#=GF ID FTZ
#=GF AC PF03867.18
#=GF DE Fushi tarazu (FTZ), N-terminal region
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE DOMO:DM07486;
#=GF GA 25.00 25.00;
#=GF TC 33.60 29.70;
#=GF NC 22.10 22.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 11592991
#=GF RT Segmentation gene product Fushi tarazu is an LXXLL
#=GF RT motif-dependent coactivator for orphan receptor FTZ-F1.
#=GF RA Suzuki T, Kawasaki H, Yu RT, Ueda H, Umesono K;
#=GF RL Proc Natl Acad Sci U S A 2001;98:12403-12408.
#=GF DR INTERPRO; IPR005567;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This region contains the important motif (LXXLL) necessary for
#=GF CC the interaction of FTZ with the nuclear receptor FTZ-F1. FTZ is
#=GF CC thought to represents a category of LXXLL motif-dependent
#=GF CC co-activators for nuclear receptors.
#=GF SQ 24
#=GS B4GEM3_DROPE/1-284 AC B4GEM3.1
#=GS A0A3B0KD87_DROGU/1-276 AC A0A3B0KD87.1
#=GS A0A6P8XWX2_DROAB/1-259 AC A0A6P8XWX2.1
#=GS A0A484BVS5_DRONA/58-344 AC A0A484BVS5.1
#=GS A0A0M3QY15_DROBS/1-284 AC A0A0M3QY15.1
#=GS A0A182YEN8_ANOST/76-326 AC A0A182YEN8.1
#=GS B4K6G3_DROMO/1-284 AC B4K6G3.2
#=GS B4QYX9_DROSI/1-251 AC B4QYX9.1
#=GS B2ZIC3_DROSE/1-251 AC B2ZIC3.1
#=GS B4LYV4_DROVI/1-281 AC B4LYV4.1
#=GS A0A6P8Y382_DROAB/1-280 AC A0A6P8Y382.1
#=GS B4NAA7_DROWI/1-267 AC B4NAA7.1
#=GS A0A6P4DY78_DRORH/1-248 AC A0A6P4DY78.1
#=GS A0A6J2U098_DROLE/1-255 AC A0A6J2U098.1
#=GS B4JGL9_DROGR/1-301 AC B4JGL9.1
#=GS A0A6P4J866_DROKI/1-253 AC A0A6P4J866.1
#=GS FTZ_DROME/1-248 AC P02835.2
#=GS F5HK01_ANOGA/2-269 AC F5HK01.1
#=GS A0A6I8VPA2_DROPS/1-280 AC A0A6I8VPA2.1
#=GS A0A811U926_CERCA/1-286 AC A0A811U926.1
#=GS B3M0P9_DROAN/1-260 AC B3M0P9.1
#=GS A0A0L0CR98_LUCCU/1-280 AC A0A0L0CR98.1
#=GS A0A6I9VI56_BACDO/280-356 AC A0A6I9VI56.1
#=GS A0A6I9VI56_BACDO/1-290 AC A0A6I9VI56.1
B4GEM3_DROPE/1-284 .............................MATTNS.QSHY-Y.AD..NMYNMYHHHt.ahSLP...PTYYDN-..---..SYYQSATq..............sTASQWqpsPAGYQ..GNYGAAYG.VQE.SYSDS.CYYAQ..SS......YS.PID.....AT.....VP...QIPAVPAMPA...SQPEP.ILAA..................................SPVKTLKRKAED........-AAAVIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.TVKKSPa.tVPAQI.KASSSPA....PSYEQ..EY.VAAPTP.........................SASEDVDYLDVYSPQSQ.Kn......hKNGEYVagTPPP...lASTPA..TPT.SI--VE......GISTPPQSPGVKSgta......snvSHEINHRIVTAANSGv.aADFNWSHIEESLA.................
A0A3B0KD87_DROGU/1-276 .............................MATTNS.QSHY-Y.AD..NMYNMYHHH....SLP...PTYYDN-..---..SYYQSAAtq............svAASQWqpaASSYQ..SNYGGAAY.GQE.SYSDSsCYYAQ..-S......SY.S--.....PI.....DA...TVPQMP--PA...LQQPE.IPVA..................................SPVKSLKRKAED........TAA-VIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.TVKKSP...AQAQI.KASCSPA....PSYEQ..EY.VAAPTP.........................SASEDVDYLDVYSPQSQ.Kn......hKNGEYVaaTPPP....ASTPA..TPT.SI--VE......GISTPPQSPGVKSata......ssvSHEINHRIVTAASNGv.aAEFNWSHIEESL-s................
A0A6P8XWX2_DROAB/1-259 .............................MAATNS.H---YY.AD..SMYNMYPG-....SLP..pSTYYENS..HSNntGYYQSNS................-----...YASYQ..TNSYPQYS.---.--QES.CYYSS..YQ......EL.MPQ.....ST.....PS...TVISSA----...-----.-ASS..................................PAAKPAKRKATE........MAADIISAV..EERPST....LRALLTNPAKKLKYTPDYFYTTFE.QVKKES..sSKSNS.SSSGELS....PCYEQ..DY.AAVPTPstqqth.............mspqrsSSEQDVDYLDVYSPPPApC........KQ---A..TPA-....--APA..TPA.SL---V......GISTPPQSPAEKAvnq......qqqQNEINHRIVTAGAVS...NEFNWSHIEETLA.................
A0A484BVS5_DRONA/58-344 .............................MAATNT.H---YY.AD..SMYNMYHH-....ALP...STYYDNT..SSS..NYYQ---................SNQGW..qPASYQ..PSSYAHYS.-QE.SYSES.CYYAN..YH......HQ.QQQ.....QQqqlqsQQ...PEQPLCLPALd.aVPQYQ.VPAVseptt.......................neassaAPAKSRKRKAEE........SAAEIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTIE.HVKR--...-PCKS.SSAGELS....PCYEQ..DY.-AVPTPstqqt..............hmspqrSTGEDVDYLDVYSPRKP.A........KHGDFV..TPPP...aATTPV..DGL.GLGLGI......GISTPPQSPAEKS............-NEINHRNVTAANAS...NEFNWSHIEETIA.................
A0A0M3QY15_DROBS/1-284 .............................MATTNS.QSHY-Y.AD..SMYNMYHQHhphhALP..tPTYYDSS..SAS..SYYQTAN................-MASW..qPTNYS..----TQYS.-QE.SYSES.CYYSA..A-......--.-AA.....SY.....QQ...QV--MAAPLP...VPQYQ.QPTPapa............................aapTPVKTLKRKAED.......sSAADIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.HVKK--...-PSKS.SSAGELS....PCYEQ..DY.LAVPTPstqqt..............hmspqrSHSDDVDYLDAYTPRKH.A........KQM-IP..TPPP...aSSTPSsaTPT.PGSLVDn....iGISTPPQSPGEQPt.........nqQPEINQRLLTAASSN...NEFNWSHIEETLA.................
A0A182YEN8_ANOST/76-326 ....................aaigyssag------.------.--..---------....---...-QYYPDG..HFS..SYQFNGR................HQQVD...QCDNQ..YDSYYGYP.YQP.LAHQA.AYGTQ..QQ......QQ.LQA.....GE.....YW...IRANESASSSvgiMSCGK.IGEV..................................AKEPAMKRKYSEe.....dgKPAEKGAAG..EASNATdspaLRALLTNPAKKLKYNPHYASGVAKdTVRR-T...ATTMG.CNSGILS....PAASD..RI.VPDIVP........................lSPNKTDDSIDSLLDNTS.-........KHGVDT..TQGE...nYTLHS..LGQpATPNYD......GVSTPPLSPKDME............S--------------...-------------aisshgpfwnqnges..
B4K6G3_DROMO/1-284 .............................MAATNT.H---YY.AD..SMYNMYHH-....ALP...PTYYDNT.sSSS..SYYQ---................SNQSW..qPASYQ..PSSYAHYS.-QE.SYSES.CYYANyhHQ......QQ.QQT.....QQ.....PQ...QQQPLCLPALd.aVPQYQ.VPTVaepsv........................easspAPAKSRKRKAEE........SAADIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTIE.HVKR--...-PSKS.SSAGELS....PCYEQ..DY.-AVPTPstqqt..............hmspqrSTGEDVDYLDVYSPRKP.A........KHGDFV..TPPP...aATTPV..DGL.GLGLGI......GISTPPQSPAEKS............-NEINHRIVTAANAS...NEFNWSHIEETIA.................
B4QYX9_DROSI/1-251 .............................MATTNS.QSHYSY.ADnmNMYNMYHPH....SLP...PTYYDNS..GSN..AYYQNSS................-----...--TYQ..--SYQGYY.PQE.SYSES.CYYYN..--......NQ.EQM.....-T.....TH...TVPPV-----...-----.QPTT..................................PPPKATKRKAEE........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTVE.QVKKAP..aVTTKV.A--ASPA....PSYEQ..EY.VTVPTP.........................SASEDVDYLDVYSPQSQ.Tq.....klKNGDFA..TPP-....---PT..TPT.SLPPVE......GISTPPQSPGEKSss........avSQEINHRIVTAPNGA...GDFNWSHIEETLA.................
B2ZIC3_DROSE/1-251 .............................MATTNS.QSHYSY.ADnmNMYNMYHPH....SLP...PTYYDNS..GSN..AYYQNSS................-----...--TYQ..--SYQGYY.PQE.SYSES.CYYYN..--......NQ.EQV.....-T.....TQ...TVPPL-----...-----.QPTT..................................PPPKATKRKAEE........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTVE.QVKKAP..aVTTKV.A--ASPA....PSYEQ..EY.VTVPTP.........................SASEDVDYLDVYSPQSQ.Tq.....klKNGDFA..TPP-....---PT..TPT.SLSPVE......GISTPPQSPGEKSss........avSQEINHRIVTAPNGA...GDFNWSHIEETLA.................
B4LYV4_DROVI/1-281 .............................MAATNT.HSHSYY.AD..SMYNMYHH-....ALP...PTYYDNTssGSS..SYYQSNSm..............aSTASW..qPANYQ..AGSYVQYG.-PE.SYSES.CYYAN..YQ......QTtLPQ.....PE.....PA...AVPQYHPTAV..aEPFTK.ANSP..................................APVKSRKRKAEE........SAAEIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTIE.PVKK--...-PSKS.SSAGELS....PCYEQ..DY.-AVPTPstqqt..............hmspqrSTSEDVDYLDVYSPHKQ.A........KHGDFI..TPPP...aATTPA..TPA.SL--VDg....iGISTPPQSPAEKS............-HEINHRIVTAATGN...NEFNWSHIEETLA.................
A0A6P8Y382_DROAB/1-280 .............................MAATNS.H---YY.AD..SMYNMYPG-....SLP..pSTYYENS..HSNntGYYQSNS................-----...YASYQ..TNSYPQYS.---.--QES.CYYSS..YQ......EL.MPQ.....SV.....P-...ASAPAP-ASI...VPQYQ.AAAVetpstv.....................issaassPAAKPAKRKATE........MAADIISAV..EERPST....LRALLTNPAKKLKYTPDYFYTTFE.QVKKES..sSKSNS.SSSGELS....PCYEQ..DY.AAVPTPstqqth.............mspqrsSSEQDVDYLDVYSPPPApC........KQ---A..TPA-....--APA..TPA.SL---V......GISTPPQSPAEKAvnq......qqqQNEINHRIVTAGAVS...NEFNWSHIEETLA.................
B4NAA7_DROWI/1-267 ...........................ma----AS.HSHYYTaAD..SMYNMYHHHh.hlAAPtstSTYYDN-..-YQ..NYQSNTG................SASSW..qSASYQ..QSYSNSYT.NQE.QFTDN.CYYSG..YS.....pEQ.MPV.....YQ.....QQ...EVPSVPEATP...LESLA.LPPP..................................SPPKSLKRKAEEti...tkdTAAAVIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.SVKKAA...VSTKI.T--SSPA....PSYEP..DY.VAAPTP.........................TASEDVDYLDVYSPKTS.-........KNG---..TPPP....STTPA..TPT.SL--VE......GISTPPQSPKEKN............QEQINHRIVT----A...NDFDWSHIEES--qi...............
A0A6P4DY78_DRORH/1-248 .............................MATTNSqQSHYSY.ADnmNMYNMYHPH....SLP...PTYYDNS..ASN..AYYQNSS................-----...--SYQ..--GYQGYY.PQE.SYSES.CYYYN..--......-Q.EQA.....--.....--...---TVT----...--SQT.LPTT..................................PPPKSAKRKAEE........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTVE.PVKKAP...-ASKV.A--ASPA....PSYEQ..EY.VAVPTP.........................CASEDVDYLDVYSPQSQ.Sqk....hlQNGDFA..TPP-....---PT..TPT.SLPPVE......GISTPPQSPGEKSss........vvGQEINHRIVTAPNGA...GDFNWSHIEETLA.................
A0A6J2U098_DROLE/1-255 .........................myag------.------.--..---------....--I...PTYYES-..-GN..NYYHQQ-................-APSW..qPNGVY..ASSYPHHGqDLN.VYNEN.FY--G..FT......EQ.TQE.....RG.....LQ...HCPQNA----...-----.-HIQ..................................SPVKPEKRKAEE........KSEE---AI..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.HVKVAL...GSKKSgTNVSEQSpqtpPSYEQ..DF.-GAPTPltqq.................mhmsPQRSDVDYLDVYSPQSA.KapprttayQHHDYP..TPPPv..aSVTTT..ITT.PDLLVN......GISTPPLSPAVNQhkq......seqKNEINHHILT----A...AEHNWSNIEKRLA.................
B4JGL9_DROGR/1-301 .............................MAATNT.HSHSYY.AD..SMYNMYHH-....GLP...PTYYDN-..-SN..SYYQQSNs.............tsSCSSW...PTSYQ..PSSYAQYG.-QE.SYGES.CYYSNyqHQ......HQ.LQQ.....QQ.....QQ...QTMTMPAPAA...LPHYQ.APAPvsvpvpap..................aaatvttpAPLKSRKRKAEE........SAADIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.QVKK--...-PNRS.SSAGELS....PCYEQ..DY.-AVPTPstqqt..............hmspqrSSSEDVDYLDVYSPRKQ.A........KHGDFV..TPPP...aATTPT..ATT.PASLVDgigigiGISTPPQSPAEK-............-NEINHRNVTAASSSssnNEFNWSHIEETLA.................
A0A6P4J866_DROKI/1-253 .............................MATTNS.QSHYSY.ADnmNMYNMYHPH....SLP...PTYYDNSaaGSS..SYYQTSS................-----...SANYQ..--SYQGYY.SQE.SYSDS.CYYYQ..-N......SQ.EQA.....--.....--...PAQT------...----L.QPTT..................................PPPKATKRKAEE........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTVE.SVKK-P...SPAPA.KAAASPA....PSYEQ..EY.VAVPTP.........................SASEDVDYLDVYSPQSQ.Sq.....kmKNGDFA..TPP-....---PT..TPS.SLPPVE......GISTPPQSPGEKSlp........avSQEINHRIVTAPSGA...ADFNWSHIEESLA.................
FTZ_DROME/1-248 .............................MATTNS.QSHYSY.ADnmNMYNMYHPH....SLP...PTYYDNS..GSN..AYYQNTS................-----...--NYQ..-----GYY.PQE.SYSES.CYYYN..--......NQ.EQV.....-T.....TQ...TVPPV-----...-----.QPTT..................................PPPKATKRKAED........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTVE.QVKKAP..aVSTKV.T--ASPA....PSYDQ..EY.VTVPTP.........................SASEDVDYLDVYSPQSQ.Tq.....klKNGDFA..TPP-....---PT..TPT.SLPPLE......GISTPPQSPGEKSss........avSQEINHRIVTAPNGA...GDFNWSHIEETLA.................
F5HK01_ANOGA/2-269 ..................sipqsqllqns------.------.--..---------....---...-------..---..QYAQQSQqe............iqNISSI..sSSAYG..YSATAQYN.HDE.QFSSN.SLHTR..HHqlenygNQ.FDSyygypYQ.....TT...AHYSLCG---...-----.---Aqehleeyfykpteve...rsnvekrscekscetiK-PPAMKRKISE........KETN---DN..EKDSPA....LRALLTNPAKKLKYNPHYAHSMTN.ESSRRI...EATIG.YNNGFLS....PAASD..RI.VPDIVPls.....................pnKTDDSIDSLLDNSS---.-........-KQDIV..TMQCvdytLNSLR..QIT.ATPKYD......GVSTPPLSPKNME............---------------...-------------saissqgvenhpkessk
A0A6I8VPA2_DROPS/1-280 .............................MATTNS.QSHYY-.TD..NMYNMYHHHt.ahSLP...PTYYDN-..---..SYYQSATq..............sTASQWqpsPASYQ..SNYGAAYG.VQE.SYSDS.CYYAQ..SS......-Y.SP-.....-I.....DA...TVPQIPAVPA...MPEP-.ILAA..................................SPVKRLKRKAED........-AAAVIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTFE.TVKKSPv.tVPVQI.KASSSPA....PSYEQ..EY.VAAPTP.........................SASEDVDYLDVYSPQSQ.Kn......hKNGEYVagTPPP...lASTPA..TPT.SI--VE......GISTPPQSPGVKSata......snvSHEINHRNVTAANSGv.aADFNWSHIEESLA.................
A0A811U926_CERCA/1-286 ......maslnyypeyinannatmaqqqt------.------.--..---------....YAY...ASYYNN-..--N..LSYHELN................ANNSF...MHNRN..AHAHALFA.NQQ.NFEQY.KQLNQ..KC......QK.VYI.....KI.....SK...ETTIQCLN-L...VH---.---KsgefkhtnnsrphykkearkscavgntktiseeaICTQAGKRKFPE........SK-----EI..KEEQSH....LRALLTHPVKKLKYNPDYYKSTTE.KIGSPE...NQTLN.NTANNVN....SDFEN..MAtFAVNSQpifgqdaahnirgistpstlstlpsPGSNGMSCMEEYSPQSM.Rrf...nhsKSSDFI..TPPP....SNDST..TST.GV----......-------------............---------------...-------------vteppllpiptl.....
B3M0P9_DROAN/1-260 ...........................ma-----A.NSHYNYsAEnmNMYNMYHHH....SLP...PTYYDNA..SGN..GYYQASS................-----...--SYQ..--SYQGYY.PQE.NYSEN.CYYYG..--......QQ.EQV.....PQ.....VP...EVPQVT----...----Q.QPAT..................................PPPKAAKRKAEE........DAASIIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTTLE.QVKKTP..aPTTKA.TAAASPA....PSYDQ..EY.VTAPTP.........................STSEDVDYLDVYSPQSA.Qsqs..lklKNGDFA..TPP-....---PT..TPT.SLPPVE......GLSTPPQSPGEKSssa.....ssavSQEINHRIVTGPSNA...NDFNWSHIEETLA.................
A0A0L0CR98_LUCCU/1-280 .............................MAATNF.YTDF-S.SN..STQNMYNY-....SNA...STYYDN-..-TA..SYYHQQQ................SNSTW..nPATYN..PNFMPQYN.NVGlENSSS.QMYND..YY......NY.NNI.....--.....-N...EQVSIN----...-----.-TPE..................................APKTSLKRRASEleeeivskPAAEI-SKVetEEPPSK....LRALLTNPVKKLKYSPDYYYTTFE.KVNSNNnvkTQTEQ.TSVPNTP....PCFEQ..DF.LSAHTPatqq.................silsPNRSDVDYLDVYSPQSL.KvtsnskvyKNGSST..TT--....-SEPA..TPA.SL--VD......GISTPPLSPNDKHinq.....nsaqQHEINHQILT----T...NDYNWSNCEDS--pa...............
A0A6I9VI56_BACDO/280-356 ...................eppslanasa------.------.--..---------....---...-------..---..-------................-----...-----..--------.---.-----.-----..--......--.---.....--.....--...----------...-----.----..................................------------........---------..------....------------------------.------...-----.-------....-----..--.------.........................-----------------.-........-----V..VEPI....KTTLS..TNT.SH--VN......GISTPPLSPHDQTvnqhkeqplqlqQHEINHQILT--DTA...AEFNWSLCED---ns...............
A0A6I9VI56_BACDO/1-290 mattnyyaeyanntmmtqqqayaysgyys------.------.--..---------....-NN...TPYYDTT..SGN..NFMHNLDhtrfskayhpsydqfkSNQVKt.aEQIYEgeAWSYNNTA.SAE.SYCQY.IGYKN..TT......NQ.ENS.....DV.....GKdeaKNSPV-VVAD...LNTFEdKQTN..................................QPIKRKHFECEE........N----LSQE..TEKPST....LRSLLTNPAKKLKYNPNYFFTTME.KVSS--...PNKQS.TSKCNLN....SMSDNgtGY.-SVSAPpsldqdvaadgsrmstpsthstlpsPSRTEMSYLEAYSPQSL.Kql...nhgKTSDYL..TPPPsnasATLPT..TTI.E-----......-------------............---------------...-------------ppslanasav.......
#=GC seq_cons .............................MAsTNo.p....Y.AD..sMYNMYH......uLP...sTYYDN....us..uYYQsss.........................ssYQ...tuastYs..QE.sYS-S.CYYss...p......pp..t..............t...pssshs..............sss..................................sPsKutKRKAEE........sAAslIAAV..EERPST....LRALLTNPVKKLKYTPDYFYTThE.pVKK.....ssops.sssup.u....PsYEQ..-Y.husPTP.........................Ssu-DVDYLDVYSPpot.p........KpG-as..TPP......ssPs..TPT.Sl..V-......GISTPPQSPu-Ks............ppEINHRIVTAsssu...s-FNWSHIEEoLA.................
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