#=GF ID   FhbB
#=GF AC   PF20813.1
#=GF DE   Factor H binding protein B
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:3412.1.1
#=GF GA   27.00 27.00;
#=GF TC   27.60 33.70;
#=GF NC   26.00 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF RC   Paper describing PDB structure 3qz0
#=GF RN   [1]
#=GF RM   22371503
#=GF RT   Structure of factor H-binding protein B (FhbB) of the
#=GF RT   periopathogen, Treponema denticola: insights into progression of
#=GF RT   periodontal disease.
#=GF RA   Miller DP, Bell JK, McDowell JV, Conrad DH, Burgner JW, Heroux
#=GF RA   A, Marconi RT;
#=GF RL   J Biol Chem. 2012;287:12715-12722.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Treponema denticola, a human pathogen that contributes to
#=GF CC   periodontitis, survives by binding factor H (FH) to its surface
#=GF CC   through its Factor H binding protein B (FhbB). The structure of
#=GF CC   this protein is highly ordered consisting of an alpha-beta fold.
#=GF CC   This highly thermostable protein forms a weak dimer with an
#=GF CC   interface occurring along one alpha helix from each subunit in
#=GF CC   an anti-parallel alignment with no direct hydrogen bonding
#=GF CC   between the subunits [1].
#=GF SQ   8
#=GS E7NRT3_TREPH/1-70     AC E7NRT3.1
#=GS E7NPQ4_TREPH/14-89    AC E7NPQ4.1
#=GS E7NTD1_TREPH/80-159   AC E7NTD1.1
#=GS E7NRV9_TREPH/54-128   AC E7NRV9.1
#=GS Q73RI0_TREDE/26-101   AC Q73RI0.1
#=GS E7NTD1_TREPH/173-252  AC E7NTD1.1
#=GS E7NRV9_TREPH/139-205  AC E7NRV9.1
#=GS E7NTD1_TREPH/1-65     AC E7NTD1.1
E7NRT3_TREPH/1-70                ...mdg----------------LVAEAKDKDISSVKIAAKL..VFVNAEMLkNIKkddkkYpVIKDERPSEKIEKGTTKAQLKKRFTV---tta
E7NPQ4_TREPH/14-89               tseema------RDIYDNAMQDFAAHLKESGATADMVVEQV..EYLNPYLS.QFG.....W.KVVDNNPGTDLAQGTTVEQLKERFTLQKI...
E7NTD1_TREPH/80-159              ......DMNNEQIECYDKFITDLETAAELTDVLPIAVQTSV..KVVAKQME.GIQgk.tkY.TIVDKKPGDSITKGTKKEALQQRFMIEKA...
E7NRV9_TREPH/54-128              .....p-TEAVQKT-YDAALEELAAHLKDSGATADEVVEVV..EDLNMELL.RFG.....W.KVVDKKTGTDLAQGTTVEQLKERFTLEKV...
Q73RI0_TREDE/26-101              ......KMNTAQKAHYEKFINALENELKTRHIPAGAVIDML..AEINTEAL.ALD.....Y.QIVDKKPGTSIAQGTKAAALRKRFIPKKI...
E7NTD1_TREPH/173-252             ......AMSNEQKIYYDTFIFSLATRAAITILPADTVKNMT..KTAAEHME.NISgt.akY.TIKDKMPNMPVLQGTKKEALEKRFVAEKV...
E7NRV9_TREPH/139-205             ....pp--EAVQKR-YDDAMQGLADELERSDFPADEVVAGV..RYLNMDLS.RFG.....W.KVVDKKAGTGLAQGTTVEQLK--------...
E7NTD1_TREPH/1-65                .....m-------------LASLETLANFNDVPAEIVKMHVllGSANLKAA.KSK.....L.KIVDKNEGKPIAKGTTKDALEKRFVLE--e..
#=GC seq_cons                    ........ps.Q+t.YDphlpsLsschcpoclsA-tVhstV..chlNhcht.phs.....a.pIVDK+PGsslAQGTTtEtL+cRFslcKh...
//