#=GF ID   FMP23
#=GF AC   PF17315.6
#=GF DE   Found in mitochondrial proteome
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   PRODOM:PD100582
#=GF GA   27.60 27.60;
#=GF TC   30.60 29.00;
#=GF NC   27.40 27.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   27401861
#=GF RT   Transcriptomic response of yeast cells to ATX1 deletion under
#=GF RT   different copper levels.
#=GF RA   Cankorur-Cetinkaya A, Eraslan S, Kirdar B;
#=GF RL   BMC Genomics. 2016;17:489.
#=GF DR   INTERPRO; IPR035283;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   FMP23 gene encodes a putative mitochondrial protein involved in
#=GF CC   iron-copper homoeostasis. It was observed to be induced in
#=GF CC   response to ATX1 deletion and high copper conditions [1].
#=GF SQ   45
#=GS A0A1L0B6H2_9ASCO/805-911   AC A0A1L0B6H2.1
#=GS C5DEB5_LACTC/48-176        AC C5DEB5.1
#=GS A0A1D2VLL3_9ASCO/104-153   AC A0A1D2VLL3.1
#=GS G0VK05_NAUCC/53-181        AC G0VK05.1
#=GS Q6FRB4_CANGA/65-175        AC Q6FRB4.1
#=GS I6NCX5_ERECY/37-151        AC I6NCX5.1
#=GS W1QLN0_OGAPD/71-182        AC W1QLN0.1
#=GS A0A2H0ZV61_CANAR/801-905   AC A0A2H0ZV61.1
#=GS A0A7H9AZH5_ZYGMR/48-174    AC A0A7H9AZH5.1
#=GS FMP23_YEAST/53-175         AC P38231.1
#=GS C4QZ22_KOMPG/125-204       AC C4QZ22.1
#=GS A0A4C2E7D7_9SACH/48-178    AC A0A4C2E7D7.1
#=GS A0A1E4S3V2_CYBJN/1-114     AC A0A1E4S3V2.1
#=GS B5RUE1_DEBHA/745-851       AC B5RUE1.1
#=GS J6EF29_SACK1/53-175        AC J6EF29.1
#=GS A0A1E4SVW9_9ASCO/59-153    AC A0A1E4SVW9.1
#=GS A0A376B7P1_9ASCO/70-192    AC A0A376B7P1.1
#=GS A0A1E4RR58_9ASCO/998-1104  AC A0A1E4RR58.1
#=GS H2ARQ2_KAZAF/57-177        AC H2ARQ2.1
#=GS A0A2P7YKI8_9ASCO/796-899   AC A0A2P7YKI8.1
#=GS G8ZTL1_TORDC/46-172        AC G8ZTL1.1
#=GS A0A1G4J327_9SACH/48-178    AC A0A1G4J327.1
#=GS A0A1E4RR58_9ASCO/615-729   AC A0A1E4RR58.1
#=GS A0A1E3NGH0_9ASCO/54-178    AC A0A1E3NGH0.1
#=GS G8Y7I6_PICSO/737-842       AC G8Y7I6.1
#=GS A0A1E4RR58_9ASCO/750-856   AC A0A1E4RR58.1
#=GS A0A1S7HXE2_9SACH/53-183    AC A0A1S7HXE2.1
#=GS A0A512ULI0_9ASCO/194-300   AC A0A512ULI0.1
#=GS C4Y4S4_CLAL4/691-796       AC C4Y4S4.1
#=GS A0A7H9HVK2_9SACH/46-174    AC A0A7H9HVK2.1
#=GS A0A4T0WYL8_9ASCO/49-135    AC A0A4T0WYL8.1
#=GS A0A1E3P323_WICAA/50-162    AC A0A1E3P323.1
#=GS A0A1E4SD60_9ASCO/745-850   AC A0A1E4SD60.1
#=GS J8QB50_SACAR/53-175        AC J8QB50.1
#=GS A0A448YSZ7_BRENA/78-178    AC A0A448YSZ7.1
#=GS A0A1E3QZU5_9ASCO/65-183    AC A0A1E3QZU5.1
#=GS J7SAH6_KAZNA/50-182        AC J7SAH6.1
#=GS Q6CX78_KLULA/44-174        AC Q6CX78.1
#=GS A0A2V1AYR1_9ASCO/801-905   AC A0A2V1AYR1.1
#=GS A0A1V2L649_CYBFA/44-158    AC A0A1V2L649.1
#=GS A0A1G4MCN6_LACFM/41-170    AC A0A1G4MCN6.1
#=GS A0A1S7HSM8_9SACH/53-183    AC A0A1S7HSM8.1
#=GS A3LQ95_PICST/669-775       AC A3LQ95.2
#=GS A0A1E4TTU2_PACTA/100-221   AC A0A1E4TTU2.1
#=GS K0KQ56_WICCF/57-169        AC K0KQ56.1
A0A1L0B6H2_9ASCO/805-911              .p-YLQIPDKMQ-LHEFVKELEIFRHD----D..LRSS...FKNFS--AEKILGLMQKR----IKEIYNDLPC-TNH..............ALRMS...KDN.......LIAFIKLHAKLEKLLAWNGGNTGILDTLIHSQSVFNDFED-k.
C5DEB5_LACTC/48-176                   ..EYRQLPENCGYIENFYNELEQFSNDFLTSQ..LNKS...YSDFDDCPEDLVFEIDKYIETRIIPRHSVSSAAKQDargar....ppivcETVSD...KLV.......IERFLDFSNGVKLTLRMNGGYTFIFDVMLQGKAAFDQFE--av
A0A1D2VLL3_9ASCO/104-153              .i-YTQLPDDSQFITQHYNELKIFKSHLVK-N..YNKK...FQDF--KASELLKELIFF------------------..............-----...---.......-----------------------------------------i.
G0VK05_NAUCC/53-181                   ..EYRQLPED-NPIEKYYDEIETFSKACLEKQ..LKKN...YSDFEGNPDELVFEIEKYVESQIIPKYSVLDEDREKttpsl...psmvycKTLGD...KLV.......IERYISFARAVRLALIFNGGHPFIFDLMLQGRSVFDKIGE-k.
Q6FRB4_CANGA/65-175                   ..EYRQLPDDSNYIEKYYAELDVFLQ-YLQTQ..LHKS...YVDFENDPDELVFQLEKYIELQVRSNYDA-------..............NKAGE...KLV.......IDRFVAFCEGVKLTLWLNGGHCFIFDVLLQTKGEFDKLET-t.
I6NCX5_ERECY/37-151                   ..EYKQLPEDSNYIERFYTELDQFRNEFLIPH..HKKS...YSDFNDSPNDLVFELDKYIELHVIPKYYAGTT----..............ISLAN...KLV.......VDRFLDFSRGVKTTLRLNGGHTFIFDMLLQSKKVFDDLQKK..
W1QLN0_OGAPD/71-182                   ..EYKQLPDDSQFIEKHYDELRHYREK-----..LGKS...FGEFG-SASELFRELSKF-KPKFGSRNTRTVPDTEV..............LQDMD...QLA.......VVKFDRFINDLAITLRLNGGHLFTLDLLLHNKELFDSFEQ-e.
A0A2H0ZV61_CANAR/801-905              .p-YVQIPEKL-GLHDFVEQLAIFRDE-----..LQKP...YKDA--SPTEVLDLMEKR----TKEIYNDG--NSNP..............TSRMN...KDN.......MVSFIKLHAKLKKLLAWNGGNTAILDTLIYSQKVFDNFEA-k.
A0A7H9AZH5_ZYGMR/48-174               ..EYKQLPENSNYIEKFYDELRLFSTEFLAKQ..LNKS...YTDFENDPDELVFQVEKFIELQIIPKHSELRESSTVspmq......svecKTLSD...QIV.......IQRYLDFARGVKKTLMFNGGHTFIFDAMLQAKEVFDSFQT-q.
FMP23_YEAST/53-175                    ..EYKQLPEDSNYIEKHYKELQVFLNEFLIKK..LNKT...YADFEGDPDELVFQLEKFIELEVTPRYTNHSAPDGCee..........rfKSIGD...RIV.......VDRYLDFVKDVRLTLLLNGGHSFIFDVMLQAKEVFDKMQKE..
C4QZ22_KOMPG/125-204                  ..NYKQLPEDSDFIEKHYDELKYYRNL-----..LKKP...FNSYK-NANDLLRDLYKIEETDPVAA-TVPKTQETA..............ETTEA...ESK.......LSQFEKFI---------------------------------s.
A0A4C2E7D7_9SACH/48-178               ..EYKQLPEDSNYIEKFYDELQVFSQEFLEKQ..LQKK...YADFEDCPEELVFQLEQFIELQIIPKYSKPANETGDtrpgfp..vrsiqcQNIGD...NII.......IERYLDFSKSVKLTLMLNGGHSFIFDVLLQAKSAFDNMQRN..
A0A1E4S3V2_CYBJN/1-114                ..EYRQLPDDSQYIEKFYNELSTFHDELKGNTgiPQSS...FSEFEDNPNALIATLEDFIQDKILSVYGGR------..............VDSGA...KVV.......IQRYGEFLHNVKTTLILNGGHPFIFDVLIQNKQLFDGFDK-..
B5RUE1_DEBHA/745-851                  .i-YTQIPDDLD-LHKFSNELEIFRE----DE..LKGS...YSEYS--AD----QIESLMNKRMAEINN-GTENFNV..............TSRMN...KAN.......LHEFMRLGRRLARLFDINGGNTEILDTLIQSQSIFDKFEK-s.
J6EF29_SACK1/53-175                   ..EYKQLPEDSNYIEKHYKELQVFLNEFLVKK..LNKT...YADFEGDPDELVFQLEKFIELEVTPKYIDFSASDHHkg..........kfKSIRD...RIV.......VDRYLDFVKDVRLTLLLNGGHSFIFDVMLQAKEVFDKMQKE..
A0A1E4SVW9_9ASCO/59-153               ..NYQQIPDDSKFIDKYYNDLIEYKLKL----..DVVE...YNDFK-TISNLFKSLSEL-----KP-----------..............---SD...EVE.......IKKFDLFIYDLIKLFKMNNCHLFILDLLIQNKELFDKFET-i.
A0A376B7P1_9ASCO/70-192               ..EYKQLPEDSQYIEKFYDELETFQL-FLKSE..LHKS...FSDFEDSPQELVFELEKYIQMELLPRHTKLCDDDIKst.........fkfPTMGD...KLV.......IDRFLDFLHNVNITLVLNGGHTFIFDIIIQSKKSFDEFQKQ..
A0A1E4RR58_9ASCO/998-1104             .p-YVQIPDDLE-LHKFTKELEIFKN----DE..LKSS...FKNF--SPDKINALLDKRINE-IYNDLPN----TNL..............ASRLS...KDN.......VYDFMRLSKRLTRLFDVNGGHTGVLDTLLQSQSVFDNVDS-m.
H2ARQ2_KAZAF/57-177                   ..EFKQLPEDSDYIENFYNELEDFSEEYLKKH..TKKS...FADFEGEPDDLVFQVQKYVELQIVPKYTVEAGDQSRi............yRSIGD...KLL.......VERYIEFIKAMKLTLRLNGGHTFIFDLILQSHAVFNEWES-n.
A0A2P7YKI8_9ASCO/796-899              py--VQIPEKL-GLHDFVEHLSIFRDE-----..LQKP...YKDAS--ATEVL----DLMEKKTKEVYNGA-NSASL..............KINTD...NLV.......--SFIKLHAKLKKLLAWNGGNTAILDTLIYSQKVFDNFEA-k.
G8ZTL1_TORDC/46-172                   ..EYRQLPEDSNYIEKFYDELETFSNEILIKQ..LKKT...YADFDDEPEELLFQLEKYIELQIIPKHSDTQQAANDgpir......siqcRTLSD...KII.......IERFLDLARGMKLTLLLNGGHTFIFDVLLQAKQVFDKMQQ-t.
A0A1G4J327_9SACH/48-178               ..EYKQLPEDSNYIEKFYNELERFSTDVLHGQ..LKKT...YTDFDDNPDDLVFELEKYIELQVIPQHSSYVEKTADfsasrp..lstihcKSVGD...KLA.......IDRFLDFCSGVKLTLRLNGGHSFIFDVLLQAKSSFDEFEKK..
A0A1E4RR58_9ASCO/615-729              .s-YTQVPDDLE-LDKFINELTILKKDVLK--..--KP...YKSFT--SS----ALNKFIDEKIDEVFNSKFHGP-Kifkp......vnstEFGIH...RGN.......VYQFVRLSKRLTRLFEVNGGNTEVLDFLIHSQSVFNDMEA-k.
A0A1E3NGH0_9ASCO/54-178               ..EYKQLPDDSQFIDKHYDELVKYRDLICG--..VGGQ...FGEIS-GVPELFLRLSKVHPKHVVASTDGPEQTETQaiq........gpaKEMKDsflKMQ.......VDQFDQFVIDLMNALRLNGGHLFVLDLLIYNNQVFDHCER-t.
G8Y7I6_PICSO/737-842                  .a-YKQIPDDLE-LHKFIKELQIFRDD----E..IKRP...YSEI--SSDELLRSLDKCIDVIHNSEVYTP------..............SKRMN...KQN.......IHNFMRLSKRLTRLFEGNNGYTAILDTLIHSQSVFDNFEKK..
A0A1E4RR58_9ASCO/750-856              .p-YVQIPDDLE-LHKFTKELEIFKND----E..LRSS...FKNF--SPDKINSLLDKRI----NEIYNDLPN-TNP..............ASRLS...KEN.......VFEFMRLSKRITRLFDMNGGNTQVLDSVIQSQSVLDSVEA-k.
A0A1S7HXE2_9SACH/53-183               ..KYKQLPDDSNYIEKFYDELQLFSQDFLEKQ..LHKK...YTDFDECPEELVFQLDQFIELQIIPRYSKPVKETGDnhaafp..lrsiqcKTISD...KIV.......IERYLDFAKGVKLTLMLNGGHTFIFDVLLQAKSVFDNMERN..
A0A512ULI0_9ASCO/194-300              .p-YIQIPES-LGLHEFAEELSLFRS----HE..LKKN...FSDL--SAQNLLHTMEKRLK-EVYDDVSD----APH..............TQGVC...KQN.......LVRFYNLFPKLQKLLAWNGGTTAVLDTLLESHNVFKSVDE-k.
C4Y4S4_CLAL4/691-796                  ..EYVQIPDY-LMLHSLHSELEIFKT----DE..LKRD...YSEL--TSEEVLKSLEARVQEVLQHGSTS-----SE..............SRITS...K-N.......ILHFKKLLSRLKTLFAVNGGNTEVLDALIRSQNTFDQFES-q.
A0A7H9HVK2_9SACH/46-174               ..EYKQLPDDSNYIEKFYDELEVFSKDVLEKR..LNKT...YTDFEDDPEELQFQIEQYIELEIIPRYSVYESSGTSddrsi....klvqcRTIRD...KIV.......VERFLDFAKSVRLTLMLNGGHTFIFDILLQAKKTFDAMQK-t.
A0A4T0WYL8_9ASCO/49-135               ..EYRQLPDDSQFIEKHYHNLRHYRDLVCG--..VGGQ...YEDIG-DISELFLRLSKHVP--IKDKRN--------..............-PFWE...K-Q.......LEQYNQFVTDLVATLRLNGGHLFV-----------------..
A0A1E3P323_WICAA/50-162               ..EYKQLPDDSMYIEKFYDELDQFKKEIETNKsiTQSN...FSDFEKDPNELIQQLELFIEGKIKPQYVE-------..............-KVMS...KFQ.......MERFDEFLRNVKITLILNGGHPMIFDILLQSKAQFDWFVK-r.
A0A1E4SD60_9ASCO/745-850              ..EYVQIPDDLE-LHKFSDQLECFRDEVLK--..--KP...YRDY--SPDEINSLLDKTIDDVIGKGLVIQ------..............GSNIN...SDT.......IYNYVKLSKRLTRLFNTNGGYTEVLDTLIHSQSVFKDFEKK..
J8QB50_SACAR/53-175                   ..EYKQLPEDSNYIEKHYKELQIFLNEFLIKK..LNKT...YADFEGNPDELVFQLEKFIELEVTPKCTDHSTLNDRer..........kfKSVGD...RIV.......VDRYLDFVKDVRLTLLLNGGHSFIFDVMLQAKDVFDKMQKE..
A0A448YSZ7_BRENA/78-178               ..EYKQLPDDSQFIEEHYDDLLYYRDKLVG--..KDGS...YASLG-TASNLFMKLSEY-----NPELGG-------..............GLLID...KIQ.......---FEKFVGDLVTTLRLNGGHLFTLDLLIQNQREFERMQKK..
A0A1E3QZU5_9ASCO/65-183               ..EYKQLPDDCQYITQHREQLIRFRK-FLQDRhaEKRA...FQSY--TANELSGQLEDFMSQVEKERASQTGF----..............--LAD...KATallldqeLKAFQKMDRGIRKTLHLNNGYTHVFDAILTNFEVFDTMERN..
J7SAH6_KAZNA/50-182                   ..EYRQIPDDSNYIEKFYHELAVFNKVCLENE..LHKS...YSDFEDNPSELVFQVEKFVELQIVPRHSTVRDPNTKdtsgyhipslnvycQHLSD...KLV.......IERYVEFIKAVSLTLRLNGGHTFIFDILLTAKSVYDRLES-d.
Q6CX78_KLULA/44-174                   ..EYKQLPENSNFIDKFYTELQKFHDEFLVPR..LNKH...YTDFDENPDDLVFELEKYIELHIIPSHSVRTQKSDLmaqgin..lpmvycETLGD...KMV.......IERFIEFCRSVRYTLRLNGGHSFIFDIMLQSNSVFQDFEK-s.
A0A2V1AYR1_9ASCO/801-905              .p-YVQIPEKL-GLHDFVDQLSLFREE-----..LQKP...YKDA--SAEEIINLMEKR----TKEVYNNKDSNSAS..............KINTD...NLV.......--SFIKLHAKLKKLLAWNGGNTAILDTLIYSQKVFDNFEA-n.
A0A1V2L649_CYBFA/44-158               ..EYRQLPDDSQYIEKFYSELSSFHSEIVKNNkiPYTS...FSEFENDPNSLITELENFIQTKVYPEYVNK------..............DDLGS...QMV.......IKRYNDFLRNVKITLILNGGHTFIFDILLQNKKLFDGFDH-n.
A0A1G4MCN6_LACFM/41-170               ..EYKQLPLDSDFIEKSYNELEQFSTDFLQKH..LKKS...YSDFENHPDQLVFELEKYIELHVIPRHSVSSGQMVNtgnrv...lpmvycKSMSD...KLV.......IERFLDFCNGVKLTLRLNGGHTCIFDILLQGKAAFDQFEK-r.
A0A1S7HSM8_9SACH/53-183               ..KYKQLPDDSDYIEKFYDELQLFSQDFLEKQ..LHKK...YTDFEECPEELVFQLDQFIELQIIPRYSKPVKETGDnhaafp..lrsiqcKTISD...KIV.......IERYLDFAKGVKLTLMLNGGHTFIFDVLLQAKSVFDNMER-s.
A3LQ95_PICST/669-775                  .s-YVQLPEELE-LHKFSDELTIFSE----DE..LKRP...YKEC--SADEINLLLDSRIDE----VYHGLSNSNP-..............DSRLC...KDN.......VYEFMRLSKRLTRLFTLNGGHTAVLDTLIHSQRVFDDIEKK..
A0A1E4TTU2_PACTA/100-221              ..NYKQLPEDSAFIEQHYDELKKFKEFLINTS..NKKNvtyFKDF--SSSELLEKLDKFIDNCIKPDHELLKQGKKS..............DKDMD...GGEr.....eLEFFQKFKYNLKITLRMNGGHTFILDVLMQNKEAFDNFDKN..
K0KQ56_WICCF/57-169                   ..EYRQLPDDSQYIEKFYEELDLFQKEIVNNSsiKGKN...FSDFEDDPNELIIQLELFIEGKIKPQVSF-------..............-DKLA...RAK.......YERFDEFLRNVKITLVLNGGHPMIFDILLQSKQHFDGFDK-m.
#=GC seq_cons                         ..EY+QLP-DSpaIEKFYcELphFpp-hl.pp..LpKs...YsDFp.sPsELlhpL-KaI-.plhspass..t.tt...............psht-...Khs.......lc+FhcFs+sl+hTLtlNGGHTaIhDhLlQupplFDph-c...
//