#=GF ID   EspF
#=GF AC   PF04806.16
#=GF DE   EspF protein repeat
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_3518 (release 7.6)
#=GF GA   20.20 20.20;
#=GF TC   20.50 20.80;
#=GF NC   19.70 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Repeat
#=GF RN   [1]
#=GF RM   11298644
#=GF RT   Role of EspF in host cell death induced by enteropathogenic
#=GF RT   Escherichia coli. 
#=GF RA   Crane JK, McNamara BP, Donnenberg MS; 
#=GF RL   Cell Microbiol 2001;3:197-211.
#=GF DR   INTERPRO; IPR006891;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   The enteropathogenic Escherichia coli EspF secreted protein
#=GF CC   induces host cell apoptosis. Its proline-rich structure suggests
#=GF CC   that it may act by binding to SH3 domains or EVH1 domains of
#=GF CC   host cell signalling proteins [1]. 
#=GF SQ   11
#=GS ESFU2_ECO57/143-189       AC P0DJ88.1
#=GS ESFU2_ECO57/284-330       AC P0DJ88.1
#=GS ESFU2_ECO57/71-95         AC P0DJ88.1
#=GS ESFU2_ECO57/96-142        AC P0DJ88.1
#=GS Q7DB85_ECO57/67-108       AC Q7DB85.1
#=GS ESFU2_ECO57/237-283       AC P0DJ88.1
#=GS A0A7G5C116_9BACL/13-38    AC A0A7G5C116.1
#=GS A0A257KH50_9BURK/1-37     AC A0A257KH50.1
#=GS ESFU2_ECO57/190-236       AC P0DJ88.1
#=GS A0A653FVW6_9CAUD/1-41     AC A0A653FVW6.1
#=GS A0A072PGS0_9EURO/733-766  AC A0A072PGS0.1
ESFU2_ECO57/143-189                  ........IQPARNMAEHIPPAPNWPAPPLPVQNE...QSRPLPDVAQRLVQHLAEHG.....
ESFU2_ECO57/284-330                  ........IQPARNMAEHIPPAPNWPAPTPPVQNE...QSRPLPDVAQRLMQHLAEHG.....
ESFU2_ECO57/71-95                    taesslhq---------------------------...---QLPNVRQRLIQHLAEHG.....
ESFU2_ECO57/96-142                   ........IKPARSMAEHIPPAPNWPAPPPPVQNE...QSRPLPDVAQRLVQHLAEHG.....
Q7DB85_ECO57/67-108                  ...qvtsf-------------TPSRPAPPPPTSGQasgASRPLPPIAQALKEHLAA--ye...
ESFU2_ECO57/237-283                  ........IQPARNMAEHIPPAPNWPAPTPPVQNE...QSRPLPDVAQRLMQHLAEHG.....
A0A7G5C116_9BACL/13-38               .....ecv-----EMAEHRIPAPEWPFPTFP----...--------------------hnlas
A0A257KH50_9BURK/1-37                ....mmpl----------TPTAPCWRTTLPPVQSE...--RPVPDVS-GLGEHLA---lc...
ESFU2_ECO57/190-236                  ........IQPARSMAEHIPPAPNWPAPPPPVQNE...QSRPLPDVAQRLMQHLAEHG.....
A0A653FVW6_9CAUD/1-41                ........------MAEHIPPAPNWPAPTPPVQNE...QSRPLPDVAQRLVQHLAEHG.....
A0A072PGS0_9EURO/733-766             .......f--PSRSMQQHAPAAPAVASPEPPVQQD...FARP----------------gvvf.
#=GC seq_cons                        .............pMAEHhPPAPsWPAPsPPVQsE...tSRPLPDVAQRLhQHLAEHG.....
//