#=GF ID   ESAG1
#=GF AC   PF03238.17
#=GF DE   ESAG protein
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_3037 (release 6.5)
#=GF GA   27.00 27.00;
#=GF TC   350.60 349.70;
#=GF NC   23.70 22.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR004922;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Expression-site-associated gene (ESAG) proteins are thought  to
#=GF CC   be involved in VSG activation. This family includes ESAG 117A
#=GF CC   Swiss:P04477 as well as ESAG IM Swiss: Q26705.
#=GF SQ   13
#=GS Q38G40_TRYB2/98-326   AC Q38G40.1
#=GS Q4GY89_TRYB2/98-322   AC Q4GY89.1
#=GS Q4GY93_TRYB2/98-327   AC Q4GY93.1
#=GS Q38CM4_TRYB2/96-322   AC Q38CM4.1
#=GS Q580E8_TRYB2/98-330   AC Q580E8.1
#=GS Q582W5_TRYB2/95-323   AC Q582W5.1
#=GS Q4GY69_TRYB2/98-326   AC Q4GY69.1
#=GS Q57TR1_TRYB2/99-329   AC Q57TR1.1
#=GS Q57X43_TRYB2/97-323   AC Q57X43.1
#=GS Q380X2_TRYB2/101-333  AC Q380X2.1
#=GS Q4GY61_TRYB2/96-322   AC Q4GY61.1
#=GS Q4GY57_TRYB2/99-327   AC Q4GY57.1
#=GS Q57VG5_TRYB2/98-323   AC Q57VG5.1
Q38G40_TRYB2/98-326              .MGDQRKKMEKLISYGNEMGDLVAKVGGLFSEVNESVRAVRKYLPDALTTANKYYASIAEITRTAW..DDVKAVEAGGT..AKCEERTFQRVKGLLTPCADQTCPLAKTVNESTLKTYKDGCLAVTVQN..GSVRECFNLPRDNLYRSGAVKNSNDALEWKEVRDr.gASFQLKVKVQEIFGPLITPFAAGQPPSMLLGMVSNITSLHSQFNKVHNNFTSLLFDIDVAGNVTTANSS......
Q4GY89_TRYB2/98-322              .MVEENNRLEKLISHGNAMGDLVAKAGGLFAEVNESVRAVRKEIPGALIKVNKYYTAIAEITRTVW..DDVKAVESGK-..HECKDQEFRGVKEFDVTCGDNACLLAHGVSEGALKHYKNGLLEINVMS..GSVSKCLNLPRNNLYLNGAINSSHGLLKWRQHSA...EMFQLELRVKNIFNPLVASFAAGQSSSVLAEMMANITSLYSRFNEVHRSFTSLLVNPNLTDT-------gdgids
Q4GY93_TRYB2/98-327              .MVKENNRLEKLISHGNAMGDLVAKAGGLFAEVNESVRAVRKEIPGALIKVNKYYTAIAEITRTVW..DDVKAVESGK-..HECKDQEFRGVKEFDVTCGDNACLLAHGVSEGALKHYKNGLLEINVMTksGGVSKCLNLPRNNLYKSGAVNNSNKVLDWRDDADt.vTHFLLKLKIRDIFSTLIAPFAAGQPPSALLDMMANITSLYSRFNEVHRSFTSLLFDTNSIDNVKSTNST......
Q38CM4_TRYB2/96-322              .MVGESEKLEKLISYGNTMGDLVAKVGGLFAEVNESVRTVRKEIPDALIKANKYYTSIAEIVRTVW..DDLKAIPTSID..PKCENGEFDGVKEFEVKCGDSSCPLRNGVSEDALKHYKRGRIEVNVLN..GSVSRCLNLQRKNLYKNGAEKHSSEVLKWPQDDA...TFFQLKLEVQSMFGPLIVSFAAGRTTSALLEMVENITSLRSRFKEIHSDFTSLLLNPNSTDNVNSTDST......
Q580E8_TRYB2/98-330              .MGGKHDKLEKLISYGNTMGDLVAKVGGLFADVNESVRVVRELLPTALMEANRYYTASAEITRTVW..DDVKAVEGSDEeaAKCKGENI-GVTEFPTTCGNHTCPLRDNVSDDTLQKYKDGCLEINVLKtpGYVSECLNRPRNKLYMDGAVNNLSDTIKWRGESRdgaIFFQLTVQVQNVFGPLIGPFSAGQPPPVLLEVMSNITSLHSHFNKVHNNFTSLLFDIDVAGNVTTANSS......
Q582W5_TRYB2/95-323              .MVEENDKLENLISYGNAMGDLVAKAGGLFAEVNESVRAVRNAIPGALITSNKYYTAIAEIARTVW..DDVKAVSNDEG..PECKKGALKGVRGFPVVCVDQTCPLLTGVNEITLQKYRGGCLQIDVLTgsGSVSKCLNLPRDNLYKGGAVKNSTGLINWRENGP...AFFQLQIYVEEIFDPLIEPFTSGKAPPELLDMMANITLLQSYFNDIHRNFTSLQFSTNNIDNMKSTNFT......
Q4GY69_TRYB2/98-326              .MEGKHDKLKKLISYGNAMGDLVAKAGGLFAEVNESVRAVRKEIPGALIKVNKYYTAIAVITRTVW..DDVEALERDSD..PNCHGEKIKNVGEFQVTCGEHFCPLKEGVNESTLQKYKDGCLEINVQDksGQISECLNLPRNSLYKNGAVKYSSDGTNWYGNGN...TYFQLKLHVHSMLSPLTIPLGAGQPPSAPLDMMASITSLYSRFNEIHKNFTSLLLNTNFTGIVNSSNS-d.....
Q57TR1_TRYB2/99-329              .MGEQNDKLEKLISYGNEMGDLVAKVGGLFAEVNESVREVRNELPNTLIKANKYYTAIAVITKTVW..NDVKAVGLDSD.mAKCSRQEFSAVENFEASCGDQTCPLENSVTESSLQKYKDGCLTITILN..GSVSECLNRLRDNLYRSGAVQSSRKILEWRGEDRhgaFYFQLTLEIQQIFSTLITPFAAGKPPFALLDMMANITSLNSHFNWVHGNFTSLLLDIGVAGNVSNTNST......
Q57X43_TRYB2/97-323              .MEGKHDKLEKLISYGSAMGDLVAKVGGLFVGVNESVRAVRNAVPDALITANKYYTAAAEVERTVW..DDVKGMEAPRM.sAECSDPVFTNVAGYKVICPDYVCPFNHGVTAAAFRKYKNECLEITVYY..PNKCRAQGLPRGKLYGNGIVKNLTTLLEWRDDHS...-YFQLTLKIRQMLDPLIVPFASGFPPSVLVGTLSNITSLYSHFNEVYSNFTSLLLGTNTPENVNRTNF-p.....
Q380X2_TRYB2/101-333             .MEGKHDKLEKLISYGNEMGDLVAKVGGLFADVNESVRAMREVLPSTLITANKYYTAISEIVRTVW..DDVKAVKSDDEevLQCRNGKIISTGEFSVKCSAHTCPLGVNVTESTLKKYKDGCLEINVMTesGQVSKCFNLPRNNLYISGARINSSGVLEWSQNDS...AFFRLIVKVQDIFAPLIAPFSAGKPPSVLLTKMTNITSLYSHFNKVHNNFTSLLRDTNITVNADNTNT-nst...
Q4GY61_TRYB2/96-322              i-SKQNDKLEKLISYGNEMGDLVANVGGLFSEVNESVRAVREVLPSALIRANKYYTAIAEIVRTVW..DDVNRPLKQDE..AKCGNQNFGSVGEPKNECVYRTCPLGDGVSEDTLQHYKKGGIEINVQT..GSVSECFNRPRDNLYRNGAEKHSSDVLKWLEGET...TRLQLTVEVQKIFGPLIVPFAAGQSPSALRAMMSNITFLYSHFKEVHSNFTLMLHDTNITDNLNSTHST......
Q4GY57_TRYB2/99-327              .MESEHDKLEKLITYGNEMGDFVAKAGGLFAEVNESVREVRKVLPSALMEANKYYAAIAEITRTLW..DDAKAVKSDDEevLQCRNGKIISTGEFAVKCSAHTCPLEANVTESNLKMYKDGCLEINVMG..GSVSKCFNLPRNNLYISGARINSSGVLEWFENGA...SFFRLIVKVQDIFAPLIAPFAAGKPPSVLLTKMTNITSLYSQFNKVHNNFTSLLLENNITGNVNKTRSS......
Q57VG5_TRYB2/98-323              .MEGEHDKLEKLISYGNQMGDLAAKAGGLFVEVNESVRAVRKEIRDALIQANKYYTAVAEIAGTVWafDGQKVVEGD--..HKCDLEASKKTVEFQSKCSAHTCPLRNGVNKSTLQQYKNGCLEISVMH.sHIVDFCHQSPRNVLYVSGAVKDSGNALKWKPGHA...--FFLTIEVKGIFSSLIASFTAGHPPPVLLAMVSNMTLLYSLFSETYSNFTSLLLGTSITDNLNSTDST......
#=GC seq_cons                    .MsscpDKLEKLISYGNpMGDLVAKsGGLFAEVNESVRAVRctlPsALIcANKYYTAIAEIsRTVW..DDVKAVcuscp..scCcspphpuVtEFpVpCu-pTCPLtsGVoEuoLp+YKcGCLEINVhs..GuVScChNLPRsNLYtsGAVpsSoslLcW+psss...saFQLplcVpsIFuPLIsPFAAGpPPSsLLsMMuNITSLYS+FN-VHsNFTSLLhssNlssNVsoTNSo......
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