPQFVNTLQRHFLIATKQDPVRPKRPLSAFDFKYIQTHFFGNRPIIHQQDFD.KFWSWFGKSMQTLRYQ........
L8GWB9_ACACA/342-434 NESQWCDAAGKLLLFEAF..G.G.QTEIPWQHLANVTHTHFLKATRQDPGRPQRRLNHGEFQYIHYKFFGGQLNVTQQQAG.RFWSWFGQVVQTLRFK........
A0A8J4PQE6_9MYCE/344-436 NECQWEGSAGVLLKKDAF..D.G.QLEITWPQFINTLQRHFLIATKQDPVRPKRPLSAFDFKYIQTHFFGNRTIIHQQDFD.KFWSWFGKSMQTLRYQ........
A0A8J4PWR4_9MYCE/590-681 NESQWAEAAGKLLTCDAF..M.D.KEEITWEYFANILHSHILTGTNQTG-EIKRKLHSWEFEYIQKNYFNSKTTVSKLEST.TFWAKFGPILQTVHFK........
D3B679_POLPP/526-618 NECQYEESDGTLLKKDSF..G.N.NAEIAWASYANKLQRHFLRATRQDSIKPTRYLSRHELIYLHQQFFGGRATITQAMFD.TFWNWFGKGLQKLRYQ........
STATC_DICDI/703-795 NECQYEESDGTLLKKDSF..G.N.NNEIPWASYANKLQRHFLRATRQDFMKPTRYLSRHELMYIHHQFFGSKPMIPQSSFD.SFWIWFGKGLQKLRYQ........
STATB_DICDI/898-990 NDCQWEGSEGTLLKKETF..N.E.KFEISWPHFVNILQKHFLKATKQSPIQPTRPLSMYDFTYLSNTFFGGKPFVSHKDFD.SFWSWFGKSIQTLRYK........
A0A8J4Q6R9_9MYCE/815-907 NDCQWEGSEGTLLKKESF..N.E.KFEITWPHFVNILQKHFLKATKQSPIQPTRPLSHYDFQYLNNTYFKNKTYVSHKDFD.SFWSWFGKSIQTLRYK........
F0ZVN4_DICPU/259-351 NECQWEGSAGVLLKKDAF..D.G.QLEITWAQFINTLQRHFLIATKQDPVRPKRPLSSFDLKYIQTHFFGNRSIIHQQDFD.KFWVWFGKSMQTLRYQ........
D3B897_POLPP/442-534 NECQWEGSAGVLLKKDAF..D.G.QLEISWAQFINTLQRHFLIATKQDQVRPKRPLSQFDFKYIQQHFFANRSIIHQQDFD.RFWNWFGKSMQTLRYQ........
A0A2P6NCB6_9EUKA/460-554 NESQWPEAAYRLIDKDMFpsS.N.SRSIPWPFFCNVLQRHLLTATQQPIDNLRRVFGDADFSYLSERFFGRSTKALSEQVK.TCWDWLGHVICTIKFK........
L8GXQ7_ACACA/584-659 NHGQRSTTEGKLLKKHTF..A.N.RSEIPWPAFANAMQIHYIRATKQDPKKPVRPLSNKDIEYLHLTKFNGKM--------.----------------ryvpils.
F4Q5C0_CAVFA/555-647 NECQYEESDGTLLKKDSF..G.N.NAEIPWASYANKLQRHFLRATRQDSIKPTRYLSRHELMYLHQQFFGGRSMVSQSMFD.AFWNWFGKGLQKLRYQ........
F0Z7T3_DICPU/562-653 NESQWAEAAGKLLIADAF..N.S.KDEIPWELFANILHSHILTATHQSS-EIKRKLHSWEFEYIQKFYFDGKTSISKSECK.SFWDKFGPILQAIHFK........
F4PP04_CAVFA/908-1000 NDCQWEGSEGTLLKKESF..N.E.KFEITWPNFVNILQKHFLKATKQSPIQPTRPLSNYDFLYLNATFFGSRLIVHHKEFD.HFWSWFGKSLQTLRYK........
L8GN02_ACACA/459-548 NECQWEESEGILLKKGRL..W.R.---AGRGDFANVLQRHFLRATRQDLIRPTRQLSDLDFEYLNQTFFEGVQVIGQKSYD.AFWEWFGKAVQKLRYQ........
F4Q0R8_CAVFA/437-529 NECQWEGSAGVLLKKDAF..D.G.QLEISWPQFINTLQRHFLIATKQDPVRPKRPLSQFDFKYIQTHFFGNRSIIHQQDFD.RFWVWFGKSMQTLRYQ........
F0ZYW4_DICPU/38-123 NESQWAEAAGKLLIADAF..N.S.KDEIPWELFANILQSHILTATHQSS-EIKRKLHSWEFEYIQKFYFDGKASISKSKSI.HF--------------krhieplw
A0A151ZBU7_TIELA/465-557 NECQYEESDGTLLKKDSF..G.N.NNEIPWASYANKLQRHFLRATRQDFMKPTRYLSRHELVYIHHQFFGGKPLISQAAFD.SFWVWFGKGLQKLRYQ........
A0A2P6MTS6_9EUKA/395-488 NECQFEESDGLLLRAESF..Q.SsDTQVPWALFGNLLQRHFLRATRQDPVKPQRFLSRSELQYISAKFFGGNSNITIKMFD.DFWAWFGKGLQKLRYQ........
A0A152A2U6_TIELA/589-680 NESQWATAAGKLLAADAF..G.D.KEEISWELFANILHNHLLKVTGQEN-TIQRKLHSWEFDYIQKNYFNNKKTVSKSECK.TFWDKFGPILQSIHFK........
A0A2P6NV19_9EUKA/424-516 NENQWHEAEGILLKKTAF..G.N.LNEITWFRFSNWLQRRYLGATKQNSQFPVRPLSTYDFQYIHALKFDNKPIITQKHFD.NFWHWFGPLIHKIRYQ........
L8HD01_ACACA/528-620 NECQWAEAEGTLIKKEAF..G.G.HLEIPWARFANVFHMHFIRATRQDVNKPARAFHAGDFEYLHDKFFGNKQMVSYKDFD.QFWSWFGKGLHILRYQ........
A0A2P6N6K9_9EUKA/380-474 NECQWPKCAGILLKKTIY..NaS.QLQVPWARFANCTQYHFIKSTRQEMTTPTRPLSSTDLQWLHTKFYNGVQLISSRDFEsNFWDWYGKVLKMIRY-t.......
F4PGA4_CAVFA/594-686 NESQWAEAAGKLLIGEAF..E.D.KDEISWELFANMLLGTLFVATSQTPYDPKRKLHTWEFDYIQQTHFAMKPRVTRQEVK.EFWVKFGPILQTIHFK........
Q86I20_DICDI/594-685 NESQWAEAAGKLLIADAF..A.H.RDEITWEMFANVLHSHILTATHQTS-EIKRKLHSWEFEYIQKNYFDGKVTVSKSECK.TFWDRFGPILQTIHFK........
#=GC seq_cons NECQWccosGpLLKK-uF..s.s.p.EIsWspFuNhLQ+HFLpAT+Q-shcPpR.LSsa-FpYIpppFFus+shloppcFD.pFWsWFGKslQpLRYp........
//
