#=GF ID Flavi_capsid
#=GF AC PF01003.23
#=GF DE Flavivirus capsid protein C
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_156 (release 3.0)
#=GF GA 27.00 27.00;
#=GF TC 27.20 93.80;
#=GF NC 24.00 20.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 9499070
#=GF RT Signal peptidase cleavage at the flavivirus C-prM junction:
#=GF RT dependence on the viral NS2B-3 protease for efficient processing
#=GF RT requires determinants in C, the signal peptide, and prM.
#=GF RA Stocks CE, Lobigs M;
#=GF RL J Virol 1998;72:2141-2149.
#=GF RN [2]
#=GF RM 9201220
#=GF RT A conserved internal hydrophobic domain mediates the stable
#=GF RT membrane integration of the dengue virus capsid protein.
#=GF RA Markoff L, Falgout B, Chang A;
#=GF RL Virology 1997;233:105-117.
#=GF DR INTERPRO; IPR001122;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Flaviviruses are small enveloped viruses with virions comprised
#=GF CC of 3 proteins called C, M and E. Multiple copies of the C
#=GF CC protein form the nucleocapsid, which contains the ssRNA
#=GF CC molecule.
#=GF SQ 3
#=GS POLG_YEFV1/5-122 AC P03314.1
#=GS POLG_ZIKV/6-123 AC Q32ZE1.1
#=GS POLG_DEN1W/5-117 AC P17763.2
POLG_YEFV1/5-122 .....KAQGKTLGVNMVRRGVRSL..-SNKIKQKTKQIGNRPGPSRGVQGFIFFFLfniLTGKKITAHLKRLWKMLDPRQGLAVLRKVKRVVASLMRGLSSRKRRSHDVLTVQFLILGM--LLM---tggv
POLG_ZIKV/6-123 eeirr-----IRIVNMLKRGVARV.nPLGGLKRLPAGLLLGHGPIRMVLAILAFLR...FTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKERKRRGADTSIGIIGL-LLTTAMAa...
POLG_DEN1W/5-117 ....r-KKTGRPSFNMLKRARNRVstVSQLAKRFSKGLLSGQGPMKLVMAFIAFLR...FLAIPPTAGILARWGSFKKNGAIKVLRGFKKEISNMLNIMNRRKRS-------VTMLLML--LPTAL-afhl
#=GC seq_cons ....R.tpstphuVNMLKRGVsRV.ssSstlKRhoKGLLsGpGPhRhVhAFIAFLR...FTAIKPTAGLlsRWGSlcK+pAlcVLRKFKK-lAuMLRIlNuRKRRp+cshssshhILGL..LsTAh.Ahtl
//