#=GF ID EssA
#=GF AC PF10661.13
#=GF DE WXG100 protein secretion system (Wss), protein EssA
#=GF AU FIGfams;
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Coggill P;0000-0001-5731-1588
#=GF AU Desvaux M;0000-0003-2986-6417
#=GF SE FIG043089 (Release 2.0)
#=GF GA 24.10 24.10;
#=GF TC 24.20 24.10;
#=GF NC 24.00 23.90;
#=GF BM hmmbuild --aminoHMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 16911044
#=GF RT The protein secretion systems in Listeria: inside out bacterial
#=GF RT virulence.
#=GF RA Desvaux M, Hebraud M;
#=GF RL FEMS Microbiol Rev. 2006;30:774-805.
#=GF RN [2]
#=GF RM 15657139
#=GF RT EsxA and EsxB are secreted by an ESAT-6-like system that is
#=GF RT required for the pathogenesis of Staphylococcus aureus
#=GF RT infections.
#=GF RA Burts ML, Williams WA, DeBord K, Missiakas DM;
#=GF RL Proc Natl Acad Sci U S A. 2005;102:1169-1174.
#=GF RN [3]
#=GF RM 19674902
#=GF RT Outer membrane translocation: numerical protein secretion
#=GF RT nomenclature in question in mycobacteria.
#=GF RA Desvaux M, Hebraud M, Talon R, Henderson IR;
#=GF RL Trends Microbiol. 2009;17:338-340.
#=GF RN [4]
#=GF RM 20852931
#=GF RT New insights into the distribution of WXG100 protein secretion
#=GF RT systems.
#=GF RA Sutcliffe IC;
#=GF RL Antonie Van Leeuwenhoek. 2011;99:127-131.
#=GF RN [5]
#=GF RM 19299134
#=GF RT Secretion and subcellular localizations of bacterial proteins: a
#=GF RT semantic awareness issue.
#=GF RA Desvaux M, Hebraud M, Talon R, Henderson IR;
#=GF RL Trends Microbiol. 2009;17:139-145.
#=GF DR INTERPRO; IPR034026;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC The WXG100 protein secretion system (Wss) is responsible for the
#=GF CC secretion of WXG100 proteins (Pfam:PF06013) such as ESAT-6 and
#=GF CC CFP-10 in Mycobacterium tuberculosis or EsxA and EsxB in
#=GF CC Staphylococcus aureus. In S. aureus, the Wss seems to be encoded
#=GF CC by a locus of eight CDS, called ess (eSAT-6 secretion system).
#=GF CC This locus encodes, amongst several other proteins, EssA, a
#=GF CC protein predicted to possess one transmembrane domain. Due to
#=GF CC its predicted membrane location and its absolute requirement for
#=GF CC WXG100 protein secretion, it has been speculated that EssA could
#=GF CC form a secretion apparatus in conjunction with the polytopic
#=GF CC membrane protein EsaA, YukC (Pfam:PF10140) and YukAB, which is a
#=GF CC membrane-bound ATPase containing Ftsk/SpoIIIE domains
#=GF CC (Pfam:PF01580) called EssC in S. aureus and Snm1/Snm2 in
#=GF CC Mycobacterium tuberculosis. Proteins homologous to EssA, YukC,
#=GF CC EsaA and YukD seem absent from mycobacteria [1].
#=GF SQ 119
#=GS A0A1S2R6L3_9BACI/5-151 AC A0A1S2R6L3.1
#=GS A0A135W0U0_9BACL/5-159 AC A0A135W0U0.1
#=GS A8FA33_BACP2/607-690 AC A8FA33.2
#=GS A0A7M5X3M1_9CNID/42-151 AC A0A7M5X3M1.1
#=GS A0A437K9U9_9BACI/12-165 AC A0A437K9U9.1
#=GS A8FGZ3_BACP2/13-155 AC A8FGZ3.1
#=GS A0A3T0HT25_9BACI/11-165 AC A0A3T0HT25.1
#=GS A0A5J6PIZ9_9BACI/9-163 AC A0A5J6PIZ9.1
#=GS A0A2N5GZW5_9BACI/8-155 AC A0A2N5GZW5.1
#=GS A0A2A8SH20_9BACI/10-166 AC A0A2A8SH20.1
#=GS R6PFK0_9CLOT/5-135 AC R6PFK0.1
#=GS A0A1L3MX24_9BACI/7-154 AC A0A1L3MX24.1
#=GS A0A443J0K1_9BACI/11-149 AC A0A443J0K1.1
#=GS A0A0J1ILF2_NIACI/12-165 AC A0A0J1ILF2.1
#=GS A0A2N5G465_9BACI/4-155 AC A0A2N5G465.1
#=GS A0A2C1L180_9BACI/18-161 AC A0A2C1L180.1
#=GS A0A099WDI4_9LIST/12-168 AC A0A099WDI4.1
#=GS A0A1Y2AQH6_9FUNG/136-198 AC A0A1Y2AQH6.1
#=GS A0A7X2J061_9BACI/13-161 AC A0A7X2J061.1
#=GS A0A3A1R6V6_9BACI/7-151 AC A0A3A1R6V6.1
#=GS Q8ERI9_OCEIH/13-163 AC Q8ERI9.1
#=GS Q813N6_BACCR/13-166 AC Q813N6.1
#=GS A0A0A3J7Y4_9BACL/108-201 AC A0A0A3J7Y4.1
#=GS A0A0A8JJJ6_BACSX/7-160 AC A0A0A8JJJ6.1
#=GS A0A5C8NZM9_9BACI/5-149 AC A0A5C8NZM9.1
#=GS W4VP32_9BACI/1-144 AC W4VP32.1
#=GS A0A126T802_9GAMM/67-183 AC A0A126T802.1
#=GS A0A1L3MLQ0_9BACI/7-85 AC A0A1L3MLQ0.1
#=GS A0A179SN00_9BACI/8-157 AC A0A179SN00.1
#=GS A0A0M0KU29_9BACI/9-151 AC A0A0M0KU29.1
#=GS A0A6B3VZI7_9BACI/10-156 AC A0A6B3VZI7.1
#=GS A0A2U3AND4_9BACL/529-670 AC A0A2U3AND4.1
#=GS A0A221MEN3_9BACI/5-149 AC A0A221MEN3.1
#=GS A0A397FMW1_9MOLU/51-163 AC A0A397FMW1.1
#=GS D7UUN3_LISGR/9-164 AC D7UUN3.1
#=GS A0A1M7JQC0_9BACI/11-160 AC A0A1M7JQC0.1
#=GS A0A841RPX0_9BACI/9-165 AC A0A841RPX0.1
#=GS Q65FF9_BACLD/1-142 AC Q65FF9.1
#=GS I8ADV2_9BACI/9-165 AC I8ADV2.1
#=GS A0A398B1Z2_9BACI/8-119 AC A0A398B1Z2.1
#=GS A0A1L3MLM9_9BACI/1-64 AC A0A1L3MLM9.1
#=GS A0A2N5MC74_9BACI/10-152 AC A0A2N5MC74.1
#=GS A0A553ZTU6_9BACI/10-156 AC A0A553ZTU6.1
#=GS A0A4Z0GTK1_9BACL/8-106 AC A0A4Z0GTK1.1
#=GS A0A3N9URE0_9BACI/32-168 AC A0A3N9URE0.1
#=GS A0A6I1F0I4_9BACI/11-163 AC A0A6I1F0I4.1
#=GS A0A2N0ZCB5_9BACI/12-161 AC A0A2N0ZCB5.1
#=GS A0A4S4BS38_9BACI/9-157 AC A0A4S4BS38.1
#=GS A0A176J4L9_9BACI/13-172 AC A0A176J4L9.1
#=GS A0A1V2SG48_9BACI/9-151 AC A0A1V2SG48.1
#=GS A0A0M0G6W9_SPOGL/3-154 AC A0A0M0G6W9.1
#=GS A0A1Y6CGG6_9ALTE/89-220 AC A0A1Y6CGG6.1
#=GS A0A0K0GAV3_9FIRM/94-168 AC A0A0K0GAV3.1
#=GS A0A0C2VJN4_9BACL/6-151 AC A0A0C2VJN4.1
#=GS A0A161P3D0_9BACI/12-167 AC A0A161P3D0.1
#=GS A0A084GNQ7_METID/8-155 AC A0A084GNQ7.1
#=GS A0A0M1NZL9_9BACI/2-144 AC A0A0M1NZL9.1
#=GS A0A075JUG0_9BACI/7-147 AC A0A075JUG0.1
#=GS A0A143HDR5_9BACL/5-149 AC A0A143HDR5.1
#=GS A0A0M4FL31_9BACI/1-145 AC A0A0M4FL31.1
#=GS A0A0A5I5S1_9BACI/6-151 AC A0A0A5I5S1.1
#=GS A0A844LQB2_9BACI/13-164 AC A0A844LQB2.1
#=GS A0A0L0QN47_VIRPA/11-166 AC A0A0L0QN47.1
#=GS Q8YAQ8_LISMO/7-170 AC Q8YAQ8.1
#=GS A0A6I1F530_9BACI/2-80 AC A0A6I1F530.1
#=GS A0A248TG33_9BACI/4-157 AC A0A248TG33.1
#=GS A0A398BIB9_9BACI/6-155 AC A0A398BIB9.1
#=GS D3FSH8_ALKPO/8-152 AC D3FSH8.1
#=GS A0A494Z2U8_9BACI/19-173 AC A0A494Z2U8.1
#=GS A0A2V3VW40_9BACI/13-164 AC A0A2V3VW40.1
#=GS A0A495A3Y1_9BACI/10-149 AC A0A495A3Y1.1
#=GS A0A0A3IGQ1_9BACI/8-156 AC A0A0A3IGQ1.1
#=GS A0A0A3J6T5_9BACL/12-159 AC A0A0A3J6T5.1
#=GS A0A0M0G020_9BACI/9-155 AC A0A0M0G020.1
#=GS A0A235F615_9BACI/23-172 AC A0A235F615.1
#=GS A0A4Q4IE25_9BACL/9-106 AC A0A4Q4IE25.1
#=GS A0A268E7E9_9BACI/7-156 AC A0A268E7E9.1
#=GS D5DXM1_PRIM1/13-158 AC D5DXM1.1
#=GS A0A073JYD0_9BACI/12-166 AC A0A073JYD0.1
#=GS A0A7V9Z840_9BACI/10-159 AC A0A7V9Z840.1
#=GS A0A1H3TKQ6_9BACI/10-166 AC A0A1H3TKQ6.1
#=GS A0A1I5Z8G7_9BACI/11-162 AC A0A1I5Z8G7.1
#=GS A0A1J4L057_9EUKA/1-114 AC A0A1J4L057.1
#=GS A0A1G6HNZ7_9BACI/12-149 AC A0A1G6HNZ7.1
#=GS A0A6N8FD37_9BACI/13-165 AC A0A6N8FD37.1
#=GS A0A3N5ZQD4_9BACL/7-151 AC A0A3N5ZQD4.1
#=GS A0A1H8TV22_9BACI/8-116 AC A0A1H8TV22.1
#=GS A0A380BD39_SPOPA/10-162 AC A0A380BD39.1
#=GS A0A2N5MAV0_9BACI/9-156 AC A0A2N5MAV0.1
#=GS A0A4R2PA22_9BACL/1-144 AC A0A4R2PA22.1
#=GS A0A1H9R471_9BACI/6-160 AC A0A1H9R471.1
#=GS A0A3P5X0K7_9BACL/10-159 AC A0A3P5X0K7.1
#=GS A0A6I1FIK1_9BACI/9-156 AC A0A6I1FIK1.1
#=GS A0A024QDT4_9BACI/12-163 AC A0A024QDT4.1
#=GS A0A0Q3S5W0_9BACI/5-160 AC A0A0Q3S5W0.1
#=GS Q9KE86_HALH5/11-150 AC Q9KE86.1
#=GS N4WJG4_9BACI/11-162 AC N4WJG4.1
#=GS W4QL44_9BACI/11-165 AC W4QL44.1
#=GS A0A2B2B895_9BACI/13-169 AC A0A2B2B895.1
#=GS A0A075LP23_9BACI/13-164 AC A0A075LP23.1
#=GS A0A060M0U8_9BACI/13-147 AC A0A060M0U8.1
#=GS A0A0A5HVE2_9BACI/2-97 AC A0A0A5HVE2.1
#=GS A0A398B1Z2_9BACI/113-216 AC A0A398B1Z2.1
#=GS A0A1G6GY80_9BACI/12-151 AC A0A1G6GY80.1
#=GS A0A0J6CM00_9BACI/6-153 AC A0A0J6CM00.1
#=GS M7P1M3_9BACL/7-163 AC M7P1M3.1
#=GS A0A7H8S5Z7_9BACI/12-162 AC A0A7H8S5Z7.1
#=GS A0A127W2G9_SPOPS/6-161 AC A0A127W2G9.1
#=GS Q5WK73_ALKCK/13-147 AC Q5WK73.1
#=GS W1Q6B7_ABIDE/7-150 AC W1Q6B7.1
#=GS A0A2X3J711_9LIST/7-164 AC A0A2X3J711.1
#=GS A0A7G3MMR5_9CAUD/7-148 AC A0A7G3MMR5.1
#=GS A0A0M9GRF8_9BACI/11-156 AC A0A0M9GRF8.1
#=GS A0A3D8TRF3_9LIST/7-167 AC A0A3D8TRF3.1
#=GS V6IYK6_9BACL/7-107 AC V6IYK6.1
#=GS F2F0F4_SOLSS/11-167 AC F2F0F4.1
#=GS A0A147KCT2_9BACI/6-150 AC A0A147KCT2.1
#=GS YUEC_BACSU/1-144 AC O32100.1
#=GS A0A0V8JHL6_9BACI/12-156 AC A0A0V8JHL6.1
A0A1S2R6L3_9BACI/5-151 .................................itvlifayl-------FM......YP...........-LHG..F.AEV.......G.DPAVK...PNVY.HEKKIELNTN...FQEDST-.--KKYALP...EE...QKALT..FE.KKP...D...EQVI....EIKSELFKKEQ...KDNSSIQAKVKQLKLF..EK....NDA...AI.DTASM........QEgqtENEQSF.S.F.SL...TLLLGI..I.L...L...L..A.VII.LFF.ILVPRMM............
A0A135W0U0_9BACL/5-159 ..................imcialfismfgwtltaivgkads---------......--...........----..-.-NE.......S.IEDLE...PLLY.ERLKFKKNTD...YLHDQKK.IEMKNTIP...VR...QFDIQ..FD.GSQ...K...LPDR....SDRSYLFQSSN..rEKASTVAVKSREIGLF..KN....EIN...LK.KKDSV........QM..pADEPAG.T.S.IR...TTIFIG..M.I...V...I..V.LIV.LFT.FFIPKL-a...........
A8FA33_BACP2/607-690 ............................mtpadanisneviq---------......--...........----..-.---.......-.-----...----.----------...-------.--------...--...-----..--.---...-...----....----FL--QTN...TETATVAIESKNKDMF..SN....HQT...VS.NAKND.......lKK..gEKQGAG.E.S.WV...YFACIA..V.L...I...I..F.VAV.MIV.YFLRK--n...........
A0A7M5X3M1_9CNID/42-151 ................................sitvqqptfa---------......--...........----..-.---.......-.-----...----.----------...-------.-NAQASLK...NE...KLSLT..LT.KTK...D...EAAG....FYRCKLLVYDE...TSSSIQTVQSSLVRLI..AQ....DKE...AI.AASQA........--...REKEEK.E.R.NI...IIIGIS..V.A...LvglI..V.IIV.VIV.ILIKR--rn..........
A0A437K9U9_9BACI/12-165 ................iiclvvcfmginvyfsygnmkkayae---------......--...........----..-.TKS.......N.IDELA...PNEY.EGKSTDKNTD...LLDEDGS.STSKSEIP...EE...QKQLT..FE.GEK...T...FSAD....DVKNKLFQK--...AATNKIEQNAEQLGLF..TG....DDE...TV.KMGKT........EDi.qSDAHSS.L.S.LF...LGILIA..V.C...I...V..L.LGI.VLT.V------fyrt........
A8FGZ3_BACP2/13-155 .......................................gvm--SLFL--L......IP...........AAFA..A.GED.......T.DTNVK...PNEY.QEKKLDINSS...ILRDQTK.YEQSKKTS...TV...KTDIH..FA.EPP...K...TPGG....SLSPQLFSDLK..eNPPKTSAHMMEEMNIS..FR....DAA...VS.TPSGE........--...-DQEKQ.S.S.AL...LPIIFG..C.F...I...V..F.GIV.VMF.ILIPKV-n...........
A0A3T0HT25_9BACI/11-165 .......................tvfllgvlsvftlhplaed---------......-P...........--SN..Q.NND.......G.KIRIE...VERI.GQEDKE--TQ...DLKETEL.EKTLPDLF...KE...QTQAV..IK.QKQ...D...ETNKs.meQLQQTIFEAPI...KADRTTA--ELKTALF..SD....DNM...LK.YADAS........KQnkePKNEKG.I.NsKT...MAALFG..S.V...L...L..-.VSG.TIL.VRMRQM-f...........
A0A5J6PIZ9_9BACI/9-163 ........................iiliifcaallcffksge---------......--...........--VL..AdENK.......T.IDELE...PLLY.EKLEFKKNTD...YLHDVKK.TEMKNTIP...VK...QFNIY..FD.GRN...K...LPDR....NDSSFLFQHAE..rGENSTVAARSVELKLF..TS....GDK...ET.KVQTN........TS..fQEEESS.S.N.NL...LIFIFL..S.I...I...V..I.GII.ILFtVFLPKL-a...........
A0A2N5GZW5_9BACI/8-155 .............................ilfliaaflivyk---------......--...........SDPA..M.AEP.......N.IDQLT...PNTY.EKKEFNKNTD...FLHEKSL.SERRQSIP...EE...QKGLT..FI.KPS...S...DPME....KIQEQLFSQST...KENNTIRAKAQQMQLF..SG....EEE...RQ.FITEE........DT...GTTAEK.E.S.GL...SLLYIV..L.L...V...A..G.ILV.VFA.FLIPKMA............
A0A2A8SH20_9BACI/10-166 ........................................nl--SLFLFLGsf..aaLPmr.......caAESY..L.NDN.......G.KMEFK...VDRI.EQTDQEKMNK...GEQETEL.DKTQIELF...NP...EVEKE..IA.EKQ...K...KEKKq.mqELRESLFLN--...-TKTNDDIKDTKESLF..QK....NYA...VQ.MNSSEt.....nnNQ...STTGTP.I.S.TT...MTVLLI..G.G...I...L..L.ICS.GIY.AIIRKT-g...........
R6PFK0_9CLOT/5-135 ...................ddtekvlennansdinfdtsvlq---------......--...........----..-.---.......-.-----...----.-------EKN...ETYSSLT.DTYGIDLF...TD...QYEEK..IQ.EVH...L...KEYDa.yqKIEKKLFETD-...LESGKNEYEKIQDQLF..LY....TSS...EV.KKE--........EI...-KRTDN.T.L.GV...NIAITG..I.M...V...I..L.FFF.VFF.LIF----dkk.........
A0A1L3MX24_9BACI/7-154 ......................................vkvf-----LCLV.....iLTlyh.....laeTTQV..Y.GET.......T.IDELE...PNDY.QKNKGNK--E...YKLNQQQ.SNQRSSIP...EE...QKTLT..FE.GEK...V...SNDD....QVLQSLFSSEV...KNSNTIKAKAEGLGLF..SS....EEK...VA.QSSVE........D-...-SVTSK.G.S.PL...TLLIIV..L.G...S...I..C.MLL.LIV.IL-----vvwgk.......
A0A443J0K1_9BACI/11-149 .............................gvaavfligfssv---------......--...........---S..F.GAE.......E.PARTD...PAEY.QEHEIRSNLR...--KDFTS.EEAQEPVP...EE...VRKLQ..FD.QPR...E...QEYD....EMIHTLSFTG-...EDKVTTEMIASHIGLF..DT....ENP...LP.QQTPN........--...-NDDSS.A.A.WL...PWALGG..V.V...V...A..L.FLM.LFL.YILPKG-f...........
A0A0J1ILF2_NIACI/12-165 ...................................iflslil--FVFMAIF......-Sw.........lTEQT..A.RAD.......SlIDRLQ...PNEY.ESSRNLKNTD...FLKESSQ.SSKTDALT...AE...KRAIS..FD.GSK...V...NDHD....EWKGQLFTQKM...ETGSSITRKAEKLQLF..TD....DEE...NV.HYRVDr.....igEE...NSTELS.M.A.LL...ISILIG..I.C...L...L..L.LIL.ILF.V------fyrs........
A0A2N5G465_9BACI/4-155 ........................................ks---FIIALM......LPaai.....flnGNSA..G.ASP.......D.IDTLT...PNTY.EKKEFDENTN...FLHEDSL.YDNKKAIP...EE...QKGLT..FE.KQK...S...NPLD....SVKDQLFIGEG...KTTNTITATAERLKLF..SD....MDH...NN.KFEVS........EN..tENNTND.N.S.RL...MILYIG..L.L...A...V..G.IIV.MLV.LLIPKMA............
A0A2C1L180_9BACI/18-161 ......................................afml--FIFFSLGf....aSP...........VKGS..T.NIE.......S.IEELS...PNEY.ERKTGNKDTD...LIEGDAL.TKEKHQIP...EE...QKILT..FK.RKK...I...FNVD....EINAEIFKKEN...QNTNTIIHQAKQLNLF..SG....SQS...IK.VVKTE........--...-EDSKS.S.S.SL...SLLILG..F.I...I...F..C.LI-.MLT.IV-----fvt.........
A0A099WDI4_9LIST/12-168 ...................................atsmvvg-----LSLA......LPtatl...aatdEDSY..L.GDD.......G.KMEVQ...VDRA.TKTEAEKAAE...KDKKQTAaEEYQLNLFskeNE...ARDAE..IK.AYE...D...KQLK....DLKASLFAD--...EGTKVDASKVTRATLF..KE....NTS...AA.QINTT........DA...-NETEK.E.S.KT...IWWVLG..G.I...A...V..L.ICG.LLY.TLVRKVW............
A0A1Y2AQH6_9FUNG/136-198 ....................................ctvdns---------......--...........----..-.---.......-.-----...----.----------...-------.--------...--...-----..--.---...-...----....-----------...--------KYQCNKLT..GE....EKV...SN.KTSEKq......eEK...NDDSSS.S.N.IT...LYIIIG..I.G...I...I..V.GAV.IIG.IVIR---vc..........
A0A7X2J061_9BACI/13-161 .....................................lffvt----VIVIL......LPms.......aaLAEG..A.EER.......G.RLNVK...LDRI.SGSKEDQAK-...--RKTEL.ENVFPELF...KE...ETKEL..IH.STQ...V...KQEEa.leDLYQSIFEM--...ESQADATTALVQKSLF..TE....SYA...AP.TADRR........VD...EEPGEG.T.D.HV...LLVSAV..G.F...I...V..M.IGG.IVF.TMMRQV-m...........
A0A3A1R6V6_9BACI/7-151 .........................................a-ILILMSVIgt.syaIP...........---V..S.ANT.......N.INELI...PNDY.QDNKFKKNND...LLHDQS-.STEKVEIP...EE...QKGLT..FK.EAA...G...SRLD....ALKQRIFQGEE...KGTNTIKARSENLKLF..SG....AEN...SA.RLGDL........EE..tPQDSSS.L.S.VL...ISVFAG..V.C...I...L..L.LIL.VIV.I------wnr.........
Q8ERI9_OCEIH/13-163 .........................................a-SSMILLIL......LPig.......vsADTG..S.EKD.......G.SMQMQ...IDRI.IKDKDEKNE-...-LRETEL.ERLFPSLF...TT...ETSEE..IN.EKV...N...AEEDk.ieDIEQNLFSE--...DVEGNVAIQEVKDSLF..QS....DYE...SV.AASSGn......aEE...ESTSSS.S.S.NI...ILMTFA..G.I...A...V..A.LCG.GLY.VLMQRL-l...........
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A0A495A3Y1_9BACI/10-149 ......................................nivl--IIILMVG......SP...........---V..L.ADD.......S.TIKVE...PNIY.KGKDININRN...-FQETE-.--QKKPLP...EE...QKNLT..FE.KEN...K...TETD....RIEEQLFLSSN...IETNTIAAKAQQFNLF..SE....QDK...RA.IQLTD........EA...ESVQNN.S.T.IM...ILMIIA..V.S...L...V..I.G-T.MFF.FIIPRM-k...........
A0A0A3IGQ1_9BACI/8-156 ...........................ysvllavvflwmvsd---------......--...........TDLA..F.ASP.......S.LEELN...PNEY.KDKQFKDNTE...YIHNDPL.LEKREHLP...EE...QKLLD..FL.PKN...Y...DANE....EMKKQLFQEGF...EEHKTTAYESTKLLLF..TN....SEK...EV.KTEDI........KS...-RSLVN.T.K.GI...KTFYIG..L.L...L...G..L.LFL.TFL.ILLPRF-i...........
A0A0A3J6T5_9BACL/12-159 ...........................alslwlmvgsgngsg---------......--...........---Y..A.MTN.......D.INSLN...PNEY.KENDFKDNKE...FLHNNSL.LENKKGIP...DE...QKQLD..FI.PKD...V...DLNE....KMKAELFVKNF...QDRKTVAYESMKLGLF..SD....DIE...TA.KVAVS........QS..iSKNDGG.N.K.GL...QYIYIG..L.L...F...V..C.III.VLI.WLVPKMV............
A0A0M0G020_9BACI/9-155 .................................illvailas---LF--IM.....gAP...........---V..Q.ANT.......D.IEDLV...PNDY.QDNKFRKNTD...LIHERNLyNNERSNIP...EE...QKGLT..FD.GTG...S...DTSG....ERLEALFQGTE...KDTNTIKAKADNLKLF..SE....TET...AK.LGSLE........EQ...GENSSS.L.S.LL...IIIFAG..I.C...I...V..L.LIV.VMI.A------wart........
A0A235F615_9BACI/23-172 ....................................klvlaf--VLLFTF-......LS...........SKTA..S.AEK.......N.INNLS...PNLY.EKKDRNNNTD...FFTDEPL.NEQKTPIP...EE...QKSLT..FK.MKP...D...EKWE....NIKGELFAEGS..gEEKSTVAQKAKQLHLF..SG....KNS...GQ.FLNRT........--...DETKET.S.Q.SA...LPIVYI..I.L...I...A..L.GVL.MIV.LL-----ilpgmrr.....
A0A4Q4IE25_9BACL/9-106 ........................wllagalplafiivsgyg---------......--...........----..-.-GD.......S.SSKPE...PNRF.QEENTTINTE...EIQA-DL.TNNYKKIP...AQ...VRQLT..FK.KTQ...R...DEQ-....-LLNKLFLEPG..eREKINVERETAKLGLF..E-....---...--.-----........--...------.-.-.--...------..-.-...-...-..-.---.---.-------............
A0A268E7E9_9BACI/7-156 .....................igllllivsiqlsfsnivyaa---------......--...........----..-.DAP.......S.IDELE...PNDY.EKKEKKTNRS...LLRDEGLsTTKRSELP...EQ...IKQLT..FE.GAA...D...SDE-....EKIASLFLSQT...SNRNTIKSKAVEMNLF..SS....TTE...TK.MNELE........EDt.tSSSNLS.M.S.IL...IWVLVG..I.C...L...L..L.LAI.VLY.I------wat.........
D5DXM1_PRIM1/13-158 .....................................sivli-FSL----L.....cFPi.........aAAAE..A.DDG.......N.VEEIK...PNVY.KDDPINLDPE...SLLENK-.-KEVGNIP...EE...IKDLT..FE.KEE...D...AEKE....SLKESLFANAS...AEDNTISAKAKEYNLF..SS....KNT...SY.KKERT........EQt.vSEKSSD.L.Q.WF...YLLLIG..V.G...V...V..I.L--.-FA.VLIPRI-s...........
A0A073JYD0_9BACI/12-166 ..........................................SFVLFVCLFv....aLPir.......gaAESY..L.NDS.......G.QLEFK...VDRI.EKTDEEKRNP...EQKETEL.DKRAIDLF...SE...ETTSL..ME.DRK...R...QETQe.keELYSSLFL---...DEQIVNPLKSTLQTLF..HS....DYA...VK.LEGKE.......mNQg.dKMNGES.I.S.NV...VTGLLI..A.V...I...A..L.ICI.GIY.IILRKSW............
A0A7V9Z840_9BACI/10-159 .........................................f-FFLFLCSVl...atMG...........VTVY..A.ESD.......E.WPEIE...PNQY.QRQDIELRTD...YLHEESL.LDEKGDLP...ET...QTSLT..FQ.GPA...S...SFFE....QTKAQLFLSEE...KETNTIAAKAEKLGLF..SF....VEE...QS.IPSRQ........PM...DEAERT.S.S.SF...LPWLFG..F.F...I...L..G.FLI.VIFtVIVPRM-k...........
A0A1H3TKQ6_9BACI/10-166 ......................................aaac----LLCFWl....lLPspv.....lseADSG..S.EDN.......G.KMQME...IDRI.NKNDRDSEQK...-TTMTEL.ERSFPDLF...SD...DIKIK..IE.TRQ...Q...ALENd.ieELQHSLFDNDL...SGASAAALEDIQAQLF..TE....DYT...SS.GASVN........AQe.eETKAGF.S.R.GL...LLGLLS..F.I...G...V..I.S-G.GVF.VMMRKV-l...........
A0A1I5Z8G7_9BACI/11-162 ........................ilpliilmfigtsfivva---------......--...........----..E.EPK.......E.AKDLD...PLIY.EKLEFKKNTD...YLHDKQK.TEMKNTIP...EK...QFDIY..FD.GRN...K...LPNR....GDTSFLFQTAE..rGEKSTVTAKSSELKLF..SS...sDTK...KL.ELSAA........EM...KEEKSS.N.N.SV...RNILFF..G.I...I...A..L.GVL.MLFvILLPRL-v...........
A0A1J4L057_9EUKA/1-114 .....................................messr---------......--...........----..-.---.......-.-----...----.----------...-EKETT-.SEDKEQIP...IS...QKEET..IQ.YSSssiD...EDTD....KLTLSMLEEPT...TPRNEFNSDLETDERT..RT....EIN...SS.IDAGD........EE...-DNKSQ.T.G.MI...VGVVIG..V.I...V...I..I.ICI.ILV.IL-----filkrks.....
A0A1G6HNZ7_9BACI/12-149 ..........................................SVSILLMIF......SP...........-TSL..A.EE-.......-.-SRTD...PAQY.REHNVELDAN..rNFKKA--.EREEVEIT...EE...VDQLQ..FT.DPR...G...ELYQ....EVVDAVSLSLE...ESPFSTTQVVSEMHLF..QE....VNA...LS.EEVSA........--...-ENGTA.T.S.WF...VWALGG..M.V...V...A..L.LVF.LFG.YVIPKW-f...........
A0A6N8FD37_9BACI/13-165 .......................................lfs---TILLILg...vnIHl........vsAESS..S.NNR.......G.SLEFK...IDRI.EKSKETDRE-...-ISETEL.EKVFPSLF...SE...ETETT..IH.DQQ...T...EEEKl.lkELEQSLFSM--...ETEPNETLEDVKQTLF..TE....DYT...VTvSQSIQ........DQ..eEEKNSG.L.G.NS...VIAVFS..G.F...A...F..L.LCG.GVY.VMMRKM-l...........
A0A3N5ZQD4_9BACL/7-151 .........................cvsiltgsiilsnttvl---------......--...........---A..E.EDN.......G.QLNID...INRI.NEDKTKVDTT...---DNN-.VVETEDLF...TD..eSAQLEnyIK.QTK...K...KEEN....STLNSLFQ---...KDFMNQEIELSTNQLF..QE....KIS...VS.NIQLE........EE...-KKESQ.M.N.RW...LFFTIL..F.T...I...I..TgLCF.GIF.FLQKKL-n...........
A0A1H8TV22_9BACI/8-116 ...................................aegisve---------......--...........----..-.---.......-.-----...----.----------...--NETEL.DRQYSELF...SK...DTELT..FH.IQL...E...KINDh.veDVKAELFVT--...NIEKRSFIEETRPKLF..LK....DHT...IP.LSIEL........M-...EQDYKG.A.N.LI...LLGIIV..L.F...M...V..A.I--.LMV.Y------lnikn.......
A0A380BD39_SPOPA/10-162 ........................................mw--SLFICLFm....mFPlq.......tfGEGT..T.NSD.......G.KMRFK...TERI.GEKEGVQSN-...--KETEL.EKIAPDLF...KE...ETIEA..IE.KKQ...Q...ELKSe.veNLEKILFKT--...SKITDSSIQDTKKSLF..AN....DYQ...AP.KALAEmd....dsEV...SEEGIS.S.N.VI...LYGLLG..T.V...I...L..L.C-G.GIF.TYMQKV-l...........
A0A2N5MAV0_9BACI/9-156 ....................................ivtlia----VLGIL.....nIP...........--GY..A.AAD.......D.NRPVE...PNTY.KEKEIDLQTE...YFHEDSL.LKEKEQLS...EE...QKMLT..FK.RQE...Q...EFFE....QIKEGLFINAE...SKTTTVSANASELNLF..SR....ESF...SS.PSDVI........AS...DRGEER.E.S.SF...LPLVLG..L.I..lT...L..C.ILY.MFL.ILVPKM-t...........
A0A4R2PA22_9BACL/1-144 ........................................ma-----LLIL......IP...........AAVA..S.AET.......D.IEKLK...PNVF.KDKHVDLNTD...YLHDNSR.YKQKYAIP...EE...QKQLT..FK.KDD...K...DPLK....KVKEVLFNGSK...KENNSITAKSAQLHLF..SG....KPE...ST.LREMN........DDk.gSTGSST.L.M.IL...YLTIIA..G.G...I...L..L.LFL.LLI.-------pwmmkk......
A0A1H9R471_9BACI/6-160 ...........................mmllvllaiiflfvd---------......--...........TQVVlaA.EDK.......T.IDELE...PVIY.EKLKFKKNTD...YLHDEKK.TEIKNTIP...EK...QFNIY..FD.GRK...K...LPNR....SDTSFLFQTSI..rGEKSTVAAKSSELNLF..MD....KSK...GE.KQLPD........SQ..fNSYETA.S.N.NT...RTMIFL..A.I...I...V..IgLIA.LFI.VVLPKL-v...........
A0A3P5X0K7_9BACL/10-159 ..........................ivivlvsllveenvlg---------......--...........---A..K.EDD.......T.IHDLE...TLLY.EKLKFEKSTD...YLHDEKK.VEMKNTIP...VK...QFNIY..FD.GRD...Q...LSKK....GDTSFLFSTAE..rGARSTVAAKASELKLFigKE....EKK...SV.LTEGN........EP...VEGKSN.N.R.TL...ILVLIG..I.I...I...A..S.LIL.LFI.IVLPK--q...........
A0A6I1FIK1_9BACI/9-156 .......................lpfilvlffvnadpvlsaa---------......--...........----..-.---.......-.GPAVQ...PNEY.KKGEIEVETD...DFHEGSL.FEKKNKTP...EE...QKSIT..FD.PPA...A...SLDD....SIHSHLFLGS-...QESNTIRSRAVKMNLF..NG....KPKeltVI.KQTEE.......nET...-GVALQ.Q.P.KW...LFIFIG..F.I...M...L..S.LIVyLFF.VLVPKI-t...........
A0A024QDT4_9BACI/12-163 ....................................illfsi--SLLMLQ-......TS...........VDAS..P.ANN.......G.QLQLE...IDRI.IESEKEQTQT...--DKTEL.EKRFPTLF...SE...QTQST..IN.TEE...K...QNKAs.meRLQQTLFRT--...ETETNKTIRNVREGLF..EE....DYS...AA.SVQSQm......dKTd.dKESTNA.M.N.SI...MLIVFT..G.L...A...C..L.LCV.GLY.FMMRRM-l...........
A0A0Q3S5W0_9BACI/5-160 .......................................qft---LLFCVL.....mISwll.....aqtTVHA..N.EEK.......S.SKELE...PVIY.EKLKFKKNTD...YLHDGKK.TEMKNTIP...EK...QFNIY..FD.GRR...Q...LPNR....KDTSYLFQTSE..rGEISTVSAKTSDLKLF..SN....ESK...GE.KEQSGts...lnmEE...PAGNKT.R.T.MI...LLAIIA..V.G...I...V..T.L--.-FM.VFIPKM-v...........
Q9KE86_HALH5/11-150 .................................aiamlltgf--SPLLSF-......--...........----..-.GAE.......E.PTRTN...PAEY.REHEIRPTLR...NDHSSGE.AREPVRVP...DE...VRKLQ..FD.QPL...E...QEYD....EMIRALSFNG-...EDKVTTEMIASHIGLF..ET....ENP...LP.QQA--........--...LDDHSS.V.A.WL...PWALGS..A.V...V...A..L.FLT.LFI.YVLPKG-f...........
N4WJG4_9BACI/11-162 ....................................ilstcc----L--LL.....lMPvq.......asAEES..N.EQN.......G.EMNWK...VDRI.IEKNKQQQN-...-DQETEL.ETRFPELF...KD...ETAEK..IA.SVK...Q...KNQAs.ldQLENGLFSM--...EMDRDTTIKETKESLF..AT....DYE...AP.KTASTs......nEE...NSNDSM.F.S.TL...LMIGLV..G.V...V...C..V.ISG.GIY.VLYQRL-i...........
W4QL44_9BACI/11-165 ......................................mvym---LIISLF......LPsfa....vlaeEQSS..T.AER.......G.KLNVD...LDRI.SGSNRGGDQT...-NTVTEL.EKVFPELF...RD...ETKEV..ID.TKQ...L...EQEKw.leRLQQSIFEM--...ESQTDATVALIQESLF..TE....SYT...TP.ATESRa......sEE...RSDEGA.N.N.VL...LFSIMG..M.I...T...M..I.G-G.AVF.MMMRQ--vm..........
A0A2B2B895_9BACI/13-169 .....................................vlagf---LL-MFS.....lQP..........lADET..L.DHS.......G.KIRLQ...TDRI.GQDAVDRKTLdtqDYQETEL.ERLAPDLF...KE...QTQTA..LK.TKQ...I...ELEQs.tsDLQQGLFVT--...PSKSDITLKQTESALF..SS....DYS...VQ.YNTAS........AQnelDDQHDGfL.N.TK...TITTFL..G.M...V...V..I.GCG.GLL.TMMRKM-h...........
A0A075LP23_9BACI/13-164 .........................................i-FTIILLIL......LPie.......vsAEVN..S.EENe.....rG.SLQMQ...IDRI.QKEKDVGAD-...-IRETEK.EKVFPGLF...ND...ETTDD..IQ.QKA...E...VKKEd.veALQDSVFTL--...DINQQAPLEEVQDKLF..TA....DYT...SE.AASGQ.......kET...DQTETD.SgN.GV...LYFLIG..I.A...L...A..-.LCI.GLY.MMMRKL-l...........
A0A060M0U8_9BACI/13-147 ........................................cs--VLLLSSV......MP...........--SF..A.QE-.......-.-ERVE...PGVY.KEREVLLELR..qYKPEAE-.-QREIRVP...EE...QKILT..FT.QPL...E...ETYT....ELQDTLFASS-...AEADHQENVAASAGLF..TE....EKV...LA.RHV--........--...VPVEEN.G.N.VL...PWILAA..V.A...T...V..L.VSI.LLI.YIIPKT-a...........
A0A0A5HVE2_9BACI/2-97 .........................................i---------......--...........----..-.---.......-.-----...----.----------...-------.--QKEELP...EE...QLHLT..FE.SKD...Q...DKEE....TLITDLFQSNL...TNKNTIVAQSKQLQLF..AD....EMD...VK.RGERN........TQ...-QIIHS.I.S.MT...AVMLFL..L.F...I...A..I.A--.LLF.LIVPKL-k...........
A0A398B1Z2_9BACI/113-216 ......................................aals---------......--...........----..-.---.......-.-----...----.----------...-------.-DKKNKIL...EE...QLKTV..FSiKPK...K...DSYN....EVLTSIFTSNN...MENNTITAKAKELKLF..SG....DAS...GF.QNDEE........EN...ADSGLA.N.K.GV...IITLAV..L.L...L...L..F.VIV.LFA.LLIPKMV............
A0A1G6GY80_9BACI/12-151 ........................................ai--AILLTVS......AP...........--LS..F.GAE.......D.ATPTN...PAEY.QERTIRPELR...KDDTEKD.SQEPTRVP...EE...VNQLQ..FD.QPL...E...QEYN....EMVSALSFTG-...EDKSTTAAVASHIGLF..HV....ADP...LP.QEAPH........--...-NENAS.V.A.WL...PWVLGT..V.V...A...G..L.LVT.LFV.YILPKG-f...........
A0A0J6CM00_9BACI/6-153 ...................................islitli----FL--Cg...hlVP...........-VAV..G.ANT.......D.INELL...PNEY.QKNKFKKNTD...FIHDSSN.TKEMGEIT...EE...QKTIV..FN.GDK...S...FNPE....PTINQLFLSMS...TENSTIKDKAENLKLF..SN....TET...TG.FQSKI........NE...-DTQTS.S.S.SF...QL-LIG..V.L...I...G..I.FLL.GLV.IVL----viynr.......
M7P1M3_9BACL/7-163 .................................lalvllagt--------Vi...aaQP..........vSADE..P.EEN.......P.AETLD...PFEY.KELEFRKKTE...YLHDRGQ.VEMKNTIS...EA...QINLD..FS.EEV...R...IPSP....IEVSELFLEPG..rSETGTAAAKAAELGLF..TE....EAP...VS.EEAAAk.....epQQa.aEEQSEG.T.P.VR...NWIFIG..V.I...V...L..A.VAG.LFA.FVVPA--ll..........
A0A7H8S5Z7_9BACI/12-162 ......................................gscc----L-LLL......MPfs.......vsAEDT..P.DEK.......G.EMDWK...VDRI.KQ-DNSTNEN...SGGETEL.EQEFPELF...KE...ETRAT..IE.SVQ...K...EKKEs.leETEKALFTI--...NPEKNTTIADTKESLF..TS....DYV...VP.ETSTD........QQ...QEDEGG.S.S.WF...NNALMA..G.L...T...G..L.ACV.---.-------igaavytmiqrf
A0A127W2G9_SPOPS/6-161 ......................twlllvilliawtaghstvq---------......--...........--AA..P.DDE.......P.NLDLE...PVVY.EKLKFKKNTD...YLHDSKK.VEMRNTIP...VK...QFDIY..FD.GRR...Q...LPKR....SNGSYLFQTKE..rGEKSTVAAKTAELGLF..TS....AEK...SG.KKTNAvk....ivE-...-ENTAT.N.K.PR...TLILLA..I.I...V...A..G.LVT.LFT.FFLPKL-v...........
Q5WK73_ALKCK/13-147 ..........................................CVTLLLSLA......TP...........--SF..A.EE-.......-.-ERVE...PGVY.KEREVLLELR..qYKPEAE-.-QREIRVP...EE...QKILT..FT.QPL...E...ETYA....ELQDSLFASS-...ADANREENLAASAGLF..TE....EKE...LV.RQV--........--...VQAEEK.V.N.VL...PWILAA..V.A...T...V..L.VSV.LLI.YIIPKT-a...........
W1Q6B7_ABIDE/7-150 ...................................wlviivg-------ILfg..lsMP...........---I..Q.ARD.......G.SLKID...TNRY.DATKSNEIT-...-YSEQE-.-RLFAKLF...TT...DLTEL..IN.RHL...Q...RQEAp.rqALAPQLFQAP-...IQALDRTAKAKQVA-F..TS....DHP...TQ.RVERY........NHr.lAITDQP.K.K.PY...LWLIFC..L.A...L...A..V.FCG.LIY.Y------yyfr........
A0A2X3J711_9LIST/7-164 .....................giffllcfsffalnvtvslaa---------......--...........EDGY..L.END.......G.KMEMK...ADRL.QKSDEEKTQE..aNPQETML.DELKLPLF...TE...QLDKK..IE.AQK...K...AEAEk.yqKLQDQLFTG--...KDVSDQTVKKTKDKLF..EG....EYA...SK.TDQEV........VE...DEEEKT.N.S.KM...VMAIVF..G.I...V...L..A.LAG.GIY.FASRNV-m...........
A0A7G3MMR5_9CAUD/7-148 ....................................rlfvlc-FSVI--VM......EP...........-SLV..F.AND.......G.SLQIN...TDIN.QGKETKEV--...YYIEQE-.-AALSKLF...QT...ETTDT..IS.QKQ...AvvsEEEK....SLKEGIFLE--...DLPSNNWSTDYRELLF..NP....ETE...LA.VSSDY.......gVQ..lTEKKPG.I.S.WQ...MLALFG..L.G...I...V..V.MIW.SLY.-------qt..........
A0A0M9GRF8_9BACI/11-156 ..........................................SVSVLIAI-......MPf.........tGTVT..L.AES.......D.IESLK...PNSY.EKKDFKENTD...FLRENNL.NERRESVP...EE...QKLLT..FQ.KRE...K...KAED....DFAGTLFMTGE...KKSTTIQATSQELKLF..TE....DDN...SR.YQTAV........AS...-ESSSK.T.N.SI...TILLFG..F.L...V...I..A.LIL.MLA.IILPRMA............
A0A3D8TRF3_9LIST/7-167 .........................................s-LSLLVILAcf..saAPla......laaGTGY..L.ESD.......G.SMDLK...TDRL.QKTDEEKQEEl.kKAEPTML.DQLELPLF...TK...DLEKK..IK.AQQ...K...KDKKn.fkDMQDQLFTG--...KPVKDETAKTAQKELF..KK....TNV...AQ.ASEAEl......dDQ..aKEEKNT.E.S.KS...LFVIIG..A.V...V...V..A.LVG.GIY.FASRNI-m...........
V6IYK6_9BACL/7-107 .......................nrlllislaltaflfisgy---------......--...........----..G.ESK.......S.NVNVK...PNHF.KKQNTTINTD...EI-NTDM.ANSYHKIP...SE...VRSLT..FI.QPH...Q...DEK-....-IIKGLFLTPG..kTEKVNVKKEAERLGLF..Q-....---...--.-----........--...------.-.-.--...------..-.-...-...-..-.---.---.-------............
F2F0F4_SOLSS/11-167 .........................................g-FSILMGVGfeiesgFPln.......leTKQV..S.AAT.......E.LNNLN...PNEF.KEKEFKDNKE...YLHNESL.LDNRKNIR...EE...QKQLD..FK.PKV...L...ERNE....KIKEELFISDF...KERKTIAYDSMKYGLF..SN....ERE...IV.KTKIT........ES..iPDDDSK.S.N.GL...QFFYIG..L.L...I...A..C.IFV.VLL.WLVPKMV............
A0A147KCT2_9BACI/6-150 ..........................lwfilsfiminmvsyh---------......--...........--TV..Y.AST.......N.INKLS...PNDY.QEDSFKKNTD...LLHDQSS.SNEKLKIP...QE...QKGLT..FE.GKS...T...NTFS....ELSYRLFKNEA...RDTNTIKAKAESLDLF..TE....EQS...TR.LDGME........EN...GQDSSS.L.S.VL...MGVLAG..I.C...V...V..L.LLS.VLI.I------ws..........
YUEC_BACSU/1-144 ........................................mlSFSLF----......IP...........SAAA..A.QTE.......E.NTDVA...PNQY.EKKDIEIDTN...YLHEDTY.YEEKTELP...EE...QKDIT..FD.KPK...D...KDA-....ELIKDLFTSTN..aEDSNTIAAQSKQLGIT..FA....EKP...MT.KTSST........ET...EDEQET.S.S.LL...LPMIYV..V.L...I...L..L.GIA.GIV.FLIPKV-t...........
A0A0V8JHL6_9BACI/12-156 ...................................iallavl------LFL......ST...........SNVY..A.AND.......T.QTQVQdlaPNIF.QDEQIKLNPD...SLGQTK-.-REVENIP...EE...IRGIP..FT.DEE...K...KPS-....-LKSSLFLNDS...TTNHSIQSQVNKYGLF..TS....TES...PV.QSSSV........QDv.pEETGLK.L.Q.WV...YILLIG..I.G...L...V..L.L--.-FT.VLIPKL-k...........
#=GC seq_cons ........................................hh................s..............h....tpp.......s...plp...sspa.pcpchctspp....hp-pph..cpt.pls...cE...pppls..ap.ppp...p...pppc....plpppLFts.....pppsshstcspchpLF..op....cpp...ss.ptptp........pp....pspps.p.s.hh...hhhlhu..h.h...l...l..h.lhh.hlh.hlh.+h.h...........
//
